| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yanfei Li, Linlin Ma, Sijie Gu, Jiewen Tian, Yilin Cao, Zi Jin, Jingyi Chen, Bingbing Gu, Jiayin Tu, Zhixiao Wang, Xinming Li, Zhongping Ning, Yueling Ji. UBE3A alleviates isoproterenol-induced cardiac hypertrophy through the inhibition of the TLR4/MMP-9 signaling pathway. Acta biochimica et biophysica Sinica. vol 52. issue 1. 2020-02-26. PMID:31681945. |
moreover, ube3a knockdown by sirnas accelerated cardiac hypertrophy, suggesting that increased ube3a expression induced by isoproterenol might be a protective response and ube3a might be a protective factor against cardiac hypertrophy. |
2020-02-26 |
2023-08-13 |
Not clear |
| Harry H Matundan, Jon Sin, Magali Noval Rivas, Michael C Fishbein, Thomas J Lehman, Shuang Chen, Roberta A Gottlieb, Timothy R Crother, Masanori Abe, Moshe Ardit. Myocardial fibrosis after adrenergic stimulation as a long-term sequela in a mouse model of Kawasaki disease vasculitis. JCI insight. vol 4. issue 3. 2020-02-25. PMID:30728329. |
we found that adrenergic stimulation with isoproterenol following lcwe-induced kd vasculitis in mice was associated with increased risk of cardiac hypertrophy and myocardial fibrosis, diminished ejection fraction, and increased serum levels of brain natriuretic peptide. |
2020-02-25 |
2023-08-13 |
mouse |
| Ying-Xu Wu, Jie-Kun Cheng, Le Li, Hou-Quan Ta. [Effects of chrysanthemum flower extract on cardiac hypertrophy induced by isoprenaline in mice]. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology. vol 35. issue 5. 2020-02-24. PMID:31894685. |
[effects of chrysanthemum flower extract on cardiac hypertrophy induced by isoprenaline in mice]. |
2020-02-24 |
2023-08-13 |
mouse |
| Jing-Xia Du, Jian-Zhao Wu, Zhi Li, Cai Zhang, Meng-Ting Shi, Jia Zhao, Man-Wen Jin, Hui Li. Pentamethylquercetin protects against cardiac remodeling via activation of Sestrin2. Biochemical and biophysical research communications. vol 512. issue 2. 2020-02-18. PMID:30898320. |
we generated a transverse aorta constriction (tac)-induced pressure-overload cardiac-remodeling model in mice, and also established an isoproterenol (iso)-induced neonatal rat cardiomyocyte (nrcm) hypertrophy model. |
2020-02-18 |
2023-08-13 |
mouse |
| Isadora Prado Cano, Thiago José Dionisio, Tânia Mary Cestari, Adriana Maria Calvo, Bella Luna Colombini-Ishikiriama, Flávio Augusto Cardoso Faria, Walter Luiz Siqueira, Carlos Ferreira Santo. Losartan and isoproterenol promote alterations in the local renin-angiotensin system of rat salivary glands. PloS one. vol 14. issue 5. 2020-02-03. PMID:31116771. |
isoproterenol treatment affected gene expression profiles in parotid (ace, ace-2, at1-a, mas, agt), and submandibular (ace, at2, agt) glands, thus promoting acinar hypertrophy in serous acini, without significant changes in salivary flow or total protein content. |
2020-02-03 |
2023-08-13 |
rat |
| Xue-Cui Wu, Yun Zhao, Cong Li, Hai-Rong Xiong, Zhi-Wei Zheng, Jun Zhou, Rong Liu, Wei Gong, Chao-Qi Li. [Expression and bioinformatics analysis of miRNA in ISO-induced rat cardiac hypertrophy]. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology. vol 35. issue 5. 2020-01-16. PMID:31894683. |
to investigate the expression changes of mirnas (mir199a-5p, mir206, mir133a-3p, mir499-5p) in rat model of cardiac hypertrophy induced by isoproterenol (iso), and to explore the main signal pathways and molecular mechanisms which related to that with the way of bioinformatics. |
2020-01-16 |
2023-08-13 |
rat |
| Miao Zhang, Qigen Du, Fubiao Yang, Ying Guo, Yunlong Hou, Pengyu Zh. Acupuncture at PC6 prevents cardiac hypertrophy in isoproterenol-treated mice. Acupuncture in medicine : journal of the British Medical Acupuncture Society. vol 37. issue 1. 2019-12-03. PMID:30843422. |
to investigate the effect of acupuncture at pc6 on cardiac hypertrophy in isoproterenol (iso)-treated mice. |
2019-12-03 |
2023-08-13 |
mouse |
| Jia Meng, Baoxue Yan. Protective Effect of Ganoderma (Lingzhi) on Cardiovascular System. Advances in experimental medicine and biology. vol 1182. 2019-12-02. PMID:31777019. |
some studies found that g. lucidum prevented from heart damage in a variety of disease models, such as streptozotocin (stz)-induced diabetic, high-fat-diet-induced diabetic, isoprenaline (iso)-induced myocardial hypertrophy, acute ethanol-induced heart toxicity, and transverse aortic constriction (tac) models. |
2019-12-02 |
2023-08-13 |
Not clear |
| Atsuki Imaeda, Shota Tanaka, Kota Tonegawa, Shota Fuchigami, Masanori Obana, Makiko Maeda, Miho Kihara, Hiroshi Kiyonari, Simon J Conway, Yasushi Fujio, Hiroyuki Nakayam. Myofibroblast β2 adrenergic signaling amplifies cardiac hypertrophy in mice. Biochemical and biophysical research communications. vol 510. issue 1. 2019-11-29. PMID:30683314. |
β2ar null mice exhibited attenuated hypertrophic responses to chronic βar stimulation upon continuous infusion of an agonist, isoprenaline (iso), compared to those in wildtype controls, suggesting that β2ar activation in the heart induces pro-hypertrophic effects in mice. |
2019-11-29 |
2023-08-13 |
mouse |
| X Fan, L Liu, Z Li, X Peng, Z Jiang, Y Guan, X Wu, X Yang, J Wan. Cardiomyocyte-specific TβR2 knockout mice are more susceptible to cardiac hypertrophy induced by adrenergic agonist stimulation. Current molecular medicine. 2019-11-20. PMID:26349497. |
although the mutant mice displayed no obvious physiological abnormality, they developed severer cardiac hypertrophy in response to isoproterenol (iso) stimulation than control mice did. |
2019-11-20 |
2023-08-13 |
mouse |
| Erratum for "Utility of Isoproterenol to Provoke Outflow Tract Gradients in Patients with Hypertrophic Cardiomyopathy" Am J Cardiol 2008;101:516-520. The American journal of cardiology. vol 120. issue 2. 2019-11-20. PMID:27887686. |
erratum for "utility of isoproterenol to provoke outflow tract gradients in patients with hypertrophic cardiomyopathy" am j cardiol 2008;101:516-520. |
2019-11-20 |
2023-08-13 |
Not clear |
| Xiuli Fang, Yajun Liu, Jing Lu, Huiqi Hong, Jing Yuan, Yuhong Zhang, Panxia Wang, Peiqing Liu, Jiantao Y. Protocatechuic aldehyde protects against isoproterenol-induced cardiac hypertrophy via inhibition of the JAK2/STAT3 signaling pathway. Naunyn-Schmiedeberg's archives of pharmacology. vol 391. issue 12. 2019-10-31. PMID:30132020. |
in this study, we showed that isoproterenol treatment (iso, 10 μm for 24 h) induced significant hypertrophy in cultured neonatal rat cardiomyocytes, as manifested by enlargement of cell surface area (1.74-fold greater than that of the control, p < 0.05) and upregulation of hypertrophic gene markers (2.44- to 2.75-fold increase in anf and β-mhc protein expression, p < 0.05). |
2019-10-31 |
2023-08-13 |
rat |
| Tahir Ali, Iram Mushtaq, Sonia Maryam, Anam Farhan, Kiran Saba, Muhammad Ishtiaq Jan, Aneesa Sultan, Mariam Anees, Burcu Duygu, Sadia Hamera, Sobia Tabassum, Qamar Javed, Paula A da Costa Martins, Iram Murtaz. Interplay of N acetyl cysteine and melatonin in regulating oxidative stress-induced cardiac hypertrophic factors and microRNAs. Archives of biochemistry and biophysics. vol 661. 2019-10-23. PMID:30439361. |
we aimed to measure the micrornas expressions in oxidative stress linked cardiac hypertrophic condition induced through stimulants as endothelin and isoproterenol. |
2019-10-23 |
2023-08-13 |
Not clear |
| Linyuan Shen, Mailin Gan, Zhengdong Tan, Dongmei Jiang, Yanzhi Jiang, Mingzhou Li, Jinyong Wang, Xuewei Li, Shunhua Zhang, Li Zh. A Novel Class of tRNA-Derived Small Non-Coding RNAs Respond to Myocardial Hypertrophy and Contribute to Intergenerational Inheritance. Biomolecules. vol 8. issue 3. 2019-09-18. PMID:30012983. |
in this study, we used an isoproterenol (iso)-induced myocardial hypertrophy rat model. |
2019-09-18 |
2023-08-13 |
rat |
| Linyuan Shen, Mailin Gan, Zhengdong Tan, Dongmei Jiang, Yanzhi Jiang, Mingzhou Li, Jinyong Wang, Xuewei Li, Shunhua Zhang, Li Zh. A Novel Class of tRNA-Derived Small Non-Coding RNAs Respond to Myocardial Hypertrophy and Contribute to Intergenerational Inheritance. Biomolecules. vol 8. issue 3. 2019-09-18. PMID:30012983. |
isoproterenol successfully induced a typical cardiac hypertrophy model in our study. |
2019-09-18 |
2023-08-13 |
rat |
| Yapeng Li, Dianhong Zhang, Lingyao Kong, Huiting Shi, Xinyu Tian, Lu Gao, Yuzhou Liu, Leiming Wu, Binbin Du, Zhen Huang, Cui Liang, Zheng Wang, Rui Yao, Yanzhou Zhan. Aldolase promotes the development of cardiac hypertrophy by targeting AMPK signaling. Experimental cell research. vol 370. issue 1. 2019-09-16. PMID:29902536. |
the mrna and protein levels of aldoa were significantly up-regulated in transverse aortic constriction (tac)- and isoproterenol (iso)-induced hypertrophic mouse hearts. |
2019-09-16 |
2023-08-13 |
mouse |
| Jing Yuan, Huiqi Hong, Yuhong Zhang, Jing Lu, Youhui Yu, Xueying Bi, Junjian Wang, Jiantao Y. Chrysophanol attenuated isoproterenol-induced cardiac hypertrophy by inhibiting Janus kinase 2/signal transducer and activator of transcription 3 signaling pathway. Cell biology international. vol 43. issue 6. 2019-09-09. PMID:30977566. |
in the current study, we found that chrysophanol could protect against isoproterenol (iso)-induced cardiac hypertrophy both in vitro and in vivo. |
2019-09-09 |
2023-08-13 |
rat |
| Qian Li, Zhuo-Ming Li, Shu-Ya Sun, Lu-Ping Wang, Pan-Xia Wang, Zhen Guo, Han-Wei Yang, Jian-Tao Ye, Jing Lu, Pei-Qing Li. PARP1 interacts with HMGB1 and promotes its nuclear export in pathological myocardial hypertrophy. Acta pharmacologica Sinica. vol 40. issue 5. 2019-07-29. PMID:30030529. |
primary-cultured neonatal rat cardiomyocytes (nrcms) were respectively incubated with three cardiac hypertrophic stimulants, including angiotensin ii (ang ii), phenylephrine (pe), and isoproterenol (iso), and cell surface area and the mrna expression of hypertrophic biomarkers were measured. |
2019-07-29 |
2023-08-13 |
rat |
| Mailin Gan, Ting Zheng, Linyuan Shen, Ya Tan, Yuan Fan, Surong Shuai, Lin Bai, Xuewei Li, Jinyong Wang, Shunhua Zhang, Li Zh. Genistein reverses isoproterenol-induced cardiac hypertrophy by regulating miR-451/TIMP2. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 112. 2019-07-22. PMID:30798118. |
in this study, h9c2 cells were treated with genistein, mir-451 mimic, mir-451 inhibitor and isoproterenol for 24 h, to study the effect of genistein on isoproterenol-induced myocardial hypertrophy in vitro. |
2019-07-22 |
2023-08-13 |
mouse |
| Mailin Gan, Ting Zheng, Linyuan Shen, Ya Tan, Yuan Fan, Surong Shuai, Lin Bai, Xuewei Li, Jinyong Wang, Shunhua Zhang, Li Zh. Genistein reverses isoproterenol-induced cardiac hypertrophy by regulating miR-451/TIMP2. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 112. 2019-07-22. PMID:30798118. |
results showed that isoproterenol induced cardiac hypertrophy and down-regulated the expression of mir-451 and up-regulated mir-451's target gene timp2. |
2019-07-22 |
2023-08-13 |
mouse |