| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J G Csernansky, D E Barnes, E P Bellows, L Lombroz. Interrelationships between plasma homovanillic acid and indices of dopamine turnover in multiple brain areas during haloperidol and saline administration. Life sciences. vol 46. issue 10. 1990-04-26. PMID:2314192. |
interrelationships between plasma homovanillic acid and indices of dopamine turnover in multiple brain areas during haloperidol and saline administration. |
1990-04-26 |
2023-08-11 |
rat |
| J G Csernansky, D E Barnes, E P Bellows, L Lombroz. Interrelationships between plasma homovanillic acid and indices of dopamine turnover in multiple brain areas during haloperidol and saline administration. Life sciences. vol 46. issue 10. 1990-04-26. PMID:2314192. |
haloperidol administration also had a significant effect on the intercorrelation of dopamine (da) concentrations and indices of da turnover across multiple brain areas. |
1990-04-26 |
2023-08-11 |
rat |
| W T Chance, T Foley-Nelson, J L Nelson, J E Fische. Tyrosine loading increases dopamine metabolite concentrations in the brain. Pharmacology, biochemistry, and behavior. vol 35. issue 1. 1990-04-26. PMID:2315359. |
administration of haloperidol (1.5 mg/kg) to rats increased concentrations of dopamine metabolites in the corpus striatum, nucleus accumbens, hypothalamus and amygdala. |
1990-04-26 |
2023-08-11 |
rat |
| W T Chance, T Foley-Nelson, J L Nelson, J E Fische. Tyrosine loading increases dopamine metabolite concentrations in the brain. Pharmacology, biochemistry, and behavior. vol 35. issue 1. 1990-04-26. PMID:2315359. |
therefore, it is concluded that during periods of increased neuronal activity, as induced by haloperidol, tyrosine availability may become a rate-limiting factor in dopamine metabolism. |
1990-04-26 |
2023-08-11 |
rat |
| G C Chiou, B H Li, F Y Chio. Effects of dopamine antagonists injected through vortex veins on intraocular pressure. Journal of ocular pharmacology. vol 5. issue 4. 1990-04-26. PMID:2576433. |
many dopamine antagonists, such as haloperidol, moperone, metoclopramide, trifluperidol, lenperone, and fluoropipamide, lowered the intraocular pressure (iop), whereas a few of them, such as chlofluperol and trifluoperazine, raised the iop. |
1990-04-26 |
2023-08-11 |
rabbit |
| G C Chiou, B H Li, F Y Chio. Effects of dopamine antagonists injected through vortex veins on intraocular pressure. Journal of ocular pharmacology. vol 5. issue 4. 1990-04-26. PMID:2576433. |
the ocular hypertensive effect of dopamine was blocked by haloperidol as expected. |
1990-04-26 |
2023-08-11 |
rabbit |
| G C Chiou, B H Li, F Y Chio. Effects of dopamine antagonists injected through vortex veins on intraocular pressure. Journal of ocular pharmacology. vol 5. issue 4. 1990-04-26. PMID:2576433. |
however, when the hypotension-inducing dopamine agonist, bromocriptine, and antagonist, haloperidol, were combined, the iop remained unchanged. |
1990-04-26 |
2023-08-11 |
rabbit |
| D Ben-Shachar, M B Youdi. Neuroleptic-induced supersensitivity and brain iron: I. Iron deficiency and neuroleptic-induced dopamine D2 receptor supersensitivity. Journal of neurochemistry. vol 54. issue 4. 1990-04-20. PMID:1968955. |
the possibility that neuroleptic-induced dopamine d2 receptor supersensitivity involves an alteration in brain iron content was investigated in nutritionally iron-deficient and control rats chronically treated with haloperidol (5 mg/kg daily for 14 or 21 days). |
1990-04-20 |
2023-08-11 |
rat |
| D Ben-Shachar, M B Youdi. Neuroleptic-induced supersensitivity and brain iron: I. Iron deficiency and neuroleptic-induced dopamine D2 receptor supersensitivity. Journal of neurochemistry. vol 54. issue 4. 1990-04-20. PMID:1968955. |
the ability of chronic haloperidol treatment to prevent the reduction of dopamine d2 receptor number during iron deficiency may be associated with alteration of body iron status. |
1990-04-20 |
2023-08-11 |
rat |
| D Ben-Shachar, M B Youdi. Neuroleptic-induced supersensitivity and brain iron: I. Iron deficiency and neuroleptic-induced dopamine D2 receptor supersensitivity. Journal of neurochemistry. vol 54. issue 4. 1990-04-20. PMID:1968955. |
thus, less iron may result in an increase in free haloperidol available to the dopamine d2 receptor. |
1990-04-20 |
2023-08-11 |
rat |
| J Lappalainen, J Hietala, M Koulu, T Seppälä, B Sjöholm, E Syvälaht. Chronic treatment with SCH 23390 and haloperidol: effects on dopaminergic and serotonergic mechanisms in rat brain. The Journal of pharmacology and experimental therapeutics. vol 252. issue 2. 1990-04-16. PMID:2179533. |
effects of chronic administration (18 days) with sch 23390 (0.1 or 0.5 mg/kg/day s.c.) and haloperidol (1 mg/kg/day s.c.) on dopamine and serotonin synthesis and metabolism in discrete dopaminergic and serotonergic nuclei of rat brain were studied. |
1990-04-16 |
2023-08-11 |
rat |
| J Lappalainen, J Hietala, M Koulu, T Seppälä, B Sjöholm, E Syvälaht. Chronic treatment with SCH 23390 and haloperidol: effects on dopaminergic and serotonergic mechanisms in rat brain. The Journal of pharmacology and experimental therapeutics. vol 252. issue 2. 1990-04-16. PMID:2179533. |
in turn, chronic administration with haloperidol decreased basal dopamine metabolism and synthesis in nucleus caudatus and nucleus accumbens. |
1990-04-16 |
2023-08-11 |
rat |
| J Lappalainen, J Hietala, M Koulu, T Seppälä, B Sjöholm, E Syvälaht. Chronic treatment with SCH 23390 and haloperidol: effects on dopaminergic and serotonergic mechanisms in rat brain. The Journal of pharmacology and experimental therapeutics. vol 252. issue 2. 1990-04-16. PMID:2179533. |
in conclusion, the classical antipsychotic drug, haloperidol, clearly decreases dopamine turnover in nigrostriatal and mesolimbic dopaminergic systems. |
1990-04-16 |
2023-08-11 |
rat |
| J H Pazo, M I Vaccaro, O R Tumilasci, G M Murer, E L Calv. Changes in pancreatic exocrine secretion after repeated haloperidol administration. Journal of the autonomic nervous system. vol 28. issue 3. 1990-04-16. PMID:2576428. |
from these findings it is concluded that repeated haloperidol treatment produces an increase of basal pancreatic secretion, which is probably the result of changes in the sensitivity of dopamine receptors of the gland. |
1990-04-16 |
2023-08-11 |
mouse |
| F M Scalzo, G D Newport, B J Gough, S F Ali, R R Holso. Chronic prenatal haloperidol exposure: lack of effect on presynaptic dopamine autoreceptors. Neurotoxicology. vol 10. issue 3. 1990-04-12. PMID:2516618. |
chronic prenatal haloperidol exposure: lack of effect on presynaptic dopamine autoreceptors. |
1990-04-12 |
2023-08-11 |
rat |
| F M Scalzo, G D Newport, B J Gough, S F Ali, R R Holso. Chronic prenatal haloperidol exposure: lack of effect on presynaptic dopamine autoreceptors. Neurotoxicology. vol 10. issue 3. 1990-04-12. PMID:2516618. |
the effects of prenatal haloperidol exposure on presynaptic dopamine (da) autoreceptor function are not well described. |
1990-04-12 |
2023-08-11 |
rat |
| R W Derlet, T E Albertson, P Ric. The effect of haloperidol in cocaine and amphetamine intoxication. The Journal of emergency medicine. vol 7. issue 6. 1990-04-12. PMID:2625524. |
these data suggest a protective role for the central dopamine blocker haloperidol against death from high-dose amphetamine exposure without reducing the incidence of seizures. |
1990-04-12 |
2023-08-11 |
rat |
| K A Cunningham, J M Lakosk. The interaction of cocaine with serotonin dorsal raphe neurons. Single-unit extracellular recording studies. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 3. issue 1. 1990-04-05. PMID:2137698. |
the putative 5-ht1a autoreceptor antagonist spiperone reversed the cocaine-induced depression of firing rate in 64% of 5-ht neurons tested whereas receptor antagonists for dopamine d2 (haloperidol), 5-ht2 (ketanserin), gamma-aminobutyric acid (picrotoxin) and 5-ht1/beta-adrenergic (propranolol) were ineffective. |
1990-04-05 |
2023-08-11 |
rat |
| G A Gudelsky, S A Berry, H Y Meltze. Actions of typical and atypical antipsychotics on tuberoinfundibular dopamine neurons. Psychopharmacology bulletin. vol 25. issue 3. 1990-04-04. PMID:2576317. |
the activity of tuberoinfundibular dopamine neurons, as judged from the accumulation of dihydroxyphenylalanine (dopa) after the inhibition of decarboxylase activity, was unaltered following the acute administration of the typical antipsychotics haloperidol, cis-flupentixol, chlorpromazine, or fluphenazine. |
1990-04-04 |
2023-08-11 |
Not clear |
| P J Fletcher, M Davie. A pharmacological analysis of the eating response induced by 8-OH-DPAT injected into the dorsal raphé nucleus reveals the involvement of a dopaminergic mechanism. Psychopharmacology. vol 100. issue 2. 1990-03-27. PMID:2137632. |
the ability of peripherally injected spiperone to prevent the eating response to 8-oh-dpat reflects its dopamine blocking activity since haloperidol was an effective antagonist of 8-oh-dpat-eating. |
1990-03-27 |
2023-08-11 |
rat |