| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J Hietala, M Koulu, M Kuoppamäki, J Lappalainen, E Syvälaht. Chronic clozapine treatment down-regulates serotonin 5-HT-1c receptors in rat brain. Progress in neuro-psychopharmacology & biological psychiatry. vol 16. issue 5. 1992-09-10. PMID:1496128. |
the effects of chronic treatment with the atypical antipsychotic, clozapine, and classical antipsychotic, haloperidol, on serotonergic 5-ht-1c and dopamine d2 receptors in rat brain were studied with radioligand binding methods. |
1992-09-10 |
2023-08-11 |
rat |
| M Smiałowska, B Legutk. Haloperidol-induced increase in neuropeptide Y immunoreactivity in the locus coeruleus of the rat brain. Neuroscience. vol 47. issue 2. 1992-09-03. PMID:1386417. |
the effect of haloperidol, a dopamine (preferably d2) receptor blocking agent on neuropeptide y immunoreactivity was studied immunohistochemically in neurons of the locus coeruleus and striatum of rat brain. |
1992-09-03 |
2023-08-11 |
rat |
| R Rivest, C A Marsde. Muscarinic antagonists attenuate neurotensin-stimulated accumbens and striatal dopamine metabolism. Neuroscience. vol 47. issue 2. 1992-09-03. PMID:1641127. |
also, the increase in dopamine metabolism in the nucleus accumbens and the striatum after centrally injected haloperidol (10 micrograms, i.c.v.) |
1992-09-03 |
2023-08-11 |
rat |
| H Lublin, J Gerlach, U Hagert, B Meidahl, C Mølbjerg, V Pedersen, C Rendtorff, E Tolvane. Zuclopenthixol, a combined dopamine D1/D2 antagonist, versus haloperidol, a dopamine D2 antagonist, in tardive dyskinesia. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 1. issue 4. 1992-09-01. PMID:1822319. |
zuclopenthixol, a combined dopamine d1/d2 antagonist, versus haloperidol, a dopamine d2 antagonist, in tardive dyskinesia. |
1992-09-01 |
2023-08-11 |
Not clear |
| J Ichikawa, H Y Meltze. The effect of chronic atypical antipsychotic drugs and haloperidol on amphetamine-induced dopamine release in vivo. Brain research. vol 574. issue 1-2. 1992-08-28. PMID:1379112. |
the effect of chronic atypical antipsychotic drugs and haloperidol on amphetamine-induced dopamine release in vivo. |
1992-08-28 |
2023-08-11 |
rat |
| Y Minabe, C R Ashby, R Y Wan. Effects produced by acute and chronic treatment with granisetron alone or in combination with haloperidol on midbrain dopamine neurons. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 2. issue 2. 1992-08-25. PMID:1321681. |
effects produced by acute and chronic treatment with granisetron alone or in combination with haloperidol on midbrain dopamine neurons. |
1992-08-25 |
2023-08-11 |
Not clear |
| Y Minabe, C R Ashby, R Y Wan. Effects produced by acute and chronic treatment with granisetron alone or in combination with haloperidol on midbrain dopamine neurons. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 2. issue 2. 1992-08-25. PMID:1321681. |
acute coadministration of granisetron with haloperidol also attenuated or abolished haloperidol's action, particularly that on the a9 dopamine cells. |
1992-08-25 |
2023-08-11 |
Not clear |
| Y Minabe, C R Ashby, R Y Wan. Effects produced by acute and chronic treatment with granisetron alone or in combination with haloperidol on midbrain dopamine neurons. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 2. issue 2. 1992-08-25. PMID:1321681. |
however, the combination of haloperidol and granisetron nullifies changes in midbrain dopamine neurons observed with either agent alone. |
1992-08-25 |
2023-08-11 |
Not clear |
| M Kaneko, K Sato, R Horikoshi, M Yaginuma, N Yaginuma, M Shiragata, H Kumashir. Effect of haloperidol on cyclic AMP and inositol trisphosphate in rat striatum in vivo. Prostaglandins, leukotrienes, and essential fatty acids. vol 46. issue 1. 1992-08-20. PMID:1378633. |
to investigate the effect of haloperidol (hal) on second messengers in the brain striatum, the concentrations of camp and inositol trisphosphate (ip-3) were measured in the striatum of rats in vivo after intravenous administration of hal, and their concentrations were compared with the severity of catalepsy and changes in dopamine (da) metabolism in the striatum. |
1992-08-20 |
2023-08-11 |
rat |
| N Ono, T Abiru, K Sugiyama, H Kamiy. Influences of cyclooxygenase inhibitors on the cataleptic behavior induced by haloperidol in mice. Prostaglandins, leukotrienes, and essential fatty acids. vol 46. issue 1. 1992-08-20. PMID:1378634. |
striatal 3,4-dihydroxyphenylacetic acid (dopac) and 5-hydroxyindole 3 acetic acid (5-hiaa) were elevated by haloperidol, although dopamine (da) and 5-hydroxytryptamine (5-ht) levels did not change. |
1992-08-20 |
2023-08-11 |
mouse |
| F Karoum, M F Ega. Dopamine release and metabolism in the rat frontal cortex, nucleus accumbens, and striatum: a comparison of acute clozapine and haloperidol. British journal of pharmacology. vol 105. issue 3. 1992-08-20. PMID:1628156. |
dopamine release and metabolism in the rat frontal cortex, nucleus accumbens, and striatum: a comparison of acute clozapine and haloperidol. |
1992-08-20 |
2023-08-11 |
rat |
| F Karoum, M F Ega. Dopamine release and metabolism in the rat frontal cortex, nucleus accumbens, and striatum: a comparison of acute clozapine and haloperidol. British journal of pharmacology. vol 105. issue 3. 1992-08-20. PMID:1628156. |
and haloperidol (hal) (0.05-1.0 mg kg-1), were compared on dopamine release and metabolism in the rat prefrontal cortex (pfc), nucleus accumbens (acc) and striatum (st). |
1992-08-20 |
2023-08-11 |
rat |
| J W Polli, R L Kincaid, J Torris, M L Billingsle. Expression of calmodulin-dependent enzymes in developing rat striatum is not affected by perturbation of dopaminergic systems. Synapse (New York, N.Y.). vol 9. issue 2. 1992-08-19. PMID:1821485. |
therefore, the possible role of nigrostriatal dopamine systems regulating the expression of cam-dependent enzymes was studied in sprague-dawley rats by using surgical hemitransections of brain, 6-hydroxydopamine lesions, and chronic haloperidol treatments. |
1992-08-19 |
2023-08-11 |
rat |
| M van den Buus. Central effects of quinpirole on blood pressure of spontaneously hypertensive rats. The Journal of pharmacology and experimental therapeutics. vol 262. issue 1. 1992-08-11. PMID:1352551. |
the pressor effect of quinpirole was enhanced by pretreatment with the peripheral d-2 antagonist domperidone, but blocked by the centrally acting dopamine antagonists haloperidol or sulpiride. |
1992-08-11 |
2023-08-11 |
rat |
| R C Pierce, G V Rebe. Dopamine-, NMDA- and sigma-receptor antagonists exert differential effects on basal and amphetamine-induced changes in neostriatal ascorbate and DOPAC in awake, behaving rats. Brain research. vol 579. issue 1. 1992-08-10. PMID:1352478. |
simultaneous measurements of extracellular dopac, a major dopamine metabolite, revealed that haloperidol, clozapine, sulpiride and bmy-14802 elevated basal levels and reversed the amphetamine-induced decline. |
1992-08-10 |
2023-08-11 |
rat |
| J Maj, Z Rogóz, G Skuz. Locomotor hyperactivity induced by MK-801 in rats. Polish journal of pharmacology and pharmacy. vol 43. issue 6. 1992-08-07. PMID:1687944. |
the mk-801-induced hyperactivity in rats was antagonized by haloperidol and, to a lesser degree, by sch 23390, a dopamine d-1 antagonist, and sulpiride, a dopamine d-2 antagonist. |
1992-08-07 |
2023-08-11 |
rat |
| M Diana, M Collu, A Mura, G L Gess. Haloperidol-induced vacuous chewing in rats: suppression by alpha-methyl-tyrosine. European journal of pharmacology. vol 211. issue 3. 1992-08-06. PMID:1352256. |
haloperidol-induced vc were inhibited by the s.c. administration of the specific dopamine d1, receptor antagonist, sch 23390 (0.025-0.100 mg/kg), in a dose-dependent manner, and were totally suppressed by an acute challenge with haloperidol (2 mg/kg i.p.) |
1992-08-06 |
2023-08-11 |
rat |
| E Toth, H Sershen, A Hashim, E S Vizi, A Lajth. Effect of nicotine on extracellular levels of neurotransmitters assessed by microdialysis in various brain regions: role of glutamic acid. Neurochemical research. vol 17. issue 3. 1992-08-05. PMID:1352387. |
the cholinergic antagonists mecamylamine and atropine, the dopaminergic antagonists haloperidol and sulpiride, and the excitatory amino acid antagonist kynurenic acid all inhibited the nicotine-induced increase of extracellular dopamine in the striatum. |
1992-08-05 |
2023-08-11 |
rat |
| T Honm. Brain microdialysis study of the effects of hazardous chemicals on the central nervous system. 1. Changes in monoamine metabolites induced by cerebral methyl bromide administration measured by two-probe microdialysis (TPMD) method. Industrial health. vol 30. issue 1. 1992-08-03. PMID:1377665. |
both intraperitoneal and intraventricular administration of haloperidol (a dopamine receptor blocker) increased 3,4-dihydroxyphenylacetic acid (dopac) and homovanillic acid (hva, dopamine metabolites) concentrations in the striatum. |
1992-08-03 |
2023-08-11 |
rat |
| A I Sacaan, F P Bymaster, D D Schoep. Metabotropic glutamate receptor activation produces extrapyramidal motor system activation that is mediated by striatal dopamine. Journal of neurochemistry. vol 59. issue 1. 1992-07-24. PMID:1319468. |
the dopamine antagonist haloperidol (0.3 mg/kg i.p.) |
1992-07-24 |
2023-08-11 |
rat |