| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A J Bean, R H Rot. Effects of haloperidol administration on in vivo extracellular dopamine in striatum and prefrontal cortex after partial dopamine lesions. Brain research. vol 549. issue 1. 1991-10-24. PMID:1909923. |
the effects of haloperidol on striatal and prefrontal cortical extracellular fluid dopamine (da) concentrations were examined in sham-operated control rats and in rats which had received partial lesions of their dopamine systems. |
1991-10-24 |
2023-08-11 |
rat |
| F Rodriguez, T Joli. The role of somatostatin and/or dopamine in basal and TRH-stimulated TSH release in food-restricted rats. Acta endocrinologica. vol 125. issue 2. 1991-10-23. PMID:1680265. |
intravenous injections of the dopamine antagonists, domperidone or haloperidol, failed to affect the magnitude of the differences in plasma tsh and gh levels among control and food-restricted groups, indicating that dopaminergic mechanisms had little effect on the regulation of tsh and gh secretion during restricted feeding in rats. |
1991-10-23 |
2023-08-11 |
rat |
| M Diana, S J Young, P M Grove. Modulation of dopaminergic terminal excitability by D1 selective agents: further characterization. Neuroscience. vol 42. issue 2. 1991-10-21. PMID:1680226. |
further, haloperidol pretreatment also prevents the sch 23390-induced decrease in terminal excitability, confirming that dopamine, acting through a dopamine receptor, is responsible for this agonist-like action. |
1991-10-21 |
2023-08-11 |
rat |
| J Bergman, B K Madras, R D Spealma. Behavioral effects of D1 and D2 dopamine receptor antagonists in squirrel monkeys. The Journal of pharmacology and experimental therapeutics. vol 258. issue 3. 1991-10-17. PMID:1890625. |
d2-selective antagonists included cis-n-(1-benzyl-2-methylpyrrolidine-3-yl)-5-chloro-2-methoxy-4- methylaminobenzamide, ym-09151-2, eticlopride, raclopride, haloperidol, risperidone, remoxipride, s-sulpiride and r-sulpiride; nonselective dopamine antagonists were s-butaclamol and chlorpromazine. |
1991-10-17 |
2023-08-11 |
monkey |
| G Pelletier, J Simar. Dopaminergic regulation of pre-proNPY mRNA levels in the rat arcuate nucleus. Neuroscience letters. vol 127. issue 1. 1991-09-30. PMID:1679226. |
in order to study the role of dopamine on neuropeptide y (npy) gene expression in the rat arcuate nucleus, we evaluated the effects of haloperidol, a dopaminergic antagonist, and bromocriptine, a d2 dopamine receptor agonist, on the levels of pre-pronpy mrna as measured by in situ hybridization. |
1991-09-30 |
2023-08-11 |
rat |
| M S Desole, M Miele, P Enrico, G Esposito, L Fresu, G De Natale, E Miel. Investigations into the relationship between the dopaminergic system and ascorbic acid in rat striatum. Neuroscience letters. vol 127. issue 1. 1991-09-30. PMID:1881615. |
levels of dopamine (da), 3,4-dihydroxyphenylacetic acid (dopac), ascorbic acid (aa) and dehydroascorbic acid (dhaa) were determined by hplc in the striatum of male wistar rats after single or repeated injections of apomorphine (1 mg/kg/day s.c.) and/or haloperidol (1 mg/kg/day i.p. |
1991-09-30 |
2023-08-11 |
rat |
| B A Ellenbroek, M T Artz, A R Cool. The involvement of dopamine D1 and D2 receptors in the effects of the classical neuroleptic haloperidol and the atypical neuroleptic clozapine. European journal of pharmacology. vol 196. issue 1. 1991-09-26. PMID:1678712. |
the involvement of dopamine d1 and d2 receptors in the effects of the classical neuroleptic haloperidol and the atypical neuroleptic clozapine. |
1991-09-26 |
2023-08-11 |
Not clear |
| B A Ellenbroek, M T Artz, A R Cool. The involvement of dopamine D1 and D2 receptors in the effects of the classical neuroleptic haloperidol and the atypical neuroleptic clozapine. European journal of pharmacology. vol 196. issue 1. 1991-09-26. PMID:1678712. |
the present results show that the effects of haloperidol in the paw test are antagonised by a dopamine d2 agonist but not by a d1 agonist, whereas the effects of clozapine are reversed by a d1 agonist but not by a d2 agonist. |
1991-09-26 |
2023-08-11 |
Not clear |
| B A Ellenbroek, M T Artz, A R Cool. The involvement of dopamine D1 and D2 receptors in the effects of the classical neuroleptic haloperidol and the atypical neuroleptic clozapine. European journal of pharmacology. vol 196. issue 1. 1991-09-26. PMID:1678712. |
these data suggest that haloperidol produces its therapeutic and extrapyramidal side effects via blockade of dopamine d2 receptors, whereas clozapine produces its therapeutic effects via blockade of dopamine d1 receptors. |
1991-09-26 |
2023-08-11 |
Not clear |
| W A Corrigall, K M Coe. Selective dopamine antagonists reduce nicotine self-administration. Psychopharmacology. vol 104. issue 2. 1991-09-26. PMID:1876661. |
the effects of selective d1 (sch23390) and d2 (spiperone) dopamine antagonists, as well as of haloperidol, were examined on nicotine self-administration, food-maintained responding, and locomotor activity in rats. |
1991-09-26 |
2023-08-11 |
rat |
| E C Essig, I C Kilpatric. Influence of acute and chronic haloperidol treatment on dopamine metabolism in the rat caudate-putamen, prefrontal cortex and amygdala. Psychopharmacology. vol 104. issue 2. 1991-09-26. PMID:1876664. |
influence of acute and chronic haloperidol treatment on dopamine metabolism in the rat caudate-putamen, prefrontal cortex and amygdala. |
1991-09-26 |
2023-08-11 |
rat |
| E C Essig, I C Kilpatric. Influence of acute and chronic haloperidol treatment on dopamine metabolism in the rat caudate-putamen, prefrontal cortex and amygdala. Psychopharmacology. vol 104. issue 2. 1991-09-26. PMID:1876664. |
the present study investigated the actions of single and repeated injections of the classical antipsychotic drug, haloperidol (1 mg.kg-1 ip), on dopamine (da) metabolism in three distinct rat brain regions, namely the prefrontal cortex, amygdala and caudate-putamen (cp), using a high-performance liquid chromatographic assay. |
1991-09-26 |
2023-08-11 |
rat |
| I I Abramets, I M Samoĭlovic. [Reciprocal modulating effect of serotonin and dopamine on neurons of rat spinal ganglia]. Neirofiziologiia = Neurophysiology. vol 23. issue 2. 1991-09-20. PMID:1876209. |
potentiating action of monoamines on combined neuronal responses depended on concentration and was inhibited by antagonists of dopamine (haloperidol) and 5-hydroxytryptamine (deseril) receptors. |
1991-09-20 |
2023-08-11 |
rat |
| A A Mustaf. Bromocriptine-induced hypothermia in Balb/C mice: its possible mechanism of action. General pharmacology. vol 22. issue 3. 1991-09-17. PMID:1651267. |
pretreatment with the dopamine (da) receptor antagonists haloperidol (0.02 mg/kg, i.p.) |
1991-09-17 |
2023-08-11 |
mouse |
| M S Lawrence, D E Redmon. MPTP lesions and dopaminergic drugs alter eye blink rate in African green monkeys. Pharmacology, biochemistry, and behavior. vol 38. issue 4. 1991-09-16. PMID:1678527. |
apomorphine and haloperidol, although less specific, had potent and predictable effects based on their interactions with dopamine systems. |
1991-09-16 |
2023-08-11 |
monkey |
| D R Bull, M J Sheeha. Presynaptic regulation of electrically evoked dopamine overflow in nucleus accumbens: a pharmacological study using fast cyclic voltammetry in vitro. Naunyn-Schmiedeberg's archives of pharmacology. vol 343. issue 3. 1991-09-12. PMID:1678139. |
however, the dopamine d2 receptor agonist, quinpirole, was capable of totally inhibiting the release; this effect was concentration-dependently antagonized by the d2 antagonists haloperidol, sulpiride, metoclopramide and clozapine, with potencies which corresponded to their affinities for d2 receptors in striatal tissue. |
1991-09-12 |
2023-08-11 |
rat |
| F Trent, J M Teppe. Dorsal raphé stimulation modifies striatal-evoked antidromic invasion of nigral dopaminergic neurons in vivo. Experimental brain research. vol 84. issue 3. 1991-09-11. PMID:1830848. |
the dopamine antagonists haloperidol (25-100 micrograms/kg, i.v.) |
1991-09-11 |
2023-08-11 |
rat |
| T Huo, D P Heal. [3H]domperidone binding to the kidney inner medullary collecting duct dopamine-2K (DA2K) receptor. The Journal of pharmacology and experimental therapeutics. vol 258. issue 2. 1991-09-11. PMID:1830902. |
dopaminergic drugs were less potent competitors for [3h]domperidone binding in imcd cells than previously reported for brain da receptors, but the rank order was consistent with the labeling of a da receptor [antagonists: domperidone greater than spiperone greater than haloperidol greater than sch 23390 much greater than (-)-sulpiride; agonists: norapomorphine greater than fenoldopam much greater than dopamine = quinpirole], and was better correlated with the pharmacological profile for the brain d2 receptor than the brain d3 receptor. |
1991-09-11 |
2023-08-11 |
Not clear |
| T Yamada, K Hirayama, H Kimur. Differential responses of noradrenaline and dopamine neurons in the mouse forebrain induced by continuous parenteral infusion of haloperidol. European neurology. vol 31 Suppl 1. 1991-08-23. PMID:1649756. |
differential responses of noradrenaline and dopamine neurons in the mouse forebrain induced by continuous parenteral infusion of haloperidol. |
1991-08-23 |
2023-08-11 |
mouse |
| E von Borell, J F Hurni. The effect of haloperidol on the performance of stereotyped behavior in sows. Life sciences. vol 49. issue 4. 1991-08-20. PMID:2072819. |
the results indicate that dopamine is involved in the performance of stereotypies in pigs, and that haloperidol seem to impair motivational arousal primarily by reducing the rewarding impact of stereotyped self-stimulation. |
1991-08-20 |
2023-08-11 |
Not clear |