| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L H Jiang, M Tsai, R Y Wan. Chronic treatment with high doses of haloperidol fails to decrease the time course for the development of depolarization inactivation of midbrain dopamine neurons. Life sciences. vol 43. issue 1. 1988-08-01. PMID:3386416. |
using extracellular single unit recording techniques, we investigated the effects produced by chronic treatment with high doses of haloperidol (chal, 5 mg/kg/day, s.c.) on midbrain dopamine (da) neuronal activity. |
1988-08-01 |
2023-08-11 |
rat |
| T Klockgether, M Schwarz, L Turski, K H Sonta. Catalepsy after microinjection of haloperidol into the rat medial prefrontal cortex. Experimental brain research. vol 70. issue 2. 1988-07-29. PMID:3384045. |
to investigate the behavioural role of mesocortical dopamine innervation we performed bilateral microinjections of haloperidol into various parts of the rat frontal cortex and into adjacent subcortical forebrain structures. |
1988-07-29 |
2023-08-11 |
rat |
| T Klockgether, M Schwarz, L Turski, K H Sonta. Catalepsy after microinjection of haloperidol into the rat medial prefrontal cortex. Experimental brain research. vol 70. issue 2. 1988-07-29. PMID:3384045. |
it is concluded that blockade of dopamine receptors located in the rostral neostriatum and in the medial prefrontal cortex contributes to the development of haloperidol induced catalepsy. |
1988-07-29 |
2023-08-11 |
rat |
| b' I I Miroshnichenko, V S Kudrin, K S Raevski\\xc4\\xa. [Effect of carbidine, sulpiride and haloperidol on levels of monoamines and their metabolites in the brain structures of rats]. Farmakologiia i toksikologiia. vol 51. issue 2. 1988-07-26. PMID:2897932.' |
haloperidol (1 mg/kg) was shown to increase significantly the dopamine (da) turnover in n. accumbens and striatum and to a lesser degree in frontal cortex and hypothalamus of the rat brain; to decrease the noradrenaline content in hypothalamus. |
1988-07-26 |
2023-08-11 |
rat |
| O b Kuz'min, A N Kosare. [Effect of dopamine and its combination with furosemide on sodium transport in the rat kidney]. Farmakologiia i toksikologiia. vol 51. issue 2. 1988-07-26. PMID:3378614. |
in experiments on rats phentolamine, propranolol, indomethacin were shown to exert no significant effect on the natriuretic action of dopamine, whereas haloperidol completely prevented it. |
1988-07-26 |
2023-08-11 |
rat |
| K L Lankford, F G DeMello, W L Klei. D1-type dopamine receptors inhibit growth cone motility in cultured retina neurons: evidence that neurotransmitters act as morphogenic growth regulators in the developing central nervous system. Proceedings of the National Academy of Sciences of the United States of America. vol 85. issue 12. 1988-07-25. PMID:3380807. |
effects of dopamine on growth cone function could be reversed by haloperidol or (+)-sch 23390, whereas forskolin elicited a response similar to dopamine; these data show the response was receptor-mediated, acting through a d1-type system, and are consistent with the use of camp as a second messenger. |
1988-07-25 |
2023-08-11 |
chicken |
| R Weiler, K Kohler, M Kirsch, H J Wagne. Glutamate and dopamine modulate synaptic plasticity in horizontal cell dendrites of fish retina. Neuroscience letters. vol 87. issue 3. 1988-07-22. PMID:2898116. |
dopamine, on the other hand, induces the formation of spinules in a dark-adapted retina and haloperidol reduces the expression in a light-adapted retina. |
1988-07-22 |
2023-08-11 |
Not clear |
| A Berkenbosch, C N Olievier, J DeGoed. Effects of the dopamine antagonists haloperidol and domperidone on the normoxic ventilatory response to CO2 in cats. Pflugers Archiv : European journal of physiology. vol 411. issue 3. 1988-07-21. PMID:3132697. |
effects of the dopamine antagonists haloperidol and domperidone on the normoxic ventilatory response to co2 in cats. |
1988-07-21 |
2023-08-11 |
Not clear |
| A Berkenbosch, C N Olievier, J DeGoed. Effects of the dopamine antagonists haloperidol and domperidone on the normoxic ventilatory response to CO2 in cats. Pflugers Archiv : European journal of physiology. vol 411. issue 3. 1988-07-21. PMID:3132697. |
we investigated the effects of the dopamine antagonists haloperidol and domperidone on the ventilatory response following square-wave changes in end-tidal co2 during normoxia in chloralose-urethane anaesthetized cats. |
1988-07-21 |
2023-08-11 |
Not clear |
| P M Carvey, A Hitri, C G Goetz, C M Tanner, H L Klawan. Concurrent treatment with benztropine and haloperidol attenuates development of behavioral hypersensitivity but not dopamine receptor proliferation. Life sciences. vol 42. issue 22. 1988-07-05. PMID:3374255. |
benztropine cotreatment attenuated the development of behavioral hypersensitivity to haloperidol but did not alter either the dopamine receptor proliferation or the striatal dopamine biochemical changes induced by haloperidol. |
1988-07-05 |
2023-08-11 |
rat |
| T Taniguchi, H Nishikawa, K Yokotani, M Fujiwar. The bindings of 3H-prazosin and 3H-yohimbine to alpha adrenoceptors in the guinea-pig stomach. Life sciences. vol 42. issue 23. 1988-07-01. PMID:2836683. |
dopaminergic drugs such as dopamine, haloperidol, domperidone and sulpiride competed for 3h-prazosin binding in order of haloperidol greater than domperidone greater than dopamine greater than sulpiride. |
1988-07-01 |
2023-08-11 |
Not clear |
| J E Freedman, F F Weigh. Single K+ channels activated by D2 dopamine receptors in acutely dissociated neurons from rat corpus striatum. Proceedings of the National Academy of Sciences of the United States of America. vol 85. issue 10. 1988-06-22. PMID:2453064. |
channel openings were rarely or never observed in the absence of drugs or in the presence of quinpirole plus the dopamine antagonist haloperidol. |
1988-06-22 |
2023-08-11 |
rat |
| P Kontro, S S Oj. Release of taurine, GABA and dopamine from rat striatal slices: mutual interactions and developmental aspects. Neuroscience. vol 24. issue 1. 1988-06-20. PMID:3368056. |
this dopamine effect was partially antagonized by haloperidol, suggesting that dopaminergic systems were able to modify taurine release, possibly via dopaminergic receptors. |
1988-06-20 |
2023-08-11 |
rat |
| J M Walker, R R Matsumoto, W D Bowen, D L Gans, K D Jones, F O Walke. Evidence for a role of haloperidol-sensitive sigma-'opiate' receptors in the motor effects of antipsychotic drugs. Neurology. vol 38. issue 6. 1988-06-17. PMID:2897093. |
since haloperidol (and many other antipsychotic drugs) exhibit an affinity for sigma-receptors which is at least equal to its affinity for dopamine receptors, these data raise the further possibility that sigma-receptors are involved in the motor side effects of antipsychotic drugs. |
1988-06-17 |
2023-08-11 |
rat |
| G R Stoner, L R Skirboll, S Werkman, D W Homme. Preferential effects of caffeine on limbic and cortical dopamine systems. Biological psychiatry. vol 23. issue 8. 1988-06-13. PMID:2835113. |
the dopamine antagonist haloperidol also antagonized the effects of caffeine. |
1988-06-13 |
2023-08-11 |
rat |
| M C Austin, P W Kaliva. The effect of cholinergic stimulation in the nucleus accumbens on locomotor behavior. Brain research. vol 441. issue 1-2. 1988-06-09. PMID:3359231. |
injection of the dopamine antagonist, haloperidol, prior to stimulation of the na with carbachol, significantly attenuated the motor stimulant effect of carbachol. |
1988-06-09 |
2023-08-11 |
rat |
| J A Joseph, S B Kandasamy, W A Hunt, T K Dalton, S Steven. Radiation-induced increases in sensitivity of cataleptic behavior to haloperidol: possible involvement of prostaglandins. Pharmacology, biochemistry, and behavior. vol 29. issue 2. 1988-06-09. PMID:3362928. |
in order to assess a possible action of prostaglandins and radiation on dopaminergic activity, the functioning of striatal dopaminergic autoreceptors was examined by determining the effects of varying concentrations of haloperidol on the k+-evoked release of dopamine from striatal slices obtained from parallel groups of animals treated as above. |
1988-06-09 |
2023-08-11 |
Not clear |
| J A Joseph, S B Kandasamy, W A Hunt, T K Dalton, S Steven. Radiation-induced increases in sensitivity of cataleptic behavior to haloperidol: possible involvement of prostaglandins. Pharmacology, biochemistry, and behavior. vol 29. issue 2. 1988-06-09. PMID:3362928. |
results indicated that sensitivity to haloperidol increased (higher k+-evoked dopamine release) in slices from irradiated or prostaglandin-treated animals and that this increase in sensitivity was blocked by indomethacin. |
1988-06-09 |
2023-08-11 |
Not clear |
| A Van Hest, F van Haaren, N E van de Pol. Haloperidol, but not apomorphine, differentially affects low response rates of male and female Wistar rats. Pharmacology, biochemistry, and behavior. vol 29. issue 3. 1988-06-09. PMID:3362947. |
in the second experiment, the same subjects were given different doses of haloperidol, which selectively blocks the post-synaptic dopamine receptors. |
1988-06-09 |
2023-08-11 |
human |
| V N Oksamitnyĭ, Z A Tamarov. [Depolarizing action of dopamine on the endings of the primary afferent fibers of an isolated segment of the spinal cord in rat pups]. Neirofiziologiia = Neurophysiology. vol 19. issue 6. 1988-06-08. PMID:3448491. |
haloperidol, a dopamine antagonist, decreased depolarization evoked by dopamine. |
1988-06-08 |
2023-08-11 |
rat |