| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G Cohen, M B Spin. Deprenyl suppresses the oxidant stress associated with increased dopamine turnover. Annals of neurology. vol 26. issue 5. 1989-12-20. PMID:2510589. |
when increased turnover of dopamine was provoked in mice by injection of haloperidol (1 mg/kg), the concentration of gssg in the striatum tripled. |
1989-12-20 |
2023-08-11 |
mouse |
| G A Gudelsky, H Y Meltze. Activation of tuberoinfundibular dopamine neurons following the acute administration of atypical antipsychotics. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 2. issue 1. 1989-12-12. PMID:2572233. |
in contrast, the activity of these hypothalamic dopamine neurons was not acutely altered by the typical antipsychotics haloperidol, chlorpromazine, fluphenazine, and cis-flupentixol or by sch 23390. |
1989-12-12 |
2023-08-11 |
Not clear |
| D Duterte-Boucher, B Naudin, J Costenti. Characteristics of the dopamine receptors involved in the anorectic effects of apomorphine in mice. Fundamental & clinical pharmacology. vol 3. issue 4. 1989-12-05. PMID:2553567. |
mice submitted to a semi-chronic (6 d) blockade of dopamine receptors by haloperidol or injected intracerebroventricularly with 125 micrograms 6-hydroxydopamine 21 d before testing failed to develop a hypersensitivity to the anorectic effect of apomorphine (60 micrograms/kg). |
1989-12-05 |
2023-08-11 |
mouse |
| K A Keefe, J D Salamone, M J Zigmond, E M Stricke. Paradoxical kinesia in parkinsonism is not caused by dopamine release. Studies in an animal model. Archives of neurology. vol 46. issue 10. 1989-11-09. PMID:2508609. |
these behaviors were not abolished by pretreating the animals with the dopamine antagonists haloperidol and sch-23390. |
1989-11-09 |
2023-08-11 |
rat |
| P W Kalivas, P Duffy, J Barro. Regulation of the mesocorticolimbic dopamine system by glutamic acid receptor subtypes. The Journal of pharmacology and experimental therapeutics. vol 251. issue 1. 1989-11-07. PMID:2552079. |
glutamate produced an increase in motor behavior that was antagonized by pretreatment with the dopamine d2 receptor antagonist, haloperidol. |
1989-11-07 |
2023-08-11 |
rat |
| K E Asin, W E Montan. Studies on D1 and D2 dopamine receptor involvement in conditioned taste aversions. Pharmacology, biochemistry, and behavior. vol 32. issue 4. 1989-11-07. PMID:2572001. |
this aversion was blocked by injections of haloperidol and was attenuated following injections of domperidone, suggesting involvement of peripheral dopamine receptors in the aversion. |
1989-11-07 |
2023-08-11 |
rat |
| E S Prosser, R Pruthi, J G Csernansk. Differences in the time course of dopaminergic supersensitivity following chronic administration of haloperidol, molindone, or sulpiride. Psychopharmacology. vol 99. issue 1. 1989-10-25. PMID:2506596. |
the onset and persistence of changes in 3h-spiroperidol binding to dopamine (da) d2 receptors were examined in rat mesolimbic and striatal brain regions following daily administration of haloperidol, molindone, or sulpiride for 3, 7, 14, or 28 days. |
1989-10-25 |
2023-08-11 |
rat |
| T Lundberg, L H Lindström, P Hartvig, S A Eckernâs, B Ekblom, H Lundqvist, K J Fasth, P Gullberg, B Långströ. Striatal and frontal cortex binding of 11-C-labelled clozapine visualized by positron emission tomography (PET) in drug-free schizophrenics and healthy volunteers. Psychopharmacology. vol 99. issue 1. 1989-10-25. PMID:2528781. |
after haloperidol pretreatment, the binding of 11c-clozapine in striatum and frontal cortex was reduced, more pronounced in the striatum, indicating competition for d-2 dopamine binding sites. |
1989-10-25 |
2023-08-11 |
human |
| H Higashi, K Inanaga, S Nishi, N Uchimur. Enhancement of dopamine actions on rat nucleus accumbens neurones in vitro after methamphetamine pre-treatment. The Journal of physiology. vol 408. 1989-10-25. PMID:2550628. |
haloperidol (1 microm) reversibly suppressed both responses to dopamine; (-)-sulpiride (1 microm) selectively abolished the depolarization and prolonged the hyperpolarization. |
1989-10-25 |
2023-08-11 |
rat |
| H Higashi, K Inanaga, S Nishi, N Uchimur. Enhancement of dopamine actions on rat nucleus accumbens neurones in vitro after methamphetamine pre-treatment. The Journal of physiology. vol 408. 1989-10-25. PMID:2550628. |
haloperidol (1 microm) completely reversed the depressions of the epsps and ca2+-dependent spikes by dopamine, while (-)-sulpiride (1 microm) was only partially effective. |
1989-10-25 |
2023-08-11 |
rat |
| K M Dhasmana, A K Banerjee, Y N Zhu, W Erdmann, S S Parmar, S K Salzma. Role of dopamine receptors in gastrointestinal motility. Research communications in chemical pathology and pharmacology. vol 64. issue 3. 1989-10-13. PMID:2571179. |
the decrease in apomorphine (50 micrograms) and dopamine (100 and 200 micrograms)-induced gastrointestinal transit after intracisternal administration was antagonized by haloperidol. |
1989-10-13 |
2023-08-11 |
rat |
| A Ray, P G Henk. Role of dopaminergic mechanisms in the central amygdalar nucleus in the regulation of stress-induced gastric ulcer formation in rats. The Indian journal of medical research. vol 90. 1989-09-27. PMID:2767748. |
microinjections (i/am) of dopamine (da) antagonists, haloperidol or clozapine (1 and 5 micrograms) into the central amygdalar nucleus (cea) produced dose-related aggravations in cold-restraint (3 h at 4 degrees c) stress-induced gastric ulcer formation in rats. |
1989-09-27 |
2023-08-11 |
rat |
| M Yamamura, H Nakagawa, K Maeda, K Kinoshita, R Ishid. Effects of mafoprazine, a phenylpiperazine derivative, on the central dopaminergic system. Japanese journal of pharmacology. vol 50. issue 3. 1989-09-20. PMID:2569544. |
these results suggest that mafoprazine has a relatively selective postsynaptic dopamine d2-receptor blocking action in the nucleus accumbens compared with chlorpromazine and haloperidol and suggest that mafoprazine also has alpha 2-adrenoceptor-stimulating actions. |
1989-09-20 |
2023-08-11 |
mouse |
| P O'Connor, R B Kropf, J E Dowlin. Catecholamine-sensitive adenylate cyclase in the white perch (Roccus americanus) retina: evidence for beta-adrenergic and dopamine receptors linked to adenylate cyclase. Journal of neurochemistry. vol 53. issue 3. 1989-09-18. PMID:2547910. |
haloperidol, a dopamine antagonist, blocks the stimulatory effect of dopamine but not of isoproterenol. |
1989-09-18 |
2023-08-11 |
Not clear |
| A P Burlina, L Galzign. [Preparation, properties and therapeutic potential of cytidine diphosphocholine incorporated into liposomes]. Rivista di neurologia. vol 59. issue 1. 1989-09-12. PMID:2762734. |
the cdc-liposome association significantly increased, unlike cdc alone, the levels of dopamine catabolites in the striatum of rats treated with haloperidol (0.15 mg/kg/die) after 5 days of intravenous administration (20 mg/kg/die). |
1989-09-12 |
2023-08-11 |
rat |
| J M Farah, G P Muelle. A D-2 dopaminergic agonist stimulates secretion of anterior pituitary immunoreactive beta-endorphin in rats. Neuroendocrinology. vol 50. issue 1. 1989-09-07. PMID:2569171. |
stimulation of i beta-end release by ly141865 was also inhibited by the general dopamine antagonist, haloperidol, (0.1-3.0 mg/kg i.p., 2 h) and by the d-2 selective antagonist, sulpiride (100 micrograms/rat i.c.v., 4 h). |
1989-09-07 |
2023-08-11 |
rat |
| S R McGurk, E D Levin, L L Butche. Nicotinic-dopaminergic relationships and radial-arm maze performance in rats. Behavioral and neural biology. vol 52. issue 1. 1989-08-28. PMID:2757586. |
we have previously demonstrated that the performance deficit caused by muscarinic blockade is enhanced by coadministration of the nicotinic antagonist, mecamylamine, and is diminished by coadministration of the dopamine antagonist, haloperidol. |
1989-08-28 |
2023-08-11 |
rat |
| J K Chivers, C Reavill, P Jenner, C D Marsde. Definition of the in-vivo binding of [3H]spiperone in rat brain using substituted benzamide drugs. The Journal of pharmacy and pharmacology. vol 41. issue 2. 1989-08-25. PMID:2568417. |
the ability of some substituted benzamide drugs to define in-vivo the binding of [3h]spiperone to brain dopamine receptors in rats was assessed using behaviourally effective doses in comparison with haloperidol. |
1989-08-25 |
2023-08-11 |
rat |
| J K Chivers, C Reavill, P Jenner, C D Marsde. Definition of the in-vivo binding of [3H]spiperone in rat brain using substituted benzamide drugs. The Journal of pharmacy and pharmacology. vol 41. issue 2. 1989-08-25. PMID:2568417. |
as judged using haloperidol, [3h]spiperone identified dopamine receptors in the substantia nigra, striatum, tuberculum olfactorium and hypothalamus, but not in frontal cortex or nucleus accumbens. |
1989-08-25 |
2023-08-11 |
rat |
| P A Copeland, P Thoma. Control of gonadotropin release in the Atlantic croaker (Micropogonias undulatus): evidence for lack of dopaminergic inhibition. General and comparative endocrinology. vol 74. issue 3. 1989-08-25. PMID:2663630. |
none of the dopamine antagonists tested, metoclopramide, pimozide, haloperidol, and domperidone, were able to increase plasma gth levels above those induced by treatment with lhrha alone and in some cases the gonadotropin response to lhrha was reduced. |
1989-08-25 |
2023-08-11 |
Not clear |