| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| B Caronti, F Passarelli, C Calderaro, G Palladini, F E Pontier. Effects of haloperidol on the expression of lymphocyte dopamine receptor mRNAs in the rat. Progress in neuro-psychopharmacology & biological psychiatry. vol 23. issue 5. 1999-12-02. PMID:10509379. |
these results indicate short-lasting dynamic changes of expression of lymphocyte d1b dopamine receptor mrna by haloperidol and suggest that the effects of dopamine and dopaminergic drugs on the immune system might be mediated, at least in part, by direct interaction of these substances with dopamine receptors on lymphocyte membrane. |
1999-12-02 |
2023-08-12 |
rat |
| I S Midzianovskai. [Two types of "spike-wave" discharges in the electrocorticogram of WAG/Rij rats, the genetic model of absence epilepsy]. Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova. vol 49. issue 5. 1999-12-01. PMID:10570541. |
since it has been shown earlier that haloperidol, which acts on dopamine receptors oppositely to apomorphine, enhance the generalized spike-wave activity and suppress the local discharges. |
1999-12-01 |
2023-08-12 |
rat |
| E Jakubowska-Doğr. Modification of avoidance responding by amphetamine and dopamine receptor antagonists. Polish journal of pharmacology. vol 51. issue 4. 1999-11-30. PMID:10540961. |
this study was designed to investigate the effects of preferential d1 (sch 23390) and d2 (haloperidol) dopamine (da) receptor antagonists and their interaction with low-dose (1 mg kg) d-amphetamine during the acquisition of two-way shuttle avoidance in rats. |
1999-11-30 |
2023-08-12 |
rat |
| E H Chartoff, R P Ward, D M Dors. Role of adenosine and N-methyl-D-aspartate receptors in mediating haloperidol-induced gene expression and catalepsy. The Journal of pharmacology and experimental therapeutics. vol 291. issue 2. 1999-11-24. PMID:10525068. |
acute blockade of dopamine d(2) receptors by the typical antipsychotic drug haloperidol leads to alterations in neuronal gene expression and behavior. |
1999-11-24 |
2023-08-12 |
Not clear |
| S J Gladwell, J H Coot. Fast excitatory post synaptic potentials and their response to catecholaminergic antagonists in rat sympathetic preganglionic neurones in vitro. Neuroscience letters. vol 268. issue 2. 1999-11-22. PMID:10400085. |
the latter potential was blocked with the dopamine d2 antagonist haloperidol but not with the dopamine d1 antagonist sch 23390. |
1999-11-22 |
2023-08-12 |
rat |
| A Nakazato, Y Sekiguchi, K Ohta, S Chaki, S Okuyam. Chemical modification of apomorphine to discover sigma ligands: 6H-dibenzo[b,d]pyran and carbazole analogues. Bioorganic & medicinal chemistry. vol 7. issue 9. 1999-11-18. PMID:10530952. |
we focused on a difference in structural flexibility between haloperidol and apomorphine, and studied chemical modification of apomorphine, a compound with high affinity for dopamine d2 receptors but not for sigma receptors, for discovery of sigma ligands. |
1999-11-18 |
2023-08-12 |
Not clear |
| N Jelovac, P Sikiric, R Rucman, M Petek, A Marovic, D Perovic, S Seiwerth, S Mise, B Turkovic, G Dodig, P Miklic, G Buljat, I Prkaci. Pentadecapeptide BPC 157 attenuates disturbances induced by neuroleptics: the effect on catalepsy and gastric ulcers in mice and rats. European journal of pharmacology. vol 379. issue 1. 1999-11-15. PMID:10499368. |
in other experiments, considering the gastric origin of this pentadecapeptide, the focus was shifted to the evidence that a dose of haloperidol, cataleptogenic due to dopamine receptors blockade, induces gastric ulcers in rats. |
1999-11-15 |
2023-08-12 |
mouse |
| C C Chinen, R Frussa-Filh. Conditioning to injection procedures and repeated testing increase SCH 23390-induced catalepsy in mice. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 21. issue 5. 1999-11-15. PMID:10516963. |
this "injection-conditioned catalepsy" was also observed after repeated treatment with the dopamine d2 antagonists, haloperidol and metoclopramide. |
1999-11-15 |
2023-08-12 |
mouse |
| L J Bryan-Lluka, G A Siebert, S M Pon. Potencies of haloperidol metabolites as inhibitors of the human noradrenaline, dopamine and serotonin transporters in transfected COS-7 cells. Naunyn-Schmiedeberg's archives of pharmacology. vol 360. issue 2. 1999-11-08. PMID:10494878. |
potencies of haloperidol metabolites as inhibitors of the human noradrenaline, dopamine and serotonin transporters in transfected cos-7 cells. |
1999-11-08 |
2023-08-12 |
human |
| L J Bryan-Lluka, G A Siebert, S M Pon. Potencies of haloperidol metabolites as inhibitors of the human noradrenaline, dopamine and serotonin transporters in transfected COS-7 cells. Naunyn-Schmiedeberg's archives of pharmacology. vol 360. issue 2. 1999-11-08. PMID:10494878. |
in this study, the hypothesis was partially investigated by determining the potencies of haloperidol and reduced haloperidol and the corresponding pyridinium and tetrahydropyridine metabolites, compared with mpp+ and mptp, as inhibitors of the noradrenaline transporter (nat), dopamine transporter (dat) and 5-ht transporter (sert). |
1999-11-08 |
2023-08-12 |
human |
| J M Stern, S E Kee. Maternal motivation of lactating rats is disrupted by low dosages of haloperidol. Behavioural brain research. vol 99. issue 2. 1999-10-27. PMID:10512589. |
motorically-active maternal behaviors of rats, such as retrieval and licking of pups, are known to be reduced or suspended following systemic injection of > or = 0.2 mg/kg haloperidol (hal), a dopamine (da) receptor blocker. |
1999-10-27 |
2023-08-12 |
rat |
| B A Morrow, S J Rosenberg, R H Rot. Chronic clozapine, but not haloperidol, alters the response of mesoprefrontal dopamine neurons to stress and clozapine challenges in rats. Synapse (New York, N.Y.). vol 34. issue 1. 1999-10-20. PMID:10459169. |
chronic clozapine, but not haloperidol, alters the response of mesoprefrontal dopamine neurons to stress and clozapine challenges in rats. |
1999-10-20 |
2023-08-12 |
rat |
| B A Morrow, S J Rosenberg, R H Rot. Chronic clozapine, but not haloperidol, alters the response of mesoprefrontal dopamine neurons to stress and clozapine challenges in rats. Synapse (New York, N.Y.). vol 34. issue 1. 1999-10-20. PMID:10459169. |
rats treated for 21 days with clozapine or haloperidol, a typical antipsychotic without significant binding affinity for serotonergic receptors, showed lowered basal dopamine metabolism in the medial prefrontal cortex, the nucleus accumbens, and the striatum, as expected. |
1999-10-20 |
2023-08-12 |
rat |
| B A Morrow, S J Rosenberg, R H Rot. Chronic clozapine, but not haloperidol, alters the response of mesoprefrontal dopamine neurons to stress and clozapine challenges in rats. Synapse (New York, N.Y.). vol 34. issue 1. 1999-10-20. PMID:10459169. |
when corrected for baseline differences, both challenges significantly elevated dopamine metabolism in the prefrontal cortex of the clozapine group more than the saline or haloperidol groups. |
1999-10-20 |
2023-08-12 |
rat |
| S Chaki, T Funakoshi, R Yoshikawa, S Okuyama, T Kumagai, A Nakazato, M Nagamine, K Tomisaw. In vivo receptor occupancy of NRA0045, a putative atypical antipsychotic, in rats. Neuropharmacology. vol 38. issue 8. 1999-10-12. PMID:10462131. |
in the present study, in vivo receptor occupancy of 5-ht2a, alpha1, dopamine d2 and d3 receptors by nra0045 was assessed, based on in vivo and ex vivo receptor binding, and findings were compared to reference antipsychotic drugs (haloperidol, risperidone, clozapine). |
1999-10-12 |
2023-08-12 |
rat |
| S Chaki, T Funakoshi, R Yoshikawa, S Okuyama, T Kumagai, A Nakazato, M Nagamine, K Tomisaw. In vivo receptor occupancy of NRA0045, a putative atypical antipsychotic, in rats. Neuropharmacology. vol 38. issue 8. 1999-10-12. PMID:10462131. |
intraperitoneal administration of haloperidol highly occupied the dopamine d2 receptor in the striatum and nucleus accumbens, and alpha1 adrenoceptors in the frontal cortex. |
1999-10-12 |
2023-08-12 |
rat |
| A Ceci, A Brambilla, P Duranti, M Grauert, N Grippa, F Borsin. Effect of antipsychotic drugs and selective dopaminergic antagonists on dopamine-induced facilitatory activity in prelimbic cortical pyramidal neurons. An in vitro study. Neuroscience. vol 93. issue 1. 1999-10-08. PMID:10430475. |
the facilitatory effect of dopamine in prelimbic cortex was concentration dependently antagonized by haloperidol, risperidone, quetiapine, clozapine and by the selective d4 dopaminergic receptor antagonist l-745,870, but not by the selective d2/d3 dopaminergic receptor antagonist (-)-sulpiride. |
1999-10-08 |
2023-08-12 |
Not clear |
| D Wirtshafter, K E Asi. Haloperidol induces Fos expression in the globus pallidus and substantia nigra of cynomolgus monkeys. Brain research. vol 835. issue 2. 1999-09-28. PMID:10415370. |
systemic injections of the dopamine antagonist haloperidol (0.1-2.5 mg/kg) induced a dose dependent increase in fos-like immunoreactivity (fli) in the internal segment of the globus pallidus (gpi) and in the substantia nigra (sn) of cynomolgus monkeys. |
1999-09-28 |
2023-08-12 |
monkey |
| M S Gevaerd, R N Takahash. Involvement of dopamine receptors on locomotor stimulation and sensitization elicited by the interaction of ethanol and mazindol in mice. Pharmacology, biochemistry, and behavior. vol 63. issue 3. 1999-09-14. PMID:10418779. |
male swiss albino mice were treated daily for 7 days with combined etoh+mz (1.2 g/kg, 5.0 mg/kg ip), etoh (1.2 g/kg ip), mz (5.0 mg/kg ip), or control solution coadministered with the d1 dopamine antagonist sch-23390 (0.025 or 0.05 mg/kg ip), the mixed dopamine antagonist haloperidol (0.05 or 0.075 mg/kg ip), or vehicle. |
1999-09-14 |
2023-08-12 |
mouse |
| M Mavridis, M J Besso. Dopamine-opiate interaction in the regulation of neostriatal and pallidal neuronal activity as assessed by opioid precursor peptides and glutamate decarboxylase messenger RNA expression. Neuroscience. vol 92. issue 3. 1999-09-09. PMID:10426535. |
the expression of the messenger rnas encoding glutamate decarboxylase-the biosynthetic enzyme of gaba-and the precursor peptides of enkephalin (preproenkephalin) and dynorphin (preprodynorphin) were measured in rats after a sustained blockade of opioid receptors by naloxone (s.c. implanted osmotic minipump, eight days, 3 mg/kg per h), and/or a subchronic blockade of d2 dopamine receptors by haloperidol (one week, 1.25 mg/kg s.c. twice a day). |
1999-09-09 |
2023-08-12 |
rat |