| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R Kumar, S Sharm. Isoproterenol hydrochloride augments collagen proliferation and ATPase activity in mice soleus and EDL muscles. Acta physiologica Hungarica. vol 94. issue 3. 2007-10-04. PMID:17853774. |
isoproterenol resulted in significant increase in muscle weight to whole body weight ratio with no increase in hypertrophy index in soleus muscle. |
2007-10-04 |
2023-08-12 |
mouse |
| Oleg Osadchii, Gavin Norton, Dawn Deftereos, Angela Woodiwis. Rat strain-related differences in myocardial adrenergic tone and the impact on cardiac fibrosis, adrenergic responsiveness and myocardial structure and function. Pharmacological research. vol 55. issue 4. 2007-08-29. PMID:17257851. |
however, increases in myocardial noradrenaline release in sd rats did not translate into enhanced myocardial fibrosis, cardiac hypertrophy or remodeling, changes in basal ventricular systolic and diastolic function, or to down-regulation of inotropic responses to the beta-adrenoreceptor agonists, noradrenaline, isoproterenol and dobutamine. |
2007-08-29 |
2023-08-12 |
rat |
| Yutaka Kitagawa, Yamato Tamura, Juichiro Shimizu, Chikako Nakajima-Takenaka, Shigeki Taniguchi, Shinichi Uesato, Miyako Takak. Effects of a novel histone deacetylase inhibitor, N-(2-aminophenyl) benzamide, on a reversible hypertrophy induced by isoproterenol in in situ rat hearts. Journal of pharmacological sciences. vol 104. issue 2. 2007-08-23. PMID:17558183. |
effects of a novel histone deacetylase inhibitor, n-(2-aminophenyl) benzamide, on a reversible hypertrophy induced by isoproterenol in in situ rat hearts. |
2007-08-23 |
2023-08-12 |
rat |
| Yutaka Kitagawa, Yamato Tamura, Juichiro Shimizu, Chikako Nakajima-Takenaka, Shigeki Taniguchi, Shinichi Uesato, Miyako Takak. Effects of a novel histone deacetylase inhibitor, N-(2-aminophenyl) benzamide, on a reversible hypertrophy induced by isoproterenol in in situ rat hearts. Journal of pharmacological sciences. vol 104. issue 2. 2007-08-23. PMID:17558183. |
the aim of the present study was performed to determine whether a novel histone deacetylase (hdac) inhibitor, n-(2-aminophenyl)-4-{[benzyl(2-hydroxyethyl)amino]methyl} benzamide (k-183), prevents a reversible cardiac hypertrophy induced by isoproterenol and improves left ventricular (lv) dysfunction in rats. |
2007-08-23 |
2023-08-12 |
rat |
| Dan Shan, Hongxin Wang, Yuhong Su, Yang Jing, Tak Ming Won. kappa-opioid receptor stimulation inhibits cardiac hypertrophy induced by beta1-adrenoceptor stimulation in the rat. European journal of pharmacology. vol 555. issue 2-3. 2007-04-04. PMID:17126321. |
to test the hypothesis that kappa-opioid receptor stimulation inhibits cardiac hypertrophy induced by beta1-adrenoceptor stimulation, we determined the effects of trans-(+/-)-3,4-dichloro-n-methyl-n-[2-(1-pyrrolidinyl)-cyclohexyl]-benzeneacetamide methanesulfonate salt (u50,488h), a selective kappa-opioid receptor agonist, on cardiac hypertrophy induced by isoprenaline, a selective beta-adrenoceptor agonist, in neonatal ventricular myocytes upon blockade of beta2-adrenoceptor. |
2007-04-04 |
2023-08-12 |
rat |
| Eric J Jaehnig, Analeah B Heidt, Stephanie B Greene, Ivo Cornelissen, Brian L Blac. Increased susceptibility to isoproterenol-induced cardiac hypertrophy and impaired weight gain in mice lacking the histidine-rich calcium-binding protein. Molecular and cellular biology. vol 26. issue 24. 2007-01-24. PMID:17030629. |
in addition, hrc null mice displayed a significantly exaggerated response to the induction of cardiac hypertrophy by isoproterenol compared to their wild-type littermates. |
2007-01-24 |
2023-08-12 |
mouse |
| Sung-Young Shin, Sang-Mok Choo, Dongsan Kim, Song Joon Baek, Olaf Wolkenhauer, Kwang-Hyun Ch. Switching feedback mechanisms realize the dual role of MCIP in the regulation of calcineurin activity. FEBS letters. vol 580. issue 25. 2006-12-20. PMID:17046757. |
however, it has been shown that mcip facilitates or permits the hypertrophic response under some stress conditions such as isoproterenol infusion or pressure overload by transverse aortic constriction. |
2006-12-20 |
2023-08-12 |
Not clear |
| Geum Shil Hwang, Kwang-Seok Oh, Hyun-Na Koo, Ho Won Seo, Kwan-Hee You, Byung Ho Le. Effects of KR-31378, a novel ATP-sensitive potassium channel activator, on hypertrophy of H9c2 cells and on cardiac dysfunction in rats with congestive heart failure. European journal of pharmacology. vol 540. issue 1-3. 2006-12-11. PMID:16729997. |
in rat heart-derived h9c2 cells treated with hypertrophic agonists, such as angiotensin ii, phenylephrine, isoproterenol, and urotensin ii, cell size was significantly increased by 27-47%. |
2006-12-11 |
2023-08-12 |
rat |
| Nari Kim, Hyunju Kim, Jae Boum Youm, Won Sun Park, Mohamad Warda, Jae-Hong Ko, Jin Ha. Site specific differential activation of ras/raf/ERK signaling in rabbit isoproterenol-induced left ventricular hypertrophy. Biochimica et biophysica acta. vol 1763. issue 10. 2006-12-06. PMID:16987560. |
to understand better the mediating role of ras/raf/erk signaling pathway in development of cardiac hypertrophy and cerebrovascular events in vivo, the molecular mechanism of the pathway in heart and cerebral arteries after isoproterenol (iso) induced beta-adrenergic receptor (betaar) stimulation was examined in rabbit as animal model. |
2006-12-06 |
2023-08-12 |
rabbit |
| Tomohiko Sakatani, Takeshi Shirayama, Taku Yamamoto, Hiroki Mani, Hirokazu Shiraishi, Hiroaki Matsubar. Cardiac hypertrophy diminished the effects of isoproterenol on delayed rectifier potassium current in rat heart. The journal of physiological sciences : JPS. vol 56. issue 2. 2006-10-19. PMID:16839443. |
cardiac hypertrophy diminished the effects of isoproterenol on delayed rectifier potassium current in rat heart. |
2006-10-19 |
2023-08-12 |
rat |
| Tomohiko Sakatani, Takeshi Shirayama, Taku Yamamoto, Hiroki Mani, Hirokazu Shiraishi, Hiroaki Matsubar. Cardiac hypertrophy diminished the effects of isoproterenol on delayed rectifier potassium current in rat heart. The journal of physiological sciences : JPS. vol 56. issue 2. 2006-10-19. PMID:16839443. |
isoproterenol (100 nm)-stimulated i(k) was increased by 54.9% +/- 0.10% in sham-operated rats, but not in hypertrophic rats. |
2006-10-19 |
2023-08-12 |
rat |
| Tomohiko Sakatani, Takeshi Shirayama, Taku Yamamoto, Hiroki Mani, Hirokazu Shiraishi, Hiroaki Matsubar. Cardiac hypertrophy diminished the effects of isoproterenol on delayed rectifier potassium current in rat heart. The journal of physiological sciences : JPS. vol 56. issue 2. 2006-10-19. PMID:16839443. |
on the other hand, isoproterenol increased i(ca) in both sham-operated (77.7% +/- 7.6%) and hypertrophic rats (69.6% +/- 9.7%). |
2006-10-19 |
2023-08-12 |
rat |
| Tomohiko Sakatani, Takeshi Shirayama, Taku Yamamoto, Hiroki Mani, Hirokazu Shiraishi, Hiroaki Matsubar. Cardiac hypertrophy diminished the effects of isoproterenol on delayed rectifier potassium current in rat heart. The journal of physiological sciences : JPS. vol 56. issue 2. 2006-10-19. PMID:16839443. |
consequently, isoproterenol prolonged further apd in hypertrophic rats (98 +/- 11 vs. 145 +/- 8.6 ms, p < 0.01), but not in sham-operated rats (55 +/- 3.9 vs. 61 +/- 5.6 ms, n.s.). |
2006-10-19 |
2023-08-12 |
rat |
| Tomohiko Sakatani, Takeshi Shirayama, Taku Yamamoto, Hiroki Mani, Hirokazu Shiraishi, Hiroaki Matsubar. Cardiac hypertrophy diminished the effects of isoproterenol on delayed rectifier potassium current in rat heart. The journal of physiological sciences : JPS. vol 56. issue 2. 2006-10-19. PMID:16839443. |
we concluded that in hypertrophic hearts, i(k) was not increased by isoproterenol because of the enhanced activity of phosphodiesterase, which leads to excessive apd prolongation. |
2006-10-19 |
2023-08-12 |
rat |
| Chitrang J Trivedi, R Balaraman, Jayesh B Majithiya, Sunil B Bothar. Effect of atorvastatin treatment on isoproterenol-induced myocardial infarction in rats. Pharmacology. vol 77. issue 1. 2006-09-26. PMID:16567950. |
however, it could not reduce oxidative stress and hypertrophy induced by isoproterenol. |
2006-09-26 |
2023-08-12 |
rat |
| Surender S Katoch, Asha Garg, Sushma Sharm. Histological evidences of reparative and regenerative effects of beta-adrenoceptor agonists, clenbuterol and isoproterenol, in denervated rat skeletal muscle. Indian journal of experimental biology. vol 44. issue 6. 2006-08-14. PMID:16784115. |
beta-agonists, clenbuterol (1.2 mg/kg body weight) and isoproterenol (2 mg/kg body weight), administration (daily oral administration; maximum 7 days) to normal innervated rats as well as denervated animals caused muscle hypertrophy. |
2006-08-14 |
2023-08-12 |
rat |
| Rakesh Kumar, Surender S Katoch, Sushma Sharm. Beta-adrenoceptor agonist treatment reverses denervation atrophy with augmentation of collagen proliferation in denervated mice gastrocnemius muscle. Indian journal of experimental biology. vol 44. issue 5. 2006-07-05. PMID:16708889. |
daily oral administration of isoproterenol hydrochloride (60 mg/kg body weight; for 30 days) a beta-receptor agonist to normal innervated and denervated adult male swiss albino mice confirmed its ability to induce skeletal muscle hypertrophy and reverse denervation atrophy respectively. |
2006-07-05 |
2023-08-12 |
mouse |
| Catalin M Filipeanu, Fuguo Zhou, Erin K Fugetta, Guangyu W. Differential regulation of the cell-surface targeting and function of beta- and alpha1-adrenergic receptors by Rab1 GTPase in cardiac myocytes. Molecular pharmacology. vol 69. issue 5. 2006-06-26. PMID:16461589. |
consistent with the effects on receptor cell-surface targeting, rab1 selectively enhanced erk1/2 activation and hypertrophic growth in response to the alpha1-ar agonist phenylephrine but not to the beta-ar agonist isoproterenol. |
2006-06-26 |
2023-08-12 |
rat |
| Oleg Nisenberg, Anthony E Pegg, Patricia A Welsh, Kerry Keefer, Lisa M Shant. Overproduction of cardiac S-adenosylmethionine decarboxylase in transgenic mice. The Biochemical journal. vol 393. issue Pt 1. 2006-03-16. PMID:16153183. |
the alphamhc/adometdc mice did not display an overt cardiac phenotype, but there was an increased cardiac hypertrophy after beta-adrenergic stimulation with isoprenaline ('isoproterenol'), as well as a small increase in spermine content. |
2006-03-16 |
2023-08-12 |
mouse |
| Keiichiro Kizaki, Muneyoshi Okada, Ryoichi Ito, Kazuki Yoshioka, Kazuyoshi Hashizume, Ken-ichiro Mutoh, Yukio Har. Induction of heparanase gene expression in ventricular myocardium of rats with isoproterenol-induced cardiac hypertrophy. Biological & pharmaceutical bulletin. vol 28. issue 12. 2006-03-09. PMID:16327176. |
gene expression of heparanase, matrix metalloproteinases (mmp)-2 and mmp-9 were examined in ventricles after chronic treatment with isoproterenol (iso) induced cardiac hypertrophy in rats. |
2006-03-09 |
2023-08-12 |
rat |