| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R R Gaĭnetdinov, A I Gromov, V S Kudrin, M S Pletniko. [Effects of haloperidol on extracellular contents of dopamine and its metabolites in the septum of rats during interspecies aggression]. Biulleten' eksperimental'noi biologii i meditsiny. vol 114. issue 9. 1993-02-08. PMID:1477338. |
the extracellular levels of dopamine (da) and its metabolites in the septum of freely moving rats were studied using "push-pull" method during muricidal aggression before and after haloperidol (2 mg/kg, i. p.) treatment. |
1993-02-08 |
2023-08-11 |
rat |
| A F Iakimovskiĭ, I V Karpov. [The effect of chronic activation and block of the dopamin- and enkephalinergic systems of the neostriatum on conditioned-reflex behavior abd dopamine metabolism in the nigrostriatal system of rats]. Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova. vol 42. issue 5. 1993-02-05. PMID:1336279. |
were studied the effects of bilateral daily intrastriatal microinjections in the course of two weeks of amphetamine (45 mcg), haloperidol (5 mcg), naloxone (5 mcg), and enkephalin synthetic tetrapeptide analogue (15 mcg) on behaviour and the level of dopamine and its metabolites in the striatum and substantia nigra of rats. |
1993-02-05 |
2023-08-11 |
rat |
| A F Iakimovskiĭ, I V Karpov. [The effect of chronic activation and block of the dopamin- and enkephalinergic systems of the neostriatum on conditioned-reflex behavior abd dopamine metabolism in the nigrostriatal system of rats]. Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova. vol 42. issue 5. 1993-02-05. PMID:1336279. |
both amphetamine and haloperidol lowered significantly striatal dopamine level and increased the level of its metabolites. |
1993-02-05 |
2023-08-11 |
rat |
| C J Schmidt, G M Fadayel, C K Sullivan, V L Taylo. 5-HT2 receptors exert a state-dependent regulation of dopaminergic function: studies with MDL 100,907 and the amphetamine analogue, 3,4-methylenedioxymethamphetamine. European journal of pharmacology. vol 223. issue 1. 1993-02-05. PMID:1362159. |
in contrast to its effect on mdma-induced synthesis, mdl 100,907 did not alter dopamine synthesis stimulated by haloperidol or reserpine. |
1993-02-05 |
2023-08-11 |
Not clear |
| C J Schmidt, G M Fadayel, C K Sullivan, V L Taylo. 5-HT2 receptors exert a state-dependent regulation of dopaminergic function: studies with MDL 100,907 and the amphetamine analogue, 3,4-methylenedioxymethamphetamine. European journal of pharmacology. vol 223. issue 1. 1993-02-05. PMID:1362159. |
in vivo dopamine release produced by haloperidol was also unaffected by mdl 100,907. |
1993-02-05 |
2023-08-11 |
Not clear |
| R A Glennon, R Higgs, R Young, H Iss. Further studies on N-methyl-1(3,4-methylenedioxyphenyl)-2-aminopropane as a discriminative stimulus: antagonism by 5-hydroxytryptamine3 antagonists. Pharmacology, biochemistry, and behavior. vol 43. issue 4. 1993-02-01. PMID:1361990. |
low doses of the 5-hydroxytryptamine1a (5-ht1a) antagonist nan-190, the 5-ht2 antagonist pirenperone, and the dopamine antagonist haloperidol were able to somewhat attenuate the mdma stimulus; however, none of these agents decreased mdma-appropriate responding to less than 46%. |
1993-02-01 |
2023-08-11 |
rat |
| M J Durcan, P F Morga. Opioid receptor mediation of the hypothermic response to caffeine. European journal of pharmacology. vol 224. issue 2-3. 1993-01-28. PMID:1334837. |
pretreatment with the alpha 2-adrenoceptor antagonist, atipamezole; the beta-adrenoceptor antagonist, propranolol; the dopamine antagonist, haloperidol; or the benzodiazepine receptor antagonist, flumazenil had no intrinsic effects on core body temperature nor did they interact significantly with the hypothermic effects of caffeine. |
1993-01-28 |
2023-08-11 |
mouse |
| H Tsuchihashi, T Sasaki, S Kojima, T Nagatom. Binding of [3H]haloperidol to dopamine D2 receptors in the rat striatum. The Journal of pharmacy and pharmacology. vol 44. issue 11. 1993-01-25. PMID:1361536. |
binding of [3h]haloperidol to dopamine d2 receptors in the rat striatum. |
1993-01-25 |
2023-08-11 |
rat |
| H Tsuchihashi, T Sasaki, S Kojima, T Nagatom. Binding of [3H]haloperidol to dopamine D2 receptors in the rat striatum. The Journal of pharmacy and pharmacology. vol 44. issue 11. 1993-01-25. PMID:1361536. |
the present study was designed to examine the properties of [3h]haloperidol binding to dopamine d2-receptors in rat striatum membranes, displacement potencies of various chemicals and differences between the affinities of various chemicals and two new 5-hydroxytryptamine (5-ht2) receptor antagonists, mci-9042, (+/-)-2-(dimethylamino)-1-[[o-(m-methoxyphenetyl)phenoxy]methyl]et hyl hydrogen succinate hydrochloride and one of its metabolites. |
1993-01-25 |
2023-08-11 |
rat |
| K P Murphy, S A Greenfiel. Neuronal selectivity of ATP-sensitive potassium channels in guinea-pig substantia nigra revealed by responses to anoxia. The Journal of physiology. vol 453. 1993-01-15. PMID:1464828. |
the axonic response of these neurones was not blocked by tea (5-10 mm), haloperidol (100 microm), the removal of extracellular calcium or depletion of endogenous dopamine. |
1993-01-15 |
2023-08-11 |
Not clear |
| R Schwabe, R Thiel, I Chahoud, D Neuber. Effects of a single haloperidol application to neonatal and early postnatal rats on the neurotransmitter content in the corpus striatum. Archives of toxicology. vol 66. issue 8. 1993-01-11. PMID:1281400. |
we investigated the influence of the dopamine antagonist haloperidol on the neurotransmitter content in the developing rat brain. |
1993-01-11 |
2023-08-11 |
rat |
| L H Tsai, J T Chen. The effect of exogenous dopamine on ileal smooth muscle of guinea-pigs. The Chinese journal of physiology. vol 35. issue 2. 1993-01-06. PMID:1360398. |
dopamine-induced relaxation at low concentration was reversed by haloperidol, the specific antagonist of dopamine receptors. |
1993-01-06 |
2023-08-11 |
Not clear |
| L H Tsai, J T Chen. The effect of exogenous dopamine on ileal smooth muscle of guinea-pigs. The Chinese journal of physiology. vol 35. issue 2. 1993-01-06. PMID:1360398. |
the relaxations by dopamine induced at concentration of 1 microm or higher were abolished by haloperidol with propranolol. |
1993-01-06 |
2023-08-11 |
Not clear |
| T Tsuneizumi, S M Babb, B M Cohe. Drug distribution between blood and brain as a determinant of antipsychotic drug effects. Biological psychiatry. vol 32. issue 9. 1992-12-31. PMID:1360262. |
for most neuroleptics, including drugs with high (fluphenazine, haloperidol) and low potency (thioridazine) such as dopamine d2 antagonists, concentration of drug in the brain was similar. |
1992-12-31 |
2023-08-11 |
rat |
| J L Wiley, J H Porte. Serotonergic drugs do not substitute for clozapine in clozapine-trained rats in a two-lever drug discrimination procedure. Pharmacology, biochemistry, and behavior. vol 43. issue 3. 1992-12-30. PMID:1448493. |
the present study examined the effects of haloperidol (d2 dopamine antagonist), ritanserin (5-ht2 antagonist), 1-alpha h,3-alpha,5-alpha h-tropan-3yl-3,5-dichlorobenzoate (mdl 72222) (5-ht3 antagonist), and buspirone (5-ht1a agonist) in stimulus substitution tests with rats trained to discriminate clozapine (5.0 mg/kg, ip) from vehicle in a two-lever drug discrimination procedure under a fixed ratio 30 schedule of food reinforcement. |
1992-12-30 |
2023-08-11 |
rat |
| M Sallaz, F Jourda. Apomorphine disrupts odour-induced patterns of glomerular activation in the olfactory bulb. Neuroreport. vol 3. issue 10. 1992-12-23. PMID:1421083. |
this effect is abolished by a previous injection of the dopamine antagonist haloperidol (0.1 mg kg-1). |
1992-12-23 |
2023-08-11 |
rat |
| O Elibol, C Güler, N Yükse. The effects of dopamine, haloperidol and bromocriptine on intraocular pressure. International ophthalmology. vol 16. issue 4-5. 1992-12-23. PMID:1428569. |
the effects of dopamine, haloperidol and bromocriptine on intraocular pressure. |
1992-12-23 |
2023-08-11 |
human |
| O Elibol, C Güler, N Yükse. The effects of dopamine, haloperidol and bromocriptine on intraocular pressure. International ophthalmology. vol 16. issue 4-5. 1992-12-23. PMID:1428569. |
in a double-blind randomised, prospective single dose study, we measured intraocular pressure (iop), pupil diameter, systemic blood pressure and heart rate in 43 ocular normotensive subjects before (baseline) and 2, 4, and 6 hours after topical instillation of the following drugs: dopamine 2% (n = 11), a dopamine receptor blocking drug, haloperidol 0.5% (n = 11), a dopamine receptor stimulating drug, bromocriptine 0.05% (n = 11) and 0.1% (n = 10). |
1992-12-23 |
2023-08-11 |
human |
| O Elibol, C Güler, N Yükse. The effects of dopamine, haloperidol and bromocriptine on intraocular pressure. International ophthalmology. vol 16. issue 4-5. 1992-12-23. PMID:1428569. |
in the groups receiving dopamine or haloperidol, there were no significant differences in iop compared with baseline values (p > 0.01). |
1992-12-23 |
2023-08-11 |
human |
| J R Hollerman, A A Grac. Subthalamic nucleus cell firing in the 6-OHDA-treated rat: basal activity and response to haloperidol. Brain research. vol 590. issue 1-2. 1992-12-15. PMID:1422838. |
these results suggest that the subthalamic nucleus is probably not involved in the increases in basal levels of dopamine cell activity observed previously in the 6-ohda-treated rat, but may play a role in the acute induction of depolarization block of dopamine cell firing in response to haloperidol administration in this model. |
1992-12-15 |
2023-08-11 |
rat |