| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C L Nilsson, M Hellstrand, A Ekman, E Eriksso. Both dopamine and the putative dopamine D3 receptor antagonist PNU-99194A induce a biphasic inhibition of phorbol ester-stimulated arachidonic acid release from CHO cells transfected with the dopamine D3 receptor. Life sciences. vol 64. issue 11. 1999-04-21. PMID:10201643. |
the effect of dopamine -- which was antagonized by pretreatment with pertussis toxin (ptx) or by the dopamine receptor antagonist haloperidol -- was biphasic; thus, at increasing concentrations of dopamine (100 nm - 1 microm), aa levels approached baseline. |
1999-04-21 |
2023-08-12 |
Not clear |
| J Rehman, A Kaynan, G Christ, M Valcic, S Maayani, A Melma. Modification of sexual behavior of Long-Evans male rats by drugs acting on the 5-HT1A receptor. Brain research. vol 821. issue 2. 1999-04-13. PMID:10064829. |
two butyrophenone analogs, spiperone (a 5-ht1a and dopamine d2 antagonist) and haloperidol (a d2 antagonist), were also tested for their interaction with dpat. |
1999-04-13 |
2023-08-12 |
rat |
| T L Lee, C T Hsu, S T Yen, C W Lai, J T Chen. Activation of beta3-adrenoceptors by exogenous dopamine to lower glucose uptake into rat adipocytes. Journal of the autonomic nervous system. vol 74. issue 2-3. 1999-04-07. PMID:9915622. |
dopamine induced a concentration-dependent decrease of 2-dg uptake into adipocytes in a manner which was not modified by haloperidol at concentrations sufficient to block dopaminergic receptors. |
1999-04-07 |
2023-08-12 |
rat |
| K Kawasak. [Preretinopathic changes in the oscillatory potential in diabetic retina: interpretation and significance]. Nippon Ganka Gakkai zasshi. vol 102. issue 12. 1999-03-30. PMID:10025114. |
5) the amplitude of the op is enhanced by dopamine and nomifensine (a potent dopamine-uptake blocker), and diminished by haloperidol (a potent antagonist to dopamine d1-d2 receptors). |
1999-03-30 |
2023-08-12 |
rat |
| C Cohen, G Perrault, D J Sange. Preferential involvement of D3 versus D2 dopamine receptors in the effects of dopamine receptor ligands on oral ethanol self-administration in rats. Psychopharmacology. vol 140. issue 4. 1999-03-29. PMID:9888624. |
this conclusion was further supported by the finding that pretreatment with the d2/d3 dopamine antagonists, haloperidol (0.1-0.4 mg/kg) and tiapride (10-60 mg/kg), decreased responding for ethanol at doses which have been shown previously to block dopamine transmission. |
1999-03-29 |
2023-08-12 |
rat |
| F X Vollenweider, M F Vollenweider-Scherpenhuyzen, A Bäbler, H Vogel, D Hel. Psilocybin induces schizophrenia-like psychosis in humans via a serotonin-2 agonist action. Neuroreport. vol 9. issue 17. 1999-03-24. PMID:9875725. |
in healthy human volunteers, the psychotomimetic effects of psilocybin were blocked dose-dependently by the serotonin-2a antagonist ketanserin or the atypical antipsychotic risperidone, but were increased by the dopamine antagonist and typical antipsychotic haloperidol. |
1999-03-24 |
2023-08-12 |
human |
| W R Wu, X Z Zh. The amphetamine-like reinforcing effect and mechanism of L-deprenyl on conditioned place preference in mice. European journal of pharmacology. vol 364. issue 1. 1999-03-22. PMID:9920178. |
pretreatment with the dopamine antagonist, haloperidol (1 mg/kg i.p. |
1999-03-22 |
2023-08-12 |
mouse |
| A M Gray, J H Connic. Clozapine-induced dopamine levels in the rat striatum and nucleus accumbens are not affected by muscarinic antagonism. European journal of pharmacology. vol 362. issue 2-3. 1999-03-18. PMID:9874162. |
the effect of the muscarinic antagonist, scopolamine, was examined for a change in the increase in extracellular dopamine, dihydroxyphenyl acetic acid (dopac), homovanillic acid (hva) and 5-hydroxyindolacetic acid (5-hiaa), induced by haloperidol or clozapine in the striatum and nucleus accumbens of anaesthetised and awake rats, monitored using in vivo cerebral microdialysis. |
1999-03-18 |
2023-08-12 |
rat |
| A Amer. Effects of the Aconitum alkaloid songorine on synaptic transmission and paired-pulse facilitation of CA1 pyramidal cells in rat hippocampal slices. British journal of pharmacology. vol 125. issue 3. 1999-03-04. PMID:9806328. |
however, the effect of songorine was completely abolished by the selective dopamine d2 receptor antagonist sulpiride (0.1 microm) as well as by haloperidol (10 microm) and was mimicked by application of the dopamine releaser, amantadine (100 mm). |
1999-03-04 |
2023-08-12 |
rat |
| B H Westerink, P de Boer, J B de Vries, C G Kruse, S K Lon. Antipsychotic drugs induce similar effects on the release of dopamine and noradrenaline in the medial prefrontal cortex of the rat brain. European journal of pharmacology. vol 361. issue 1. 1999-03-04. PMID:9851538. |
in the present study we have compared the effects of the classical antipsychotic drug haloperidol and four different atypical antipsychotics (clozapine, risperidone, olanzapine, ziprasidone) on extracellular levels of dopamine and noradrenaline in the medial prefrontal cortex (mpfc) of conscious rats. |
1999-03-04 |
2023-08-12 |
rat |
| R J Wyatt, F Karoum, J Masseran. Effects of antipsychotics, vitamin E, and MK-801 on dopamine dynamics in the rat brain following discontinuation of cocaine. Psychiatry research. vol 80. issue 3. 1999-02-25. PMID:9796937. |
in addition to the potential value these findings have for further understanding cocaine abuse, it is proposed that the alteration in dopamine metabolism produced by cocaine, and the ability of haloperidol, clozapine and vitamin e to decrease cocaine's effects, model some biochemical aspects of schizophrenia. |
1999-02-25 |
2023-08-12 |
rat |
| T Ishikan. [Effects of serotonergic drugs on the up-regulation of dopamine D2 receptors induced by haloperidol in rat striatum]. [Hokkaido igaku zasshi] The Hokkaido journal of medical science. vol 73. issue 5. 1999-02-23. PMID:9846274. |
[effects of serotonergic drugs on the up-regulation of dopamine d2 receptors induced by haloperidol in rat striatum]. |
1999-02-23 |
2023-08-12 |
rat |
| T Ishikan. [Effects of serotonergic drugs on the up-regulation of dopamine D2 receptors induced by haloperidol in rat striatum]. [Hokkaido igaku zasshi] The Hokkaido journal of medical science. vol 73. issue 5. 1999-02-23. PMID:9846274. |
chronic treatment with haloperidol (0.1, 0.5 mg/kg, i.p., 3 weeks) increased the number of dopamine d2 receptors, while no increase was observed with atypical antipsychotic drugs clozapine (10 mg/kg) and org 5222 (0.25 mg/kg). |
1999-02-23 |
2023-08-12 |
rat |
| T Ishikan. [Effects of serotonergic drugs on the up-regulation of dopamine D2 receptors induced by haloperidol in rat striatum]. [Hokkaido igaku zasshi] The Hokkaido journal of medical science. vol 73. issue 5. 1999-02-23. PMID:9846274. |
chronic treatment with mk 212, a serotonin (5-ht)2a/2c receptor agonist (2.5 mg/kg), or with citalopram, a 5-ht reuptake inhibitor (10 mg/kg), potentiated the haloperidol (0.1 mg/kg)-induced up-regulation of dopamine d2 receptor, while that with (+/-)-8-hydroxy-2-(di-n-propylamino) tetralin (8-oh-dpat), a 5-ht1a receptor agonist (0.1 mg/kg), had no influence on the dopamine d2 receptor up-regulation. |
1999-02-23 |
2023-08-12 |
rat |
| T Ishikan. [Effects of serotonergic drugs on the up-regulation of dopamine D2 receptors induced by haloperidol in rat striatum]. [Hokkaido igaku zasshi] The Hokkaido journal of medical science. vol 73. issue 5. 1999-02-23. PMID:9846274. |
co-administration of ritanserin (1 mg/kg), a 5-ht2a/2c receptor antagonist, with a low dose of haloperidol (0.1 mg/kg), but not with a high dose of the agent (0.5 mg/kg), attenuated the dopamine d2 receptor up-regulation. |
1999-02-23 |
2023-08-12 |
rat |
| T Ishikan. [Effects of serotonergic drugs on the up-regulation of dopamine D2 receptors induced by haloperidol in rat striatum]. [Hokkaido igaku zasshi] The Hokkaido journal of medical science. vol 73. issue 5. 1999-02-23. PMID:9846274. |
drug occupation of 5-ht2a and dopamine d2 receptors in vivo examined with use of n-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline (eedq) was 69.8% and 45.1%, respectively, after the acute administration of haloperidol (0.1 mg/kg) plus ritanserin (1 mg/kg). |
1999-02-23 |
2023-08-12 |
rat |
| B A Chua, A M Perk. The effect of dopamine on lung liquid production by in vitro lungs from fetal guinea-pigs. The Journal of physiology. vol 513 ( Pt 1). 1999-01-29. PMID:9782178. |
dopamine at 10-6 m was tested together with each of three dopamine receptor antagonists at 10-5 m. the general dopamine receptor antagonist haloperidol and the more specific d2 receptor blocker domperidone both abolished responses, but the d1 receptor antagonist sch 23390 was without effect. |
1999-01-29 |
2023-08-12 |
Not clear |
| P A Broderick, M F Pierce. Clozapine, haloperidol, and the D4 antagonist PNU-101387G: in vivo effects on mesocortical, mesolimbic, and nigrostriatal dopamine and serotonin release. Journal of neural transmission (Vienna, Austria : 1996). vol 105. issue 6-7. 1999-01-26. PMID:9826116. |
clozapine, haloperidol, and the d4 antagonist pnu-101387g: in vivo effects on mesocortical, mesolimbic, and nigrostriatal dopamine and serotonin release. |
1999-01-26 |
2023-08-12 |
rat |
| P A Broderick, M F Pierce. Clozapine, haloperidol, and the D4 antagonist PNU-101387G: in vivo effects on mesocortical, mesolimbic, and nigrostriatal dopamine and serotonin release. Journal of neural transmission (Vienna, Austria : 1996). vol 105. issue 6-7. 1999-01-26. PMID:9826116. |
with in vivo microvoltammetry, the dopamine (da) receptor antagonists, clozapine (d4/d2), haloperidol (d2) and the selective d4 antagonist, pnu-101387g, were evaluated for their effects on da and serotonin (5-ht) release within a10 neuronal terminal fields [mesocortical, prefrontal cortex (pfc), mesolimbic, nucleus accumbens, (nacc)] and within a9 neuronal terminal fields [nigrostriatal, caudate putamen (cpu)], in chloral hydrate anesthetized rats. |
1999-01-26 |
2023-08-12 |
rat |
| T Hashimoto, Y Kajii, T Nishikaw. Psychotomimetic-induction of tissue plasminogen activator mRNA in corticostriatal neurons in rat brain. The European journal of neuroscience. vol 10. issue 11. 1999-01-14. PMID:9824452. |
moreover, map induction of tpa mrna was markedly inhibited by pretreatment with a d1 (r(+)-sch23390: r(+)-7-chloro-8-hydroxy-3-methyl-1-phenyl-2,3,4,5-tetra-hydro-1h-3-be nza zepine hydrochloride) or a d2 (haloperidol) dopamine receptor-preferring antagonist. |
1999-01-14 |
2023-08-12 |
rat |