| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S Kurosawa, W L Hasler, G Torres, J W Wiley, C Owyan. Characterization of receptors mediating the effects of dopamine on gastric smooth muscle. Gastroenterology. vol 100. issue 5 Pt 1. 1991-05-13. PMID:1672857. |
the alpha-adrenoceptor antagonist phentolamine competitively inhibited dopamine-induced circular contractions (ki = 2.5 x 10(-8) mol/l slope 1.06), whereas the dopamine antagonist haloperidol had no effect. |
1991-05-13 |
2023-08-11 |
Not clear |
| F S Messih. Genetics, haloperidol and pimozide: a comparative study in two mouse strains. Neurotoxicology. vol 12. issue 1. 1991-05-10. PMID:2014068. |
the results suggest a higher turnover of striatal dopamine by haloperidol than by pimozide in the albino balb/c but not in the black c57bl/6 mouse strain which may explain the high incidences of haloperidol-induced extrapyramidal side effects. |
1991-05-10 |
2023-08-11 |
mouse |
| N I Shigaev, D N Lazarev. [The effect of catecholaminergic agents on the efficacy of immunostimulants]. Farmakologiia i toksikologiia. vol 53. issue 6. 1991-05-07. PMID:1981988. |
the influence of combinations of immunostimulants (prodigiosin, methyluracil, levamisole) and catecholaminergic agents (dopamine, haloperidol, noradrenaline, phentolamine, isoproterenol, propranolol) on the results of antibiotic therapy of acute generalized proteus infection and primary immune response to ram erythrocytes was studied on outbred albino mice. |
1991-05-07 |
2023-08-11 |
mouse |
| Y Schmitz, H Wolbur. Gap junction morphology of retinal horizontal cells is sensitive to pH alterations in vitro. Cell and tissue research. vol 263. issue 2. 1991-05-02. PMID:2007254. |
the application of dopamine, which uncouples horizontal cells, and its antagonist haloperidol produce less clear-cut effects on particle density in vitro. |
1991-05-02 |
2023-08-11 |
Not clear |
| M Sasa, M Hara, S Takaor. Dopamine D-1 receptor-mediated inhibition of nucleus accumbens neurons from the ventral tegmental area. Progress in neuro-psychopharmacology & biological psychiatry. vol 15. issue 1. 1991-04-29. PMID:1826178. |
spike generation by stimulation of the parafascicular nucleus of thalamus was extracellularly recorded in the nucleus accumbens of chloral hydrate-anesthetized adult wistar rats using a silver-wire microelectrode attached along a seven-barreled micropipette, each of which was filled with dopamine, skf 38393 (d-1 agonist), bromocriptine (d-2 agonist), haloperidol, sch 23390 (d-1 antagonist) and domperidone (d-2 antagonist). |
1991-04-29 |
2023-08-11 |
rat |
| P J Elliott, J M Paris, H Mitsushio, S A Loren. Neuronal sites mediating locomotor hyperactivity following central neurokinin agonist administration. Pharmacology, biochemistry, and behavior. vol 37. issue 2. 1991-04-26. PMID:1706862. |
however, the hyperactivity following mrn microinjections of dimec7 was attenuated by intraperitoneal administration of the dopamine (da) antagonist, haloperidol. |
1991-04-26 |
2023-08-11 |
Not clear |
| P Bartel, M Blom, E Robinson, C van der Meyden, D K Sommers, P Becke. The effects of levodopa and haloperidol on flash and pattern ERGs and VEPs in normal humans. Documenta ophthalmologica. Advances in ophthalmology. vol 76. issue 1. 1991-04-26. PMID:2078983. |
we investigated the effects of single doses of the dopamine agonist levodopa and the dopamine antagonist haloperidol on pattern and flash electroretinograms (ergs) and visual evoked potentials (veps) in normal subjects. |
1991-04-26 |
2023-08-11 |
human |
| A P Ford, C A Marsde. In vivo neurochemical and behavioural effects of intracerebrally administered neurotensin and D-Trp11-neurotensin on mesolimbic and nigrostriatal dopaminergic function in the rat. Brain research. vol 534. issue 1-2. 1991-04-18. PMID:2073584. |
bilateral application of neurotensin to the nucleus accumbens, like the neuroleptic haloperidol, inhibited the hyperactivity response to the dopamine agonist, n,n-propylnorapomorphine, but, unlike haloperidol, its bilateral intrastriatal application failed to reduce the degree of stereotyped behaviour induced by peripheral apomorphine injection. |
1991-04-18 |
2023-08-11 |
rat |
| K L Drew, W T O'Connor, J Kehr, U Ungersted. Regional specific effects of clozapine and haloperidol on GABA and dopamine release in rat basal ganglia. European journal of pharmacology. vol 187. issue 3. 1991-04-15. PMID:2073921. |
regional specific effects of clozapine and haloperidol on gaba and dopamine release in rat basal ganglia. |
1991-04-15 |
2023-08-11 |
rat |
| K L Drew, W T O'Connor, J Kehr, U Ungersted. Regional specific effects of clozapine and haloperidol on GABA and dopamine release in rat basal ganglia. European journal of pharmacology. vol 187. issue 3. 1991-04-15. PMID:2073921. |
gamma-aminobutyric acid (gaba) and dopamine release were measured concomitantly in rat dorsolateral striatum, fundus striati (a ventral region of striatum) and globus pallidus following s.c. administration of haloperidol or clozapine. |
1991-04-15 |
2023-08-11 |
rat |
| K L Drew, W T O'Connor, J Kehr, U Ungersted. Regional specific effects of clozapine and haloperidol on GABA and dopamine release in rat basal ganglia. European journal of pharmacology. vol 187. issue 3. 1991-04-15. PMID:2073921. |
dopamine release was increased by haloperidol and clozapine in the two regions of the striatum. |
1991-04-15 |
2023-08-11 |
rat |
| K L Drew, W T O'Connor, J Kehr, U Ungersted. Regional specific effects of clozapine and haloperidol on GABA and dopamine release in rat basal ganglia. European journal of pharmacology. vol 187. issue 3. 1991-04-15. PMID:2073921. |
these data suggest that (1) regional differences in the effects of haloperidol and clozapine on gaba release in the basal ganglia may parallel the unique clinical profiles of these drugs; and (2) increases in dopamine release may occur independently of a gabaergic component in the dorsolateral striatum following low doses of haloperidol and clozapine and in the fundus striati following all effective doses of haloperidol. |
1991-04-15 |
2023-08-11 |
rat |
| F S Messih. Differential modulation of mouse brain biogenic amines by haloperidol and pimozide: implications in Tourette's syndrome. Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology. vol 97. issue 1. 1991-04-09. PMID:1981344. |
haloperidol was more potent than pimozide in altering striatal dopamine concentration which may account for the greater incidence of haloperidol-induced extrapyramidal disorders compared to pimozide. |
1991-04-09 |
2023-08-11 |
mouse |
| H Coirini, M Schumacher, J A Angulo, B S McEwe. Increase in striatal dopamine D2 receptor mRNA after lesions of haloperidol treatment. European journal of pharmacology. vol 186. issue 2-3. 1991-04-03. PMID:2127022. |
increase in striatal dopamine d2 receptor mrna after lesions of haloperidol treatment. |
1991-04-03 |
2023-08-11 |
Not clear |
| V Dietz, T J Feuerstein, W Berge. Significance of dopamine receptor antagonists in human postural control. Neuroscience letters. vol 117. issue 1-2. 1991-04-01. PMID:2290625. |
haloperidol as preferential d2 and the 'pure' dopamine d2 receptor antagonist sulpiride significantly reduced the level of the reflex response in the gastrocnemius muscle following backward perturbation. |
1991-04-01 |
2023-08-11 |
human |
| L Giardino, L Calzà, P V Piazza, M Zanni, G Amat. DA2/NT receptor balance in the mesostriatal and mesolimbocortical systems after chronic treatment with typical and atypical neuroleptic drugs. Brain research. vol 532. issue 1-2. 1991-03-21. PMID:1980851. |
because of the interaction between dopamine (da) and neurotensin (nt) in the target areas of these systems, and in order to study if the different action of typical and atypical neuroleptic drugs could be related to a modification of the da/nt balance, we investigated da2 and nt receptor modifications--by means of quantitative receptor autoradiography--after chronic treatment with low dosage of haloperidol, chlorpromazine, thioridazine and clozapine. |
1991-03-21 |
2023-08-11 |
Not clear |
| L Peacock, H Lublin, J Gerlac. The effects of dopamine D1 and D2 receptor agonists and antagonists in monkeys withdrawn from long-term neuroleptic treatment. European journal of pharmacology. vol 186. issue 1. 1991-03-15. PMID:1980891. |
the effects of dopamine d1 and d2 receptor agonists and antagonists were studied in eight cebus apella monkeys previously treated with haloperidol for two years. |
1991-03-15 |
2023-08-11 |
monkey |
| L K Srivastava, M A Morency, S B Bajwa, R K Mishr. Effect of haloperidol on expression of dopamine D2 receptor mRNAs in rat brain. Journal of molecular neuroscience : MN. vol 2. issue 3. 1991-03-06. PMID:1703431. |
effect of haloperidol on expression of dopamine d2 receptor mrnas in rat brain. |
1991-03-06 |
2023-08-11 |
rat |
| L K Srivastava, M A Morency, S B Bajwa, R K Mishr. Effect of haloperidol on expression of dopamine D2 receptor mRNAs in rat brain. Journal of molecular neuroscience : MN. vol 2. issue 3. 1991-03-06. PMID:1703431. |
chronic administration of the neuroleptic drug haloperidol previously has been shown to increase the density of striatal dopamine d2 receptor, which is believed to be the underlying factor in neuroleptic-induced tardive dyskinesia. |
1991-03-06 |
2023-08-11 |
rat |
| D J Wiedemann, A Basse-Tomusk, R L Wilson, G V Rebec, R M Wightma. Interference by DOPAC and ascorbate during attempts to measure drug-induced changes in neostriatal dopamine with Nafion-coated, carbon-fiber electrodes. Journal of neuroscience methods. vol 35. issue 1. 1991-03-06. PMID:2148961. |
administration of haloperidol (0.5 mg kg-1) followed by gbr 12909 (20 mg kg-1), which is known to cause a 10-fold increase in extracellular dopamine, failed to produce a selective signal for dopamine when measured voltammetrically. |
1991-03-06 |
2023-08-11 |
rat |