| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| D J Wiedemann, P A Garris, J A Near, R M Wightma. Effect of chronic haloperidol treatment on stimulated synaptic overflow of dopamine in the rat striatum. The Journal of pharmacology and experimental therapeutics. vol 261. issue 2. 1992-06-05. PMID:1533666. |
effect of chronic haloperidol treatment on stimulated synaptic overflow of dopamine in the rat striatum. |
1992-06-05 |
2023-08-11 |
rat |
| D J Wiedemann, P A Garris, J A Near, R M Wightma. Effect of chronic haloperidol treatment on stimulated synaptic overflow of dopamine in the rat striatum. The Journal of pharmacology and experimental therapeutics. vol 261. issue 2. 1992-06-05. PMID:1533666. |
in vivo voltammetry was used to assess the change in stimulated striatal dopamine overflow in response to various treatments with the dopamine receptor antagonist haloperidol. |
1992-06-05 |
2023-08-11 |
rat |
| D J Wiedemann, P A Garris, J A Near, R M Wightma. Effect of chronic haloperidol treatment on stimulated synaptic overflow of dopamine in the rat striatum. The Journal of pharmacology and experimental therapeutics. vol 261. issue 2. 1992-06-05. PMID:1533666. |
administered to the animals treated with chronic haloperidol did not elicit a change in stimulated dopamine overflow. |
1992-06-05 |
2023-08-11 |
rat |
| D J Wiedemann, P A Garris, J A Near, R M Wightma. Effect of chronic haloperidol treatment on stimulated synaptic overflow of dopamine in the rat striatum. The Journal of pharmacology and experimental therapeutics. vol 261. issue 2. 1992-06-05. PMID:1533666. |
thus, chronic treatment with haloperidol induces long-lasting effects on the capacity of dopamine receptors to modulate dopamine release. |
1992-06-05 |
2023-08-11 |
rat |
| C M Palmeira, C R Oliveir. Partitioning and membrane disordering effects of dopamine antagonists: influence of lipid peroxidation, temperature, and drug concentration. Archives of biochemistry and biophysics. vol 295. issue 1. 1992-06-02. PMID:1575512. |
the effect of four dopamine antagonists (spiperone, haloperidol, pimozide, and domperidone) on the lipid order of caudate nucleus microsomal membranes and on liposomes from membrane lipid extracts was evaluated and related to the partition coefficients (kp) of the drugs. |
1992-06-02 |
2023-08-11 |
Not clear |
| H Fujiwar. Comparative studies of sulpiride and classical neuroleptics on induction of catalepsy, locomotor activity, and brain dopamine metabolism in mice. Pharmacology, biochemistry, and behavior. vol 41. issue 2. 1992-05-29. PMID:1349435. |
subsequently, in the dopamine metabolism, sulpiride, pimozide, and haloperidol: 1) considerably accelerated the turnover in the dopamine metabolism in three distinct brain areas; 2) increased the levels of the dopac, hva, and 3-mt even 6 h after administration, as well as at 1.5 h after administration; and 3) decreased the levels of dopamine in the nucleus accumbens at 1.5 h after administration. |
1992-05-29 |
2023-08-11 |
mouse |
| H Fujiwar. Comparative studies of sulpiride and classical neuroleptics on induction of catalepsy, locomotor activity, and brain dopamine metabolism in mice. Pharmacology, biochemistry, and behavior. vol 41. issue 2. 1992-05-29. PMID:1349435. |
these results indicate that sulpiride displays a mode of action different from pimozide and haloperidol with regard to the induction of catalepsy, but not with regard to the locomotion and brain dopamine metabolism. |
1992-05-29 |
2023-08-11 |
mouse |
| H J Hapke, C Höl. [Effects of dopamine on the coronary vessels of swine]. DTW. Deutsche tierarztliche Wochenschrift. vol 99. issue 2. 1992-05-13. PMID:1559463. |
phentolamine and propranolol were used as adrenergic alpha- und beta-blockers, azaperone and haloperidol were used as unspecific antagonists, and domperidone as a specific dopamine antagonist. |
1992-05-13 |
2023-08-11 |
Not clear |
| H J Hapke, C Höl. [Effects of dopamine on the coronary vessels of swine]. DTW. Deutsche tierarztliche Wochenschrift. vol 99. issue 2. 1992-05-13. PMID:1559463. |
the coronary effects of dopamine in shock therapy are reduced after a treatment of the animals with butyrophenone derivatives like azaperone or haloperidol or after treatment with the specific dopamine antagonist domperidone. |
1992-05-13 |
2023-08-11 |
Not clear |
| M Irifune, T Shimizu, M Nomot. Ketamine-induced hyperlocomotion associated with alteration of presynaptic components of dopamine neurons in the nucleus accumbens of mice. Pharmacology, biochemistry, and behavior. vol 40. issue 2. 1992-05-04. PMID:1805243. |
the hyperactivities induced by both low and high doses of ketamine were inhibited by a low dose of haloperidol (0.10 mg/kg, ip), a dopamine (da) receptor antagonist. |
1992-05-04 |
2023-08-11 |
mouse |
| D Duterte-Boucher, F Duhamel, J Costenti. Dopaminergic transmission and (+)amphetamine-induced lethality in aggregated mice. Fundamental & clinical pharmacology. vol 6. issue 1. 1992-05-01. PMID:1555808. |
the dopamine antagonists haloperidol and alpha-flupenthixol, less specific as regards d1 vs d2 receptors, had an id50 of 66 and 186 micrograms/kg respectively. |
1992-05-01 |
2023-08-11 |
mouse |
| J E Leysen, P M Janssen, W Gommeren, J Wynants, P J Pauwels, P A Jansse. In vitro and in vivo receptor binding and effects on monoamine turnover in rat brain regions of the novel antipsychotics risperidone and ocaperidone. Molecular pharmacology. vol 41. issue 3. 1992-04-16. PMID:1372084. |
ocaperidone, risperidone, and haloperidol readily increased the levels of the dopamine metabolites 3,4-dihydroxybenzene acetic acid and homovanillic acid in the striatum, the nucleus accumbens, the tuberculum olfactorium, and, to some extent, the frontal cortex. |
1992-04-16 |
2023-08-11 |
human |
| P Seeman, J M Schau. Dopamine receptors labelled by [3H]quinpirole. European journal of pharmacology. vol 203. issue 1. 1992-04-16. PMID:1686763. |
however, since the spiperone and haloperidol ki values against [3h]quinpirole were the same as their values at dopamine d2 receptors rather than dopamine d3 receptors, it appears that [3h]quinpirole predominantly labels dopamine d2 receptors in the canine striatum. |
1992-04-16 |
2023-08-11 |
Not clear |
| D Clark, L J Furmidge, N Petry, Z Y Tong, M Ericsson, D Johnso. Behavioural profile of partial D2 dopamine receptor agonists. 1. Atypical inhibition of d-amphetamine-induced locomotor hyperactivity and stereotypy. Psychopharmacology. vol 105. issue 3. 1992-04-13. PMID:1686815. |
the effects of partial d2 dopamine (da) receptor agonists on the behavioural activation produced by 1.5 and 8.0 mg/kg d-amphetamine were compared with the changes produced by the classical da antagonist haloperidol. |
1992-04-13 |
2023-08-11 |
rat |
| P J Bren. Similar behavioural effects of sigma agonists and PCP-like non-competitive NMDA antagonists in guinea-pigs. Psychopharmacology. vol 105. issue 3. 1992-04-13. PMID:1686818. |
the behavioural effects produced by (+) and (-)nanm were not reversed by injection 1 h later of naloxone hydrochloride (15 mg/kg sc), haloperidol (10 mg/kg sc) or dtg (10 and 30 mg/kg sc), but the effects of all drugs were reversed by the selective dopamine d-2 agonist quinpirole (3 mg/kg ip). |
1992-04-13 |
2023-08-11 |
Not clear |
| M R Lync. Behavioral evidence for dopamine receptor subsensitivity following chronic haloperidol. Neuropsychobiology. vol 24. issue 2. 1992-04-13. PMID:2151972. |
this haloperidol treatment was subthreshold for inducing either dopamine autoreceptor supersensitivity or postsynaptic supersensitivity as evidenced by equivalent metabolic reductions in chronically treated neuroleptic versus vehicle groups, and an absence of stereotypical responding in either condition. |
1992-04-13 |
2023-08-11 |
rat |
| K K Maitra, P Seth, K P Mohanakumar, D K Gangul. Supersensitivity of spinal dopaminergic receptors in rat after chronic haloperidol. Brain research bulletin. vol 28. issue 1. 1992-04-09. PMID:1540840. |
in order to examine the effect of chronic neuroleptics on spinal dopaminergic system, rats were treated with haloperidol (0.5 mg/kg ip) for 21 days and the monosynaptic mass reflex (mmr) as well as dopamine (da) metabolism were investigated. |
1992-04-09 |
2023-08-11 |
rat |
| D S Zah. Subsets of neurotensin-immunoreactive neurons revealed following antagonism of the dopamine-mediated suppression of neurotensin immunoreactivity in the rat striatum. Neuroscience. vol 46. issue 2. 1992-04-08. PMID:1542410. |
the distribution of neurotensin-immunoreactive structures in the rat striatum was evaluated after blockade of dopamine neurotransmission by drugs that act presynaptically (6-hydroxydopamine, reserpine) and postsynaptically, preferentially at the d2 (eticlopride, haloperidol) and d1 [(r)-(+)-8-chloro-2,3,4,5-tetrahydro-3-methyl-5-phenyl-1h-3-benzazepi n-7-ol, sch-23390] receptor sites. |
1992-04-08 |
2023-08-11 |
rat |
| M J Millan, K Bervoets, M Mavridi. The serotonin (5-HT)1A agonist, LY 165,163, induces contralateral rotation in unilateral substantia nigra-lesioned rats via dopamine receptors. Neuroscience letters. vol 130. issue 2. 1992-04-08. PMID:1795876. |
the dopamine antagonist, haloperidol (d2 greater than d1) also reduced the action of ly 165,163. |
1992-04-08 |
2023-08-11 |
rat |
| P Devoto, G De Montis, A Tagliamont. Failure by tricyclic antidepressants to affect the increase of dopamine extracellular concentrations produced by haloperidol in the caudate and accumbens nuclei of rats. Biochemical pharmacology. vol 43. issue 3. 1992-04-02. PMID:1540209. |
failure by tricyclic antidepressants to affect the increase of dopamine extracellular concentrations produced by haloperidol in the caudate and accumbens nuclei of rats. |
1992-04-02 |
2023-08-11 |
rat |