| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Nasiruddin Nalban, Rajendra Sangaraju, Sateesh Alavala, Salma Mukhtar Mir, Mahesh Kumar Jerald, Ramakrishna Sistl. Arbutin Attenuates Isoproterenol-Induced Cardiac Hypertrophy by Inhibiting TLR-4/NF-κB Pathway in Mice. Cardiovascular toxicology. vol 20. issue 3. 2020-09-28. PMID:31485892. |
the study aims to understand the effect of arbutin on isoproterenol (iso)-induced cardiac hypertrophy in mice. |
2020-09-28 |
2023-08-13 |
mouse |
| Marianne K O Grant, Ibrahim Y Abdelgawad, Christine A Lewis, Davis Seelig, Beshay N Zordok. Lack of sexual dimorphism in a mouse model of isoproterenol-induced cardiac dysfunction. PloS one. vol 15. issue 7. 2020-09-10. PMID:32645007. |
similarly, prolonged isoproterenol administration induced hypertrophic and fibrotic genes in hearts of male and female mice to the same extent. |
2020-09-10 |
2023-08-13 |
mouse |
| S-S Song, G Tang, L-X Tang, L-Y Si, W Xion. NAKα2 inhibits fibrosis formation and protects against cardiomyocyte hypertrophy by suppressing hypertrophy associated molecules and activating LTCC/NCX signaling pathway. European review for medical and pharmacological sciences. vol 23. issue 7. 2020-09-08. PMID:31002153. |
this study aimed to evaluate effects of na+/k+ aptaseα2 (nakα2) on isoprenaline (iso) induced cardiomyocyte hypertrophy. |
2020-09-08 |
2023-08-13 |
Not clear |
| Lihua Qi, Xiaochun Chi, Xi Zhang, Xueqian Feng, Wenhui Chu, Shengchang Zhang, Junzhou Wu, Yao Song, Youyi Zhang, Wei Kong, Yu Yu, Hongquan Zhan. Kindlin-2 suppresses transcription factor GATA4 through interaction with SUV39H1 to attenuate hypertrophy. Cell death & disease. vol 10. issue 12. 2020-08-31. PMID:31767831. |
we found that kindlin-2 suppresses the expression of gata4 through binding to its promoter and prevents cardiomyocytes from hypertrophy induced by isoproterenol (iso) treatment. |
2020-08-31 |
2023-08-13 |
mouse |
| Toru Miyoshi, Kazufumi Nakamura, Daiji Miura, Masashi Yoshida, Yukihiro Saito, Satoshi Akagi, Yuko Ohno, Megumi Kondo, Hiroshi It. Effect of LCZ696, a dual angiotensin receptor neprilysin inhibitor, on isoproterenol-induced cardiac hypertrophy, fibrosis, and hemodynamic change in rats. Cardiology journal. vol 26. issue 5. 2020-07-28. PMID:29718530. |
this study evaluated whether lcz696 affects left ventricular hypertrophy, fibrosis, and hemodynamics in isoproterenol (iso)-treated rats compared with valsartan alone. |
2020-07-28 |
2023-08-13 |
rat |
| Yaoxu Chen, Huimin Beng, Hao Su, Fuping Han, Zhuo Fan, Nanying Lv, Aleksandar Jovanović, Wen Ta. Isosteviol prevents the development of isoprenaline‑induced myocardial hypertrophy. International journal of molecular medicine. vol 44. issue 5. 2020-07-27. PMID:31545484. |
in the current study, whether stvna interferes with the development of cardiac hypertrophy, which is induced by isoprenaline (iso), was investigated in an experimental rat model. |
2020-07-27 |
2023-08-13 |
rat |
| Si Zhang, Zhongnan Yin, Fei-Fei Dai, Hao Wang, Meng-Jiao Zhou, Ming-Hui Yang, Shu-Feng Zhang, Zhi-Feng Fu, Ying-Wu Mei, Ming-Xi Zang, Lixiang Xu. miR-29a attenuates cardiac hypertrophy through inhibition of PPARδ expression. Journal of cellular physiology. vol 234. issue 8. 2020-05-08. PMID:30580435. |
in addition, we identify a novel role of mir-29a, in which it has a cardioprotective function in isoproterenol hydrochloride-induced cardiac hypertrophy by targeting pparδ and downregulating anf. |
2020-05-08 |
2023-08-13 |
Not clear |
| Si Zhang, Zhongnan Yin, Fei-Fei Dai, Hao Wang, Meng-Jiao Zhou, Ming-Hui Yang, Shu-Feng Zhang, Zhi-Feng Fu, Ying-Wu Mei, Ming-Xi Zang, Lixiang Xu. miR-29a attenuates cardiac hypertrophy through inhibition of PPARδ expression. Journal of cellular physiology. vol 234. issue 8. 2020-05-08. PMID:30580435. |
finally, we provide evidence that mir-29a reduces the isoproterenol hydrochloride-induced cardiac hypertrophy response, thereby underlining the potential clinical relevance of mir-29a in which it may serve as a potent therapeutic target for heart hypertrophy treatment. |
2020-05-08 |
2023-08-13 |
Not clear |
| Isil Ozakc. Antihypertrophic Effects of Nebivolol on Neonatal Cardiomyocyte Hypertrophy Models. Journal of cardiovascular pharmacology. vol 73. issue 3. 2020-05-04. PMID:30601193. |
in the current study, in vitro cardiomyocyte hypertrophy model was induced with isoprenaline (10 μm), angiotensin ii (1 μm), and phenylephrine (20 μm) in neonatal cardiomyocytes isolated from 0- to 2-day-old sprague-dawley rats. |
2020-05-04 |
2023-08-13 |
rat |
| Zhengbo Zhao, Han Liu, Dongmei Gu. Aliskiren attenuates cardiac dysfunction by modulation of the mTOR and apoptosis pathways. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 53. issue 2. 2020-04-07. PMID:31994601. |
a rat model of cardiac hypertrophy was induced by isoproterenol treatment (5 mg·kg-1·day-1) for 4 weeks, with or without als treatment at 20 mg·kg-1·day-1. |
2020-04-07 |
2023-08-13 |
rat |
| Kai-Chun Cheng, Yingxiao Li, Wei-Ting Chang, Zhih-Cherng Chen, Juei-Tang Cheng, Cheng-Chia Tsa. Ubiquitin-protein ligase E3a (UBE3A) as a new biomarker of cardiac hypertrophy in cell models. Journal of food and drug analysis. vol 27. issue 1. 2020-03-23. PMID:30648591. |
the cardiac hypertrophy is induced in rat-derived heart cell line h9c2 cells by potassium bromate (kbro3), high glucose (hg), or isoproterenol (iso), respectively. |
2020-03-23 |
2023-08-13 |
Not clear |
| Stephanie Binas, Maria Knyrim, Julia Hupfeld, Udo Kloeckner, Sindy Rabe, Sigrid Mildenberger, Katja Quarch, Nicole Strätz, Danny Misiak, Michael Gekle, Claudia Grossmann, Barbara Schreie. miR-221 and -222 target CACNA1C and KCNJ5 leading to altered cardiac ion channel expression and current density. Cellular and molecular life sciences : CMLS. vol 77. issue 5. 2020-03-18. PMID:31312877. |
additionally, we evaluated the change of mir-221/222 in vivo in two models of pharmacologically induced heart hypertrophy (angiotensin ii, isoprenaline), thereby demonstrating a stimulus-induced increase in mir-221/222 in vivo by angiotensin ii but not by isoprenaline. |
2020-03-18 |
2023-08-13 |
mouse |
| Yanfei Li, Linlin Ma, Sijie Gu, Jiewen Tian, Yilin Cao, Zi Jin, Jingyi Chen, Bingbing Gu, Jiayin Tu, Zhixiao Wang, Xinming Li, Zhongping Ning, Yueling Ji. UBE3A alleviates isoproterenol-induced cardiac hypertrophy through the inhibition of the TLR4/MMP-9 signaling pathway. Acta biochimica et biophysica Sinica. vol 52. issue 1. 2020-02-26. PMID:31681945. |
in this study, we explored the potential mechanism underlying cardiac hypertrophy induced by isoproterenol. |
2020-02-26 |
2023-08-13 |
Not clear |
| Yanfei Li, Linlin Ma, Sijie Gu, Jiewen Tian, Yilin Cao, Zi Jin, Jingyi Chen, Bingbing Gu, Jiayin Tu, Zhixiao Wang, Xinming Li, Zhongping Ning, Yueling Ji. UBE3A alleviates isoproterenol-induced cardiac hypertrophy through the inhibition of the TLR4/MMP-9 signaling pathway. Acta biochimica et biophysica Sinica. vol 52. issue 1. 2020-02-26. PMID:31681945. |
our results showed that isoproterenol induced cardiac hypertrophy in ac16 cells, as reflected by the increased cell surface area and increased hypertrophic markers, which was accompanied by increased ubiquitin-protein ligase e3a (ube3a) expression. |
2020-02-26 |
2023-08-13 |
Not clear |
| Yanfei Li, Linlin Ma, Sijie Gu, Jiewen Tian, Yilin Cao, Zi Jin, Jingyi Chen, Bingbing Gu, Jiayin Tu, Zhixiao Wang, Xinming Li, Zhongping Ning, Yueling Ji. UBE3A alleviates isoproterenol-induced cardiac hypertrophy through the inhibition of the TLR4/MMP-9 signaling pathway. Acta biochimica et biophysica Sinica. vol 52. issue 1. 2020-02-26. PMID:31681945. |
moreover, ube3a knockdown by sirnas accelerated cardiac hypertrophy, suggesting that increased ube3a expression induced by isoproterenol might be a protective response and ube3a might be a protective factor against cardiac hypertrophy. |
2020-02-26 |
2023-08-13 |
Not clear |
| Harry H Matundan, Jon Sin, Magali Noval Rivas, Michael C Fishbein, Thomas J Lehman, Shuang Chen, Roberta A Gottlieb, Timothy R Crother, Masanori Abe, Moshe Ardit. Myocardial fibrosis after adrenergic stimulation as a long-term sequela in a mouse model of Kawasaki disease vasculitis. JCI insight. vol 4. issue 3. 2020-02-25. PMID:30728329. |
we found that adrenergic stimulation with isoproterenol following lcwe-induced kd vasculitis in mice was associated with increased risk of cardiac hypertrophy and myocardial fibrosis, diminished ejection fraction, and increased serum levels of brain natriuretic peptide. |
2020-02-25 |
2023-08-13 |
mouse |
| Ying-Xu Wu, Jie-Kun Cheng, Le Li, Hou-Quan Ta. [Effects of chrysanthemum flower extract on cardiac hypertrophy induced by isoprenaline in mice]. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology. vol 35. issue 5. 2020-02-24. PMID:31894685. |
[effects of chrysanthemum flower extract on cardiac hypertrophy induced by isoprenaline in mice]. |
2020-02-24 |
2023-08-13 |
mouse |
| Jing-Xia Du, Jian-Zhao Wu, Zhi Li, Cai Zhang, Meng-Ting Shi, Jia Zhao, Man-Wen Jin, Hui Li. Pentamethylquercetin protects against cardiac remodeling via activation of Sestrin2. Biochemical and biophysical research communications. vol 512. issue 2. 2020-02-18. PMID:30898320. |
we generated a transverse aorta constriction (tac)-induced pressure-overload cardiac-remodeling model in mice, and also established an isoproterenol (iso)-induced neonatal rat cardiomyocyte (nrcm) hypertrophy model. |
2020-02-18 |
2023-08-13 |
mouse |
| Isadora Prado Cano, Thiago José Dionisio, Tânia Mary Cestari, Adriana Maria Calvo, Bella Luna Colombini-Ishikiriama, Flávio Augusto Cardoso Faria, Walter Luiz Siqueira, Carlos Ferreira Santo. Losartan and isoproterenol promote alterations in the local renin-angiotensin system of rat salivary glands. PloS one. vol 14. issue 5. 2020-02-03. PMID:31116771. |
isoproterenol treatment affected gene expression profiles in parotid (ace, ace-2, at1-a, mas, agt), and submandibular (ace, at2, agt) glands, thus promoting acinar hypertrophy in serous acini, without significant changes in salivary flow or total protein content. |
2020-02-03 |
2023-08-13 |
rat |
| Xue-Cui Wu, Yun Zhao, Cong Li, Hai-Rong Xiong, Zhi-Wei Zheng, Jun Zhou, Rong Liu, Wei Gong, Chao-Qi Li. [Expression and bioinformatics analysis of miRNA in ISO-induced rat cardiac hypertrophy]. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology. vol 35. issue 5. 2020-01-16. PMID:31894683. |
to investigate the expression changes of mirnas (mir199a-5p, mir206, mir133a-3p, mir499-5p) in rat model of cardiac hypertrophy induced by isoproterenol (iso), and to explore the main signal pathways and molecular mechanisms which related to that with the way of bioinformatics. |
2020-01-16 |
2023-08-13 |
rat |