| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J H Kehne, T C McCloskey, V L Taylor, C K Black, G M Fadayel, C J Schmid. Effects of the serotonin releasers 3,4-methylenedioxymethamphetamine (MDMA), 4-chloroamphetamine (PCA) and fenfluramine on acoustic and tactile startle reflexes in rats. The Journal of pharmacology and experimental therapeutics. vol 260. issue 1. 1992-02-18. PMID:1731054. |
mdma excitation was not affected by a dose of the dopamine antagonist haloperidol that attenuated the startle-enhancing effect of d-amphetamine. |
1992-02-18 |
2023-08-11 |
rat |
| N Sato, X B Wang, M A Gree. Dopamine inhibits cell swelling-induced prolactin secretion in MMQ cells by blocking Ca2+ influx. Molecular and cellular endocrinology. vol 82. issue 1. 1992-02-12. PMID:1662167. |
this effect of dopamine was prevented by haloperidol. |
1992-02-12 |
2023-08-11 |
rat |
| R E Roudebush, P L Berry, N K Layman, L D Butler, H U Bryan. Dissociation of immunosuppression by chlorpromazine and trifluoperazine from pharmacologic activities as dopamine antagonists. International journal of immunopharmacology. vol 13. issue 7. 1992-02-07. PMID:1684786. |
sulpiride, metoclopramide, and haloperidol) do not share the immunologic profiles of chlorpromazine and trifluoperazine, suggesting that these effects of chlorpromazine and trifluoperazine are not related to their dopamine antagonist properties. |
1992-02-07 |
2023-08-11 |
Not clear |
| R C Pierce, J K Rowlett, M T Bardo, G V Rebe. Chronic ascorbate potentiates the effects of chronic haloperidol on behavioral supersensitivity but not D2 dopamine receptor binding. Neuroscience. vol 45. issue 2. 1992-02-07. PMID:1762684. |
our results indicate that when challenged with the dopamine agonist, apomorphine (0.5 mg/kg), animals chronically treated with haloperidol or high-dose ascorbate alone display a supersensitive sniffing response relative to controls, while animals chronically treated with the combination of haloperidol and high-dose ascorbate display a further potentiation of sniffing relative to the haloperidol groups. |
1992-02-07 |
2023-08-11 |
rat |
| R C Pierce, J K Rowlett, M T Bardo, G V Rebe. Chronic ascorbate potentiates the effects of chronic haloperidol on behavioral supersensitivity but not D2 dopamine receptor binding. Neuroscience. vol 45. issue 2. 1992-02-07. PMID:1762684. |
in addition, [3h]spiperone saturation studies showed, as expected, an up-regulation of striatal d2 dopamine receptors in rats treated with haloperidol as reflected by a change in receptor density (bmax) but not affinity (kd). |
1992-02-07 |
2023-08-11 |
rat |
| R C Pierce, J K Rowlett, M T Bardo, G V Rebe. Chronic ascorbate potentiates the effects of chronic haloperidol on behavioral supersensitivity but not D2 dopamine receptor binding. Neuroscience. vol 45. issue 2. 1992-02-07. PMID:1762684. |
even though chronic treatment with the haloperidol-high-dose-ascorbate combination produced an up-regulation of striatal d2 dopamine receptors, this treatment did not cause a further up-regulation relative to haloperidol alone nor did it have any effect on [3h]apomorphine distribution. |
1992-02-07 |
2023-08-11 |
rat |
| J A Angulo, H Coirini, M Ledoux, M Schumache. Regulation by dopaminergic neurotransmission of dopamine D2 mRNA and receptor levels in the striatum and nucleus accumbens of the rat. Brain research. Molecular brain research. vol 11. issue 2. 1992-02-06. PMID:1661813. |
the time course of pharmacological blockade with haloperidol demonstrates a complex mode of regulation of dopamine d2 mrna and receptor levels. |
1992-02-06 |
2023-08-11 |
rat |
| L R Brougham, P G Conway, D B Elli. Effect of ritanserin on the interaction of amfonelic acid and neuroleptic-induced striatal dopamine metabolism. Neuropharmacology. vol 30. issue 10. 1992-02-04. PMID:1684649. |
in the present study we evaluated the interaction of amfonelic acid (afa) with the typical neuroleptic haloperidol and the atypical antipsychotic clozapine on rat striatal dopamine metabolism in the absence or presence of the 5ht2 receptor antagonist ritanserin. |
1992-02-04 |
2023-08-11 |
rat |
| L R Brougham, P G Conway, D B Elli. Effect of ritanserin on the interaction of amfonelic acid and neuroleptic-induced striatal dopamine metabolism. Neuropharmacology. vol 30. issue 10. 1992-02-04. PMID:1684649. |
to test this, we combined ritanserin with haloperidol and again studied the interaction with afa on dopamine metabolism. |
1992-02-04 |
2023-08-11 |
rat |
| P J Wellma. Overview of adrenergic anorectic agents. The American journal of clinical nutrition. vol 55. issue 1 Suppl. 1992-02-03. PMID:1309478. |
moreover, ppa anorexia is not reversed by the dopamine antagonist haloperidol. |
1992-02-03 |
2023-08-11 |
Not clear |
| V Bernard, C Le Moine, B Bloc. Striatal neurons express increased level of dopamine D2 receptor mRNA in response to haloperidol treatment: a quantitative in situ hybridization study. Neuroscience. vol 45. issue 1. 1992-01-24. PMID:1754061. |
striatal neurons express increased level of dopamine d2 receptor mrna in response to haloperidol treatment: a quantitative in situ hybridization study. |
1992-01-24 |
2023-08-11 |
rat |
| V Bernard, C Le Moine, B Bloc. Striatal neurons express increased level of dopamine D2 receptor mRNA in response to haloperidol treatment: a quantitative in situ hybridization study. Neuroscience. vol 45. issue 1. 1992-01-24. PMID:1754061. |
these results demonstrate that haloperidol treatment acts at the gene level to modulate d2 receptor content in striatal dopaminoceptive neurons, and that the d2 receptor mrna increase in postsynaptic neurons contributes to dopamine supersensitivity induced by neuroleptics in the rat. |
1992-01-24 |
2023-08-11 |
rat |
| R E Se. Striatal dopamine metabolism increases during long-term haloperidol administration in rats but shows tolerance in response to acute challenge with raclopride. Neuroscience letters. vol 129. issue 2. 1992-01-14. PMID:1720879. |
striatal dopamine metabolism increases during long-term haloperidol administration in rats but shows tolerance in response to acute challenge with raclopride. |
1992-01-14 |
2023-08-11 |
rat |
| R E Se. Striatal dopamine metabolism increases during long-term haloperidol administration in rats but shows tolerance in response to acute challenge with raclopride. Neuroscience letters. vol 129. issue 2. 1992-01-14. PMID:1720879. |
the release and metabolism of dopamine (da) in the striatum of rats during long-term haloperidol administration (32 weeks) was assessed using in vivo microdialysis. |
1992-01-14 |
2023-08-11 |
rat |
| N D Karanjia, A L Widdison, F J Lutrin, Y B Chang, H A Rebe. The antiinflammatory effect of dopamine in alcoholic hemorrhagic pancreatitis in cats. Studies on the receptors and mechanisms of action. Gastroenterology. vol 101. issue 6. 1992-01-02. PMID:1659548. |
in the first study, dopamine's antiinflammatory effect on the pancreas was determined in the presence of haloperidol, propranolol, or both. |
1992-01-02 |
2023-08-11 |
Not clear |
| M P DeNinno, R Schoenleber, R MacKenzie, D R Britton, K E Asin, C Briggs, J M Trugman, M Ackerman, L Artman, L Bednar. A68930: a potent agonist selective for the dopamine D1 receptor. European journal of pharmacology. vol 199. issue 2. 1991-12-30. PMID:1683288. |
when tested in rats bearing a unilateral 6-ohda lesion of the nigro-neostriatal neurons, a68930 elicits prolonged (greater than 20 h) contralateral turning that is antagonized by dopamine d1 receptor selective doses of sch 23390 but not by d2 receptor selective doses of haloperidol. |
1991-12-30 |
2023-08-11 |
rat |
| M F Egan, F Karoum, R J Wyat. Effects of acute and chronic clozapine and haloperidol administration on 3-methoxytyramine accumulation in rat prefrontal cortex, nucleus accumbens and striatum. European journal of pharmacology. vol 199. issue 2. 1991-12-30. PMID:1954977. |
the accumulation of 3-methoxytyramine (3-mt), a reflection of dopamine release, was measured in the prefrontal cortex, nucleus accumbens, and striatum following administration of acute and chronic clozapine and haloperidol. |
1991-12-30 |
2023-08-11 |
rat |
| M Doherty, A Gratto. Behavioral evidence of depolarization block of mesencephalic dopamine neurons by acute haloperidol in partially 6-hydroxydopamine-lesioned rats. Behavioral neuroscience. vol 105. issue 4. 1991-12-26. PMID:1657033. |
behavioral evidence of depolarization block of mesencephalic dopamine neurons by acute haloperidol in partially 6-hydroxydopamine-lesioned rats. |
1991-12-26 |
2023-08-11 |
rat |
| M Doherty, A Gratto. Behavioral evidence of depolarization block of mesencephalic dopamine neurons by acute haloperidol in partially 6-hydroxydopamine-lesioned rats. Behavioral neuroscience. vol 105. issue 4. 1991-12-26. PMID:1657033. |
the effects of acute haloperidol (hal) and apomorphine (apo) administration were tested on the responsiveness of rats to medial forebrain bundle (mfb) brain stimulation reward (bsr) before and 28 days after partial dopamine (da) depletion. |
1991-12-26 |
2023-08-11 |
rat |
| V A Keith, R S Mansbach, M A Geye. Failure of haloperidol to block the effects of phencyclidine and dizocilpine on prepulse inhibition of startle. Biological psychiatry. vol 30. issue 6. 1991-12-26. PMID:1834231. |
in rats, ppi is blocked by dopamine agonists such as apomorphine or quinpirole, effects that are antagonized by haloperidol. |
1991-12-26 |
2023-08-11 |
rat |