| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zhen-Guo Ma, Yu-Pei Yuan, Xin Zhang, Si-Chi Xu, Sha-Sha Wang, Qi-Zhu Tan. Piperine Attenuates Pathological Cardiac Fibrosis Via PPAR-γ/AKT Pathways. EBioMedicine. vol 18. 2018-01-17. PMID:28330809. |
here, we show that piperine-treated mice had similar hypertrophic responses as mice treated with vehicle but exhibited significantly attenuated cardiac fibrosis after pressure overload or isoprenaline (iso) injection. |
2018-01-17 |
2023-08-13 |
mouse |
| Chunmei Li, Dan Huang, Jing Tang, Mengqing Chen, Qun Lu, He Li, Mengzhen Zhang, Bin Xu, Jianwen Ma. ClC-3 chloride channel is involved in isoprenaline-induced cardiac hypertrophy. Gene. vol 642. 2017-12-26. PMID:29158167. |
isoprenaline, an activator of β-adrenergic receptor, has been found to induce cardiac hypertrophy in vivo and in vitro, but the exact mechanism is still unclear. |
2017-12-26 |
2023-08-13 |
mouse |
| Yuhua Fan, Li Liu, Kun Fang, Tao Huang, Lin Wan, Youbin Liu, Sen Zhang, Dongxia Yan, Guangnan Li, Yanhui Gao, Yanjie Lv, Yanjun Chen, Yingfeng T. Resveratrol Ameliorates Cardiac Hypertrophy by Down-regulation of miR-155 Through Activation of Breast Cancer Type 1 Susceptibility Protein. Journal of the American Heart Association. vol 5. issue 4. 2017-11-02. PMID:27107135. |
the polyphenol resveratrol (rev) has been reported to exhibit cardioprotective effects, such as inhibition of tac (transverse aortic constriction) or isoprenaline (iso)-induced hypertrophy. |
2017-11-02 |
2023-08-13 |
Not clear |
| Rongrong Sun, Baoling Zhu, Kai Xiong, Yan Sun, Dandan Shi, Li Chen, Youyi Zhang, Zijian Li, Lixiang Xu. Senescence as a novel mechanism involved in β-adrenergic receptor mediated cardiac hypertrophy. PloS one. vol 12. issue 8. 2017-10-06. PMID:28783759. |
to verify this hypothesis and examine whether cardiac senescence is a novel mechanism of hypertrophy induced by isoproterenol, 2-month-old male sprague dawley rats were subjected to isoproterenol infusion (0.25mg/kg/day) for 7 days by subcutaneous injection). |
2017-10-06 |
2023-08-13 |
rat |
| Rongrong Sun, Baoling Zhu, Kai Xiong, Yan Sun, Dandan Shi, Li Chen, Youyi Zhang, Zijian Li, Lixiang Xu. Senescence as a novel mechanism involved in β-adrenergic receptor mediated cardiac hypertrophy. PloS one. vol 12. issue 8. 2017-10-06. PMID:28783759. |
our results showed for the first time that cardiac senescence is involved in the process of pathological cardiac hypertrophy induced by isoproterenol. |
2017-10-06 |
2023-08-13 |
rat |
| Ying Feng, Jun Cheng, Baozhu Wei, Yanggan Wan. CaMKII inhibition reduces isoproterenol-induced ischemia and arrhythmias in hypertrophic mice. Oncotarget. vol 8. issue 11. 2017-09-20. PMID:28177919. |
here, we investigated the effect of camkii inhibition in isoproterenol (iso)-induced arrhythmias in hypertrophic mice. |
2017-09-20 |
2023-08-13 |
mouse |
| W Xu, Y Wang, J Zhou, X Zhu, S Zhang, W Yuan, X Liu, Y Shi, L Cao, Q Zeng, Z Jiang, X Ye, Y Wan, X Peng, Y Deng, F Chen, X Wang, G Dai, S Luo, X Fan, X Mo, X Wu, Y L. Cardiac Specific Overexpression of hHole Attenuates Isoproterenol-Induced Hypertrophic Remodeling through Inhibition of Extracellular Signal-Regulated Kinases (ERKs) Signalling. Current molecular medicine. vol 16. issue 5. 2017-09-15. PMID:27211802. |
in a cardiac specific transgenic mouse model, it was observed that overexpression of hhole specifically in heart attenuated cardiac hypertrophy and fibrosis induced by isoproterenol (iso), with blunted transcriptions of erk1/2, total erk1/2 proteins and phosphorylated erk1/2 (p-erk1/2) levels. |
2017-09-15 |
2023-08-13 |
mouse |
| Anne Järve, Silke Mühlstedt, Fatimunnisa Qadri, Bernadette Nickl, Herbert Schulz, Norbert Hübner, Cemil Özcelik, Michael Bade. Adverse left ventricular remodeling by glycoprotein nonmetastatic melanoma protein B in myocardial infarction. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 31. issue 2. 2017-09-01. PMID:28148779. |
moreover, gpnmb deficiency attenuated the dilated cardiomyopathy in muscle lim protein knockout mice but could not prevent cardiac hypertrophy induced by isoprenaline infusion. |
2017-09-01 |
2023-08-13 |
mouse |
| Jie Lou, Dan Zhao, Ling-Ling Zhang, Shu-Ying Song, Yan-Chao Li, Fei Sun, Xiao-Qing Ding, Chang-Jiang Yu, Yuan-Yuan Li, Mei-Tong Liu, Chang-Jiang Dong, Yong Ji, Hongliang Li, Wenfeng Chu, Zhi-Ren Zhan. Type III Transforming Growth Factor-β Receptor Drives Cardiac Hypertrophy Through β-Arrestin2-Dependent Activation of Calmodulin-Dependent Protein Kinase II. Hypertension (Dallas, Tex. : 1979). vol 68. issue 3. 2017-08-07. PMID:27432858. |
cardiac-specific transgenic expression of tβriii independently led to cardiac hypertrophy in mice, which was further aggravated by isoproterenol and tac treatment. |
2017-08-07 |
2023-08-13 |
mouse |
| Jamaira A Victorio, Stefano P Clerici, Roberto Palacios, María J Alonso, Dalton V Vassallo, Iris Z Jaffe, Luciana V Rossoni, Ana P Dave. Spironolactone Prevents Endothelial Nitric Oxide Synthase Uncoupling and Vascular Dysfunction Induced by β-Adrenergic Overstimulation: Role of Perivascular Adipose Tissue. Hypertension (Dallas, Tex. : 1979). vol 68. issue 3. 2017-08-07. PMID:27432866. |
β-ar overstimulation with associated cardiac hypertrophy and increased vasoconstrictor response to phenylephrine in aorta were modeled in rats by 7-day isoproterenol treatment. |
2017-08-07 |
2023-08-13 |
rat |
| Lung-Shuo Wang, Chun-Ting Lee, Wei-Lieh Su, Shih-Che Huang, Shu-Chi Wan. Delonix regia Leaf Extract (DRLE): A Potential Therapeutic Agent for Cardioprotection. PloS one. vol 11. issue 12. 2017-07-10. PMID:27936072. |
in this study, we found that the delonix regia leaf extract (drle) (400 mg/kg/d) can reduce the mortality rate in an isoproterenol (iso)-induced heart injury and hypertrophy mouse model. |
2017-07-10 |
2023-08-13 |
mouse |
| Jing Lu, Duanping Sun, Zhiping Liu, Min Li, Huiqi Hong, Cui Liu, Si Gao, Hong Li, Yi Cai, Shaorui Chen, Zhuoming Li, Jiantao Ye, Peiqing Li. SIRT6 suppresses isoproterenol-induced cardiac hypertrophy through activation of autophagy. Translational research : the journal of laboratory and clinical medicine. vol 172. 2017-06-26. PMID:27016702. |
primary neonatal rat cardiomyocytes (nrcms) or sprague-dawley (sd) rats were submitted to isoproterenol (iso) treatment, and then the hypertrophic responses and changes in autophagy activity were measured. |
2017-06-26 |
2023-08-13 |
rat |
| Quanlu Duan, Li Ni, Peihua Wang, Chen Chen, Lei Yang, Ben Ma, Wei Gong, Zhejun Cai, Ming-Hui Zou, Dao Wen Wan. Deregulation of XBP1 expression contributes to myocardial vascular endothelial growth factor-A expression and angiogenesis during cardiac hypertrophy in vivo. Aging cell. vol 15. issue 4. 2017-06-05. PMID:27133203. |
western blots showed that myocardial xbp1s protein was significantly increased in both isoproterenol (iso)-induced and pressure-overload-induced hypertrophic and failing heart compared to normal control. |
2017-06-05 |
2023-08-13 |
human |
| Zaid H Maayah, Hassan N Althurwi, Ahmed A El-Sherbeni, Ghada Abdelhamid, Arno G Siraki, Ayman O S El-Kad. The role of cytochrome P450 1B1 and its associated mid-chain hydroxyeicosatetraenoic acid metabolites in the development of cardiac hypertrophy induced by isoproterenol. Molecular and cellular biochemistry. vol 429. issue 1-2. 2017-05-12. PMID:28251434. |
the role of cytochrome p450 1b1 and its associated mid-chain hydroxyeicosatetraenoic acid metabolites in the development of cardiac hypertrophy induced by isoproterenol. |
2017-05-12 |
2023-08-13 |
human |
| Zaid H Maayah, Hassan N Althurwi, Ahmed A El-Sherbeni, Ghada Abdelhamid, Arno G Siraki, Ayman O S El-Kad. The role of cytochrome P450 1B1 and its associated mid-chain hydroxyeicosatetraenoic acid metabolites in the development of cardiac hypertrophy induced by isoproterenol. Molecular and cellular biochemistry. vol 429. issue 1-2. 2017-05-12. PMID:28251434. |
however, the ability of isoproterenol (iso) to induce cardiac hypertrophy through mid-chain hetes has not been investigated yet. |
2017-05-12 |
2023-08-13 |
human |
| Sophie Clouet, Larissa Di Pietrantonio, Evangelos-Panagiotis Daskalopoulos, Hrag Esfahani, Michael Horckmans, Marion Vanorlé, Anne Lemaire, Jean-Luc Balligand, Christophe Beauloye, Jean-Marie Boeynaems, Didier Commun. Loss of Mouse P2Y6 Nucleotide Receptor Is Associated with Physiological Macrocardia and Amplified Pathological Cardiac Hypertrophy. The Journal of biological chemistry. vol 291. issue 30. 2017-05-08. PMID:27231349. |
we then observed that loss of p2y6 receptor enhanced pathological cardiac hypertrophy induced after isoproterenol injection. |
2017-05-08 |
2023-08-13 |
mouse |
| Lei Liu, Chao Wang, Yan Lin, Yuhui Xi, Hong Li, Sa Shi, Hongzhu Li, Weihua Zhang, Yajun Zhao, Ye Tian, Changqing Xu, Lina Wan. Suppression of calcium‑sensing receptor ameliorates cardiac hypertrophy through inhibition of autophagy. Molecular medicine reports. vol 14. issue 1. 2017-04-06. PMID:27176663. |
isoproterenol (iso) was used to induce cardiac hypertrophy in wistar rats. |
2017-04-06 |
2023-08-13 |
rat |
| Ronghui Han, Futian Tang, Meili Lu, Chonghua Xu, Jin Hu, Meng Mei, Hongxin Wan. Protective effects of Astragalus polysaccharides against endothelial dysfunction in hypertrophic rats induced by isoproterenol. International immunopharmacology. vol 38. 2017-04-06. PMID:27344039. |
protective effects of astragalus polysaccharides against endothelial dysfunction in hypertrophic rats induced by isoproterenol. |
2017-04-06 |
2023-08-13 |
rat |
| Ronghui Han, Futian Tang, Meili Lu, Chonghua Xu, Jin Hu, Meng Mei, Hongxin Wan. Protective effects of Astragalus polysaccharides against endothelial dysfunction in hypertrophic rats induced by isoproterenol. International immunopharmacology. vol 38. 2017-04-06. PMID:27344039. |
the present study was designed to evaluate the protective effect of aps on vascular endothelia in cardiac hypertrophy rats induced by isoproterenol (iso). |
2017-04-06 |
2023-08-13 |
rat |
| Megha Prasad, Jeffrey B Geske, Paul Sorajja, Steve R Ommen, Hartzell V Schaff, Bernard J Gersh, Rick A Nishimur. Hemodynamic changes in systolic and diastolic function during isoproterenol challenge predicts symptomatic response to myectomy in hypertrophic cardiomyopathy with labile obstruction. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions. vol 88. issue 6. 2017-03-21. PMID:27062082. |
hemodynamic changes in systolic and diastolic function during isoproterenol challenge predicts symptomatic response to myectomy in hypertrophic cardiomyopathy with labile obstruction. |
2017-03-21 |
2023-08-13 |
Not clear |