Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Zaid H Maayah, Hassan N Althurwi, Ahmed A El-Sherbeni, Ghada Abdelhamid, Arno G Siraki, Ayman O S El-Kad. The role of cytochrome P450 1B1 and its associated mid-chain hydroxyeicosatetraenoic acid metabolites in the development of cardiac hypertrophy induced by isoproterenol. Molecular and cellular biochemistry. vol 429. issue 1-2. 2017-05-12. PMID:28251434. |
however, the ability of isoproterenol (iso) to induce cardiac hypertrophy through mid-chain hetes has not been investigated yet. |
2017-05-12 |
2023-08-13 |
human |
Sophie Clouet, Larissa Di Pietrantonio, Evangelos-Panagiotis Daskalopoulos, Hrag Esfahani, Michael Horckmans, Marion Vanorlé, Anne Lemaire, Jean-Luc Balligand, Christophe Beauloye, Jean-Marie Boeynaems, Didier Commun. Loss of Mouse P2Y6 Nucleotide Receptor Is Associated with Physiological Macrocardia and Amplified Pathological Cardiac Hypertrophy. The Journal of biological chemistry. vol 291. issue 30. 2017-05-08. PMID:27231349. |
we then observed that loss of p2y6 receptor enhanced pathological cardiac hypertrophy induced after isoproterenol injection. |
2017-05-08 |
2023-08-13 |
mouse |
Lei Liu, Chao Wang, Yan Lin, Yuhui Xi, Hong Li, Sa Shi, Hongzhu Li, Weihua Zhang, Yajun Zhao, Ye Tian, Changqing Xu, Lina Wan. Suppression of calcium‑sensing receptor ameliorates cardiac hypertrophy through inhibition of autophagy. Molecular medicine reports. vol 14. issue 1. 2017-04-06. PMID:27176663. |
isoproterenol (iso) was used to induce cardiac hypertrophy in wistar rats. |
2017-04-06 |
2023-08-13 |
rat |
Ronghui Han, Futian Tang, Meili Lu, Chonghua Xu, Jin Hu, Meng Mei, Hongxin Wan. Protective effects of Astragalus polysaccharides against endothelial dysfunction in hypertrophic rats induced by isoproterenol. International immunopharmacology. vol 38. 2017-04-06. PMID:27344039. |
protective effects of astragalus polysaccharides against endothelial dysfunction in hypertrophic rats induced by isoproterenol. |
2017-04-06 |
2023-08-13 |
rat |
Ronghui Han, Futian Tang, Meili Lu, Chonghua Xu, Jin Hu, Meng Mei, Hongxin Wan. Protective effects of Astragalus polysaccharides against endothelial dysfunction in hypertrophic rats induced by isoproterenol. International immunopharmacology. vol 38. 2017-04-06. PMID:27344039. |
the present study was designed to evaluate the protective effect of aps on vascular endothelia in cardiac hypertrophy rats induced by isoproterenol (iso). |
2017-04-06 |
2023-08-13 |
rat |
Megha Prasad, Jeffrey B Geske, Paul Sorajja, Steve R Ommen, Hartzell V Schaff, Bernard J Gersh, Rick A Nishimur. Hemodynamic changes in systolic and diastolic function during isoproterenol challenge predicts symptomatic response to myectomy in hypertrophic cardiomyopathy with labile obstruction. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions. vol 88. issue 6. 2017-03-21. PMID:27062082. |
hemodynamic changes in systolic and diastolic function during isoproterenol challenge predicts symptomatic response to myectomy in hypertrophic cardiomyopathy with labile obstruction. |
2017-03-21 |
2023-08-13 |
Not clear |
Megha Prasad, Jeffrey B Geske, Paul Sorajja, Steve R Ommen, Hartzell V Schaff, Bernard J Gersh, Rick A Nishimur. Hemodynamic changes in systolic and diastolic function during isoproterenol challenge predicts symptomatic response to myectomy in hypertrophic cardiomyopathy with labile obstruction. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions. vol 88. issue 6. 2017-03-21. PMID:27062082. |
we aimed to assess the utility of changes in systolic and diastolic function by isoproterenol challenge in predicting symptom resolution post-myectomy in selected patients with hypertrophic cardiomyopathy (hcm) and labile obstruction. |
2017-03-21 |
2023-08-13 |
Not clear |
Jing-Jing Liu, Cui-Mei Zhao, Zhi-Gang Li, Yu-Mei Wang, Wei Miao, Xiu-Juan Wu, Wen-Jing Wang, Chang Liu, Duo Wang, Kang Wang, Li Li, Lu-Ying Pen. miR-218 Involvement in Cardiomyocyte Hypertrophy Is Likely through Targeting REST. International journal of molecular sciences. vol 17. issue 6. 2017-03-17. PMID:27258257. |
overexpression of mir-218 is sufficient to reduce hypertrophy, whereas the suppression of mir-218 aggravates hypertrophy in primary cardiomyocytes induced by isoprenaline (iso). |
2017-03-17 |
2023-08-13 |
mouse |
Debabrata Chowdhury, Dinesh Kumar, Utpal Bhadra, Tangutur Anjana Devi, Manika Pal Bhadr. Prohibitin confers cytoprotection against ISO-induced hypertrophy in H9c2 cells via attenuation of oxidative stress and modulation of Akt/Gsk-3β signaling. Molecular and cellular biochemistry. vol 425. issue 1-2. 2017-02-17. PMID:27854077. |
numerous hypertrophic stimuli, including β-adrenergic agonists such as isoproterenol (iso), result in generation of reactive oxygen species (ros) and alteration in the mitochondrial membrane potential (Δψ) leading to oxidative stress. |
2017-02-17 |
2023-08-13 |
rat |
Yan Lin, Jingbin Zhu, Xiaojie Zhang, Jun Wang, Wei Xiao, Bo Li, Li Jin, Jie Lian, Li Zhou, Jicheng Li. Inhibition of Cardiomyocytes Hypertrophy by Resveratrol Is Associated with Amelioration of Endoplasmic Reticulum Stress. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. vol 39. issue 2. 2017-02-10. PMID:27467279. |
this study was undertaken to investigate whether res can protect the heart suffering from hypertrophy injuries induced by isoproterenol (iso), and whether the protective effect is mediated by endoplasmic reticulum (er) stress. |
2017-02-10 |
2023-08-13 |
Not clear |
Xilan Tang, Xiaohong Tracey Gan, Venkatesh Rajapurohitam, Cathy Xiaoling Huang, Jenny Xue, Edmund M K Lui, Morris Karmazy. North American ginseng (Panax quinquefolius) suppresses β-adrenergic-dependent signalling, hypertrophy, and cardiac dysfunction. Canadian journal of physiology and pharmacology. vol 94. issue 12. 2017-02-10. PMID:27797280. |
here, we determined whether north american ginseng can modulate the deleterious effects of the β-adrenoceptor agonist isoproterenol on cardiac hypertrophy and function using in vitro and in vivo approaches. |
2017-02-10 |
2023-08-13 |
rat |
Xilan Tang, Xiaohong Tracey Gan, Venkatesh Rajapurohitam, Cathy Xiaoling Huang, Jenny Xue, Edmund M K Lui, Morris Karmazy. North American ginseng (Panax quinquefolius) suppresses β-adrenergic-dependent signalling, hypertrophy, and cardiac dysfunction. Canadian journal of physiology and pharmacology. vol 94. issue 12. 2017-02-10. PMID:27797280. |
in in vitro studies, ginseng (10 μg/ml) completely suppressed the hypertrophic response to 1 μmol/l isoproterenol in terms of myocyte surface area, as well as reduction in the upregulation of fetal gene expression. |
2017-02-10 |
2023-08-13 |
rat |
Chonghua Xu, Futian Tang, Meili Lu, Jing Yang, Ronghui Han, Meng Mei, Jin Hu, Mingsheng Zhou, Hongxin Wan. Astragaloside IV improves the isoproterenol-induced vascular dysfunction via attenuating eNOS uncoupling-mediated oxidative stress and inhibiting ROS-NF-κB pathways. International immunopharmacology. vol 33. 2016-12-13. PMID:26903414. |
our previous studies demonstrated that astragaloside iv (asiv) could protect against cardiac hypertrophy in rats induced by isoproterenol (iso), but its effects on the aorta are not known. |
2016-12-13 |
2023-08-13 |
rat |
Govindan Sangaran Jagadeesh, M F Nagoor Meeran, Palanisamy Selvara. Protective Effects of 7-Hydroxycoumarin on Dyslipidemia and Cardiac Hypertrophy in Isoproterenol-Induced Myocardial Infarction in Rats. Journal of biochemical and molecular toxicology. vol 30. issue 3. 2016-11-14. PMID:26995004. |
this study evaluates the protective effects of 7-hydroxycoumarin (7-hc) on dyslipidemia and cardiac hypertrophy in isoproterenol (iso) induced myocardial infarction (mi) in rats. |
2016-11-14 |
2023-08-13 |
rat |
Meng Mei, Futian Tang, Meili Lu, Xin He, Hongxin Wang, Xuwei Hou, Jin Hu, Chonghua Xu, Ronghui Ha. Astragaloside IV attenuates apoptosis of hypertrophic cardiomyocyte through inhibiting oxidative stress and calpain-1 activation. Environmental toxicology and pharmacology. vol 40. issue 3. 2016-10-05. PMID:26433482. |
the present study was designed to investigate whether the inhibitory effect of asiv on isoproterenol (iso)-induced apoptosis of hypertrophic cardiomyocyte was associated with the anti-oxidation and calpain-1 inhibition. |
2016-10-05 |
2023-08-13 |
rat |
Lejla Medzikovic, Cees A Schumacher, Arie O Verkerk, Elza D van Deel, Rianne Wolswinkel, Ingeborg van der Made, Natascha Bleeker, Daniella Cakici, Maarten M G van den Hoogenhof, Farid Meggouh, Esther E Creemers, Carol Ann Remme, Antonius Baartscheer, Robbert J de Winter, Carlie J M de Vries, E Karin Arkenbout, Vivian de Waar. Orphan nuclear receptor Nur77 affects cardiomyocyte calcium homeostasis and adverse cardiac remodelling. Scientific reports. vol 5. 2016-09-14. PMID:26486271. |
in vivo, these differences resulted in larger cardiomyocytes, increased expression of hypertrophic genes, and more cardiac fibrosis in nur77-ko mice upon chronic isoproterenol stimulation. |
2016-09-14 |
2023-08-13 |
mouse |
Rukhsana Gul, Dae-Ryoung Park, Asif Iqbal Shawl, Soo-Yeul Im, Tae-Sik Nam, Sun-Hwa Lee, Jae-Ki Ko, Kyu Yoon Jang, Donghee Kim, Uh-Hyun Ki. Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) and Cyclic ADP-Ribose (cADPR) Mediate Ca2+ Signaling in Cardiac Hypertrophy Induced by β-Adrenergic Stimulation. PloS one. vol 11. issue 3. 2016-08-03. PMID:26959359. |
we investigated the role of ca2+-mobilizing second messengers, naadp and cadpr, in the cardiac hypertrophy induced by β-adrenergic stimulation by isoproterenol. |
2016-08-03 |
2023-08-13 |
mouse |
Rukhsana Gul, Dae-Ryoung Park, Asif Iqbal Shawl, Soo-Yeul Im, Tae-Sik Nam, Sun-Hwa Lee, Jae-Ki Ko, Kyu Yoon Jang, Donghee Kim, Uh-Hyun Ki. Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) and Cyclic ADP-Ribose (cADPR) Mediate Ca2+ Signaling in Cardiac Hypertrophy Induced by β-Adrenergic Stimulation. PloS one. vol 11. issue 3. 2016-08-03. PMID:26959359. |
cd38 knockout mice were rescued from chronic isoproterenol infusion-induced myocardial hypertrophy, interstitial fibrosis, and decrease in fractional shortening and ejection fraction. |
2016-08-03 |
2023-08-13 |
mouse |
Xinying Zhang, Tiemin Zhang, Jichao Wu, Xiangjing Yu, Dan Zheng, Fan Yang, Ting Li, Lina Wang, Yajun Zhao, Shiyun Dong, Xin Zhong, Songbin Fu, Chang-qing Xu, Fanghao Lu, Wei-hua Zhan. Calcium sensing receptor promotes cardiac fibroblast proliferation and extracellular matrix secretion. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. vol 33. issue 3. 2016-08-01. PMID:24603056. |
the present study investigated whether car played a role in cardiac fibroblast proliferation and extracellular matrix (ecm) secretion, both in cultured rat neonatal cardiac fibroblasts and in a model of cardiac hypertrophy induced by isoproterenol (iso). |
2016-08-01 |
2023-08-12 |
rat |
Xiangbo An, Jingjing Wang, Hao Li, Zhizhen Lu, Yan Bai, Han Xiao, Youyi Zhang, Yao Son. Speckle Tracking Based Strain Analysis Is Sensitive for Early Detection of Pathological Cardiac Hypertrophy. PloS one. vol 11. issue 2. 2016-07-21. PMID:26871457. |
here we report that speckle tracking-based strain analysis is more sensitive than conventional echocardiography for early detection of pathological cardiac hypertrophy in the isoproterenol (iso) mouse model. |
2016-07-21 |
2023-08-13 |
mouse |