| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| K Akiyama, M Sato, N Yamada, S Otsuk. Effect of chronic administration of haloperidol (intermittently) and haloperidol-decanoate (continuously) on D2 dopamine and muscarinic cholinergic receptors and on carbachol-stimulated phosphoinositide hydrolysis in the rat striatum. The Japanese journal of psychiatry and neurology. vol 41. issue 2. 1988-03-25. PMID:2830427. |
effect of chronic administration of haloperidol (intermittently) and haloperidol-decanoate (continuously) on d2 dopamine and muscarinic cholinergic receptors and on carbachol-stimulated phosphoinositide hydrolysis in the rat striatum. |
1988-03-25 |
2023-08-11 |
rat |
| b' P Sikiri\\xc4\\x87, I Rotkvi\\xc4\\x87, S Mise, S Krizanac, E Suchanek, M Petek, V Gjuris, J Geber, M Tu\\xc4\\x87an-Foreti\\xc4\\x87, I Udovici\\xc4\\x8. The influence of dopamine agonists and antagonists on gastric lesions in mice. European journal of pharmacology. vol 144. issue 2. 1988-03-25. PMID:3436369.' |
the dopamine agonist bromocriptine and l-dopa significantly inhibited whereas dopamine antagonist haloperidol aggravated the gastric lesions induced by pylorus ligation in mice as found earlier for rats. |
1988-03-25 |
2023-08-11 |
mouse |
| b' P Sikiri\\xc4\\x87, I Rotkvi\\xc4\\x87, S Mise, S Krizanac, E Suchanek, M Petek, V Gjuris, J Geber, M Tu\\xc4\\x87an-Foreti\\xc4\\x87, I Udovici\\xc4\\x8. The influence of dopamine agonists and antagonists on gastric lesions in mice. European journal of pharmacology. vol 144. issue 2. 1988-03-25. PMID:3436369.' |
furthermore, the successful use of a dopamine antagonist alone for the induction of gastric lesions also in mice was demonstrated, since the gastric lesions were induced by a single dose of haloperidol without any additional noxious treatment. |
1988-03-25 |
2023-08-11 |
mouse |
| B Costall, A M Domeney, R J Naylor, M B Tyer. Effects of the 5-HT3 receptor antagonist, GR38032F, on raised dopaminergic activity in the mesolimbic system of the rat and marmoset brain. British journal of pharmacology. vol 92. issue 4. 1988-03-22. PMID:2962686. |
5 the discontinuation of a concomitant 13 day intra-accumbens infusion of dopamine with haloperidol, 0.01 mg kg-1 i.p.t.d.s., caused a rebound hyperactivity. |
1988-03-22 |
2023-08-11 |
rat |
| J G Elferin. The effect of apomorphine on exocytosis and metabolic burst of polymorphonuclear leukocytes. British journal of pharmacology. vol 92. issue 4. 1988-03-22. PMID:3122866. |
2 the inhibitory effect of apomorphine was not prevented by the dopamine receptor antagonists haloperidol and pimozide, nor did dopamine itself inhibit fmet-leu-phe-induced exocytosis. |
1988-03-22 |
2023-08-11 |
rabbit |
| S Takeo, K Tanonaka, M Anan, S Hirag. Pharmacological actions of dopamine sulfoconjugate on cardiovascular system. Archives internationales de pharmacodynamie et de therapie. vol 289. issue 1. 1988-03-08. PMID:3435206. |
furthermore, dopamine 4-sulfate-induced increase in tension development, like that of dopamine itself, was inhibited by 0.3 microm phentolamine and 0.1 microm haloperidol. |
1988-03-08 |
2023-08-11 |
rat |
| L M Kachalova, N S Popov. [Principle of reorganizing the functional interrelations of brain structures in action on the dopamine system of dogs]. Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova. vol 37. issue 5. 1988-03-04. PMID:3433933. |
in dogs, the influence of chronic administration of the agonist (l-dopa) and antagonist (haloperidol) of central dopamine processes on functional interrelations of the brain structures was studied by dynamics of evoked potentials. |
1988-03-04 |
2023-08-11 |
Not clear |
| M J Bannon, P J Elliott, E B Bunne. Striatal tachykinin biosynthesis: regulation of mRNA and peptide levels by dopamine agonists and antagonists. Brain research. vol 427. issue 1. 1988-03-02. PMID:2448008. |
chronic administration of the prototypical dopamine antagonist haloperidol decreased striatal preprotachykinin mrna and nigral tachykinin peptides. |
1988-03-02 |
2023-08-11 |
rat |
| M J Bannon, P J Elliott, E B Bunne. Striatal tachykinin biosynthesis: regulation of mRNA and peptide levels by dopamine agonists and antagonists. Brain research. vol 427. issue 1. 1988-03-02. PMID:2448008. |
chronic treatment with the dopamine d2 receptor antagonist l-sulpiride (but not the inactive d-isomer) mimicked the effect of haloperidol. |
1988-03-02 |
2023-08-11 |
rat |
| G L Orr, J W Gole, H J Notman, R G Downe. Pharmacological characterisation of the dopamine-sensitive adenylate cyclase in cockroach brain: evidence for a distinct dopamine receptor. Life sciences. vol 41. issue 25. 1988-02-18. PMID:2892104. |
the octopamine-sensitive ac is inhibited by a variety of antagonists known to affect octopamine and dopamine receptors, with the following order of potency: mianserin greater than phentolamine greater than cyproheptadine greater than piflutixol greater than cis-flupentixol greater than sch-23390 greater than (+)-butaclamol greater than skf-83566 greater than sch-23388 greater than sulpiride greater than spiperone greater than haloperidol. |
1988-02-18 |
2023-08-11 |
Not clear |
| W H Baldridge, A K Ball, R G Mille. Dopaminergic regulation of horizontal cell gap junction particle density in goldfish retina. The Journal of comparative neurology. vol 265. issue 3. 1988-02-17. PMID:3693614. |
light- or dark-adapted goldfish (carassius auratus) retinas were treated with dopamine, which is believed to uncouple horizontal cells via d1 receptors, or with the dopamine antagonist haloperidol. |
1988-02-17 |
2023-08-11 |
Not clear |
| W H Baldridge, A K Ball, R G Mille. Dopaminergic regulation of horizontal cell gap junction particle density in goldfish retina. The Journal of comparative neurology. vol 265. issue 3. 1988-02-17. PMID:3693614. |
although the data suggests that there may be a reduction in axon terminal gap junction particle density with dopamine treatment, this effect is not reversible with haloperidol treatment. |
1988-02-17 |
2023-08-11 |
Not clear |
| A Michael-Titus, P Preterre, B Giros, J Costenti. Role of endogenous enkephalins in locomotion evidenced by acetorphan, an "enkephalinase" inhibitor. The Journal of pharmacology and experimental therapeutics. vol 243. issue 3. 1988-02-02. PMID:3121843. |
the increased locomotion was antagonized by a pretreatment with haloperidol or potentiated by gbr 12783, a potent and specific inhibitor of dopamine (da) uptake. |
1988-02-02 |
2023-08-11 |
mouse |
| D A Carter, S L Lightma. Oxytocin responses to stress in lactating and hyperprolactinaemic rats. Neuroendocrinology. vol 46. issue 6. 1988-02-02. PMID:3696384. |
hyperprolactinaemia produced by treatment with either dopamine antagonists (domperidone or haloperidol) or ovine prolactin was also associated with an impairment of the ot stress response in intact females, whereas domperidone treatment failed to modify the response in ovariectomized (ovx) rats. |
1988-02-02 |
2023-08-11 |
rat |
| H Satoh, T Kuwaki, K Shirakawa, Y Kohjimoto, T Ono, F Shibayama, Y Nomur. Effect of long-term dosing with tiapride on brain dopamine receptors and metabolism in rats. Comparative study with sulpiride and haloperidol. Japanese journal of pharmacology. vol 44. issue 4. 1988-01-15. PMID:3682405. |
the effects of long-term dosing with tiapride for 21 days on barin dopamine receptors and dopamine turnover were compared with those of sulpiride and haloperidol. |
1988-01-15 |
2023-08-11 |
rat |
| H Satoh, T Kuwaki, K Shirakawa, Y Kohjimoto, T Ono, F Shibayama, Y Nomur. Effect of long-term dosing with tiapride on brain dopamine receptors and metabolism in rats. Comparative study with sulpiride and haloperidol. Japanese journal of pharmacology. vol 44. issue 4. 1988-01-15. PMID:3682405. |
in these studies, tiapride and sulpiride were less active than haloperidol in the effects on brain dopamine receptors and dopamine turnover. |
1988-01-15 |
2023-08-11 |
rat |
| A Smiałowski, M Bija. Excitatory and inhibitory action of dopamine on hippocampal neurons in vitro. Involvement of D2 and D1 receptors. Neuroscience. vol 23. issue 1. 1988-01-11. PMID:2960914. |
having used selective dopaminergic agonists (pergolide and 2,3,4,5-tetrahydro-7,8-dihydroxy-1-phenyl-1h-3-benzazepines) and selective antagonists (haloperidol, spiperone, sulpiride and (r)-(+)-8-chloro-2,3,4,5-tetrahydro-3-methyl-5-phenyl-1h-3- benzazepine-7-ol), it was concluded that the excitation evoked by dopamine was due to activation of d2 dopamine receptors, while the inhibition was the result of d1 receptor activation. |
1988-01-11 |
2023-08-11 |
rat |
| A Studer, W Schult. The catecholamine uptake inhibitor nomifensine depresses impulse activity of dopamine neurons in mouse substantia nigra. Neuroscience letters. vol 80. issue 2. 1988-01-11. PMID:3683979. |
systemic administration of the catecholamine uptake inhibitor nomifensine (nom) in doses of 20-36 mg/kg strongly depressed the discharge rate of dopamine (da) neurons in the substantia nigra of mice for more than 2-3 h. this effect was fully reverted by the systemically administered da receptor antagonist haloperidol. |
1988-01-11 |
2023-08-11 |
mouse |
| T Nagao, H Suzuk. Non-neural electrical responses of smooth muscle cells of the rabbit basilar artery to electrical field stimulation. The Japanese journal of physiology. vol 37. issue 3. 1988-01-07. PMID:2890778. |
the depolarizing responses were resistant to tetrodotoxin, sympathetic transmission blocking agents (guanethidine, bretylium, or 6-hydroxydopamine treatment), receptor antagonists for 5-hydroxytryptamine (methysergide), dopamine (haloperidol), ach (atropine), noradrenaline (phentolamine), atp (alpha,beta-matp) or histamine (mepyramine), blockade of synthesis of prostaglandins or thromboxane a2 (indomethacin) or high mg2+, low ca2+ solution. |
1988-01-07 |
2023-08-11 |
rabbit |
| K Kistrup, J Gerlac. Selective D1 and D2 receptor manipulation in Cebus monkeys: relevance for dystonia and dyskinesia in humans. Pharmacology & toxicology. vol 61. issue 3. 1988-01-06. PMID:2891133. |
selective d1 and d2 dopamine (da) antagonists and agonists were given to 4 cebus monkeys who had previously received haloperidol treatment for 4 years. |
1988-01-06 |
2023-08-11 |
monkey |