| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| W Zhang, H Tilson, M K Stachowiak, J S Hon. Repeated haloperidol administration changes basal release of striatal dopamine and subsequent response to haloperidol challenge. Brain research. vol 484. issue 1-2. 1989-06-15. PMID:2713698. |
the effects of acute or repeated administration of haloperidol on release of dopamine (da) and homovanillic acid (hva) from striata of awake rats were studied using a microdialysis probe. |
1989-06-15 |
2023-08-11 |
rat |
| T Rammsaye. Dopaminergic and serotoninergic influence on duration discrimination and vigilance. Pharmacopsychiatry. vol 22 Suppl 1. 1989-06-15. PMID:2717665. |
there is some evidence from animal studies suggesting that dopamine (da) agonists speed up a hypothesised internal clock, whereas da antagonists such as haloperidol slow down the clock rate. |
1989-06-15 |
2023-08-11 |
human |
| R Meloni, J Childs, F Gerogan, S Yurkofsky, K Gal. Effect of haloperidol on transplants of fetal substantia nigra: evidence for feedback regulation of dopamine turnover in the graft and its projections. Progress in brain research. vol 78. 1989-06-15. PMID:2854639. |
effect of haloperidol on transplants of fetal substantia nigra: evidence for feedback regulation of dopamine turnover in the graft and its projections. |
1989-06-15 |
2023-08-11 |
Not clear |
| L Galzigna, C Fasolato, M Bianchi, A P Burlina, A Previer. Dopamine-depleting activity of L-3,4-(dioxyphenylacetyl)-phenylalanine. Neuropsychobiology. vol 19. issue 4. 1989-06-09. PMID:3247016. |
this new dopa derivative is slightly inhibitory towards monoamine oxidase (ic50 2.5 mm) and the synaptosomal uptake of dopamine (ic50 0.35 mm) and acts as an antagonist of haloperidol (ic50 0.6 microm) in displacing 3h-spiroperidol from isolated dopamine receptors. |
1989-06-09 |
2023-08-11 |
mouse |
| L H Burns, A E Kelle. Neurokinin-alpha injected into the ventral tegmental area elicits a dopamine-dependent behavioral activation in the rat. Pharmacology, biochemistry, and behavior. vol 31. issue 2. 1989-06-06. PMID:2469085. |
in a second experiment, the behavioral activation by nka (2.0 micrograms) was blocked by pretreatment with haloperidol (0.2 mg/kg), confirming that the nka-induced effect is mediated by dopamine. |
1989-06-06 |
2023-08-11 |
rat |
| T Ljungber. Dopamine D-2 antagonists reverse apomorphine-induced decreased water intake in the rat: prediction of antipsychotic drugs with few extrapyramidal side-effects? Journal of neural transmission. vol 76. issue 2. 1989-06-06. PMID:2565360. |
four different dopamine (da) d-2 antagonists were used to counteract this effect of apomorphine; haloperidol [an antipsychotic inducing extrapyramidal side-effects (eps)], sulpiride (an antipsychotic inducing less eps than haloperidol), metoclopramide (not used as an antipsychotic but inducing eps) and domperidone (not passing through the blood brain barrier). |
1989-06-06 |
2023-08-11 |
rat |
| R M Sullivan, P G Henke, A Ra. The effects of buspirone, a selective anxiolytic, on stress ulcer formation in rats. Pharmacology, biochemistry, and behavior. vol 31. issue 2. 1989-06-06. PMID:3244709. |
the dopamine antagonist haloperidol, and the agonist apomorphine respectively, reversed the buspirone effects. |
1989-06-06 |
2023-08-11 |
rat |
| M J During, I N Acworth, R J Wurtma. Dopamine release in rat striatum: physiological coupling to tyrosine supply. Journal of neurochemistry. vol 52. issue 5. 1989-06-02. PMID:2496199. |
pretreatment with haloperidol or the partial lesioning of nigrostriatal neurons enhanced the effect of tyrosine on dopamine release, and haloperidol also prolonged this effect. |
1989-06-02 |
2023-08-11 |
rat |
| D B Pritchett, A W Bach, M Wozny, O Taleb, R Dal Toso, J C Shih, P H Seebur. Structure and functional expression of cloned rat serotonin 5HT-2 receptor. The EMBO journal. vol 7. issue 13. 1989-06-02. PMID:2854054. |
membranes from transfected cells showed high-affinity binding of the serotonin antagonists spiperone, ketanserin and mianserin, low affinity for haloperidol (a dopamine d2 receptor antagonist), 8-oh-dpat as well as mdl-72222 and no detectable binding of [3h]serotonin. |
1989-06-02 |
2023-08-11 |
rat |
| N E Andén, J Grenhoff, T H Svensso. Does treatment with haloperidol for 3 weeks produce depolarization block in midbrain dopamine neurons of unanaesthetized rats? Psychopharmacology. vol 96. issue 4. 1989-06-02. PMID:3149782. |
does treatment with haloperidol for 3 weeks produce depolarization block in midbrain dopamine neurons of unanaesthetized rats? |
1989-06-02 |
2023-08-11 |
rat |
| N E Andén, J Grenhoff, T H Svensso. Does treatment with haloperidol for 3 weeks produce depolarization block in midbrain dopamine neurons of unanaesthetized rats? Psychopharmacology. vol 96. issue 4. 1989-06-02. PMID:3149782. |
treatment of rats with haloperidol, 0.5 mg/kg sc daily for 3 weeks, did not increase the concentration of dopamine in the dopamine-rich nuclei of the forebrain apart from a small effect in the olfactory tubercle. |
1989-06-02 |
2023-08-11 |
rat |
| R Kapoor, C Webb, S A Greenfiel. Endogenous dopamine modifies electroresponsiveness of pars compacta cells in the guinea pig substantia nigra in vitro. Experimental brain research. vol 74. issue 3. 1989-06-01. PMID:2707341. |
similar changes were observed in control slices on exposure to the dopamine antagonist haloperidol. |
1989-06-01 |
2023-08-11 |
Not clear |
| S Welsch-Kunze, K Nowak, K Kuschinsk. Conditioned behavioural responses to apomorphine: extinction and haloperidol-induced inhibition. Naunyn-Schmiedeberg's archives of pharmacology. vol 338. issue 6. 1989-05-31. PMID:3244399. |
in the present experiments, the extinction of these conditioned stereotypies was studied in one series; in another series, the possible inhibition of conditioned stereotypies by the blocker of dopamine receptors, haloperidol, was measured. |
1989-05-31 |
2023-08-11 |
rat |
| A D Sherma. Isolation of metabolically distinct synaptosomes on Percoll gradients. Neurochemical research. vol 14. issue 1. 1989-05-26. PMID:2565542. |
these results suggest that haloperidol interferes with glutamate release and synthesis via a mechanism which may not involve adenosine, serotonin, or dopamine. |
1989-05-26 |
2023-08-11 |
rat |
| H S Aabec. [Tourette syndrome. New aspects on pharmacological treatment]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke. vol 109. issue 9. 1989-05-12. PMID:2565050. |
the two most utilized agents, haloperidol and pimozide, decrease central dopaminergic activity by blocking dopamine receptors and have been shown to improve the symptomatology of tourette syndrome. |
1989-05-12 |
2023-08-11 |
Not clear |
| J R Hollerman, A A Grac. Acute haloperidol administration induces depolarization block of nigral dopamine neurons in rats after partial dopamine lesions. Neuroscience letters. vol 96. issue 1. 1989-05-11. PMID:2494609. |
acute haloperidol administration induces depolarization block of nigral dopamine neurons in rats after partial dopamine lesions. |
1989-05-11 |
2023-08-11 |
rat |
| J R Hollerman, A A Grac. Acute haloperidol administration induces depolarization block of nigral dopamine neurons in rats after partial dopamine lesions. Neuroscience letters. vol 96. issue 1. 1989-05-11. PMID:2494609. |
the effects of the antipsychotic drug haloperidol (hal) on the electrophysiological activity of dopamine (da)-containing cells in the substantia nigra was assessed in rats 6 weeks after partial 6-hydroxydopamine (6-ohda)-induced lesions of the nigrostriatal da pathway. |
1989-05-11 |
2023-08-11 |
rat |
| S A Kolenik, F J Hoffman, M B Bower. Sensitivity of regional brain dopamine systems to haloperidol. Biological psychiatry. vol 25. issue 6. 1989-05-05. PMID:2923943. |
sensitivity of regional brain dopamine systems to haloperidol. |
1989-05-05 |
2023-08-11 |
Not clear |
| M Diana, S J Young, P M Grove. Modulation of dopaminergic terminal excitability by D1 selective agents. Neuropharmacology. vol 28. issue 1. 1989-04-28. PMID:2522599. |
previous studies from this laboratory have demonstrated that the electrical excitability of nigro-striatal dopaminergic terminals is reduced by the dopaminomimetics apomorphine and amphetamine and is increased by the dopamine antagonists haloperidol, fluphenazine and sulpiride (groves, fenster, tepper, nakamura, and young 1981; tepper, nakamura, young and groves 1984). |
1989-04-28 |
2023-08-11 |
Not clear |
| b' S Vyb\\xc3\\xadral, L Jansk\\xc3\\xb. The role of dopaminergic pathways in thermoregulation in the rabbit. Neuropharmacology. vol 28. issue 1. 1989-04-28. PMID:2927577.' |
intraperitoneal injections of a dopamine antagonist, haloperidol, induced a marked hypothermia, due to a downward shift of the threshold central temperature for induction of cold thermogenesis, panting and vasodilation. |
1989-04-28 |
2023-08-11 |
rabbit |