| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R E See, M A Chapman, C E Murray, M Aravagir. Regional differences in chronic neuroleptic effects on extracellular dopamine activity. Brain research bulletin. vol 29. issue 3-4. 1992-11-16. PMID:1382815. |
the extracellular levels of dopamine (da) and da metabolites in the caudate-putamen (cpu) and the nucleus accumbens (na) of rats following administration of haloperidol (hal) decanoate and fluphenazine (flu) decanoate for 8 months were assessed using intracranial microdialysis 1 month after final injection. |
1992-11-16 |
2023-08-11 |
rat |
| T Kihara, M Ikeda, N Ibii, A Matsushit. Ceruletide, a CCK-like peptide, attenuates dopamine release from the rat striatum via a central site of action. Brain research. vol 588. issue 2. 1992-11-13. PMID:1393578. |
striatal dopamine (da) release induced by haloperidol (hpd) was significantly inhibited by subcutaneously administered clt (160 micrograms/kg) when given with a perfusate containing 15 mm k+. |
1992-11-13 |
2023-08-11 |
rat |
| G Anfossi, P Massucco, E Mularoni, F Cavalot, S Burzacca, L Mattiello, M Trovat. Studies on the effect of dopamine on the human platelet response. Clinical and experimental pharmacology & physiology. vol 19. issue 9. 1992-11-06. PMID:1382907. |
the effect of dopamine on platelet responses was prevented by low concentrations of alpha-adrenoceptor antagonists (phentolamine and yohimbine); antagonists of dopamine receptors (haloperidol and domperidone) were able to decrease the extent of the dopamine-induced secondary aggregating wave in the responders, but they failed to prevent the primary aggregation and the effects on platelet response to other aggregating agents. |
1992-11-06 |
2023-08-11 |
human |
| J S McElvain, J O Schen. Blockade of dopamine autoreceptors by haloperidol and the apparent dynamics of potassium-stimulated endogenous release of dopamine from and reuptake into striatal suspensions in the rat. Neuropharmacology. vol 31. issue 7. 1992-11-06. PMID:1407404. |
blockade of dopamine autoreceptors by haloperidol and the apparent dynamics of potassium-stimulated endogenous release of dopamine from and reuptake into striatal suspensions in the rat. |
1992-11-06 |
2023-08-11 |
rat |
| T I Lidsky, S P Banerje. Clozapine's mechanisms of action: non-dopaminergic activity rather than anatomical selectivity. Neuroscience letters. vol 139. issue 1. 1992-11-06. PMID:1407675. |
clozapine's but not haloperidol's subcortical actions were unaffected by dopamine depletion. |
1992-11-06 |
2023-08-11 |
rat |
| R E See, C E Murra. Changes in striatal dopamine release and metabolism during and after subchronic haloperidol administration in rats. Neuroscience letters. vol 142. issue 1. 1992-11-04. PMID:1383895. |
changes in striatal dopamine release and metabolism during and after subchronic haloperidol administration in rats. |
1992-11-04 |
2023-08-11 |
rat |
| R E See, C E Murra. Changes in striatal dopamine release and metabolism during and after subchronic haloperidol administration in rats. Neuroscience letters. vol 142. issue 1. 1992-11-04. PMID:1383895. |
the release and metabolism of dopamine (da) in the striatum of rats during and after subchronic haloperidol (hal) administration (3 weeks) was assessed using in vivo microdialysis. |
1992-11-04 |
2023-08-11 |
rat |
| T B Borowski, L Kokkinidi. Long-term influence of d-amphetamine on mesolimbic brain-stimulation reward: comparison to chronic haloperidol and naloxone effects. Pharmacology, biochemistry, and behavior. vol 43. issue 1. 1992-11-02. PMID:1409792. |
rate-intensity functions for brain-stimulation reward from the dopamine (da) a10 cell region of the ventral tegmental area (vta) were assessed following chronic exposure to d-amphetamine (10.0 mg/kg), haloperidol (1.0 mg/kg), and naloxone (20.0 mg/kg). |
1992-11-02 |
2023-08-11 |
Not clear |
| C A Mathis, J E Bishop, J M Gerdes, J M Whitney, K M Brennan, W J Jagus. Synthesis and evaluation of high affinity, aryl-substituted [18F]fluoropropylbenzamides for dopamine D-2 receptor studies. International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology. vol 19. issue 5. 1992-10-26. PMID:1399687. |
compound 18f-1 was displaced from the striatum of dogs by both d-amphetamine-stimulated dopamine release and haloperidol at doses of 1 and 0.5 mg/kg, respectively, while compound 18f-2 was displaced from the dog striatum only by haloperidol at these doses. |
1992-10-26 |
2023-08-11 |
rat |
| M Sekimoto, I Ushijima, Y Mizuki, M Yamad. [The threshold lowering effects of chronic treatment with haloperidol on beta-carboline derivative-induced tonic convulsion]. Yakubutsu, seishin, kodo = Japanese journal of psychopharmacology. vol 12. issue 3. 1992-10-26. PMID:1414032. |
to clarify a relationship between dopamine neuron and purine, gaba or benzodiazepine system, we have studied the changes in the threshold of tonic convulsion induced by each antagonist after chronic treatment with haloperidol in mice. |
1992-10-26 |
2023-08-11 |
mouse |
| M Sekimoto, I Ushijima, Y Mizuki, M Yamad. [The threshold lowering effects of chronic treatment with haloperidol on beta-carboline derivative-induced tonic convulsion]. Yakubutsu, seishin, kodo = Japanese journal of psychopharmacology. vol 12. issue 3. 1992-10-26. PMID:1414032. |
it may implicate in direct interactions between benzodiazepine and dopamine or gaba systems but may not between dopamine and gaba neurons in development of lowering seizure threshold following chronic haloperidol treatment. |
1992-10-26 |
2023-08-11 |
mouse |
| A A Grac. The depolarization block hypothesis of neuroleptic action: implications for the etiology and treatment of schizophrenia. Journal of neural transmission. Supplementum. vol 36. 1992-10-22. PMID:1356143. |
in this model, dopamine cells recorded in rats one month after partial dopamine lesions could be driven into depolarization block by the acute administration of moderate doses of haloperidol. |
1992-10-22 |
2023-08-11 |
rat |
| A A Grac. The depolarization block hypothesis of neuroleptic action: implications for the etiology and treatment of schizophrenia. Journal of neural transmission. Supplementum. vol 36. 1992-10-22. PMID:1356143. |
however, similar doses of haloperidol, which were effective at increasing dopamine levels in the striatum of intact rats, failed to change dopamine levels in lesioned rats. |
1992-10-22 |
2023-08-11 |
rat |
| B Levant, D E Grigoriadis, E B DeSouz. Characterization of [3H]quinpirole binding to D2-like dopamine receptors in rat brain. The Journal of pharmacology and experimental therapeutics. vol 262. issue 3. 1992-10-22. PMID:1356154. |
the pharmacological profile of [3h]quinpirole binding in striatum was: (-)-n-n-propylnorapomorphine (+/-)-2-amino-6,7-dihydroxyl-1,2,3,4-tetrahydronaphthalene greater than or equal to quinpirole greater than apomorphine greater than bromocriptine greater than dopamine greater than skf 38393 much greater than 5-hydroxytryptamine for putative dopamine agonists; spiperone greater than (+)-butaclamol greater than haloperidol greater than (-)-sulpiride greater than clozapine greater than sch 23390 much greater than cinanserin for antagonists. |
1992-10-22 |
2023-08-11 |
rat |
| C L Duvauchelle, M Levitin, L A MacConell, L K Lee, A Ettenber. Opposite effects of prefrontal cortex and nucleus accumbens infusions of flupenthixol on stimulant-induced locomotion and brain stimulation reward. Brain research. vol 576. issue 1. 1992-10-06. PMID:1515903. |
ventral tegmental area (vta) stimulation produced conditioned place preferences for stimulation-paired environments the magnitudes of which were dose-dependently reduced by systemic application of the dopamine antagonist, haloperidol (0.0, 0.15, 0.3 mg/kg). |
1992-10-06 |
2023-08-11 |
Not clear |
| S Kawagishi, K Yoshino, T E Jones, M Iwamoto, S Arai, N Aman. Dopamine receptor antagonists increase markedly the quantity of retrograde transport of HRP in the rat masseteric motoneuron. Brain research. vol 585. issue 1-2. 1992-09-29. PMID:1355002. |
horseradish peroxidase (hrp) was injected, bilaterally, into the rat masseter muscle, subsequent to an intramuscular or intraperitoneal injection of one of five dopamine antagonists (chlorpromazine and haloperidol as the d1 and d2 receptor antagonist, sch 23390 as the specific d1 receptor antagonist, sulpiride and domperidone as the specific d2 receptor antagonist). |
1992-09-29 |
2023-08-11 |
rat |
| M Laruelle, G E Jaskiw, B K Lipska, B Kolachana, M F Casanova, J E Kleinman, D R Weinberge. D1 and D2 receptor modulation in rat striatum and nucleus accumbens after subchronic and chronic haloperidol treatment. Brain research. vol 575. issue 1. 1992-09-24. PMID:1387032. |
studies of spontaneous locomotor activity (sla), a behavioral measure related to limbic dopamine transmission, and of dopamine d2 receptor density in the nucleus accumbens after chronic oral haloperidol treatment have yielded conflicting results. |
1992-09-24 |
2023-08-11 |
rat |
| M Volonté, A Ceci, F Borsin. Effect of haloperidol and clozapine on (+)SKF 10,047-induced dopamine release: role of 5-HT3 receptors. European journal of pharmacology. vol 213. issue 1. 1992-09-14. PMID:1499654. |
effect of haloperidol and clozapine on (+)skf 10,047-induced dopamine release: role of 5-ht3 receptors. |
1992-09-14 |
2023-08-11 |
rat |
| M Volonté, A Ceci, F Borsin. Effect of haloperidol and clozapine on (+)SKF 10,047-induced dopamine release: role of 5-HT3 receptors. European journal of pharmacology. vol 213. issue 1. 1992-09-14. PMID:1499654. |
haloperidol by itself increased dopamine release in both areas and these effects were additive with those induced by (+)skf 10,047. |
1992-09-14 |
2023-08-11 |
rat |
| C R Bowden, S J Voina, R Woestenborghs, R De Coster, J Heykant. Stimulation by risperidone of rat prolactin secretion in vivo and in cultured pituitary cells in vitro. The Journal of pharmacology and experimental therapeutics. vol 262. issue 2. 1992-09-11. PMID:1380082. |
compared to haloperidol, risperidone was 0.34 (95% confidence interval: 0.23, 0.48) times as potent in reversing the suppression by dopamine of rat anterior pituitary cell prolactin release in vitro, which is consistent with the compounds' striatal d2 receptor binding potencies in vitro. |
1992-09-11 |
2023-08-11 |
rat |