| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ting-Ting Yu, Li-Jun Sun, Chen Chen, Zi-Jian Wang, Xue-Sheng Liu, Feng-Qin Zhu, Shan Ga. Xin-Ji-Er-Kang Alleviates Isoproterenol-Induced Myocardial Hypertrophy in Mice through the Nrf2/HO-1 Signaling Pathway. Evidence-based complementary and alternative medicine : eCAM. vol 2022. 2022-09-01. PMID:36045660. |
we hypothesized that xjek may prevent isoproterenol (iso)-induced myocardial hypertrophy (mh) in mice by ameliorating oxidative stress (os) through a mechanism that may be related to the nuclear factor erythroid 2-related factor 2 (nrf2)/heme oxygenase-1(ho-1) pathways. |
2022-09-01 |
2023-08-14 |
mouse |
| Faiza Shaikh, Lokesh Kumar Bhat. Cardioprotective effect of Polymyxin-B and Dantrolene combination on isoproterenol-induced hypertrophic cardiomyopathy in rats, via attenuation of Calmodulin-dependent protein kinase II. Chemistry & biodiversity. 2022-08-29. PMID:36037238. |
hypertrophic cardiomyopathy was induced in rats by subcutaneous administration of isoproterenol (5 mg/kg) for 14 days. |
2022-08-29 |
2023-08-14 |
rat |
| Faiza Shaikh, Lokesh Kumar Bhat. Cardioprotective effect of Polymyxin-B and Dantrolene combination on isoproterenol-induced hypertrophic cardiomyopathy in rats, via attenuation of Calmodulin-dependent protein kinase II. Chemistry & biodiversity. 2022-08-29. PMID:36037238. |
administration of isoproterenol for 14 days resulted in severe myocardial damage, characterized by cardiac hypertrophy and increase serum ck-mb, ck-nac, ldh, ast, and alt levels. |
2022-08-29 |
2023-08-14 |
rat |
| Li Xu, Qiong Liu, Tianyi Long, Liming Peng, Fei Li, Zelin Sun, Qiying Xi. Ectopic Acsl6 overexpression partially improves Isoproterenol (ISO)-induced cardiac hypertrophy in vivo and cardiomyocyte hypertrophy in vitro. Journal of cardiovascular pharmacology. 2022-08-17. PMID:35976155. |
ectopic acsl6 overexpression partially improves isoproterenol (iso)-induced cardiac hypertrophy in vivo and cardiomyocyte hypertrophy in vitro. |
2022-08-17 |
2023-08-14 |
mouse |
| Li Xu, Qiong Liu, Tianyi Long, Liming Peng, Fei Li, Zelin Sun, Qiying Xi. Ectopic Acsl6 overexpression partially improves Isoproterenol (ISO)-induced cardiac hypertrophy in vivo and cardiomyocyte hypertrophy in vitro. Journal of cardiovascular pharmacology. 2022-08-17. PMID:35976155. |
based on experimental data, acsl6 was underexpressed in iso-induced cardiac hypertrophy mouse model and isoproterenol (iso)-induced cardiomyocyte hypertrophy cell model. |
2022-08-17 |
2023-08-14 |
mouse |
| Prabha Burman, Rahul Jaiswal, Kusum Devi, Baisakhi Moharan. Aurintricarboxylic Acid Protects Isoproterenol Induced Left Ventricular Hypertrophy by Modulating TWEAK Signaling. Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology. 2022-08-17. PMID:35977688. |
aurintricarboxylic acid protects isoproterenol induced left ventricular hypertrophy by modulating tweak signaling. |
2022-08-17 |
2023-08-14 |
Not clear |
| Prabha Burman, Rahul Jaiswal, Kusum Devi, Baisakhi Moharan. Aurintricarboxylic Acid Protects Isoproterenol Induced Left Ventricular Hypertrophy by Modulating TWEAK Signaling. Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology. 2022-08-17. PMID:35977688. |
in this study, we investigated the effect of ata on isoproterenol (iso)-induced pathological cardiac hypertrophy. |
2022-08-17 |
2023-08-14 |
Not clear |
| Jian Wang, Yucheng An, Jun Lin, Gang Tan. MicroRNA-194 inhibits isoproterenol-induced chronic cardiac hypertrophy via targeting CnA/NFATc2 signaling in H9c2 cells. Annals of translational medicine. vol 10. issue 14. 2022-08-15. PMID:35965805. |
this study explored the effects of microrna(mir)-194 on chronic cardiac hypertrophy (ch) induced by isoproterenol (iso). |
2022-08-15 |
2023-08-14 |
rat |
| Zhi-Rong Lin, Zhen-Zhen Li, Yan-Jun Cao, Wen-Jing Yu, Jian-Tao Ye, Pei-Qing Li. GDH promotes isoprenaline-induced cardiac hypertrophy by activating mTOR signaling via elevation of α-ketoglutarate level. Naunyn-Schmiedeberg's archives of pharmacology. 2022-07-29. PMID:35904584. |
in the present work, we provide the first evidence that glutamate dehydrogenase (gdh), an enzyme that catalyzes conversion of glutamate into ɑ-ketoglutarate (akg), participates in isoprenaline (iso)-induced cardiac hypertrophy through activating mammalian target of rapamycin (mtor) signaling. |
2022-07-29 |
2023-08-14 |
rat |
| Farogh Ahsan, Tarique Mahmood, Tanveer A Wani, Seema Zargar, Mohammed Haris Siddiqui, Shazia Usmani, Arshiya Shamim, Muhammad Wahajuddi. Effectual Endeavors of Silk Protein Sericin against Isoproterenol Induced Cardiac Toxicity and Hypertrophy in Wistar Rats. Life (Basel, Switzerland). vol 12. issue 7. 2022-07-27. PMID:35888151. |
effectual endeavors of silk protein sericin against isoproterenol induced cardiac toxicity and hypertrophy in wistar rats. |
2022-07-27 |
2023-08-14 |
rat |
| Zhirong Lin, Zhenzhen Li, Zhen Guo, Yanjun Cao, Jingyan Li, Peiqing Liu, Zhuoming L. Epigenetic Reader Bromodomain Containing Protein 2 Facilitates Pathological Cardiac Hypertrophy Frontiers in pharmacology. vol 13. 2022-06-13. PMID:35694272. |
brd2 expression was elevated in cardiac hypertrophy induced by β-adrenergic agonist isoprenaline (iso) |
2022-06-13 |
2023-08-14 |
Not clear |
| Zhenhuan Chen, Haiwen Zhou, Xiantao Huang, Shaoyun Wang, Xiaochao Ouyang, Yunxia Wang, Qianqiang Cao, Liu Yang, Yu Tao, Hengli La. Pirfenidone attenuates cardiac hypertrophy against isoproterenol by inhibiting activation of the janus tyrosine kinase-2/signal transducer and activator of transcription 3 (JAK-2/STAT3) signaling pathway. Bioengineered. vol 13. issue 5. 2022-05-24. PMID:35609321. |
pirfenidone attenuates cardiac hypertrophy against isoproterenol by inhibiting activation of the janus tyrosine kinase-2/signal transducer and activator of transcription 3 (jak-2/stat3) signaling pathway. |
2022-05-24 |
2023-08-13 |
mouse |
| Xi Zheng, Fuxiang Su, Ze Kang, Jingyuan Li, Chenyang Zhang, Yujia Zhang, Liying Ha. Analysis of Therapeutic Targets of A Novel Peptide Athycaltide-1 in the Treatment of Isoproterenol-Induced Pathological Myocardial Hypertrophy. Cardiovascular therapeutics. vol 2022. 2022-05-23. PMID:35599721. |
this study is aimed at identifying the differentially expressed proteins (deps) in myocardial hypertrophy rats induced by isoprenaline (iso) and treated with novel peptide athycaltide-1 (ath-1) and exploring the mechanism of its improvement. |
2022-05-23 |
2023-08-13 |
rat |
| Jacob Russell, Chastidy Bailey, Scott Brown, Vincent G DeMarco, Srinivas Mummidi, Shawn B Bender, Bysani Chandraseka. Minocycline Blunts Isoproterenol-Induced Cardiac Hypertrophy. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35556049. |
here we investigated whether chronic administration of isoproterenol (iso), a β-ar agonist, would promote hypertrophy, fibrosis, and dysfunction, and whether these maladaptive changes are prevented by minocycline, an fda-approved antibiotic, that has been shown to have cardioprotective effects outside of its antibacterial properties. |
2022-05-13 |
2023-08-13 |
Not clear |
| Suxia Guo, Yanhua Yang, Weichun Qian, Yongzhao Yao, Guoxiang Zhou, Lihan Shen, Jianping Zho. MicroRNA-384-5p protects against cardiac hypertrophy via the ALPK3 signaling pathway. Journal of biochemical and molecular toxicology. 2022-05-05. PMID:35510648. |
in this study, cardiac hypertrophy models were constructed using isoproterenol (iso)-/angiotensin-ii (ang-ii) to explore the role of mir-384-5p in cardiac hypertrophy and its molecular mechanism in vivo and in vitro. |
2022-05-05 |
2023-08-13 |
Not clear |
| Chunmei Bai, Qianqian Ma, Qi Li, Lijun Yu, Dong Zhen, Mingjie Liu, Chengxi We. Combination of 1,8-cineole and beta-caryophyllene synergistically reverses cardiac hypertrophy in isoprenaline-induced mice and H9c2 cells. Bioorganic chemistry. vol 124. 2022-04-30. PMID:35489272. |
in the present study, possible drug combinations were screened and the mechanism of the combinations against cardiac hypertrophy was examined within 1,8-cineole, β-caryophyllene, linalool, and β-pinene.h9c2 cells were treatment with 1,8-cineole, β-caryophyllene, linalool, and β-pinene individually or in combination for 24 h after isoprenaline stimulation. |
2022-04-30 |
2023-08-13 |
mouse |
| S Shervin Prince, P Stanely Mainzen Prince, V M Berlin Grac. Valencene post-treatment exhibits cardioprotection via inhibiting cardiac hypertrophy, oxidative stress, nuclear factor- κB inflammatory pathway, and myocardial infarct size in isoproterenol-induced myocardial infarcted rats; A molecular study. European journal of pharmacology. 2022-04-26. PMID:35469837. |
rats were induced mi by isoproterenol (100 mg/kg body weight) and then treated with valencene and cardiac sensitive markers, cardiac hypertrophy, oxidative stress, markers of inflammation, nuclear factor- κb inflammatory pathway, and myocardial infarct size was estimated/determined. |
2022-04-26 |
2023-08-13 |
rat |
| S Shervin Prince, P Stanely Mainzen Prince, V M Berlin Grac. Valencene post-treatment exhibits cardioprotection via inhibiting cardiac hypertrophy, oxidative stress, nuclear factor- κB inflammatory pathway, and myocardial infarct size in isoproterenol-induced myocardial infarcted rats; A molecular study. European journal of pharmacology. 2022-04-26. PMID:35469837. |
the serum cardiac diagnostic markers, cardiac hypertrophy, conjugated dienes, markers of inflammation, pro-inflammatory cytokines, and myocardial infarct size were significantly (p < 0.05) increased by isoproterenol. |
2022-04-26 |
2023-08-13 |
rat |
| Deanna L Muehleman, Claudia Crocini, Alison R Swearingen, Christopher D Ozeroff, Leslie A Leinwan. Regression from pathological hypertrophy in mice is sexually dimorphic and stimulus-specific. American journal of physiology. Heart and circulatory physiology. 2022-03-18. PMID:35302880. |
two pathological stimuli causing hypertrophy via distinct pathways were administered to male and female mice: angiotensin ii [ang ii] or isoproterenol [iso]. |
2022-03-18 |
2023-08-13 |
mouse |
| Ritu Kumari, Aleepta Guha Ray, Dibyanti Mukherjee, Vivek Chander, Dipak Kar, Uppulapu Shravan Kumar, Deepak Bharadwaj P V P, Sanjay K Banerjee, Aditya Konar, Arun Bandyopadhya. Downregulation of PTEN Promotes Autophagy Frontiers in cardiovascular medicine. vol 9. 2022-02-28. PMID:35224041. |
to assess the role of ppar α in chronic hypertrophy, isoproterenol, a β-adrenergic receptor agonist was administered in ppar α knock out (ppar α |
2022-02-28 |
2023-08-13 |
Not clear |