| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S O Ogren, L Florvall, H Hall, O Magnusson, K Angeby-Mölle. Neuropharmacological and behavioural properties of remoxipride in the rat. Acta psychiatrica Scandinavica. Supplementum. vol 358. 1990-12-14. PMID:1978483. |
unlike haloperidol and sulpiride, remoxipride has weaker antagonistic effects towards presynaptic dopamine activity compared to its effects on postsynaptically mediated activity. |
1990-12-14 |
2023-08-11 |
rat |
| S O Ogren, L Florvall, H Hall, O Magnusson, K Angeby-Mölle. Neuropharmacological and behavioural properties of remoxipride in the rat. Acta psychiatrica Scandinavica. Supplementum. vol 358. 1990-12-14. PMID:1978483. |
the results suggest that remoxipride, unlike haloperidol, can discriminate between different types of dopamine mediated functions probably by having a preferential action on subpopulations of functionally coupled dopamine d2 receptors. |
1990-12-14 |
2023-08-11 |
rat |
| T Morimoto, Y Morimoto, T Fukuda, M Setoguch. [Effect of Y-516 on the hyperactivity induced by dopamine injected bilaterally into the nucleus accumbens]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. vol 96. issue 2. 1990-12-05. PMID:2227720. |
the effect of y-516 on the hyperactivity induced by dopamine injected bilaterally into the nucleus accumbens was compared with those of clocapramine (ccp), haloperidol (hpd) and chlorpromazine (cpz). |
1990-12-05 |
2023-08-11 |
Not clear |
| S Biswas, M K Podda. Does GABA act through dopaminergic/cholinergic interaction in the regulation of higher environmental temperature-induced change in body temperature? Methods and findings in experimental and clinical pharmacology. vol 12. issue 5. 1990-12-04. PMID:2232964. |
but this potentiating effect remained unaltered when dopamine antagonist haloperidol (1 mg/kg, i.p.) |
1990-12-04 |
2023-08-11 |
rat |
| K Shibata, D M Haverstick, M J Banno. Tachykinin gene expression in rat limbic nuclei: modulation by dopamine antagonists. The Journal of pharmacology and experimental therapeutics. vol 255. issue 1. 1990-11-21. PMID:1976801. |
the prototypical dopamine antagonists haloperidol and chlorpromazine decreased striatal ppt mrna, had no effect on ppt mrna in the nucleus accumbens or bed nucleus of the stria terminalis, and increased septal ppt mrna levels. |
1990-11-21 |
2023-08-11 |
rat |
| R F Gariano, S J Young, D V Jeste, D S Segal, P M Grove. Effects of long-term administration of haloperidol on electrophysiologic properties of rat mesencephalic neurons. The Journal of pharmacology and experimental therapeutics. vol 255. issue 1. 1990-11-21. PMID:2213545. |
no consistent effects of haloperidol administration for 4 weeks or 13 to 14 months were found for either the number of spontaneously active dopamine neurons or their firing rates. |
1990-11-21 |
2023-08-11 |
human |
| J Wolffgramm, H Rommelspacher, E Buc. Ethanol reduces tolerance, sensitization, and up-regulation of D2-receptors after subchronic haloperidol. Pharmacology, biochemistry, and behavior. vol 36. issue 4. 1990-11-14. PMID:2217521. |
to study the interrelationships between dopamine d2-receptor density and behavioral responses after chronic treatment with neuroleptics female wistar rats received haloperidol (hp; 14 mg/l), ethanol (etoh; 5 vol.%), a combination of both, or tap water as drinking fluids for one or two weeks. |
1990-11-14 |
2023-08-11 |
rat |
| I P Lapin, I V Ryzo. Effect of catecholaminergic drugs on quinolinate- and kynurenine-induced seizures in mice. Journal of neural transmission. General section. vol 82. issue 1. 1990-11-01. PMID:2144973. |
dopamine abolished the effect of haloperidol while serotonin was ineffective. |
1990-11-01 |
2023-08-11 |
mouse |
| A Lucchelli, C Boselli, E Gran. Dopamine-induced relaxation of the guinea-pig isolated jejunum is not mediated through dopamine receptors. Pharmacological research. vol 22. issue 4. 1990-10-23. PMID:1976247. |
the effects of the dopamine receptor blockers, haloperidol and cis-alpha-flupenthixol and the da1 selective blocker sch 23390 on the relaxing effect of dopamine were also studied. |
1990-10-23 |
2023-08-11 |
Not clear |
| A Lucchelli, C Boselli, E Gran. Dopamine-induced relaxation of the guinea-pig isolated jejunum is not mediated through dopamine receptors. Pharmacological research. vol 22. issue 4. 1990-10-23. PMID:1976247. |
the relaxing effect of dopamine was not reduced by haloperidol, cis-alpha-flupenthixol and sch 23390. |
1990-10-23 |
2023-08-11 |
Not clear |
| T Kazawa, M Mikuni, T Higuchi, I Arai, K Takahashi, T Yamauch. Characterization of sulpiride-displaceable 3H-YM-09151-2 binding sites in rat frontal cortex and the effects of subchronic treatment with haloperidol on cortical D-2 dopamine receptors. Life sciences. vol 47. issue 6. 1990-10-22. PMID:2402179. |
characterization of sulpiride-displaceable 3h-ym-09151-2 binding sites in rat frontal cortex and the effects of subchronic treatment with haloperidol on cortical d-2 dopamine receptors. |
1990-10-22 |
2023-08-11 |
rat |
| C Humpel, G A Knaus, B Auer, H G Knaus, C Haring, E Theodorsson, A Sari. Effects of haloperidol and clozapine on preprotachykinin-A messenger RNA, tachykinin tissue levels, release and neurokinin-1 receptors in the striato-nigral system. Synapse (New York, N.Y.). vol 6. issue 1. 1990-10-18. PMID:1697986. |
the effects of haloperidol and clozapine on tachykinin tissue levels, preprotachykinin-a messenger rna, spontaneous and potassium-evoked tachykinin release, dopamine d2 receptors, and [125i]bolton-hunter-substance p binding sites in the striato-nigral system were examined. |
1990-10-18 |
2023-08-11 |
Not clear |
| K Ossowska, M Karcz, J Wardas, S Wolfart. Striatal and nucleus accumbens D1/D2 dopamine receptors in neuroleptic catalepsy. European journal of pharmacology. vol 182. issue 2. 1990-10-17. PMID:1975782. |
it is concluded that (1) the catalepsy induced by systemic administration of haloperidol seems to result from the action of this drug on both the ventro-rostral striatum and the nucleus accumbens, (2) both d1 and d2 dopamine receptors in the ventro-rostral striatum are involved in the cataleptogenic action of neuroleptics, and (3) in the nucleus accumbens, only d1 dopamine receptors seem to play an important role in this phenomenon. |
1990-10-17 |
2023-08-11 |
Not clear |
| T Kihara, M Ikeda, A Matsushit. Ceruletide, a cholecystokinin-related peptide, attenuates haloperidol-induced increase in dopamine release from the rat striatum: an in vivo microdialysis study. Brain research. vol 519. issue 1-2. 1990-10-16. PMID:2397417. |
the effects of ceruletide diethylamine (clt), a cholecystokinin (cck)-related peptide, on the spontaneous and haloperidol (hpd)-induced release of striatal dopamine (da) were investigated with the in vivo microdialysis method. |
1990-10-16 |
2023-08-11 |
rat |
| V N Babichev, T A Peryshkova, E I Adamskai. [The dependence of follicle-stimulating hormone secretion on the level of sex hormone receptors in the hypophysis and on the activity of the CNS catecholaminergic systems]. Problemy endokrinologii. vol 36. issue 3. 1990-10-10. PMID:2118637. |
on the contrary, haloperidol (a blocker of dopamine receptors) lowered the level of fsh at 3 o'clock of the estrous stage but made no effect on the blood concentration of lh. |
1990-10-10 |
2023-08-11 |
Not clear |
| Y Cheng, D H Jian. [Therapeutic effect of inosine in Tourette syndrome and its possible mechanism of action]. Zhonghua shen jing jing shen ke za zhi = Chinese journal of neurology and psychiatry. vol 23. issue 2. 1990-10-04. PMID:2390879. |
since we have observed that inosine potentiated the release of dopamine from rat striatal synaptosomes, mimicked the action of some dopamine antagonists, it is suggested that inosine might behave as a dopamine antagonist and exerts its effect on tourette syndrome as haloperidol does. |
1990-10-04 |
2023-08-11 |
rat |
| M R Lynch, R J Care. Chronic low-dose haloperidol effects on self-stimulation rate-intensity functions. Psychopharmacology. vol 102. issue 1. 1990-10-04. PMID:2392500. |
biochemical tolerance to stimulated dopamine metabolism (as per cent non-drug control) was significant only for mesolimbic (versus neostriatal) regions, in animals receiving haloperidol according to pre- and post-test administration schedules. |
1990-10-04 |
2023-08-11 |
Not clear |
| T Watanabe, K Matsuhashi, S Takayam. Placental and blood-brain barrier transfer following prenatal and postnatal exposures to neuroactive drugs: relationship with partition coefficient and behavioral teratogenesis. Toxicology and applied pharmacology. vol 105. issue 1. 1990-10-01. PMID:1975464. |
the logarithms of partition coefficients (log pcorr), used as indices of the lipid solubility of the drugs, decreased in the order propranolol greater than chlorpromazine greater than haloperidol greater than atropine greater than reserpine greater than dopamine greater than epinephrine greater than norepinephrine. |
1990-10-01 |
2023-08-11 |
rat |
| J G Csernansky, E P Bellows, D E Barnes, L Lombroz. Sensitization versus tolerance to the dopamine turnover-elevating effects of haloperidol: the effect of regular/intermittent dosing. Psychopharmacology. vol 101. issue 4. 1990-09-27. PMID:2388975. |
sensitization versus tolerance to the dopamine turnover-elevating effects of haloperidol: the effect of regular/intermittent dosing. |
1990-09-27 |
2023-08-11 |
Not clear |
| A D Baine. Functional effects of proximal tubular dopamine production. American journal of hypertension. vol 3. issue 6 Pt 2. 1990-09-20. PMID:2200436. |
haloperidol and sch 23390 block dopamine excretion, therefore dopamine antagonists may inhibit tubular dopamine responses by lowering intracellular dopamine concentration as well as by receptor blockade. |
1990-09-20 |
2023-08-11 |
Not clear |