| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Peiguo Ding, Jian Huang, Pavan K Battiprolu, Joseph A Hill, Kristine E Kamm, James T Stul. Cardiac myosin light chain kinase is necessary for myosin regulatory light chain phosphorylation and cardiac performance in vivo. The Journal of biological chemistry. vol 285. issue 52. 2011-01-24. PMID:20943660. |
isoproterenol infusion elicited hypertrophic cardiac responses in wild type mice. |
2011-01-24 |
2023-08-12 |
mouse |
| Peiguo Ding, Jian Huang, Pavan K Battiprolu, Joseph A Hill, Kristine E Kamm, James T Stul. Cardiac myosin light chain kinase is necessary for myosin regulatory light chain phosphorylation and cardiac performance in vivo. The Journal of biological chemistry. vol 285. issue 52. 2011-01-24. PMID:20943660. |
in mice lacking cmlck, the hypertrophic hearts showed no additional increases in size with the isoproterenol treatment, suggesting a lack of rlc phosphorylation blunted the stress response. |
2011-01-24 |
2023-08-12 |
mouse |
| Guo-Xing Zhang, Shoji Kimura, Koji Murao, Xiao Yu, Koji Obata, Hiroko Matsuyoshi, Miyako Takak. Effects of angiotensin type I receptor blockade on the cardiac Raf/MEK/ERK cascade activated via adrenergic receptors. Journal of pharmacological sciences. vol 113. issue 3. 2010-11-24. PMID:20562518. |
chronic isoproterenol (iso)-induced cardiac hypertrophy was inhibited in wild-type mice and at1ar(-/-) mice treated with the arb candesartan (cv11974). |
2010-11-24 |
2023-08-12 |
mouse |
| Jwu-Lai Yeh, Jong-Hau Hsu, Ping-Ju Wu, Shu-Fen Liou, Chung-Pin Liu, Ing-Jun Chen, Bin-Nan Wu, Zen-Kong Dai, Jiunn-Ren W. KMUP-1 attenuates isoprenaline-induced cardiac hypertrophy in rats through NO/cGMP/PKG and ERK1/2/calcineurin A pathways. British journal of pharmacology. vol 159. issue 5. 2010-07-13. PMID:20132211. |
to determine whether kmup-1, a novel xanthine-based derivative, attenuates isoprenaline (iso)-induced cardiac hypertrophy in rats, and if so, whether the anti-hypertrophic effect is mediated by the nitric oxide (no) pathway. |
2010-07-13 |
2023-08-12 |
rat |
| Michael P Czubryt, Lise Lamoureux, Angela Ramjiawan, Bernard Abrenica, Jaganmohan Jangamreddy, Kristin Swa. Regulation of cardiomyocyte Glut4 expression by ZAC1. The Journal of biological chemistry. vol 285. issue 22. 2010-06-17. PMID:20363751. |
induction of hypertrophy by phenylephrine or isoproterenol resulted in increased zac1 expression. |
2010-06-17 |
2023-08-12 |
rat |
| Caroline Nunn, Min-Xu Zou, Alina J Sobiesiak, Anju A Roy, Lorrie A Kirshenbaum, Peter Chidia. RGS2 inhibits beta-adrenergic receptor-induced cardiomyocyte hypertrophy. Cellular signalling. vol 22. issue 8. 2010-06-08. PMID:20362664. |
in this study, we investigated the potential role of regulator of g protein signalling 2 (rgs2) in modulating the hypertrophic effects of the beta-ar agonist isoproterenol (iso) in rat neonatal ventricular cardiomyocytes. |
2010-06-08 |
2023-08-12 |
human |
| b' Andrea Mikusov\\xc3\\xa1, Eva Kr\\xc3\\xa1lov\\xc3\\xa1, Lucia Tylkov\\xc3\\xa1, Marta Novotov\\xc3\\xa1, Tatiana Stankovicov\\xc3\\xa. Myocardial remodelling induced by repeated low doses of isoproterenol. Canadian journal of physiology and pharmacology. vol 87. issue 8. 2010-05-06. PMID:19767889.' |
repeated administration of isoproterenol led to hypertrophy, characterized by the existence of myocytes with simultaneous signs of both mature and postnatally developing cardiomyocytes. |
2010-05-06 |
2023-08-12 |
rat |
| Kun Wang, Bo Long, Jing Zhou, Pei-Feng L. miR-9 and NFATc3 regulate myocardin in cardiac hypertrophy. The Journal of biological chemistry. vol 285. issue 16. 2010-05-06. PMID:20177053. |
our results show that myocardin expression is elevated in response to hypertrophic stimulation with isoproterenol and aldosterone. |
2010-05-06 |
2023-08-12 |
Not clear |
| Kun Wang, Bo Long, Jing Zhou, Pei-Feng L. miR-9 and NFATc3 regulate myocardin in cardiac hypertrophy. The Journal of biological chemistry. vol 285. issue 16. 2010-05-06. PMID:20177053. |
however, the hypertrophic stimulation with isoproterenol and aldosterone leads to a decrease in the expression levels of mir-9. |
2010-05-06 |
2023-08-12 |
Not clear |
| Robert Lukowski, Sergei D Rybalkin, Florian Loga, Veronika Leiss, Joseph A Beavo, Franz Hofman. Cardiac hypertrophy is not amplified by deletion of cGMP-dependent protein kinase I in cardiomyocytes. Proceedings of the National Academy of Sciences of the United States of America. vol 107. issue 12. 2010-04-16. PMID:20212138. |
we have compared the effect of isoproterenol (iso) and transverse aortic constriction (tac) on hypertrophy in wt [control (ctr)] mice, total cgki-ko mice, and cgkibeta rescue mice (betarm) lacking cgki specifically in cardiomyocytes (cms). |
2010-04-16 |
2023-08-12 |
mouse |
| L C Heather, A F Catchpole, D J Stuckey, M A Cole, C A Carr, K Clark. Isoproterenol induces in vivo functional and metabolic abnormalities: similar to those found in the infarcted rat heart. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. vol 60. issue 3. 2010-03-30. PMID:19826179. |
chronic isoproterenol administration produces a rapid, highly reproducible rodent model of cardiac hypertrophy. |
2010-03-30 |
2023-08-12 |
rat |
| L C Heather, A F Catchpole, D J Stuckey, M A Cole, C A Carr, K Clark. Isoproterenol induces in vivo functional and metabolic abnormalities: similar to those found in the infarcted rat heart. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. vol 60. issue 3. 2010-03-30. PMID:19826179. |
in conclusion, isoproterenol infusion impaired in vivo cardiac function, induced hypertrophy, and decreased both fatty acid and glucose metabolism, changes similar in direction and magnitude to those found in the rat heart following moderate severity myocardial infarction. |
2010-03-30 |
2023-08-12 |
rat |
| Miguel Copaja Soto, Rodrigo Valenzuela, Adiela Saldaña, María Paz Ocaranza, Jorge E Jalil, Carlos Vio, Paul Lijnen, Gamaliel E Ordenes, Raul Vivar Sanchez, Sergio Lavandero, Guillermo Díaz-Aray. Early expression of monocyte chemoattractant protein-1 correlates with the onset of isoproterenol-induced cardiac fibrosis in rats with distinct angiotensin-converting enzyme polymorphism. Journal of the renin-angiotensin-aldosterone system : JRAAS. vol 9. issue 3. 2010-01-13. PMID:18957386. |
isoproterenol treatment of brown norway and lewis rats (high and low plasma angiotensin-i-converting enzyme activity, respectively) results in similar cardiac hypertrophy but higher cardiac fibrosis in brown norway rats. |
2010-01-13 |
2023-08-12 |
rat |
| Hiroyuki Nakayama, Ilona Bodi, Robert N Correll, Xiongwen Chen, John Lorenz, Steven R Houser, Jeffrey Robbins, Arnold Schwartz, Jeffery D Molkenti. alpha1G-dependent T-type Ca2+ current antagonizes cardiac hypertrophy through a NOS3-dependent mechanism in mice. The Journal of clinical investigation. vol 119. issue 12. 2010-01-11. PMID:19920353. |
conversely, alpha1g-/- mice displayed enhanced hypertrophic responses following pressure overload or isoproterenol infusion. |
2010-01-11 |
2023-08-12 |
mouse |
| Beshay N M Zordoky, Mona E Aboutabl, Ayman O S El-Kad. Modulation of cytochrome P450 gene expression and arachidonic acid metabolism during isoproterenol-induced cardiac hypertrophy in rats. Drug metabolism and disposition: the biological fate of chemicals. vol 36. issue 11. 2009-11-13. PMID:18725507. |
our results show that isoproterenol treatment significantly increased the heart/body weight ratio and the hypertrophic markers. |
2009-11-13 |
2023-08-12 |
rat |
| Juliano L Sartoretto, Benjamin Y Jin, Michael Bauer, Frank B Gertler, Ronglih Liao, Thomas Miche. Regulation of VASP phosphorylation in cardiac myocytes: differential regulation by cyclic nucleotides and modulation of protein expression in diabetic and hypertrophic heart. American journal of physiology. Heart and circulatory physiology. vol 297. issue 5. 2009-11-12. PMID:19734360. |
moreover, there is further increase in vasp phosphorylation in cells isolated from hypertrophic hearts following isoproterenol treatment. |
2009-11-12 |
2023-08-12 |
mouse |
| Wesley W Brooks, Chester H Conra. Isoproterenol-induced myocardial injury and diastolic dysfunction in mice: structural and functional correlates. Comparative medicine. vol 59. issue 4. 2009-11-09. PMID:19712573. |
isoproterenol induced marked endocardial injury, associated with hypertrophy of surviving myocytes, and an increase in myocardial fibrosis (collagen types i and iii according to picrosirius red microscopy). |
2009-11-09 |
2023-08-12 |
mouse |
| Zhiqiang Lin, Iram Murtaza, Kun Wang, Jianqin Jiao, Jie Gao, Pei-Feng L. miR-23a functions downstream of NFATc3 to regulate cardiac hypertrophy. Proceedings of the National Academy of Sciences of the United States of America. vol 106. issue 29. 2009-08-25. PMID:19574461. |
the results showed that mir-23a expression was up-regulated upon treatment with the hypertrophic stimuli including isoproterenol and aldosterone. |
2009-08-25 |
2023-08-12 |
Not clear |
| Wen Yin, Peng Zhang, Jing Hui Huang, Quan Yu Zhang, Rong Fan, Juan Li, Jing Jun Zhou, Yu Zhen Hu, Hai Tao Guo, Shu Miao Zhang, Yue Min Wang, Alan David Kaye, Chun Hu Gu, Jin Cheng Liu, Liang Cheng, Qin Cui, Ding Hua Yi, Jian Ming Pe. Stimulation of kappa-opioid receptor reduces isoprenaline-induced cardiac hypertrophy and fibrosis. European journal of pharmacology. vol 607. issue 1-3. 2009-07-07. PMID:19233160. |
cardiac hypertrophy and fibrosis were developed by intraperitoneal administration of isoprenaline (ip. |
2009-07-07 |
2023-08-12 |
rat |
| Wen Yin, Peng Zhang, Jing Hui Huang, Quan Yu Zhang, Rong Fan, Juan Li, Jing Jun Zhou, Yu Zhen Hu, Hai Tao Guo, Shu Miao Zhang, Yue Min Wang, Alan David Kaye, Chun Hu Gu, Jin Cheng Liu, Liang Cheng, Qin Cui, Ding Hua Yi, Jian Ming Pe. Stimulation of kappa-opioid receptor reduces isoprenaline-induced cardiac hypertrophy and fibrosis. European journal of pharmacology. vol 607. issue 1-3. 2009-07-07. PMID:19233160. |
increases in heart weight, heart-to-body ratio, diameter of cardiomyocytes, and morphological hypertrophic alterations induced by isoprenaline were significantly attenuated by u50,488h(i.p. |
2009-07-07 |
2023-08-12 |
rat |