| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Weinian Gao, Na Guo, Shuguang Zhao, Ziying Chen, Wenli Zhang, Fang Yan, Hongjuan Liao, Kui Ch. HTR2A promotes the development of cardiac hypertrophy by activating PI3K-PDK1-AKT-mTOR signaling. Cell stress & chaperones. vol 25. issue 6. 2021-09-21. PMID:32519137. |
besides, the expression of htr2a was also upregulated in isoproterenol (iso)-induced cardiac hypertrophy in the mouse. |
2021-09-21 |
2023-08-13 |
mouse |
| Mi Tian, Xiuxin Jiang, Xinyun Li, Jianmin Yang, Cheng Zhang, Wencheng Zhan. LKB1IP promotes pathological cardiac hypertrophy by targeting PTEN/Akt signalling pathway. Journal of cellular and molecular medicine. vol 25. issue 5. 2021-09-21. PMID:33486894. |
we investigated the cardiac level of lkb1ip in samples from patients with heart failure and mice with cardiac hypertrophy induced by isoproterenol (iso) or transverse aortic constriction (tac). |
2021-09-21 |
2023-08-13 |
mouse |
| Yao Xu, Chen Liang, Ying Luo, Tongcun Zhan. MBNL1 regulates isoproterenol-induced myocardial remodelling in vitro and in vivo. Journal of cellular and molecular medicine. vol 25. issue 2. 2021-09-14. PMID:33295096. |
in this study, we observed the high expression of mbnl1 in cardiac tissue and peripheral blood of an isoproterenol (iso)-induced cardiac hypertrophy mouse model. |
2021-09-14 |
2023-08-13 |
mouse |
| Nanqi Cui, Takayuki Sakurai, Akiko Kamiyoshi, Yuka Ichikawa-Shindo, Hisaka Kawate, Megumu Tanaka, Masaaki Tanaka, Yangxuan Wei, Shinji Kakihara, Yunlu Zhao, Kohsuke Aruga, Hiroyuki Kawagishi, Tsutomu Nakada, Mitsuhiko Yamada, Takayuki Shind. Adrenomedullin-RAMP2 and -RAMP3 Systems Regulate Cardiac Homeostasis during Cardiovascular Stress. Endocrinology. vol 162. issue 3. 2021-09-10. PMID:33545715. |
exposing c-ramp2-/- cardiomyocytes to isoproterenol enhanced their hypertrophy and oxidative stress compared with wild-type cells. |
2021-09-10 |
2023-08-13 |
mouse |
| S Hernández-Gutiérrez, J Roque-Jorge, A López-Torres, G Díaz-Rosas, A J García-Chequer, A Contreras-Ramo. Role of sodium tetraborate as a cardioprotective or competitive agent: Modulation of hypertrophic intracellular signals. Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS). vol 62. 2021-08-19. PMID:32563862. |
however, sodium tetraborate attenuates isoproterenol induced hypertrophy damage in cardiomyocytes when these two compounds are added simultaneously. |
2021-08-19 |
2023-08-13 |
Not clear |
| Dharaniyambigai Kuberapandian, Victor Arokia Dos. Identification of serum predictors of n-acetyl-l-cysteine and isoproterenol induced remodelling in cardiac hypertrophy. Turkish journal of biology = Turk biyoloji dergisi. vol 45. issue 3. 2021-08-12. PMID:34377056. |
identification of serum predictors of n-acetyl-l-cysteine and isoproterenol induced remodelling in cardiac hypertrophy. |
2021-08-12 |
2023-08-13 |
rat |
| Jiantao Qiu, Huaiteng Xiao, Shunchang Zhou, Weimin Du, Xiang Mu, Guangjun Shi, Xueying Ta. Bone marrow mesenchymal stem cells inhibit cardiac hypertrophy by enhancing FoxO1 transcription. Cell biology international. vol 45. issue 1. 2021-08-11. PMID:33049085. |
we induced cardiomyocyte hypertrophy in cultured rat cells through isoproterenol (iso) treatment with or without bmsc coculture. |
2021-08-11 |
2023-08-13 |
rat |
| Hongfei Xu, Zhen Wang, Miao Chen, Wenting Zhao, Tingting Tao, Liang Ma, Yiming Ni, Weidong L. YTHDF2 alleviates cardiac hypertrophy via regulating Myh7 mRNA decoy. Cell & bioscience. vol 11. issue 1. 2021-07-18. PMID:34266473. |
primary cardiomyocytes were isolated and stimulated with isoproterenol (iso) or phenylephrine (phe) to induce myocardial hypertrophy. |
2021-07-18 |
2023-08-13 |
mouse |
| Shuang-Ling Li, Shun Wang, Yuan He, Di Zheng, Jian Lyu, Ning-Ning Guo, Ying-Ying Guo, Li-Li Li, Ming-Xia Fan, Zhi-Hua Wan. Mouse strain-specific responses of mitochondrial respiratory function and cardiac hypertrophy to isoproterenol treatment. Sheng li xue bao : [Acta physiologica Sinica]. vol 73. issue 3. 2021-07-08. PMID:34230947. |
mouse strain-specific responses of mitochondrial respiratory function and cardiac hypertrophy to isoproterenol treatment. |
2021-07-08 |
2023-08-13 |
mouse |
| Shuang-Ling Li, Shun Wang, Yuan He, Di Zheng, Jian Lyu, Ning-Ning Guo, Ying-Ying Guo, Li-Li Li, Ming-Xia Fan, Zhi-Hua Wan. Mouse strain-specific responses of mitochondrial respiratory function and cardiac hypertrophy to isoproterenol treatment. Sheng li xue bao : [Acta physiologica Sinica]. vol 73. issue 3. 2021-07-08. PMID:34230947. |
two mouse strains, a/j and fvb/nj, were treated with isoproterenol (iso) by osmotic pump to induce cardiac hypertrophy. |
2021-07-08 |
2023-08-13 |
mouse |
| Yu Zhao, Wei-Wei Jia, San Ren, Wei Xiao, Guang-Wei Li, Li Jin, Yan Li. Difluoromethylornithine attenuates isoproterenol-induced cardiac hypertrophy by regulating apoptosis, autophagy and the mitochondria-associated membranes pathway. Experimental and therapeutic medicine. vol 22. issue 2. 2021-07-02. PMID:34194548. |
cardiac hypertrophy was induced in male rats by intravenous administration of isoproterenol (iso; 5 mg/kg/day) for 1, 3,7 and 14 days. |
2021-07-02 |
2023-08-13 |
rat |
| Xiaoying Zhang, Zhiying Zhang, Pengxiang Wang, Yiwei Han, Lijun Liu, Jie Li, Yichun Chen, Duxia Liu, Jinying Wang, Xiaoying Tian, Qin Zhao, Fengxia Ya. Bawei Chenxiang Wan Ameliorates Cardiac Hypertrophy by Activating AMPK/PPAR-α Signaling Pathway Improving Energy Metabolism. Frontiers in pharmacology. vol 12. 2021-06-22. PMID:34149410. |
the dose of 0.2, 0.4, and 0.8 g/kg bcw treated cardiac hypertrophy in sd rat model induced by isoprenaline (iso). |
2021-06-22 |
2023-08-13 |
rat |
| Ganesh Kumar Raut, Sairam Manchineela, Moumita Chakrabarti, Chaitanya Kumar Bhukya, Raju Naini, A Venkateshwari, V D Reddy, Jolly Janette Mendonza, Y Suresh, Pratibha Nallari, Manika Pal Bhadr. Imine stilbene analog ameliorate isoproterenol-induced cardiac hypertrophy and hydrogen peroxide-induced apoptosis. Free radical biology & medicine. vol 153. 2021-06-18. PMID:32311492. |
interestingly one of the analog, compound 3e (10 μm) alleviated isoproterenol (iso, 25 μm) induced hypertrophy in rat cardiomyocyte (h9c2) cells by showing a marked decrease in the myocyte size. |
2021-06-18 |
2023-08-13 |
rat |
| Zhenzhen Li, Zhen Guo, Rui Lan, Sidong Cai, Zhirong Lin, Jingyan Li, Junjian Wang, Zhuoming Li, Peiqing Li. The poly(ADP-ribosyl)ation of BRD4 mediated by PARP1 promoted pathological cardiac hypertrophy. Acta pharmaceutica Sinica. B. vol 11. issue 5. 2021-06-08. PMID:34094834. |
brd4 silencing or bet inhibitors jq1 and ms417 prevented cardiac hypertrophic responses induced by isoproterenol (iso), whereas overexpression of brd4 promoted cardiac hypertrophy, confirming the critical role of brd4 in pathological cardiac hypertrophy. |
2021-06-08 |
2023-08-13 |
Not clear |
| Ying Mei, Bo Liu, Hao Su, Hao Zhang, Fei Liu, Qingjin Ke, Xiaoou Sun, Wen Ta. Isosteviol sodium protects the cardiomyocyte response associated with the SIRT1/PGC-1α pathway. Journal of cellular and molecular medicine. vol 24. issue 18. 2021-06-03. PMID:32757458. |
we established two myocardial hypertrophy models by treating h9c2 cells with high glucose (hg) and isoprenaline (iso). |
2021-06-03 |
2023-08-13 |
Not clear |
| Tao-Li Sun, Wen-Qun Li, Xiao-Liang Tong, Xin-Yi Liu, Wen-Hu Zho. Xanthohumol attenuates isoprenaline-induced cardiac hypertrophy and fibrosis through regulating PTEN/AKT/mTOR pathway. European journal of pharmacology. vol 891. 2021-05-20. PMID:33127362. |
present study aimed to investigate the protective role of xn against isoprenaline (iso)-induced cardiac hypertrophy and fibrosis, and elucidate the underlying mechanism. |
2021-05-20 |
2023-08-13 |
mouse |
| Prema Velusamy, Thangarajeswari Mohan, Divya Bhavani Ravi, S N Kishore Kumar, Ashokkumar Srinivasan, Lakshmi Narasimhan Chakrapani, Abhilasha Singh, Saradhadevi Varadharaj, Periandavan Kalaiselv. Targeting the Nrf2/ARE Signalling Pathway to Mitigate Isoproterenol-Induced Cardiac Hypertrophy: Plausible Role of Hesperetin in Redox Homeostasis. Oxidative medicine and cellular longevity. vol 2020. 2021-05-14. PMID:32952852. |
a cardiac hypertrophy model was established with subcutaneous injection of isoproterenol in male wistar rats. |
2021-05-14 |
2023-08-13 |
rat |
| Anna Pędzińska-Betiuk, Jolanta Weresa, Eberhard Schlicker, Ewa Harasim-Symbor, Marek Toczek, Irena Kasacka, Bernadetta Gajo, Barbara Malinowsk. Chronic cannabidiol treatment reduces the carbachol-induced coronary constriction and left ventricular cardiomyocyte width of the isolated hypertensive rat heart. Toxicology and applied pharmacology. vol 411. 2021-05-11. PMID:33338514. |
however, it failed to affect left ventricular hypertrophy and even aggravated the impaired positive and negative lusitropic effects elicited by isoprenaline and carbachol, respectively. |
2021-05-11 |
2023-08-13 |
rat |
| b' Sevgi \\xc5\\x9eeng\\xc3\\xbcl Ayan, Ahmet K S\\xc4\\xb1rcan, Mohamedou Abewa, Ahmet Kurt, U\\xc4\\x9fur Dalaman, Nazmi Yara\\xc5\\x9. Mathematical model of the ventricular action potential and effects of isoproterenol-induced cardiac hypertrophy in rats. European biophysics journal : EBJ. vol 49. issue 5. 2021-04-30. PMID:32462262.' |
in particular, changes in ap mechanisms in the isoproterenol (iso) -induced hypertrophic heart model are incompletely understood. |
2021-04-30 |
2023-08-13 |
rat |
| J Roque-Jorge, S Hernández-Gutiérrez, G Díaz-Rosas, A J García-Chequer, A López-Torres, A Contreras-Ramo. Data on sodium tetraborate as a modulation of hypertrophic intracellular signals. Data in brief. vol 35. 2021-04-16. PMID:33850976. |
this article also indicates the data on the optimal concentration of isoproterenol as an inducer of hypertrophy in cardiomyocytes. |
2021-04-16 |
2023-08-13 |
Not clear |