| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| F X Vollenweider, M F Vollenweider-Scherpenhuyzen, A Bäbler, H Vogel, D Hel. Psilocybin induces schizophrenia-like psychosis in humans via a serotonin-2 agonist action. Neuroreport. vol 9. issue 17. 1999-03-24. PMID:9875725. |
in healthy human volunteers, the psychotomimetic effects of psilocybin were blocked dose-dependently by the serotonin-2a antagonist ketanserin or the atypical antipsychotic risperidone, but were increased by the dopamine antagonist and typical antipsychotic haloperidol. |
1999-03-24 |
2023-08-12 |
human |
| W R Wu, X Z Zh. The amphetamine-like reinforcing effect and mechanism of L-deprenyl on conditioned place preference in mice. European journal of pharmacology. vol 364. issue 1. 1999-03-22. PMID:9920178. |
pretreatment with the dopamine antagonist, haloperidol (1 mg/kg i.p. |
1999-03-22 |
2023-08-12 |
mouse |
| A M Gray, J H Connic. Clozapine-induced dopamine levels in the rat striatum and nucleus accumbens are not affected by muscarinic antagonism. European journal of pharmacology. vol 362. issue 2-3. 1999-03-18. PMID:9874162. |
the effect of the muscarinic antagonist, scopolamine, was examined for a change in the increase in extracellular dopamine, dihydroxyphenyl acetic acid (dopac), homovanillic acid (hva) and 5-hydroxyindolacetic acid (5-hiaa), induced by haloperidol or clozapine in the striatum and nucleus accumbens of anaesthetised and awake rats, monitored using in vivo cerebral microdialysis. |
1999-03-18 |
2023-08-12 |
rat |
| A Amer. Effects of the Aconitum alkaloid songorine on synaptic transmission and paired-pulse facilitation of CA1 pyramidal cells in rat hippocampal slices. British journal of pharmacology. vol 125. issue 3. 1999-03-04. PMID:9806328. |
however, the effect of songorine was completely abolished by the selective dopamine d2 receptor antagonist sulpiride (0.1 microm) as well as by haloperidol (10 microm) and was mimicked by application of the dopamine releaser, amantadine (100 mm). |
1999-03-04 |
2023-08-12 |
rat |
| B H Westerink, P de Boer, J B de Vries, C G Kruse, S K Lon. Antipsychotic drugs induce similar effects on the release of dopamine and noradrenaline in the medial prefrontal cortex of the rat brain. European journal of pharmacology. vol 361. issue 1. 1999-03-04. PMID:9851538. |
in the present study we have compared the effects of the classical antipsychotic drug haloperidol and four different atypical antipsychotics (clozapine, risperidone, olanzapine, ziprasidone) on extracellular levels of dopamine and noradrenaline in the medial prefrontal cortex (mpfc) of conscious rats. |
1999-03-04 |
2023-08-12 |
rat |
| R J Wyatt, F Karoum, J Masseran. Effects of antipsychotics, vitamin E, and MK-801 on dopamine dynamics in the rat brain following discontinuation of cocaine. Psychiatry research. vol 80. issue 3. 1999-02-25. PMID:9796937. |
in addition to the potential value these findings have for further understanding cocaine abuse, it is proposed that the alteration in dopamine metabolism produced by cocaine, and the ability of haloperidol, clozapine and vitamin e to decrease cocaine's effects, model some biochemical aspects of schizophrenia. |
1999-02-25 |
2023-08-12 |
rat |
| T Ishikan. [Effects of serotonergic drugs on the up-regulation of dopamine D2 receptors induced by haloperidol in rat striatum]. [Hokkaido igaku zasshi] The Hokkaido journal of medical science. vol 73. issue 5. 1999-02-23. PMID:9846274. |
[effects of serotonergic drugs on the up-regulation of dopamine d2 receptors induced by haloperidol in rat striatum]. |
1999-02-23 |
2023-08-12 |
rat |
| T Ishikan. [Effects of serotonergic drugs on the up-regulation of dopamine D2 receptors induced by haloperidol in rat striatum]. [Hokkaido igaku zasshi] The Hokkaido journal of medical science. vol 73. issue 5. 1999-02-23. PMID:9846274. |
chronic treatment with haloperidol (0.1, 0.5 mg/kg, i.p., 3 weeks) increased the number of dopamine d2 receptors, while no increase was observed with atypical antipsychotic drugs clozapine (10 mg/kg) and org 5222 (0.25 mg/kg). |
1999-02-23 |
2023-08-12 |
rat |
| T Ishikan. [Effects of serotonergic drugs on the up-regulation of dopamine D2 receptors induced by haloperidol in rat striatum]. [Hokkaido igaku zasshi] The Hokkaido journal of medical science. vol 73. issue 5. 1999-02-23. PMID:9846274. |
chronic treatment with mk 212, a serotonin (5-ht)2a/2c receptor agonist (2.5 mg/kg), or with citalopram, a 5-ht reuptake inhibitor (10 mg/kg), potentiated the haloperidol (0.1 mg/kg)-induced up-regulation of dopamine d2 receptor, while that with (+/-)-8-hydroxy-2-(di-n-propylamino) tetralin (8-oh-dpat), a 5-ht1a receptor agonist (0.1 mg/kg), had no influence on the dopamine d2 receptor up-regulation. |
1999-02-23 |
2023-08-12 |
rat |
| T Ishikan. [Effects of serotonergic drugs on the up-regulation of dopamine D2 receptors induced by haloperidol in rat striatum]. [Hokkaido igaku zasshi] The Hokkaido journal of medical science. vol 73. issue 5. 1999-02-23. PMID:9846274. |
co-administration of ritanserin (1 mg/kg), a 5-ht2a/2c receptor antagonist, with a low dose of haloperidol (0.1 mg/kg), but not with a high dose of the agent (0.5 mg/kg), attenuated the dopamine d2 receptor up-regulation. |
1999-02-23 |
2023-08-12 |
rat |
| T Ishikan. [Effects of serotonergic drugs on the up-regulation of dopamine D2 receptors induced by haloperidol in rat striatum]. [Hokkaido igaku zasshi] The Hokkaido journal of medical science. vol 73. issue 5. 1999-02-23. PMID:9846274. |
drug occupation of 5-ht2a and dopamine d2 receptors in vivo examined with use of n-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline (eedq) was 69.8% and 45.1%, respectively, after the acute administration of haloperidol (0.1 mg/kg) plus ritanserin (1 mg/kg). |
1999-02-23 |
2023-08-12 |
rat |
| B A Chua, A M Perk. The effect of dopamine on lung liquid production by in vitro lungs from fetal guinea-pigs. The Journal of physiology. vol 513 ( Pt 1). 1999-01-29. PMID:9782178. |
dopamine at 10-6 m was tested together with each of three dopamine receptor antagonists at 10-5 m. the general dopamine receptor antagonist haloperidol and the more specific d2 receptor blocker domperidone both abolished responses, but the d1 receptor antagonist sch 23390 was without effect. |
1999-01-29 |
2023-08-12 |
Not clear |
| P A Broderick, M F Pierce. Clozapine, haloperidol, and the D4 antagonist PNU-101387G: in vivo effects on mesocortical, mesolimbic, and nigrostriatal dopamine and serotonin release. Journal of neural transmission (Vienna, Austria : 1996). vol 105. issue 6-7. 1999-01-26. PMID:9826116. |
clozapine, haloperidol, and the d4 antagonist pnu-101387g: in vivo effects on mesocortical, mesolimbic, and nigrostriatal dopamine and serotonin release. |
1999-01-26 |
2023-08-12 |
rat |
| P A Broderick, M F Pierce. Clozapine, haloperidol, and the D4 antagonist PNU-101387G: in vivo effects on mesocortical, mesolimbic, and nigrostriatal dopamine and serotonin release. Journal of neural transmission (Vienna, Austria : 1996). vol 105. issue 6-7. 1999-01-26. PMID:9826116. |
with in vivo microvoltammetry, the dopamine (da) receptor antagonists, clozapine (d4/d2), haloperidol (d2) and the selective d4 antagonist, pnu-101387g, were evaluated for their effects on da and serotonin (5-ht) release within a10 neuronal terminal fields [mesocortical, prefrontal cortex (pfc), mesolimbic, nucleus accumbens, (nacc)] and within a9 neuronal terminal fields [nigrostriatal, caudate putamen (cpu)], in chloral hydrate anesthetized rats. |
1999-01-26 |
2023-08-12 |
rat |
| T Hashimoto, Y Kajii, T Nishikaw. Psychotomimetic-induction of tissue plasminogen activator mRNA in corticostriatal neurons in rat brain. The European journal of neuroscience. vol 10. issue 11. 1999-01-14. PMID:9824452. |
moreover, map induction of tpa mrna was markedly inhibited by pretreatment with a d1 (r(+)-sch23390: r(+)-7-chloro-8-hydroxy-3-methyl-1-phenyl-2,3,4,5-tetra-hydro-1h-3-be nza zepine hydrochloride) or a d2 (haloperidol) dopamine receptor-preferring antagonist. |
1999-01-14 |
2023-08-12 |
rat |
| G K Mulholland, D M Wieland, M R Kilbourn, K A Frey, P S Sherman, J E Carey, D E Kuh. [18F]fluoroethoxy-benzovesamicol, a PET radiotracer for the vesicular acetylcholine transporter and cholinergic synapses. Synapse (New York, N.Y.). vol 30. issue 3. 1998-12-28. PMID:9776130. |
(-)-[18f]feobv regional brain distribution in rodents was changed little by pretreatment with haloperidol, (+)-3-ppp, or e-2020, indicating feobv, unlike other vesamicol analogs, did not interact in vivo with dopamine or sigma receptor systems. |
1998-12-28 |
2023-08-12 |
mouse |
| D S Zahm, E S Williams, J E Krause, M A Welch, D S Gros. Distinct and interactive effects of d-amphetamine and haloperidol on levels of neurotensin and its mRNA in subterritories in the dorsal and ventral striatum of the rat. The Journal of comparative neurology. vol 400. issue 4. 1998-12-23. PMID:9786410. |
striatal tissue concentrations of neurotensin, expression of neurotensin/neuromedin n (nt/n) mrna, and numbers of neurotensin-immunoreactive neurons are increased by d-amphetamine (amph), which stimulates dopamine release in the striatum, and haloperidol (hal), a dopamine receptor antagonist with high affinity for d2-like receptors. |
1998-12-23 |
2023-08-12 |
rat |
| R R Holson, R A Gazzara, B Goug. Declines in stimulated striatal dopamine release over the first 32 h following microdialysis probe insertion: generalization across releasing mechanisms. Brain research. vol 808. issue 2. 1998-12-11. PMID:9767162. |
injection of 0.5 mg/kg haloperidol released three times as much dopamine when given two compared to six hours post-implantation. |
1998-12-11 |
2023-08-12 |
rat |
| V Audinot, A Newman-Tancredi, A Gobert, J M Rivet, M Brocco, F Lejeune, L Gluck, I Desposte, K Bervoets, A Dekeyne, M J Milla. A comparative in vitro and in vivo pharmacological characterization of the novel dopamine D3 receptor antagonists (+)-S 14297, nafadotride, GR 103,691 and U 99194. The Journal of pharmacology and experimental therapeutics. vol 287. issue 1. 1998-11-05. PMID:9765337. |
haloperidol, (+)-aj 76, (+)-uh 232, nafadotride and (weakly) u 99194 also enhanced prolactin secretion and striatal dopamine synthesis, whereas (+)-s 14297 and gr 103,691 were inactive. |
1998-11-05 |
2023-08-12 |
human |
| A Umino, K Takahashi, T Nishikaw. Characterization of the phencyclidine-induced increase in prefrontal cortical dopamine metabolism in the rat. British journal of pharmacology. vol 124. issue 2. 1998-10-29. PMID:9641556. |
the increasing effects of pcp and selective nmda antagonists on cortical dopamine utilization were not additive, although a dopamine receptor antagonist, haloperidol, still accelerated the disappearance of dopamine, even in the presence of pcp. |
1998-10-29 |
2023-08-12 |
rat |