| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xiao-Chun Xiao, Wei-Hong Chen, Yuan-Yuan Cao, Yong-Jun Lou, Yuan Liu, Jin Wang, Xu-Feng Zhai, Nian-Sheng Li, Ying L. [Protective effect of Dendrobium candidum on isoproterenol induced cardiac hypertrophy in rats]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 43. issue 4. 2019-07-11. PMID:29600658. |
[protective effect of dendrobium candidum on isoproterenol induced cardiac hypertrophy in rats]. |
2019-07-11 |
2023-08-13 |
rat |
| Christoph D Rau, Milagros C Romay, Mary Tuteryan, Jessica J-C Wang, Marc Santolini, Shuxun Ren, Alain Karma, James N Weiss, Yibin Wang, Aldons J Lusi. Systems Genetics Approach Identifies Gene Pathways and Adamts2 as Drivers of Isoproterenol-Induced Cardiac Hypertrophy and Cardiomyopathy in Mice. Cell systems. vol 4. issue 1. 2019-07-01. PMID:27866946. |
we previously reported a genetic analysis of heart failure traits in a population of inbred mouse strains treated with isoproterenol to mimic catecholamine-driven cardiac hypertrophy. |
2019-07-01 |
2023-08-13 |
mouse |
| Linlin Shang, Lv Pin, Shanshan Zhu, Xiaohang Zhong, Yubiao Zhang, Mao Shun, Yunen Liu, Mingxiao Ho. Plantamajoside attenuates isoproterenol-induced cardiac hypertrophy associated with the HDAC2 and AKT/ GSK-3β signaling pathway. Chemico-biological interactions. vol 307. 2019-06-26. PMID:31009642. |
here, we investigated the effects and mechanism of pms on isoproterenol (iso)-induced cardiac hypertrophy. |
2019-06-26 |
2023-08-13 |
Not clear |
| Xinlei Hu, Qiong Ou-Yang, Lanlan Wang, Tingting Li, Xiaoxue Xie, Jun Li. AdipoRon prevents l-thyroxine or isoproterenol-induced cardiac hypertrophy through regulating the AMPK-related pathway. Acta biochimica et biophysica Sinica. vol 51. issue 1. 2019-05-24. PMID:30566571. |
in the present study, we explored whether adiporon attenuates isoprenaline (iso) or l-thyroxine-induced cardiac hypertrophy in sprague-dawley (sd) rats and whether the anti-hypertrophy effect is mediated by ampk-related pathway. |
2019-05-24 |
2023-08-13 |
rat |
| Jia-Shen Li, Xiao-Yu Zhu, Mei-Li Lu, Jun-Hong Gao, Hong-Xin Wang, Xiao-Chun Y. [Effect of Combined Intervention of Electroacupuncture and Astragaloside IV on Myocardial Hypertrophy and TGF-β 1/Smad Signaling in Rats with Myocardial Fibrosis]. Zhen ci yan jiu = Acupuncture research. vol 42. issue 6. 2019-04-03. PMID:29318851. |
to observe the effect of combined intervention of electroacupuncture (ea) and astragaloside iv(asiv) on cardiac hypertrophy and transforming growth factor β 1 (tgf-β 1)/smad signaling in isoproterenol (iso) induced cardiac hypertrophy rats, so as to investigate its underlying mechanisms in improving myocardial fibrosis. |
2019-04-03 |
2023-08-13 |
rat |
| Sumia A Bageghni, Karen E Hemmings, Ngonidzashe Zava, Christopher P Denton, Karen E Porter, Justin F X Ainscough, Mark J Drinkhill, Neil A Turne. Cardiac fibroblast-specific p38α MAP kinase promotes cardiac hypertrophy via a putative paracrine interleukin-6 signaling mechanism. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 32. issue 9. 2019-03-21. PMID:29601781. |
isoproterenol infusion in control mice promoted overt cardiac hypertrophy and dysfunction (reduced ejection fraction, increased end systolic volume, increased cardiac weight index, increased cardiomyocyte area, increased fibrosis, and up-regulation of myocyte fetal genes and hypertrophy-associated micrornas). |
2019-03-21 |
2023-08-13 |
mouse |
| Chih-Chung Feng, Po-Hsiang Liao, Hsiang-I Tsai, Shiu-Min Cheng, Liang-Yo Yang, Vijaya PadmaViswanadha, Lung-Fa Pan, Ray-Jade Chen, Jeng-Fan Lo, Chih-Yang Huan. Tumorous imaginal disc 1 (TID1) inhibits isoproterenol-induced cardiac hypertrophy and apoptosis by regulating c-terminus of hsc70-interacting protein (CHIP) mediated degradation of Gαs. International journal of medical sciences. vol 15. issue 13. 2019-02-26. PMID:30443176. |
tid1 also plays a major role in preventing dcm; however, the role of tid1 in isoproterenol (iso)-induced cardiac apoptosis and hypertrophy remains unclear. |
2019-02-26 |
2023-08-13 |
human |
| Asmaa A Ahmed, Amany A E Ahmed, Engy M El Morsy, Shahira Nofa. Dimethyl fumarate interferes with MyD88-dependent toll-like receptor signalling pathway in isoproterenol-induced cardiac hypertrophy model. The Journal of pharmacy and pharmacology. vol 70. issue 11. 2019-01-18. PMID:30175489. |
to investigate the effect of dimethyl fumarate (dmf) on toll-like receptor (tlr) signalling pathway in isoproterenol (iso)-induced cardiac hypertrophy in rats. |
2019-01-18 |
2023-08-13 |
rat |
| S W Tobin, S Hashemi, K Dadson, S Turdi, K Ebrahimian, J Zhao, G Sweeney, J Grigull, J C McDermot. Heart Failure and MEF2 Transcriptome Dynamics in Response to β-Blockers. Scientific reports. vol 7. issue 1. 2019-01-10. PMID:28667250. |
rarres2 was identified as a novel mef2 target gene that is upregulated with tac in vivo and isoproterenol treatment in vitro which may have implications in cardiomyocyte apoptosis and hypertrophy. |
2019-01-10 |
2023-08-13 |
mouse |
| Subbiah Ramasamy, Ganesan Velmurugan, Balakrishnan Rekha, Sivakumar Anusha, K Shanmugha Rajan, Suresh Shanmugarajan, Tharmarajan Ramprasath, Pandi Gopal, Dhanendra Tomar, Karuppusamy V Karthik, Suresh Kumar Verma, Venkata Naga Srikanth Garikipati, Rajan Sudarsa. Egr-1 mediated cardiac miR-99 family expression diverges physiological hypertrophy from pathological hypertrophy. Experimental cell research. vol 365. issue 1. 2019-01-02. PMID:29481791. |
physiological and pathological cardiac hypertrophy was induced in h9c2 cardiomyoblast cell lines using α-2m and isoproterenol respectively. |
2019-01-02 |
2023-08-13 |
Not clear |
| Jing Gao, Yuhong Li, Tongmei Wang, Zhuo Shi, Yiqi Zhang, Shuang Liu, Pushuai Wen, Chunyan M. Analyzing gene expression profiles with preliminary validations in cardiac hypertrophy induced by pressure overload. Canadian journal of physiology and pharmacology. vol 96. issue 8. 2018-11-02. PMID:29510080. |
furthermore, the top degs were further validated using quantitative pcr in the hypertrophic heart tissue induced by isoprenaline. |
2018-11-02 |
2023-08-13 |
Not clear |
| Zhao Li, Yamin Liu, Xiaofan Guo, Guozhe Sun, Qun Ma, Ying Dai, Guangshuo Zhu, Yingxian Su. Long noncoding RNA myocardial infarction‑associated transcript is associated with the microRNA‑150‑5p/P300 pathway in cardiac hypertrophy. International journal of molecular medicine. vol 42. issue 3. 2018-10-26. PMID:29786749. |
neonatal rat ventricular myocytes (nrvms) were induced by isoproterenol (iso) to create a cell hypertrophy model, and mice were intraperitoneally injected with iso to establish an animal model. |
2018-10-26 |
2023-08-13 |
mouse |
| Jie-Kun Cheng, Xiao-Hui Sun, Li-Ping Gao, Le L. [Effects of fasudil on isoproterenol induced cardiac hypertrophy in rats]. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology. vol 32. issue 5. 2018-10-18. PMID:29931844. |
[effects of fasudil on isoproterenol induced cardiac hypertrophy in rats]. |
2018-10-18 |
2023-08-13 |
rat |
| Jie-Kun Cheng, Xiao-Hui Sun, Li-Ping Gao, Le L. [Effects of fasudil on isoproterenol induced cardiac hypertrophy in rats]. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology. vol 32. issue 5. 2018-10-18. PMID:29931844. |
to investigate the effects and mechanisms of fasudil (fas) on cardiac hypertrophy (ch) induced by isoprenaline(iso) in rats. |
2018-10-18 |
2023-08-13 |
rat |
| Nikhat Saleem, Anamika Prasad, Shyamal K Goswam. Apocynin prevents isoproterenol-induced cardiac hypertrophy in rat. Molecular and cellular biochemistry. vol 445. issue 1-2. 2018-09-17. PMID:29256115. |
as evident from the hw/bw ratio, hw/tl ratio, echocardiography, and histopathology, hypertrophic responses induced by isoproterenol (iso; 5 mg/kg body weight, subcutaneous) were blocked by apo (10 mg/kg body weight, intraperitoneal). |
2018-09-17 |
2023-08-13 |
rat |
| Hua-Li Chen, Yan Liu, Wei Jiang, Xiao-Xiao Wang, Guo-Lin Yuan, Yi-Lin Zhao, Chao Y. Secretoneurin suppresses cardiac hypertrophy through suppression of oxidant stress. European journal of pharmacology. vol 822. 2018-08-20. PMID:29337195. |
we observed that, in isoproterenol (iso) treatment induced cardiac or cardiomyocytes hypertrophy, a marked increase in the expression of endogenous sn in mouse plasma, myocardium and primary-cultured cardiomyocytes occurs. |
2018-08-20 |
2023-08-13 |
mouse |
| Mohammad Nazmul Alam, Md Murad Hossain, Md Mizanur Rahman, Nusrat Subhan, Md Abdullah Al Mamun, Anayt Ulla, Hasan Mahmud Reza, Md Ashraful Ala. Astaxanthin Prevented Oxidative Stress in Heart and Kidneys of Isoproterenol-Administered Aged Rats. Journal of dietary supplements. vol 15. issue 1. 2018-08-13. PMID:28489954. |
the objective of this study was to investigate the effect of astaxanthin on isoproterenol (iso)-induced myocardial infarction and cardiac hypertrophy in rats. |
2018-08-13 |
2023-08-13 |
rat |
| Yonggang Yuan, Wanzhong Peng, Yongxing Liu, Zesheng X. Palmatine attenuates isoproterenol-induced pathological hypertrophy via selectively inhibiting HDAC2 in rats. International journal of immunopathology and pharmacology. vol 30. issue 4. 2018-08-13. PMID:29164959. |
rat hypertrophy model was established by intraperitoneal isoproterenol (iso) injection. |
2018-08-13 |
2023-08-13 |
rat |
| Yuhee Ryu, Li Jin, Hae Jin Kee, Zhe Hao Piao, Jae Yeong Cho, Gwi Ran Kim, Sin Young Choi, Ming Quan Lin, Myung Ho Jeon. Gallic acid prevents isoproterenol-induced cardiac hypertrophy and fibrosis through regulation of JNK2 signaling and Smad3 binding activity. Scientific reports. vol 6. 2018-06-18. PMID:27703224. |
cardiac hypertrophy was induced by isoproterenol (isp) in mice and primary neonatal cardiomyocytes. |
2018-06-18 |
2023-08-13 |
mouse |
| Siyuan Wu, Lihui Lu, Mingyue Zhao, Wenchao Wu, Hua Fu, Xiajing Li. [Study on Potential Role of Calreticulin in Pressure Overload Induced Cardiac Hypertrophy]. Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi. vol 33. issue 3. 2018-05-24. PMID:29709152. |
this study aims to investigate the role of calreticulin in(crt)pressure overload induced cardiac hypertrophy.in our study,cardiac hypertrophy was induced by left ventricular pressure overload in male sd rats subjected to transverse aortic constriction(tac)operation.expression of gene and protein of calreticulin,markers of cardiac hypertrophy and endoplasmic reticulum stress(ers)were measured with real-time qpcr and western blot respectively.meanwhile,atorvastatin(a known ers inhibitor)and calreticulin-specific small interference ribonucleic acid(sirna)were used to inhibit the expression of ers and calreticulin respectively.the experimental data demonstrated that the gene and protein levels of calreticulin,hypertrophic and ers markers were increased significantly in the heart tissues of tac rat models after 4weeks.moreover,atorvastatin administration improved the cardiac function and reduced the expression of calreticulin and ers markers in tac rats.in addition,cultured primary neonatal rat cardiomyocytes(ncms)were treated with norepinephrine(ne),angiotensionⅡ(angⅡ)or isoprenaline(iso)to induce hypertrophic phenotype and ers.the expression of hypertrophic markers was reduced in ncms transfected with calreticulin-sirna.the results suggested that calreticulin might be a promising target for the treatment of cardiac hypertrophy. |
2018-05-24 |
2023-08-13 |
rat |