| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Cong-Ting Guo, Blake D Jardin, Jun-Sen Lin, Rachelle L Ambroise, Ze Wang, Lu-Zi Yang, Neil Mazumdar, Fu-Jian Lu, Qing Ma, Yang-Po Cao, Can-Zhao Liu, Kai-Long Li, Xu-Jie Liu, Feng Lan, Ming-Ming Zhao, Han Xiao, Er-Dan Dong, William T Pu, Yu-Xuan Gu. In vivo proximity proteomics uncovers palmdelphin (PALMD) as a Z-disc-associated mitigator of isoproterenol-induced cardiac injury. Acta pharmacologica Sinica. 2024-07-23. PMID:39043970. |
germline and cardiomyocyte-specific palmd knockout mice were grossly normal at baseline but exhibited compromised cardiac hypertrophy and aggravated cardiac injury upon long-term isoproterenol treatment. |
2024-07-23 |
2024-07-26 |
mouse |
| Patricia Perez-Bonilla, Brianna LaViolette, Bidur Bhandary, Soumya Ullas, Xian Chen, Dinesh Hirenallur-Shanthapp. Isoproterenol induced cardiac hypertrophy: A comparison of three doses and two delivery methods in C57BL/6J mice. PloS one. vol 19. issue 7. 2024-07-22. PMID:39038017. |
isoproterenol induced cardiac hypertrophy: a comparison of three doses and two delivery methods in c57bl/6j mice. |
2024-07-22 |
2024-07-25 |
mouse |
| Jerome Ndudi Asiwe, Abayomi M Ajayi, Benneth Ben-Azu, Adesoji Adedipe Fasanmad. Vincristine attenuates isoprenaline-induced cardiac hypertrophy in male Wistar rats via suppression of ROS/NO/NF-қB signalling pathways. Microvascular research. 2024-06-16. PMID:38880384. |
this study investigated the effects of vcr on isoprenaline (iso), a beta-adrenergic receptor agonist, induced cardiac hypertrophy in male wistar rats. |
2024-06-16 |
2024-06-19 |
rat |
| Zhong-Yan Zhou, Jie Ma, Wai-Rong Zhao, Wen-Ting Shi, Jing Zhang, Yan-Yan Hu, Mei-Yan Yue, Wen-Long Zhou, Hua Yan, Jing-Yi Tang, Yu Wan. Qiangxinyin formula protects against isoproterenol-induced cardiac hypertrophy. Phytomedicine : international journal of phytotherapy and phytopharmacology. vol 130. 2024-06-14. PMID:38810550. |
we found that qxy significantly protected against isoproterenol (iso)-induced cardiac hypertrophy and dysfunction in zebrafish. |
2024-06-14 |
2024-06-17 |
zebrafish |
| Yumei Qiu, Mengdie Xie, Xiaoyun Ding, Hao Zhang, Hongming Li, Hu Wang, Tingting Li, Wei Dong, Fangqin Jiang, Xilan Tan. Inhibition of Cholesteryl Ester Transfer Protein Contributes to the Protection of Ginsenoside Re Against Isoproterenol-Induced Cardiac Hypertrophy. Cureus. vol 16. issue 5. 2024-06-10. PMID:38854305. |
this study aimed to investigate the therapeutic effects and underlying mechanism of re on isoproterenol (iso)-induced cardiac hypertrophy |
2024-06-10 |
2024-06-14 |
Not clear |
| Steeve Akumwami, Kento Kitada, Yoshihide Fujisawa, Netish Kumar Kundo, Md Moshiur Rahman, Asahiro Morishita, Hiroaki Kitamura, Asadur Rahman, Yuichi Ogino, Akira Nishiyam. The Journal of pharmacology and experimental therapeutics. 2024-06-07. PMID:38849140. |
continuous isoproterenol administration for 14 days induced cardiac hypertrophy, associated with sodium-driven water retention in the heart, increased the total body sodium, potassium and water contents at the tissue level, and increased the water intake and blood pressure of the mice. |
2024-06-07 |
2024-06-10 |
mouse |
| Vaishnavi Golatkar, Lokesh Kumar Bhat. Artesunate attenuates isoprenaline induced cardiac hypertrophy in rats via SIRT1 inhibiting NF-κB activation. European journal of pharmacology. 2024-06-06. PMID:38843948. |
artesunate attenuates isoprenaline induced cardiac hypertrophy in rats via sirt1 inhibiting nf-κb activation. |
2024-06-06 |
2024-06-10 |
rat |
| Vaishnavi Golatkar, Lokesh Kumar Bhat. Artesunate attenuates isoprenaline induced cardiac hypertrophy in rats via SIRT1 inhibiting NF-κB activation. European journal of pharmacology. 2024-06-06. PMID:38843948. |
the present study aimed to investigate the effect of artesunate against isoprenaline induced cardiac hypertrophy in rats via sirt1 inhibiting nf-κb activation. |
2024-06-06 |
2024-06-10 |
rat |
| Vaishnavi Golatkar, Lokesh Kumar Bhat. Artesunate attenuates isoprenaline induced cardiac hypertrophy in rats via SIRT1 inhibiting NF-κB activation. European journal of pharmacology. 2024-06-06. PMID:38843948. |
experimental cardiac hypertrophy was induced in rats by subcutaneous administration of isoprenaline (5 mg/kg) for 14 days. |
2024-06-06 |
2024-06-10 |
rat |
| Ramison Santos, Patrick Turck, Victor de Mello Palma, Fernanda Visioli, Vanessa Duarte Ortiz, Isabel Cristina Teixeira Proença, Tânia Regina G Fernandes, Elissa Fernandes, Silvio Tasca, Cristina Campos Carraro, Adriane Belló-Klein, Alex Sander da Rosa Araujo, Neelam Khaper, Alexandre Luz de Castr. MELATONIN IMPROVES NITRIC OXIDE BIOAVAILABILITY IN ISOPROTERENOL INDUCED MYOCARDIAL INJURY. Molecular and cellular endocrinology. 2024-05-26. PMID:38797355. |
animals that received isoproterenol demonstrated a reduction in left ventricle systolic and diastolic diameter, indicating the presence of concentric hypertrophy. |
2024-05-26 |
2024-05-31 |
rat |
| Ubaid Tariq, Soumalya Sarkar, Navya Malladi, Roshan Kumar, Paramesha Bugga, Praloy Chakraborty, Sanjay K Banerje. Knockdown of SCN5A alters metabolic-associated genes and aggravates hypertrophy in the cardiomyoblast. Molecular biology reports. vol 51. issue 1. 2024-05-17. PMID:38758505. |
therefore, to understand the loss of scn5a function in cardiomyocytes, we have knocked down the scn5a gene (scn5a-kd) in h9c2 cells and explored the cell phenotype and molecular behaviors in the presence and absence of isoproterenol (iso), an adrenergic receptor agonist that induces cardiac hypertrophy. |
2024-05-17 |
2024-05-27 |
Not clear |
| Siling Liu, Linjie Su, Jie Li, Yuexin Zhang, Xiaopei Hu, Pengcheng Wang, Peiqing Liu, Jiantao Y. Inhibition of miR-146b-5p alleviates isoprenaline-induced cardiac hypertrophy via regulating DFCP1. Molecular and cellular endocrinology. 2024-04-22. PMID:38649132. |
isoprenaline (iso) treatment induced significant hypertrophy and markedly enhanced the expression of mir-146b-5p in cultured neonatal rat cardiomyocytes and hearts of c57bl/6 mice. |
2024-04-22 |
2024-04-26 |
mouse |
| Anna De Bartolo, Teresa Pasqua, Naomi Romeo, Vittoria Rago, Ida Perrotta, Francesca Giordano, Maria Concetta Granieri, Alessandro Marrone, Rosa Mazza, Maria Carmela Cerra, Benjamin Lefranc, Jérôme Leprince, Youssef Anouar, Tommaso Angelone, Carmine Rocc. The redox-active defensive Selenoprotein T as a novel stress sensor protein playing a key role in the pathophysiology of heart failure. Journal of translational medicine. vol 22. issue 1. 2024-04-20. PMID:38643121. |
here, we investigated the role of selenot in the pathophysiology of hf: (i) by designing a small peptide (pselt), recapitulating selenot activity via the redox site, and assessed its beneficial action in a preclinical model of hf [aged spontaneously hypertensive heart failure (shhf) rats] and against isoproterenol (iso)-induced hypertrophy in rat ventricular h9c2 and adult human ac16 cardiomyocytes; (ii) by evaluating the selenot intra-cardiomyocyte production and secretion under hypertrophied stimulation. |
2024-04-20 |
2024-04-23 |
human |
| Xiao-Yun Ding, Hao Zhang, Yu-Mei Qiu, Meng-Die Xie, Hu Wang, Zheng-Yu Xiong, Ting-Ting Li, Chun-Ni He, Wei Dong, Xi-Lan Tan. Cardioprotective Potential of Cymbopogon citratus Essential Oil against Isoproterenol-induced Cardiomyocyte Hypertrophy: Possible Involvement of NLRP3 Inflammasome and Oxidative Phosphorylation Complex Subunits. Current medical science. 2024-04-19. PMID:38639827. |
in this study, we investigated the cardioprotective effects and mechanisms of the essential oil, the main active ingredient of cymbopogon citratus, on isoproterenol (iso)-induced cardiomyocyte hypertrophy. |
2024-04-19 |
2024-04-21 |
Not clear |
| Hui Fu, Bin Kong, Wei Shuai, Jun Zhu, Xi Wang, Yanhong Tang, He Huang, Congxin Huan. Leukocyte Ig-like receptor B4 (Lilrb4a) alleviates cardiac dysfunction and isoproterenol-induced arrhythmogenic remodeling associated with cardiac fibrosis and inflammation. Heart rhythm. 2024-04-18. PMID:38636927. |
in the isoproterenol (iso) induced animal model, it is often accompanied by myocardial hypertrophy, fibrosis, and inflammation. |
2024-04-18 |
2024-04-21 |
mouse |
| Kai He, Xiaoying Wang, Tingting Li, Yanfei Li, Linlin M. Chlorogenic Acid Attenuates Isoproterenol Hydrochloride-Induced Cardiac Hypertrophy in AC16 Cells by Inhibiting the Wnt/β-Catenin Signaling Pathway. Molecules (Basel, Switzerland). vol 29. issue 4. 2024-02-24. PMID:38398512. |
chlorogenic acid attenuates isoproterenol hydrochloride-induced cardiac hypertrophy in ac16 cells by inhibiting the wnt/β-catenin signaling pathway. |
2024-02-24 |
2024-02-26 |
Not clear |
| Zhuo-Jing Yang, Chun-Ling Guo, Yu-Xin Gong, Long Li, Li-Li Wang, Hui-Min Liu, Ji-Min Cao, Zhao-Yang L. Dapagliflozin Suppresses Isoprenaline-Induced Cardiac Hypertrophy via Inhibition of Mitochondrial Fission. Journal of cardiovascular pharmacology. 2024-02-06. PMID:38030139. |
by continuously infusing isoprenaline (iso) for two weeks using a subcutaneous osmotic pump, a cardiac hypertrophic model was established in male c57bl/6 mice. |
2024-02-06 |
2024-02-09 |
mouse |
| Jacob J Russell, Srinivas Mummidi, Vincent G Demarco, Laurel A Grisanti, Chastidy A Bailey, Shawn B Bender, Bysani Chandraseka. Integrated miRNA-mRNA networks underlie attenuation of chronic β-adrenergic stimulation-induced cardiac remodeling by minocycline. Physiological genomics. 2024-02-05. PMID:38314697. |
isoproterenol infusion induced cardiac hypertrophy, with no change in cardiac function, that was prevented by minocycline. |
2024-02-05 |
2024-02-09 |
mouse |
| Zeyu Li, Ou Hu, Suowen Xu, Chenjia Lin, Wenjing Yu, Dinghu Ma, Jing Lu, Peiqing Li. The SIRT3-ATAD3A axis regulates MAM dynamics and mitochondrial calcium homeostasis in cardiac hypertrophy. International journal of biological sciences. vol 20. issue 3. 2024-01-22. PMID:38250153. |
atad3a prevents isoproterenol (iso)-induced mitochondrial calcium accumulation, improving mitochondrial dysfunction and er stress, which preserves cardiac function and attenuates cardiac hypertrophy. |
2024-01-22 |
2024-01-24 |
Not clear |
| Jiachen Xu, Shiqi Liang, Qinyan Wang, Qingsong Zheng, Mengyang Wang, Jinfu Qian, Tianxiang Yu, Shuaijie Lou, Wu Luo, Hao Zhou, Guang Lian. JOSD2 mediates isoprenaline-induced heart failure by deubiquitinating CaMKIIδ in cardiomyocytes. Cellular and molecular life sciences : CMLS. vol 81. issue 1. 2024-01-10. PMID:38195959. |
in this study, we demonstrated that deficiency of a deubiquitinase, josephin domain-containing protein 2 (josd2), ameliorated isoprenaline (iso)- and myocardial infarction (mi)-induced cardiac hypertrophy, fibrosis, and dysfunction both in vitro and in vivo. |
2024-01-10 |
2024-01-13 |
Not clear |