| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Miao Zhang, Qigen Du, Fubiao Yang, Ying Guo, Yunlong Hou, Pengyu Zh. Acupuncture at PC6 prevents cardiac hypertrophy in isoproterenol-treated mice. Acupuncture in medicine : journal of the British Medical Acupuncture Society. vol 37. issue 1. 2019-12-03. PMID:30843422. |
to investigate the effect of acupuncture at pc6 on cardiac hypertrophy in isoproterenol (iso)-treated mice. |
2019-12-03 |
2023-08-13 |
mouse |
| Jia Meng, Baoxue Yan. Protective Effect of Ganoderma (Lingzhi) on Cardiovascular System. Advances in experimental medicine and biology. vol 1182. 2019-12-02. PMID:31777019. |
some studies found that g. lucidum prevented from heart damage in a variety of disease models, such as streptozotocin (stz)-induced diabetic, high-fat-diet-induced diabetic, isoprenaline (iso)-induced myocardial hypertrophy, acute ethanol-induced heart toxicity, and transverse aortic constriction (tac) models. |
2019-12-02 |
2023-08-13 |
Not clear |
| Atsuki Imaeda, Shota Tanaka, Kota Tonegawa, Shota Fuchigami, Masanori Obana, Makiko Maeda, Miho Kihara, Hiroshi Kiyonari, Simon J Conway, Yasushi Fujio, Hiroyuki Nakayam. Myofibroblast β2 adrenergic signaling amplifies cardiac hypertrophy in mice. Biochemical and biophysical research communications. vol 510. issue 1. 2019-11-29. PMID:30683314. |
β2ar null mice exhibited attenuated hypertrophic responses to chronic βar stimulation upon continuous infusion of an agonist, isoprenaline (iso), compared to those in wildtype controls, suggesting that β2ar activation in the heart induces pro-hypertrophic effects in mice. |
2019-11-29 |
2023-08-13 |
mouse |
| X Fan, L Liu, Z Li, X Peng, Z Jiang, Y Guan, X Wu, X Yang, J Wan. Cardiomyocyte-specific TβR2 knockout mice are more susceptible to cardiac hypertrophy induced by adrenergic agonist stimulation. Current molecular medicine. 2019-11-20. PMID:26349497. |
although the mutant mice displayed no obvious physiological abnormality, they developed severer cardiac hypertrophy in response to isoproterenol (iso) stimulation than control mice did. |
2019-11-20 |
2023-08-13 |
mouse |
| Erratum for "Utility of Isoproterenol to Provoke Outflow Tract Gradients in Patients with Hypertrophic Cardiomyopathy" Am J Cardiol 2008;101:516-520. The American journal of cardiology. vol 120. issue 2. 2019-11-20. PMID:27887686. |
erratum for "utility of isoproterenol to provoke outflow tract gradients in patients with hypertrophic cardiomyopathy" am j cardiol 2008;101:516-520. |
2019-11-20 |
2023-08-13 |
Not clear |
| Xiuli Fang, Yajun Liu, Jing Lu, Huiqi Hong, Jing Yuan, Yuhong Zhang, Panxia Wang, Peiqing Liu, Jiantao Y. Protocatechuic aldehyde protects against isoproterenol-induced cardiac hypertrophy via inhibition of the JAK2/STAT3 signaling pathway. Naunyn-Schmiedeberg's archives of pharmacology. vol 391. issue 12. 2019-10-31. PMID:30132020. |
in this study, we showed that isoproterenol treatment (iso, 10 μm for 24 h) induced significant hypertrophy in cultured neonatal rat cardiomyocytes, as manifested by enlargement of cell surface area (1.74-fold greater than that of the control, p < 0.05) and upregulation of hypertrophic gene markers (2.44- to 2.75-fold increase in anf and β-mhc protein expression, p < 0.05). |
2019-10-31 |
2023-08-13 |
rat |
| Tahir Ali, Iram Mushtaq, Sonia Maryam, Anam Farhan, Kiran Saba, Muhammad Ishtiaq Jan, Aneesa Sultan, Mariam Anees, Burcu Duygu, Sadia Hamera, Sobia Tabassum, Qamar Javed, Paula A da Costa Martins, Iram Murtaz. Interplay of N acetyl cysteine and melatonin in regulating oxidative stress-induced cardiac hypertrophic factors and microRNAs. Archives of biochemistry and biophysics. vol 661. 2019-10-23. PMID:30439361. |
we aimed to measure the micrornas expressions in oxidative stress linked cardiac hypertrophic condition induced through stimulants as endothelin and isoproterenol. |
2019-10-23 |
2023-08-13 |
Not clear |
| Linyuan Shen, Mailin Gan, Zhengdong Tan, Dongmei Jiang, Yanzhi Jiang, Mingzhou Li, Jinyong Wang, Xuewei Li, Shunhua Zhang, Li Zh. A Novel Class of tRNA-Derived Small Non-Coding RNAs Respond to Myocardial Hypertrophy and Contribute to Intergenerational Inheritance. Biomolecules. vol 8. issue 3. 2019-09-18. PMID:30012983. |
in this study, we used an isoproterenol (iso)-induced myocardial hypertrophy rat model. |
2019-09-18 |
2023-08-13 |
rat |
| Linyuan Shen, Mailin Gan, Zhengdong Tan, Dongmei Jiang, Yanzhi Jiang, Mingzhou Li, Jinyong Wang, Xuewei Li, Shunhua Zhang, Li Zh. A Novel Class of tRNA-Derived Small Non-Coding RNAs Respond to Myocardial Hypertrophy and Contribute to Intergenerational Inheritance. Biomolecules. vol 8. issue 3. 2019-09-18. PMID:30012983. |
isoproterenol successfully induced a typical cardiac hypertrophy model in our study. |
2019-09-18 |
2023-08-13 |
rat |
| Yapeng Li, Dianhong Zhang, Lingyao Kong, Huiting Shi, Xinyu Tian, Lu Gao, Yuzhou Liu, Leiming Wu, Binbin Du, Zhen Huang, Cui Liang, Zheng Wang, Rui Yao, Yanzhou Zhan. Aldolase promotes the development of cardiac hypertrophy by targeting AMPK signaling. Experimental cell research. vol 370. issue 1. 2019-09-16. PMID:29902536. |
the mrna and protein levels of aldoa were significantly up-regulated in transverse aortic constriction (tac)- and isoproterenol (iso)-induced hypertrophic mouse hearts. |
2019-09-16 |
2023-08-13 |
mouse |
| Jing Yuan, Huiqi Hong, Yuhong Zhang, Jing Lu, Youhui Yu, Xueying Bi, Junjian Wang, Jiantao Y. Chrysophanol attenuated isoproterenol-induced cardiac hypertrophy by inhibiting Janus kinase 2/signal transducer and activator of transcription 3 signaling pathway. Cell biology international. vol 43. issue 6. 2019-09-09. PMID:30977566. |
in the current study, we found that chrysophanol could protect against isoproterenol (iso)-induced cardiac hypertrophy both in vitro and in vivo. |
2019-09-09 |
2023-08-13 |
rat |
| Qian Li, Zhuo-Ming Li, Shu-Ya Sun, Lu-Ping Wang, Pan-Xia Wang, Zhen Guo, Han-Wei Yang, Jian-Tao Ye, Jing Lu, Pei-Qing Li. PARP1 interacts with HMGB1 and promotes its nuclear export in pathological myocardial hypertrophy. Acta pharmacologica Sinica. vol 40. issue 5. 2019-07-29. PMID:30030529. |
primary-cultured neonatal rat cardiomyocytes (nrcms) were respectively incubated with three cardiac hypertrophic stimulants, including angiotensin ii (ang ii), phenylephrine (pe), and isoproterenol (iso), and cell surface area and the mrna expression of hypertrophic biomarkers were measured. |
2019-07-29 |
2023-08-13 |
rat |
| Mailin Gan, Ting Zheng, Linyuan Shen, Ya Tan, Yuan Fan, Surong Shuai, Lin Bai, Xuewei Li, Jinyong Wang, Shunhua Zhang, Li Zh. Genistein reverses isoproterenol-induced cardiac hypertrophy by regulating miR-451/TIMP2. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 112. 2019-07-22. PMID:30798118. |
in this study, h9c2 cells were treated with genistein, mir-451 mimic, mir-451 inhibitor and isoproterenol for 24 h, to study the effect of genistein on isoproterenol-induced myocardial hypertrophy in vitro. |
2019-07-22 |
2023-08-13 |
mouse |
| Mailin Gan, Ting Zheng, Linyuan Shen, Ya Tan, Yuan Fan, Surong Shuai, Lin Bai, Xuewei Li, Jinyong Wang, Shunhua Zhang, Li Zh. Genistein reverses isoproterenol-induced cardiac hypertrophy by regulating miR-451/TIMP2. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 112. 2019-07-22. PMID:30798118. |
results showed that isoproterenol induced cardiac hypertrophy and down-regulated the expression of mir-451 and up-regulated mir-451's target gene timp2. |
2019-07-22 |
2023-08-13 |
mouse |
| Xiao-Chun Xiao, Wei-Hong Chen, Yuan-Yuan Cao, Yong-Jun Lou, Yuan Liu, Jin Wang, Xu-Feng Zhai, Nian-Sheng Li, Ying L. [Protective effect of Dendrobium candidum on isoproterenol induced cardiac hypertrophy in rats]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 43. issue 4. 2019-07-11. PMID:29600658. |
[protective effect of dendrobium candidum on isoproterenol induced cardiac hypertrophy in rats]. |
2019-07-11 |
2023-08-13 |
rat |
| Christoph D Rau, Milagros C Romay, Mary Tuteryan, Jessica J-C Wang, Marc Santolini, Shuxun Ren, Alain Karma, James N Weiss, Yibin Wang, Aldons J Lusi. Systems Genetics Approach Identifies Gene Pathways and Adamts2 as Drivers of Isoproterenol-Induced Cardiac Hypertrophy and Cardiomyopathy in Mice. Cell systems. vol 4. issue 1. 2019-07-01. PMID:27866946. |
we previously reported a genetic analysis of heart failure traits in a population of inbred mouse strains treated with isoproterenol to mimic catecholamine-driven cardiac hypertrophy. |
2019-07-01 |
2023-08-13 |
mouse |
| Linlin Shang, Lv Pin, Shanshan Zhu, Xiaohang Zhong, Yubiao Zhang, Mao Shun, Yunen Liu, Mingxiao Ho. Plantamajoside attenuates isoproterenol-induced cardiac hypertrophy associated with the HDAC2 and AKT/ GSK-3β signaling pathway. Chemico-biological interactions. vol 307. 2019-06-26. PMID:31009642. |
here, we investigated the effects and mechanism of pms on isoproterenol (iso)-induced cardiac hypertrophy. |
2019-06-26 |
2023-08-13 |
Not clear |
| Xinlei Hu, Qiong Ou-Yang, Lanlan Wang, Tingting Li, Xiaoxue Xie, Jun Li. AdipoRon prevents l-thyroxine or isoproterenol-induced cardiac hypertrophy through regulating the AMPK-related pathway. Acta biochimica et biophysica Sinica. vol 51. issue 1. 2019-05-24. PMID:30566571. |
in the present study, we explored whether adiporon attenuates isoprenaline (iso) or l-thyroxine-induced cardiac hypertrophy in sprague-dawley (sd) rats and whether the anti-hypertrophy effect is mediated by ampk-related pathway. |
2019-05-24 |
2023-08-13 |
rat |
| Jia-Shen Li, Xiao-Yu Zhu, Mei-Li Lu, Jun-Hong Gao, Hong-Xin Wang, Xiao-Chun Y. [Effect of Combined Intervention of Electroacupuncture and Astragaloside IV on Myocardial Hypertrophy and TGF-β 1/Smad Signaling in Rats with Myocardial Fibrosis]. Zhen ci yan jiu = Acupuncture research. vol 42. issue 6. 2019-04-03. PMID:29318851. |
to observe the effect of combined intervention of electroacupuncture (ea) and astragaloside iv(asiv) on cardiac hypertrophy and transforming growth factor β 1 (tgf-β 1)/smad signaling in isoproterenol (iso) induced cardiac hypertrophy rats, so as to investigate its underlying mechanisms in improving myocardial fibrosis. |
2019-04-03 |
2023-08-13 |
rat |
| Sumia A Bageghni, Karen E Hemmings, Ngonidzashe Zava, Christopher P Denton, Karen E Porter, Justin F X Ainscough, Mark J Drinkhill, Neil A Turne. Cardiac fibroblast-specific p38α MAP kinase promotes cardiac hypertrophy via a putative paracrine interleukin-6 signaling mechanism. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 32. issue 9. 2019-03-21. PMID:29601781. |
isoproterenol infusion in control mice promoted overt cardiac hypertrophy and dysfunction (reduced ejection fraction, increased end systolic volume, increased cardiac weight index, increased cardiomyocyte area, increased fibrosis, and up-regulation of myocyte fetal genes and hypertrophy-associated micrornas). |
2019-03-21 |
2023-08-13 |
mouse |