| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| H Lublin, J Gerlac. Behavioural effects of dopamine D-1 and D-2 receptor agonists in monkeys previously treated with haloperidol. European journal of pharmacology. vol 153. issue 2-3. 1988-12-21. PMID:3263277. |
behavioural effects of dopamine d-1 and d-2 receptor agonists in monkeys previously treated with haloperidol. |
1988-12-21 |
2023-08-11 |
monkey |
| V Hillegaart, S Ahlenius, C J Fowler, O Magnusso. Increased duration of dopamine receptor antagonist-induced effects on both behaviour and striatal dopamine turnover by repeated testing in rats. Pharmacology & toxicology. vol 63. issue 2. 1988-11-30. PMID:3186617. |
the present results show that the effects on striatal dopamine (da) turnover of a single dose of the da receptor antagonists haloperidol or raclopride in the rat, are dependent on the activity level of the animal during treatment. |
1988-11-30 |
2023-08-11 |
rat |
| H Maeda, S Maki, H Uchimur. Facilitatory effects of caerulein on hypothalamic defensive attack in cats. Brain research. vol 459. issue 2. 1988-11-28. PMID:3179708. |
(3) observed facilitatory effects of caerulein on the hypothalamic defensive attack were very similar to those observed with dopamine (da) agonists such as methamphetamine and apomorphine and opposite to those with da antagonists such as haloperidol and chlorpromazine. |
1988-11-28 |
2023-08-11 |
human |
| M Fantino, H Boucher, F Faïon, P Mathio. Dexfenfluramine and body weight regulation: experimental study with hoarding behavior. Clinical neuropharmacology. vol 11 Suppl 1. 1988-11-28. PMID:3180113. |
the action of dexfenfluramine is mediated through serotoninergic receptors because it is suppressed by a pretreatment with metergoline, a selective serotonin-receptor blocker, but is not modified by haloperidol, a dopamine antagonist. |
1988-11-28 |
2023-08-11 |
Not clear |
| C J Cruz, R M Beckstea. Quantitative radioimmunocytochemical evidence that haloperidol and SCH 23390 induce opposite changes in substance P levels of rat substantia nigra. Brain research. vol 457. issue 1. 1988-11-23. PMID:2458801. |
chronic blockade of the dopamine (da) d2 receptor by repeated systemic administration of the butyrophenone neuroleptic, haloperidol (hal), is known to lead to a decrease in levels of the neuroactive peptide, substance p (sp), in the rat striatum and substantia nigra (sn). |
1988-11-23 |
2023-08-11 |
rat |
| C Y Yim, G J Mogenso. Neuromodulatory action of dopamine in the nucleus accumbens: an in vivo intracellular study. Neuroscience. vol 26. issue 2. 1988-11-23. PMID:3173682. |
the effect of ventral tegmental area stimulation on the evoked depolarizing postsynaptic potential and the membrane potential were blocked by haloperidol indicating the involvement of dopamine. |
1988-11-23 |
2023-08-11 |
Not clear |
| J D Sheppard, D J Schai. Oral haloperidol lowers human intraocular pressure. Journal of ocular pharmacology. vol 2. issue 3. 1988-11-22. PMID:3503108. |
dopamine antagonists like haloperidol may act by blocking post-synaptic dopamine receptors in the ciliary body, resulting in vasoconstriction and subsequently decreased aqueous humor production. |
1988-11-22 |
2023-08-11 |
human |
| A M Judd, I S Login, K Kovacs, P C Ross, B L Spangelo, W D Jarvis, R M MacLeo. Characterization of the MMQ cell, a prolactin-secreting clonal cell line that is responsive to dopamine. Endocrinology. vol 123. issue 5. 1988-11-21. PMID:2844508. |
this inhibition is, in turn, reversed by the dopamine antagonist haloperidol and by pertussis toxin, an inactivator of the gtp-binding coupling protein. |
1988-11-21 |
2023-08-11 |
rat |
| P K Sonsalla, L Manzino, R E Heikkil. Interactions of D1 and D2 dopamine receptors on the ipsilateral vs. contralateral side in rats with unilateral lesions of the dopaminergic nigrostriatal pathway. The Journal of pharmacology and experimental therapeutics. vol 247. issue 1. 1988-11-18. PMID:2971797. |
in rats with a unilateral lesion of the nigrostriatal dopaminergic pathway, the ipsilateral rotation produced by the enhanced actions of endogenous dopamine (da) on the nonlesioned side, induced by either the da-releasing drug amphetamine or the da uptake inhibitor gbr 13069, was blocked effectively by pretreatment with either the selective d1 da receptor antagonist, sch 23390, or the d2 selective antagonist, haloperidol. |
1988-11-18 |
2023-08-11 |
rat |
| D A Haas, S R Georg. Effect of dopaminergic and alpha-adrenergic modulation on corticotropin-releasing factor immunoreactivity in rat hypothalamus. Canadian journal of physiology and pharmacology. vol 66. issue 6. 1988-11-16. PMID:2901903. |
the dopamine antagonist, haloperidol, was administered for similar periods and resulted in no overall significant effect, except for a transient decrease. |
1988-11-16 |
2023-08-11 |
rat |
| D J Cannon, D E McMillan, J E Newton, E P Fody, W S Metzer, M Claybrook, L Couch, S R Paig. Serum haloperidol and neuroleptic receptor levels in chronic psychosis. Annals of clinical and laboratory science. vol 18. issue 5. 1988-11-01. PMID:3178137. |
serum haloperidol and serum dopamine blocking activity were measured, and steady state levels were compared in 22 chronic male schizophrenic patients. |
1988-11-01 |
2023-08-11 |
Not clear |
| D J Cannon, D E McMillan, J E Newton, E P Fody, W S Metzer, M Claybrook, L Couch, S R Paig. Serum haloperidol and neuroleptic receptor levels in chronic psychosis. Annals of clinical and laboratory science. vol 18. issue 5. 1988-11-01. PMID:3178137. |
haloperidol levels were measured by high pressure liquid chromatography (hplc), and dopamine blocking activity was measured by a radioreceptor assay (nrra). |
1988-11-01 |
2023-08-11 |
Not clear |
| D J Cannon, D E McMillan, J E Newton, E P Fody, W S Metzer, M Claybrook, L Couch, S R Paig. Serum haloperidol and neuroleptic receptor levels in chronic psychosis. Annals of clinical and laboratory science. vol 18. issue 5. 1988-11-01. PMID:3178137. |
there were significant correlations at both time points among haloperidol dosage, serum haloperidol levels, and dopamine blocking activity. |
1988-11-01 |
2023-08-11 |
Not clear |
| J C Miller, A J Friedhof. Development of specificity and stereoselectivity of rat brain dopamine receptors. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 4. issue 1. 1988-10-27. PMID:2458672. |
prenatal exposure to the neuroleptic haloperidol has been reported to produce an enduring decrement in the number of dopamine d2 receptors in rat striatum and a persistent diminution of a dopamine dependent behavior, stereotypy. |
1988-10-27 |
2023-08-11 |
rat |
| J C Miller, A J Friedhof. Development of specificity and stereoselectivity of rat brain dopamine receptors. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 4. issue 1. 1988-10-27. PMID:2458672. |
it is of interest that the critical period for the prenatal effect of haloperidol to reduce striatal d2 binding sites, gd's 15-18, coincides with the period during which dopamine binding sites lack true specificity, but can be labeled with dopaminergic ligands. |
1988-10-27 |
2023-08-11 |
rat |
| O B Kuz'min, A N Kosare. [Effect of dopamine on the blood flow in various zones of the kidney cortex and medullary layer in rats]. Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova. vol 74. issue 5. 1988-10-21. PMID:2901373. |
phentolamine and propranolol did not alter the kidney response to dopamine whereas haloperidol completely prevented the dopamine vascular and channel effects. |
1988-10-21 |
2023-08-11 |
rat |
| A Gulati, R C Srimal, B N Dhawa. Differential alteration in striatal dopaminergic and cortical serotonergic receptors induced by repeated administration of haloperidol or centbutindole in rats. Pharmacology. vol 36. issue 6. 1988-10-21. PMID:2901759. |
the interactions of centbutindole with striatal dopamine and cortical 5-ht2 receptors have been studied along with haloperidol following 3 weeks of administration. |
1988-10-21 |
2023-08-11 |
rat |
| E L Al'perina, Z Zidek, G V Idova, L V Devoĭn. [Participation of the dopaminergic system in the immune response-stimulating effect of muramyl dipeptide]. Biulleten' eksperimental'noi biologii i meditsiny. vol 106. issue 8. 1988-10-21. PMID:3416056. |
stimulation of the immune response is prevented by preliminary blockade of dopamine receptors with haloperidol, that testifies to the activation of the dopaminergic system by certain mdp dosages. |
1988-10-21 |
2023-08-11 |
Not clear |
| P H Hutson, C T Dourish, G Curzo. Evidence that the hyperphagic response to 8-OH-DPAT is mediated by 5-HT1A receptors. European journal of pharmacology. vol 150. issue 3. 1988-10-18. PMID:2970974. |
although spiperone also blocks dopamine and alpha 2-adrenoreceptors, involvement of these sites is unlikely as neither the da antagonist haloperidol nor the alpha 2-adrenoceptor antagonist idazoxan blocked 8-oh-dpat-induced feeding. |
1988-10-18 |
2023-08-11 |
rat |
| F Amenta, M De Rossi, C Fruschelli, R Gerl. Identification of beta-adrenergic sensitive adenylate cyclase in rat thoracic duct. Journal of the autonomic nervous system. vol 22. issue 3. 1988-10-17. PMID:2843587. |
in contrast, the l-isoproterenol-elicited increase of camp was unaffected by the alpha-adrenergic and dopamine receptor-blocking agents phentolamine and haloperidol. |
1988-10-17 |
2023-08-11 |
rat |