| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R C Boldry, N J Uretsk. The importance of dopaminergic neurotransmission in the hypermotility response produced by the administration of N-methyl-D-aspartic acid into the nucleus accumbens. Neuropharmacology. vol 27. issue 6. 1988-10-17. PMID:2901677. |
this response is antagonized by drugs that interfere with dopaminergic neurotransmission, such as reserpine, alpha-methyl-p-tyrosine (ampt) and haloperidol, suggesting that nma may exert its effects by stimulating the release of dopamine (da) from nerve terminals. |
1988-10-17 |
2023-08-11 |
rat |
| A Fleischmann, G Urc. Clip-induced analgesia and immobility in the mouse: pharmacological characterization. Neuropharmacology. vol 27. issue 6. 1988-10-17. PMID:3419547. |
because both opiate and dopaminergic systems are usually implicated in analgesia and immobility, the pharmacological profile of clip-induced effects was compared to those elicited by the dopamine antagonist haloperidol, and by morphine. |
1988-10-17 |
2023-08-11 |
mouse |
| E S Prosser, J G Csernansky, L E Holliste. Differences in the time course of haloperidol-induced up-regulation of rat striatal and mesolimbic dopamine receptors. Life sciences. vol 43. issue 8. 1988-10-11. PMID:2901023. |
regional differences in the onset and persistence of increased dopamine d2 receptor density in rat brain were studied following daily injections of haloperidol for 3, 7, 14, or 28 days. |
1988-10-11 |
2023-08-11 |
rat |
| J M Monti, M Hawkins, H Jantos, L D'Angelo, M Fernánde. Biphasic effects of dopamine D-2 receptor agonists on sleep and wakefulness in the rat. Psychopharmacology. vol 95. issue 3. 1988-10-11. PMID:3137628. |
the effects of the dopamine (da) receptor agonists apomorphine, bromocriptine and pergolide were compared with those produced by a da receptor antagonist, haloperidol, in rats implanted with electrodes for chronic sleep recordings. |
1988-10-11 |
2023-08-11 |
rat |
| M K Menon, L I Gordon, C K Kodama, J Fitte. Influence of D-1 receptor system on the D-2 receptor-mediated hypothermic response in mice. Life sciences. vol 43. issue 10. 1988-10-07. PMID:2901020. |
the hypothermia induced by apomorphine, a mixed dopamine (da) agonist in male swiss-webster mice, was not blocked by the selective d-1 antagonist sch 23390 but was completely blocked by the selective d-2 antagonists haloperidol, sulpiride and ym-09151-2. |
1988-10-07 |
2023-08-11 |
mouse |
| A J MacLennan, S Atmadja, N Lee, H C Fibige. Chronic haloperidol administration increases the density of D2 dopamine receptors in the medial prefrontal cortex of the rat. Psychopharmacology. vol 95. issue 2. 1988-10-04. PMID:3137606. |
chronic haloperidol administration increases the density of d2 dopamine receptors in the medial prefrontal cortex of the rat. |
1988-10-04 |
2023-08-11 |
rat |
| J E Leysen, W Gommeren, P F Janssen, P Van Gompel, P A Jansse. Receptor interactions of dopamine and serotonin antagonists: binding in vitro and in vivo and receptor regulation. Psychopharmacology series. vol 5. 1988-10-03. PMID:3045796. |
in this article, we will illustrate the three stages of investigation of receptor interactions and discuss the relevance and importance of the findings, using as examples three drugs known in psychopharmacological research: (a) the neuroleptic haloperidol, a prototype of a dopamine d2 antagonist: (b) setoperone, a potential antipsychotic agent with very potent serotonin s2 and moderate d2 antagonistic activity (ceulemans et al. |
1988-10-03 |
2023-08-11 |
Not clear |
| D D Kharkevic. [Effect of dopamine on the antitumor immunity of patients with breast cancer]. Farmakologiia i toksikologiia. vol 51. issue 3. 1988-09-27. PMID:3410039. |
it was shown that the stimulating effect of dopamine revealed at concentrations of 10(-7)-10(-5) m was blocked by haloperidol (10(-6) m). |
1988-09-27 |
2023-08-11 |
Not clear |
| O Magnusson, C J Fowler, B Mohringe, A Wijkström, S O Ogre. Comparison of the effects of haloperidol, remoxipride and raclopride on "pre"- and postsynaptic dopamine receptors in the rat brain. Naunyn-Schmiedeberg's archives of pharmacology. vol 337. issue 4. 1988-09-16. PMID:2900472. |
comparison of the effects of haloperidol, remoxipride and raclopride on "pre"- and postsynaptic dopamine receptors in the rat brain. |
1988-09-16 |
2023-08-11 |
rat |
| O Magnusson, C J Fowler, B Mohringe, A Wijkström, S O Ogre. Comparison of the effects of haloperidol, remoxipride and raclopride on "pre"- and postsynaptic dopamine receptors in the rat brain. Naunyn-Schmiedeberg's archives of pharmacology. vol 337. issue 4. 1988-09-16. PMID:2900472. |
the ability of the dopamine receptor antagonists haloperidol, raclopride and remoxipride to prevent the b-ht 920-induced decrease in striatal and limbic l-dopa accumulation in gamma-butyrolactone (gbl)- and nsd 1015-treated rats (termed 'gbl-reversal') was used to define the effects of these compounds on "presynaptic" dopamine receptors. |
1988-09-16 |
2023-08-11 |
rat |
| O Magnusson, C J Fowler, B Mohringe, A Wijkström, S O Ogre. Comparison of the effects of haloperidol, remoxipride and raclopride on "pre"- and postsynaptic dopamine receptors in the rat brain. Naunyn-Schmiedeberg's archives of pharmacology. vol 337. issue 4. 1988-09-16. PMID:2900472. |
the potencies of haloperidol, raclopride and remoxipride in the gbl model were compared with their potencies in behavioural models for postsynaptic dopamine receptors. |
1988-09-16 |
2023-08-11 |
rat |
| B H Westerink, H M Hofsteede, G Damsma, J B de Vrie. The significance of extracellular calcium for the release of dopamine, acetylcholine and amino acids in conscious rats, evaluated by brain microdialysis. Naunyn-Schmiedeberg's archives of pharmacology. vol 337. issue 4. 1988-09-16. PMID:2970014. |
magnesium infusion was also most effective in preventing drug-evoked voltage-dependent dopamine release (induced by coadministration of haloperidol and gbr 12909). |
1988-09-16 |
2023-08-11 |
rat |
| K Nowak, S Welsch-Kunze, K Kuschinsk. Conditioned tolerance to haloperidol- and droperidol-induced catalepsy. Naunyn-Schmiedeberg's archives of pharmacology. vol 337. issue 4. 1988-09-16. PMID:3405313. |
the dopamine turnover in striatum or nucleus accumbens after administration of 1.5 mg/kg of haloperidol i.p. |
1988-09-16 |
2023-08-11 |
rat |
| J C Jaen, L D Wise, T G Heffner, T A Pugsley, L T Meltze. Dopamine autoreceptor agonists as potential antipsychotics. 1. (Aminoalkoxy)anilines. Journal of medicinal chemistry. vol 31. issue 8. 1988-09-02. PMID:2899647. |
one of these compounds, 3-[3-(4-phenyl-1-piperazinyl)propoxy]benzenamine (4c), has been identified as a selective dopamine (da) autoreceptor agonist in tests that include [3h]haloperidol binding, inhibition of striatal da synthesis, inhibition of da neuronal firing, inhibition of spontaneous locomotor activity, and reversal of reserpine-induced depression in rats. |
1988-09-02 |
2023-08-11 |
rat |
| T Sawaguchi, M Matsumura, K Kubot. Dopamine enhances the neuronal activity of spatial short-term memory task in the primate prefrontal cortex. Neuroscience research. vol 5. issue 5. 1988-08-31. PMID:3399149. |
iontophoretically applied dopamine enhanced the delay-related neuronal activity, while fluphenazine and haloperidol attenuated the activity. |
1988-08-31 |
2023-08-11 |
monkey |
| G Di Chiara, A Imperat. Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats. Proceedings of the National Academy of Sciences of the United States of America. vol 85. issue 14. 1988-08-24. PMID:2899326. |
haloperidol, a neuroleptic drug, increased extracellular dopamine concentrations, but this effect was not preferential for the accumbens and was associated with hypomotility and sedation. |
1988-08-24 |
2023-08-11 |
rat |
| W H Chang, T Y Chen, C F Lee, J C Hung, W H Hu, E K Ye. Plasma homovanillic acid levels and subtyping of schizophrenia. Psychiatry research. vol 23. issue 3. 1988-08-11. PMID:3387499. |
plasma levels of homovanillic acid (hva), a major metabolite of dopamine, were measured in a group of 24 schizophrenic inpatients before and during 6 weeks of haloperidol (hal) treatment. |
1988-08-11 |
2023-08-11 |
Not clear |
| K Yamaguchi, T Karakida, M Koike, H Ham. Central effects of catecholamine antagonists on angiotensin-induced vasopressin secretion in conscious rats. Acta endocrinologica. vol 118. issue 1. 1988-08-04. PMID:3389051. |
the plasma avp responses to both dopamine and ang ii were significantly (p less than 0.01) inhibited by haloperidol (a dopamine blocker, 0.15 mumol) given 10 min before administration of these agents. |
1988-08-04 |
2023-08-11 |
rat |
| F van Valen, E Kec. Induction of glycogenolysis in cultured Ewing's sarcoma cells by dopamine and beta-adrenergic agonists. Journal of cancer research and clinical oncology. vol 114. issue 3. 1988-08-02. PMID:2898475. |
glycogenolysis induced by dopamine was blocked by chlorpromazine, a dopamine d1-receptor antagonist, but not by haloperidol, a dopamine d2-receptor antagonist. |
1988-08-02 |
2023-08-11 |
Not clear |
| L H Jiang, M Tsai, R Y Wan. Chronic treatment with high doses of haloperidol fails to decrease the time course for the development of depolarization inactivation of midbrain dopamine neurons. Life sciences. vol 43. issue 1. 1988-08-01. PMID:3386416. |
chronic treatment with high doses of haloperidol fails to decrease the time course for the development of depolarization inactivation of midbrain dopamine neurons. |
1988-08-01 |
2023-08-11 |
rat |