| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ruotian Li, Guijun Yan, Qun Zhang, Yue Jiang, Haixiang Sun, Yali Hu, Jianxin Sun, Biao X. miR-145 inhibits isoproterenol-induced cardiomyocyte hypertrophy by targeting the expression and localization of GATA6. FEBS letters. vol 587. issue 12. 2013-08-14. PMID:23624080. |
here, we report mir-145 regulates both expression and localization of gata6, thereby protecting the heart against cardiomyocyte hypertrophy induced by isoproterenol (iso). |
2013-08-14 |
2023-08-12 |
mouse |
| Jing Lu, Zhou-Yan Bian, Ran Zhang, Yan Zhang, Chen Liu, Ling Yan, Shu-Min Zhang, Ding-Sheng Jiang, Xiang Wei, Xue Hai Zhu, Manyin Chen, Ai-Bing Wang, Yingjie Chen, Qinglin Yang, Peter P Liu, Hongliang L. Interferon regulatory factor 3 is a negative regulator of pathological cardiac hypertrophy. Basic research in cardiology. vol 108. issue 2. 2013-07-18. PMID:23307144. |
herein, we employed an irf3-deficient mouse model, cardiac-specific irf3-overexpression mouse model and isolated cardiomyocytes to investigate the role of irf3 in cardiac hypertrophy induced by aortic banding (ab) or isoproterenol (iso). |
2013-07-18 |
2023-08-12 |
mouse |
| Andrei Molojavyi, Antje Lindecke, Annika Raupach, Sarah Moellendorf, Karl K\\xc3\\xb6hrer, Axel G\\xc3\\xb6deck. Myoglobin-deficient mice activate a distinct cardiac gene expression program in response to isoproterenol-induced hypertrophy. Physiological genomics. vol 41. issue 2. 2013-07-15. PMID:20145201. |
to analyze to what extent myo-/- mice would tolerate cardiac stress we used the model of chronic isoproterenol application to induce cardiac hypertrophy in myo-/- mice and wild-type (wt) controls. |
2013-07-15 |
2023-08-12 |
mouse |
| Andrei Molojavyi, Antje Lindecke, Annika Raupach, Sarah Moellendorf, Karl K\\xc3\\xb6hrer, Axel G\\xc3\\xb6deck. Myoglobin-deficient mice activate a distinct cardiac gene expression program in response to isoproterenol-induced hypertrophy. Physiological genomics. vol 41. issue 2. 2013-07-15. PMID:20145201. |
after 14 days of isoproterenol infusion cardiac hypertrophy in wt and myo-/- mice reached a similar level. |
2013-07-15 |
2023-08-12 |
mouse |
| Ana Paula Nadu, Anderson J Ferreira, Timothy L Reudelhuber, Michael Bader, Robson A S Santo. Reduced isoproterenol-induced renin-angiotensin changes and extracellular matrix deposition in hearts of TGR(A1-7)3292 rats. Journal of the American Society of Hypertension : JASH. vol 2. issue 5. 2013-07-04. PMID:20409916. |
we investigated the expression of specific extracellular matrix (ecm) proteins in cardiac hypertrophy induced by isoproterenol in tgr(a1-7)3292 rats. |
2013-07-04 |
2023-08-12 |
rat |
| Rogerio Faustino Ribeiro, Felipe F Potratz, Brunella M M Pavan, Ludimila Forechi, Filipe Lugon Moulin Lima, Jonaina Fiorim, Aurelia Araujo Fernandes, Dalton Valentim Vassallo, Ivanita Stefano. Carvedilol prevents ovariectomy-induced myocardial contractile dysfunction in female rat. PloS one. vol 8. issue 1. 2013-07-01. PMID:23308166. |
carvedilol treatment in the ovx animals: prevented weight gain and slight hypertrophy, restored the reduced positive inotropic responses to ca(2+) and isoproterenol, prevented the reduction in serca2a expression, abolished the increase in superoxide anion production, normalized the increase in p22(phox) expression, and decreased serum angiotensin converting enzyme (ace) activity. |
2013-07-01 |
2023-08-12 |
rat |
| Isil Ozakca, Ebru Arioglu-Inan, Hrag Esfahani, V Melih Altan, Jean-Luc Balligand, Gizem Kayki-Mutlu, A Tanju Ozcelika. Nebivolol prevents desensitization of \\xce\\xb2-adrenoceptor signaling and induction of cardiac hypertrophy in response to isoprenaline beyond \\xce\\xb21-adrenoceptor blockage. American journal of physiology. Heart and circulatory physiology. vol 304. issue 9. 2013-06-28. PMID:23457011. |
nebivolol prevents desensitization of \xce\xb2-adrenoceptor signaling and induction of cardiac hypertrophy in response to isoprenaline beyond \xce\xb21-adrenoceptor blockage. |
2013-06-28 |
2023-08-12 |
rat |
| Vandana Sankar, Balasubramaniam Pangayarselvi, Ayyappan Prathapan, Kozhiparambil Gopalan Ragh. Desmodium gangeticum (Linn.) DC. exhibits antihypertrophic effect in isoproterenol-induced cardiomyoblasts via amelioration of oxidative stress and mitochondrial alterations. Journal of cardiovascular pharmacology. vol 61. issue 1. 2013-06-12. PMID:23052030. |
hypertrophy was induced by exposing h9c2 cell line to \xce\xb2-adrenergic receptor agonist, isoproterenol (iso), for 96 hours. |
2013-06-12 |
2023-08-12 |
Not clear |
| Qunhui Yang, Jiancheng Yang, Gaofeng Wu, Ying Feng, Qiufeng Lv, Shumei Lin, Jianmin H. Effects of taurine on myocardial cGMP/cAMP ratio, antioxidant ability, and ultrastructure in cardiac hypertrophy rats induced by isoproterenol. Advances in experimental medicine and biology. vol 776. 2013-06-12. PMID:23392885. |
effects of taurine on myocardial cgmp/camp ratio, antioxidant ability, and ultrastructure in cardiac hypertrophy rats induced by isoproterenol. |
2013-06-12 |
2023-08-12 |
human |
| Qunhui Yang, Jiancheng Yang, Gaofeng Wu, Ying Feng, Qiufeng Lv, Shumei Lin, Jianmin H. Effects of taurine on myocardial cGMP/cAMP ratio, antioxidant ability, and ultrastructure in cardiac hypertrophy rats induced by isoproterenol. Advances in experimental medicine and biology. vol 776. 2013-06-12. PMID:23392885. |
to investigate the preventive effects of taurine on cardiac hypertrophy in rats, myocardial injury was established by hypodermic injection of isoprenaline (iso) (10 mg/kg d) for 7 days. |
2013-06-12 |
2023-08-12 |
human |
| Qunhui Yang, Jiancheng Yang, Gaofeng Wu, Ying Feng, Qiufeng Lv, Shumei Lin, Jianmin H. Effects of taurine on myocardial cGMP/cAMP ratio, antioxidant ability, and ultrastructure in cardiac hypertrophy rats induced by isoproterenol. Advances in experimental medicine and biology. vol 776. 2013-06-12. PMID:23392885. |
in conclusion, the present study demonstrated that taurine could inhibit the injury induced by iso by increasing myocardial negative inotropic effect and antioxidant ability, decreasing the hypertrophic response to isoproterenol and protecting the integrity of -myocardial ultrastructure, decreasing myocardial leak of ck-mb. |
2013-06-12 |
2023-08-12 |
human |
| Ming-Zi Chen, Qing-Ting Bu, Shu-Chao Pang, Feng-Lan Li, Mei-Na Sun, Er-Fu Chu, Hui L. Tetrodotoxin attenuates isoproterenol-induced hypertrophy in H9c2 rat cardiac myocytes. Molecular and cellular biochemistry. vol 371. issue 1-2. 2013-05-17. PMID:22941212. |
the present study was carried out to determine whether the reversible sodium channel blocker tetrodotoxin (ttx) exerts a direct anti-hypertrophic effect on isoproterenol (iso)-induced cell hypertrophy and find the underlying mechanism that regulate [na(+)]( i ). |
2013-05-17 |
2023-08-12 |
rat |
| B M Patel, S S Agarwal, S V Bhadad. Perindopril protects against streptozotocin-induced hyperglycemic myocardial damage/alterations. Human & experimental toxicology. vol 31. issue 11. 2013-04-30. PMID:22653691. |
we studied the effect of perindopril (1 mg/kg/d orally [po]) on cardiovascular complications in neonatal model of rats, which was induced by administering stz (90 mg/kg, intraperitoneally [ip]), in 5-d-old wistar rats and cardiac hypertrophy induced by isoprenaline (iso; 5 mg/kg, ip) for 10 d. various biochemical, cardiac, and hemodynamic parameters were measured at the end of 8 weeks of treatment in diabetes model and 10 d in hypertrophy model. |
2013-04-30 |
2023-08-12 |
rat |
| Vinodkumar B Pillai, Nagalingam R Sundaresan, Gene Kim, Sadhana Samant, Liliana Moreno-Vinasco, Joe G N Garcia, Mahesh P Gupt. Nampt secreted from cardiomyocytes promotes development of cardiac hypertrophy and adverse ventricular remodeling. American journal of physiology. Heart and circulatory physiology. vol 304. issue 3. 2013-03-22. PMID:23203961. |
whereas nampt(+/-) mice were protected against agonist (isoproterenol and angiotensin ii)-induced hypertrophy, nampt transgenic mice spontaneously developed cardiac hypertrophy at 6 mo of age. |
2013-03-22 |
2023-08-12 |
mouse |
| Monica Flores-Mu\\xc3\\xb1oz, Bruno M D C Godinho, Abdulaziz Almalik, Stuart A Nickli. Adenoviral delivery of angiotensin-(1-7) or angiotensin-(1-9) inhibits cardiomyocyte hypertrophy via the mas or angiotensin type 2 receptor. PloS one. vol 7. issue 9. 2013-03-06. PMID:23029101. |
here, we have engineered adenoviral vectors expressing fusion proteins which release ang-(1-7) [radang-(1-7)] or ang-(1-9) [radang-(1-9)] and compared their effects on cardiomyocyte hypertrophy in rat h9c2 cardiomyocytes or primary adult rabbit cardiomyocytes, stimulated with angiotensin ii, isoproterenol or arg-vasopressin. |
2013-03-06 |
2023-08-12 |
rat |
| Beatriz Mart\\xc3\\xadn-Fern\\xc3\\xa1ndez, Natalia de las Heras, Mar\\xc3\\xada Miana, Sandra Ballesteros, Mar\\xc3\\xada Valero-Mu\\xc3\\xb1oz, Dalton Vassallo, Ana Paula Davel, Luciana Venturini Rossoni, Victoria Cachofeiro, Vicente Laher. Spironolactone prevents alterations associated with cardiac hypertrophy produced by isoproterenol in rats: involvement of serum- and glucocorticoid-regulated kinase type 1. Experimental physiology. vol 97. issue 6. 2013-01-18. PMID:22327331. |
spironolactone prevents alterations associated with cardiac hypertrophy produced by isoproterenol in rats: involvement of serum- and glucocorticoid-regulated kinase type 1. |
2013-01-18 |
2023-08-12 |
rat |
| Beatriz Mart\\xc3\\xadn-Fern\\xc3\\xa1ndez, Natalia de las Heras, Mar\\xc3\\xada Miana, Sandra Ballesteros, Mar\\xc3\\xada Valero-Mu\\xc3\\xb1oz, Dalton Vassallo, Ana Paula Davel, Luciana Venturini Rossoni, Victoria Cachofeiro, Vicente Laher. Spironolactone prevents alterations associated with cardiac hypertrophy produced by isoproterenol in rats: involvement of serum- and glucocorticoid-regulated kinase type 1. Experimental physiology. vol 97. issue 6. 2013-01-18. PMID:22327331. |
persistent \xce\xb2-adrenergic receptor stimulation with isoproterenol is associated with cardiac hypertrophy as well as cardiac synthesis of angiotensin ii. |
2013-01-18 |
2023-08-12 |
rat |
| Beatriz Mart\\xc3\\xadn-Fern\\xc3\\xa1ndez, Natalia de las Heras, Mar\\xc3\\xada Miana, Sandra Ballesteros, Mar\\xc3\\xada Valero-Mu\\xc3\\xb1oz, Dalton Vassallo, Ana Paula Davel, Luciana Venturini Rossoni, Victoria Cachofeiro, Vicente Laher. Spironolactone prevents alterations associated with cardiac hypertrophy produced by isoproterenol in rats: involvement of serum- and glucocorticoid-regulated kinase type 1. Experimental physiology. vol 97. issue 6. 2013-01-18. PMID:22327331. |
isoproterenol treatment induced cardiac hypertrophy and increased collagen content, both of which were normalized by spironolactone treatment. |
2013-01-18 |
2023-08-12 |
rat |
| Beatriz Mart\\xc3\\xadn-Fern\\xc3\\xa1ndez, Natalia de las Heras, Mar\\xc3\\xada Miana, Sandra Ballesteros, Mar\\xc3\\xada Valero-Mu\\xc3\\xb1oz, Dalton Vassallo, Ana Paula Davel, Luciana Venturini Rossoni, Victoria Cachofeiro, Vicente Laher. Spironolactone prevents alterations associated with cardiac hypertrophy produced by isoproterenol in rats: involvement of serum- and glucocorticoid-regulated kinase type 1. Experimental physiology. vol 97. issue 6. 2013-01-18. PMID:22327331. |
the observed reduction of the principal mediator of aldosterone cellular actions, sgk-1, by spironolactone in hearts from isoproterenol-treated rats suggests a role of mineralocorticoids in the cardiac hypertrophy, fibrosis, inflammation, oxidation and diastolic dysfunction induced by isoproterenol treatment in rats. |
2013-01-18 |
2023-08-12 |
rat |
| Subir Kumar Maulik, Pankaj Prabhakar, Amit Kumar Dinda, Sandeep Set. Genistein prevents isoproterenol-induced cardiac hypertrophy in rats. Canadian journal of physiology and pharmacology. vol 90. issue 8. 2013-01-11. PMID:22808991. |
isoproterenol (5 mg\xc2\xb7(kg body weight)(-1)) was injected subcutaneously once daily for 14 days to induced cardiac hypertrophy. |
2013-01-11 |
2023-08-12 |
rat |