| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S M Sorensen, T M Humphreys, M G Palfreyma. Effect of acute and chronic MDL 73,147EF, a 5-HT3 receptor antagonist, on A9 and A10 dopamine neurons. European journal of pharmacology. vol 163. issue 1. 1989-08-21. PMID:2744086. |
haloperidol, but not mdl 73,147ef, given acutely increased the number of active dopamine neurons in the substantia nigra (a9). |
1989-08-21 |
2023-08-11 |
rabbit |
| S M Sorensen, T M Humphreys, M G Palfreyma. Effect of acute and chronic MDL 73,147EF, a 5-HT3 receptor antagonist, on A9 and A10 dopamine neurons. European journal of pharmacology. vol 163. issue 1. 1989-08-21. PMID:2744086. |
both haloperidol and mdl 73,147ef, given chronically, decreased the number of active ventral tegmental dopamine neurons and the number of active a9 dopamine neurons. |
1989-08-21 |
2023-08-11 |
rabbit |
| J Hietal. Effects of DA-1- and DA-2-dopamine antagonists on apomorphine-induced inhibition of peripheral sympathetic neurotransmission. Journal of autonomic pharmacology. vol 8. issue 4. 1989-08-18. PMID:2855331. |
the rank order of potency of the dopamine antagonists was domperidone greater than fluphenazine greater than or equal to (-)-sulpiride greater than or equal to haloperidol greater than (+)-sulpiride much greater than sch 23390. |
1989-08-18 |
2023-08-11 |
rat |
| S A Kolenik, F J Hoffman, M B Bower. Regional homovanillic acid levels and oral movements in rats following chronic haloperidol treatment. Psychopharmacology. vol 98. issue 3. 1989-08-17. PMID:2501819. |
rats with more severe orofacial movements after 51 days of haloperidol administration showed lower levels of the dopamine metabolite homovanillic acid (hva) in the caudate compared to animals who did not develop significant mouth movements. |
1989-08-17 |
2023-08-11 |
rat |
| R J Niesink, J M Van Re. Involvement of opioid and dopaminergic systems in isolation-induced pinning and social grooming of young rats. Neuropharmacology. vol 28. issue 4. 1989-08-17. PMID:2546087. |
some of the effects were partially antagonized by the dopamine antagonist haloperidol, and the neurolepticum-like peptide, desenkephalin-gamma-endorphin (de-gamma-e). |
1989-08-17 |
2023-08-11 |
rat |
| D Duterte-Boucher, C Panissaud, A Michael-Titus, J Costenti. Stimulation of central D1 dopamine receptors reverses reserpine-induced hypothermia in mice. Neuropharmacology. vol 28. issue 4. 1989-08-17. PMID:2568597. |
in reserpine-pretreated mice, the dopamine (da) agonist apomorphine, which stimulates both the d1 and d2 subtypes of da receptors, increases body temperature according to a mechanism insensitive to the specific d2 da antagonist sulpiride (horowski 1978) or the preferential d2 da antagonist haloperidol (danielson, coutts, keashly and tang 1985). |
1989-08-17 |
2023-08-11 |
mouse |
| J G Pfaus, A G Phillip. Differential effects of dopamine receptor antagonists on the sexual behavior of male rats. Psychopharmacology. vol 98. issue 3. 1989-08-17. PMID:2568656. |
in the present experiments, the dose-response effects of the dopamine (da) receptor antagonists haloperidol, pimozide, clozapine, sulpiride, and metoclopramide, were assessed on patterns of copulatory behavior in intact, sexually active male rats with a high level of sexual experience and performance. |
1989-08-17 |
2023-08-11 |
rat |
| R Halperin, J J Guerin, K L Davi. Regional differences in the induction of behavioral supersensitivity by prolonged treatment with atypical neuroleptics. Psychopharmacology. vol 98. issue 3. 1989-08-17. PMID:2568659. |
this study examined the effect of chronic administration of haloperidol, clozapine, sulpiride and metoclopramide on stereotypy and locomotor activity elicited by direct injection of dopamine in to the striatum or nucleus accumbens, respectively. |
1989-08-17 |
2023-08-11 |
rat |
| E A Singer, G Cichini, B Valenta, O Kraup. Effects of urapidil on catecholamine turnover and release in the central nervous system of the rat. The Journal of pharmacy and pharmacology. vol 41. issue 3. 1989-08-16. PMID:2568444. |
the actions of urapidil, prazosin, idazoxan, and haloperidol on the turnover of noradrenaline in the hypothalamus and dopamine in the nucleus accumbens of the rat were investigated using changes in the ratios of 3-methoxy-4-hydroxyphenyl-glycol/noradrenaline (mhpg/na) and 3,4-dihydroxyphenylacetic acid/dopamine (dopac/da), respectively, as measures for drug-induced effects. |
1989-08-16 |
2023-08-11 |
rat |
| Y Imazu, K Kobayashi, T Shohmor. Comparative study of sulpiride and haloperidol on dopamine turnover in the rat brain. Neurochemical research. vol 14. issue 5. 1989-08-15. PMID:2747836. |
comparative study of sulpiride and haloperidol on dopamine turnover in the rat brain. |
1989-08-15 |
2023-08-11 |
rat |
| Y Imazu, K Kobayashi, T Shohmor. Comparative study of sulpiride and haloperidol on dopamine turnover in the rat brain. Neurochemical research. vol 14. issue 5. 1989-08-15. PMID:2747836. |
the effects of the neuroleptics, sulpiride and haloperidol, on dopamine (da) turnover were compared following the acute and chronic administration of these drugs alone or in combination with levodopa or apomorphine. |
1989-08-15 |
2023-08-11 |
rat |
| C K Meshul, D E Case. Regional, reversible ultrastructural changes in rat brain with chronic neuroleptic treatment. Brain research. vol 489. issue 2. 1989-08-11. PMID:2568156. |
administration of the dopamine receptor antagonist (neuroleptic, antipsychotic), haloperidol, resulting in an increase in the number of dopamine binding sites in the striatum and nucleus accumbens, has been well established. |
1989-08-11 |
2023-08-11 |
rat |
| R Marrannes, A Wauquie. Episodic barrel rotations induced by intrastriatal injection of quinolinic acid in rats. Inhibition by anticonvulsants. Pharmacology, biochemistry, and behavior. vol 31. issue 1. 1989-08-08. PMID:2978064. |
in order to assess whether this test is also sensitive to drugs influencing the symptoms of huntington's disease, the effect of the dopamine antagonists haloperidol and pimozide, the acetylcholinesterase inhibitor physostigmine and the anticholinergics atropine and dexetimide were investigated as well. |
1989-08-08 |
2023-08-11 |
rat |
| E A Pehek, J T Thompson, R C Eaton, T J Bazzett, E M Hul. Apomorphine and haloperidol, but not domperidone, affect penile reflexes in rats. Pharmacology, biochemistry, and behavior. vol 31. issue 1. 1989-08-08. PMID:3252251. |
haloperidol, a centrally-acting dopamine antagonist, either blocked the effects produced by apomorphine administration, or had actions opposite to those of apomorphine. |
1989-08-08 |
2023-08-11 |
rat |
| G Bissette, W T Dauer, C D Kilts, L O'Connor, C B Nemerof. The effect of the stereoisomers of butaclamol on neurotensin content in discrete regions of the rat brain. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 1. issue 4. 1989-08-04. PMID:2472151. |
moreover, we sought to determine whether the effects of haloperidol on nt concentrations can be antagonized by concomitant administration of an indirect dopamine agonist, d-amphetamine. |
1989-08-04 |
2023-08-11 |
rat |
| L Hernandez, B G Hoebe. Haloperidol given chronically decreases basal dopamine in the prefrontal cortex more than the striatum or nucleus accumbens as simultaneously measured by microdialysis. Brain research bulletin. vol 22. issue 4. 1989-08-01. PMID:2736403. |
haloperidol given chronically decreases basal dopamine in the prefrontal cortex more than the striatum or nucleus accumbens as simultaneously measured by microdialysis. |
1989-08-01 |
2023-08-11 |
rat |
| L Hernandez, B G Hoebe. Haloperidol given chronically decreases basal dopamine in the prefrontal cortex more than the striatum or nucleus accumbens as simultaneously measured by microdialysis. Brain research bulletin. vol 22. issue 4. 1989-08-01. PMID:2736403. |
extracellular dopamine (da), dihydroxyphenylacetic acid (dopac), and homovanillic acid (hva) were measured in response to acute and chronic haloperidol, an antipsychotic drug. |
1989-08-01 |
2023-08-11 |
rat |
| A R Wakade, T D Wakade, S V Bhave, R K Malhotr. Demonstration of adrenergic and dopaminergic receptors in cultured sympathetic neurons--their coupling to cAMP but not to the transmitter release process. Neuroscience. vol 27. issue 3. 1989-08-01. PMID:2855258. |
dopamine did not affect neuronal cyclic 3',5'-adenosine monophosphate content, but forskolin-stimulated increase in cyclic 3',5'-adenosine monophosphate was further facilitated by dopamine, and this effect was blocked by haloperidol. |
1989-08-01 |
2023-08-11 |
chicken |
| M D Schechte. Serotonergic-dopaminergic mediation of 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy"). Pharmacology, biochemistry, and behavior. vol 31. issue 4. 1989-08-01. PMID:2908067. |
the serotonin antagonist pirenperone significantly decreased mdma discrimination, whereas the dopamine decreasing drugs cgs 10746b and haloperidol had no effect. |
1989-08-01 |
2023-08-11 |
human |
| K Niijima, M Yoshid. Activation of mesencephalic dopamine neurons by chemical stimulation of the nucleus tegmenti pedunculopontinus pars compacta. Brain research. vol 451. issue 1-2. 1989-07-31. PMID:3251582. |
the rate of the tpc-derived circling was significantly attenuated by blocking agents of dopamine systems, including haloperidol and alpha-methyl-tyrosine (both injected intraperitoneally) and also 6-hydroxydopamine (injected into the bilateral medial forebrain bundles). |
1989-07-31 |
2023-08-11 |
rat |