| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shuang-Ling Li, Shun Wang, Yuan He, Di Zheng, Jian Lyu, Ning-Ning Guo, Ying-Ying Guo, Li-Li Li, Ming-Xia Fan, Zhi-Hua Wan. Mouse strain-specific responses of mitochondrial respiratory function and cardiac hypertrophy to isoproterenol treatment. Sheng li xue bao : [Acta physiologica Sinica]. vol 73. issue 3. 2021-07-08. PMID:34230947. |
mouse strain-specific responses of mitochondrial respiratory function and cardiac hypertrophy to isoproterenol treatment. |
2021-07-08 |
2023-08-13 |
mouse |
| Shuang-Ling Li, Shun Wang, Yuan He, Di Zheng, Jian Lyu, Ning-Ning Guo, Ying-Ying Guo, Li-Li Li, Ming-Xia Fan, Zhi-Hua Wan. Mouse strain-specific responses of mitochondrial respiratory function and cardiac hypertrophy to isoproterenol treatment. Sheng li xue bao : [Acta physiologica Sinica]. vol 73. issue 3. 2021-07-08. PMID:34230947. |
two mouse strains, a/j and fvb/nj, were treated with isoproterenol (iso) by osmotic pump to induce cardiac hypertrophy. |
2021-07-08 |
2023-08-13 |
mouse |
| Yu Zhao, Wei-Wei Jia, San Ren, Wei Xiao, Guang-Wei Li, Li Jin, Yan Li. Difluoromethylornithine attenuates isoproterenol-induced cardiac hypertrophy by regulating apoptosis, autophagy and the mitochondria-associated membranes pathway. Experimental and therapeutic medicine. vol 22. issue 2. 2021-07-02. PMID:34194548. |
cardiac hypertrophy was induced in male rats by intravenous administration of isoproterenol (iso; 5 mg/kg/day) for 1, 3,7 and 14 days. |
2021-07-02 |
2023-08-13 |
rat |
| Xiaoying Zhang, Zhiying Zhang, Pengxiang Wang, Yiwei Han, Lijun Liu, Jie Li, Yichun Chen, Duxia Liu, Jinying Wang, Xiaoying Tian, Qin Zhao, Fengxia Ya. Bawei Chenxiang Wan Ameliorates Cardiac Hypertrophy by Activating AMPK/PPAR-α Signaling Pathway Improving Energy Metabolism. Frontiers in pharmacology. vol 12. 2021-06-22. PMID:34149410. |
the dose of 0.2, 0.4, and 0.8 g/kg bcw treated cardiac hypertrophy in sd rat model induced by isoprenaline (iso). |
2021-06-22 |
2023-08-13 |
rat |
| Ganesh Kumar Raut, Sairam Manchineela, Moumita Chakrabarti, Chaitanya Kumar Bhukya, Raju Naini, A Venkateshwari, V D Reddy, Jolly Janette Mendonza, Y Suresh, Pratibha Nallari, Manika Pal Bhadr. Imine stilbene analog ameliorate isoproterenol-induced cardiac hypertrophy and hydrogen peroxide-induced apoptosis. Free radical biology & medicine. vol 153. 2021-06-18. PMID:32311492. |
interestingly one of the analog, compound 3e (10 μm) alleviated isoproterenol (iso, 25 μm) induced hypertrophy in rat cardiomyocyte (h9c2) cells by showing a marked decrease in the myocyte size. |
2021-06-18 |
2023-08-13 |
rat |
| Zhenzhen Li, Zhen Guo, Rui Lan, Sidong Cai, Zhirong Lin, Jingyan Li, Junjian Wang, Zhuoming Li, Peiqing Li. The poly(ADP-ribosyl)ation of BRD4 mediated by PARP1 promoted pathological cardiac hypertrophy. Acta pharmaceutica Sinica. B. vol 11. issue 5. 2021-06-08. PMID:34094834. |
brd4 silencing or bet inhibitors jq1 and ms417 prevented cardiac hypertrophic responses induced by isoproterenol (iso), whereas overexpression of brd4 promoted cardiac hypertrophy, confirming the critical role of brd4 in pathological cardiac hypertrophy. |
2021-06-08 |
2023-08-13 |
Not clear |
| Ying Mei, Bo Liu, Hao Su, Hao Zhang, Fei Liu, Qingjin Ke, Xiaoou Sun, Wen Ta. Isosteviol sodium protects the cardiomyocyte response associated with the SIRT1/PGC-1α pathway. Journal of cellular and molecular medicine. vol 24. issue 18. 2021-06-03. PMID:32757458. |
we established two myocardial hypertrophy models by treating h9c2 cells with high glucose (hg) and isoprenaline (iso). |
2021-06-03 |
2023-08-13 |
Not clear |
| Tao-Li Sun, Wen-Qun Li, Xiao-Liang Tong, Xin-Yi Liu, Wen-Hu Zho. Xanthohumol attenuates isoprenaline-induced cardiac hypertrophy and fibrosis through regulating PTEN/AKT/mTOR pathway. European journal of pharmacology. vol 891. 2021-05-20. PMID:33127362. |
present study aimed to investigate the protective role of xn against isoprenaline (iso)-induced cardiac hypertrophy and fibrosis, and elucidate the underlying mechanism. |
2021-05-20 |
2023-08-13 |
mouse |
| Prema Velusamy, Thangarajeswari Mohan, Divya Bhavani Ravi, S N Kishore Kumar, Ashokkumar Srinivasan, Lakshmi Narasimhan Chakrapani, Abhilasha Singh, Saradhadevi Varadharaj, Periandavan Kalaiselv. Targeting the Nrf2/ARE Signalling Pathway to Mitigate Isoproterenol-Induced Cardiac Hypertrophy: Plausible Role of Hesperetin in Redox Homeostasis. Oxidative medicine and cellular longevity. vol 2020. 2021-05-14. PMID:32952852. |
a cardiac hypertrophy model was established with subcutaneous injection of isoproterenol in male wistar rats. |
2021-05-14 |
2023-08-13 |
rat |
| Anna Pędzińska-Betiuk, Jolanta Weresa, Eberhard Schlicker, Ewa Harasim-Symbor, Marek Toczek, Irena Kasacka, Bernadetta Gajo, Barbara Malinowsk. Chronic cannabidiol treatment reduces the carbachol-induced coronary constriction and left ventricular cardiomyocyte width of the isolated hypertensive rat heart. Toxicology and applied pharmacology. vol 411. 2021-05-11. PMID:33338514. |
however, it failed to affect left ventricular hypertrophy and even aggravated the impaired positive and negative lusitropic effects elicited by isoprenaline and carbachol, respectively. |
2021-05-11 |
2023-08-13 |
rat |
| b' Sevgi \\xc5\\x9eeng\\xc3\\xbcl Ayan, Ahmet K S\\xc4\\xb1rcan, Mohamedou Abewa, Ahmet Kurt, U\\xc4\\x9fur Dalaman, Nazmi Yara\\xc5\\x9. Mathematical model of the ventricular action potential and effects of isoproterenol-induced cardiac hypertrophy in rats. European biophysics journal : EBJ. vol 49. issue 5. 2021-04-30. PMID:32462262.' |
in particular, changes in ap mechanisms in the isoproterenol (iso) -induced hypertrophic heart model are incompletely understood. |
2021-04-30 |
2023-08-13 |
rat |
| J Roque-Jorge, S Hernández-Gutiérrez, G Díaz-Rosas, A J García-Chequer, A López-Torres, A Contreras-Ramo. Data on sodium tetraborate as a modulation of hypertrophic intracellular signals. Data in brief. vol 35. 2021-04-16. PMID:33850976. |
this article also indicates the data on the optimal concentration of isoproterenol as an inducer of hypertrophy in cardiomyocytes. |
2021-04-16 |
2023-08-13 |
Not clear |
| Weinian Gao, Na Guo, Shuguang Zhao, Ziying Chen, Wenli Zhang, Fang Yan, Hongjuan Liao, Kui Ch. Carboxypeptidase A4 promotes cardiomyocyte hypertrophy through activating PI3K-AKT-mTOR signaling. Bioscience reports. vol 40. issue 5. 2021-03-23. PMID:32347291. |
the expression of cpa4 was significantly increased in the hypertrophic heart tissues of human patients and isoproterenol (iso)-induced hypertrophic heart tissues of mice. |
2021-03-23 |
2023-08-13 |
mouse |
| Fatima Saqib, Khizra Mujahid, Muhammad Arif Aslam, Alotaibi Modhi, Marius Alexandru Moga, Elena Bobescu, Luigi Marcean. Ex vivo and in vivo studies of Viola tricolor Linn. as potential cardio protective and hypotensive agent: Inhibition of voltage-gated Ca FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 34. issue 7. 2021-03-04. PMID:32475023. |
isoproterenol was employed for acute myocardial infarction (ami) and left ventricular hypertrophy (lvh) development and cardioprotective effects of vt.cr were evaluated hemodynamically and histopathologically. |
2021-03-04 |
2023-08-13 |
rat |
| Ali Khalilimeybodi, Alexander M Paap, Steven L M Christiansen, Jeffrey J Saucerma. Context-specific network modeling identifies new crosstalk in β-adrenergic cardiac hypertrophy. PLoS computational biology. vol 16. issue 12. 2021-02-19. PMID:33338038. |
applying this pipeline to our prior-knowledge hypertrophy network with context-specific data revealed key signaling reactions which distinctly regulate cell response to isoproterenol, phenylephrine, angiotensin ii and stretch. |
2021-02-19 |
2023-08-13 |
Not clear |
| Xiaojun Feng, Yanan Wang, Wenxu Chen, Suowen Xu, Lingli Li, Yadi Geng, Aizong Shen, Hui Gao, Lei Zhang, Sheng Li. SIRT3 inhibits cardiac hypertrophy by regulating PARP-1 activity. Aging. vol 12. issue 5. 2021-02-18. PMID:32139662. |
moreover, overexpression of sirt3 by adenovirus inhibited the expression of cardiac hypertrophic genes-anf and bnp, as well as abrogating parp-1 activation induced by isoproterenol or phenylephrine. |
2021-02-18 |
2023-08-13 |
Not clear |
| Kun Miao, Ling Zhou, Hongping Ba, Chenxi Li, Haiyan Gu, Bingjiao Yin, Jing Wang, Xiang-Ping Yang, Zhuoya Li, Dao Wen Wan. Transmembrane tumor necrosis factor alpha attenuates pressure-overload cardiac hypertrophy via tumor necrosis factor receptor 2. PLoS biology. vol 18. issue 12. 2021-02-02. PMID:33270628. |
herein, we found that tnf receptor 1 (tnfr1) knockout (ko) or knockdown (kd) by short hairpin rna or small interfering rna (sirna) significantly alleviated cardiac hypertrophy, heart dysfunction, fibrosis, and inflammation with increased tmtnf-α expression, whereas tnfr2 ko or kd exacerbated the pathological phenomena with increased stnf-α secretion in transverse aortic constriction (tac)- and isoproterenol (iso)-induced cardiac hypertrophy in vivo and in vitro, respectively, indicating the beneficial effects of tnfr2 associated with tmtnf-α. |
2021-02-02 |
2023-08-13 |
Not clear |
| Ming-Hui Yang, Hao Wang, Sheng-Na Han, Xin Jia, Si Zhang, Fei-Fei Dai, Meng-Jiao Zhou, Zhongnan Yin, Tian-Qi Wang, Ming-Xi Zang, Li-Xiang Xu. Circular RNA expression in isoproterenol hydrochloride-induced cardiac hypertrophy. Aging. vol 12. issue 3. 2021-01-19. PMID:32023551. |
circular rna expression in isoproterenol hydrochloride-induced cardiac hypertrophy. |
2021-01-19 |
2023-08-13 |
mouse |
| Ming-Hui Yang, Hao Wang, Sheng-Na Han, Xin Jia, Si Zhang, Fei-Fei Dai, Meng-Jiao Zhou, Zhongnan Yin, Tian-Qi Wang, Ming-Xi Zang, Li-Xiang Xu. Circular RNA expression in isoproterenol hydrochloride-induced cardiac hypertrophy. Aging. vol 12. issue 3. 2021-01-19. PMID:32023551. |
by circrna sequencing in left ventricular specimens collected from 8-week-old mice with isoproterenol hydrochloride-induced cardiac hypertrophy, we found 401 out of 3323 total circrnas were dysregulated in the hypertrophic hearts compared with the controls. |
2021-01-19 |
2023-08-13 |
mouse |
| Sara S Nunes, Nicole Feric, Aric Pahnke, Jason W Miklas, Mark Li, John Coles, Mark Gagliardi, Gordon Keller, Milica Radisi. Human Stem Cell-Derived Cardiac Model of Chronic Drug Exposure. ACS biomaterials science & engineering. vol 3. issue 9. 2021-01-14. PMID:33440549. |
this demonstrates that human biowires treated for 7 days with isoproterenol, angiotensin ii, or endothelin-1 exhibit some changes compatible with hypertrophic cardiomyopathy. |
2021-01-14 |
2023-08-13 |
human |