| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Y Minabe, E L Gardner, C R Ashb. Differential effects of chronic haloperidol administration on midbrain dopamine neurons in Sprague-Dawley, Fischer 344, and Lewis rats: an in vivo electrophysiological study. Synapse (New York, N.Y.). vol 29. issue 3. 1998-08-20. PMID:9635897. |
differential effects of chronic haloperidol administration on midbrain dopamine neurons in sprague-dawley, fischer 344, and lewis rats: an in vivo electrophysiological study. |
1998-08-20 |
2023-08-12 |
rat |
| S Monleón, C Vinader-Caerols, A Parr. Sex differences in escape-avoidance response in mice after acute administration of raclopride, clozapine, and SCH 23390. Pharmacology, biochemistry, and behavior. vol 60. issue 2. 1998-08-17. PMID:9632232. |
it is concluded that, besides haloperidol, other dopamine antagonists also show sex differences in their behavioral effects in escape-avoidance response in mice, with males being more affected than females by the inhibitory action of these drugs. |
1998-08-17 |
2023-08-12 |
mouse |
| S Dresel, K Tatsch, I Dähne, T Mager, J Scherer, K Hah. Iodine-123-iodobenzamide SPECT assessment of dopamine D2 receptor occupancy in riperidone-treated schizophrenic patients. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. vol 39. issue 7. 1998-08-11. PMID:9669383. |
the recently introduced neuroleptic, risperidone, was expected to block fewer dopamine d2 receptors than typical neuroleptics (e.g., haloperidol), but at comparable potency. |
1998-08-11 |
2023-08-12 |
Not clear |
| S Kasper, J Tauscher, B Küfferle, C Barnas, B Hesselmann, S Asenbaum, I Podreka, T Brück. Sertindole and dopamine D2 receptor occupancy in comparison to risperidone, clozapine and haloperidol - a 123I-IBZM SPECT study. Psychopharmacology. vol 136. issue 4. 1998-08-07. PMID:9600582. |
sertindole and dopamine d2 receptor occupancy in comparison to risperidone, clozapine and haloperidol - a 123i-ibzm spect study. |
1998-08-07 |
2023-08-12 |
Not clear |
| E R Bongarzone, S G Howard, V Schonmann, A T Campagnon. Identification of the dopamine D3 receptor in oligodendrocyte precursors: potential role in regulating differentiation and myelin formation. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 18. issue 14. 1998-07-27. PMID:9651217. |
this effect was prevented by the dopamine antagonist haloperidol. |
1998-07-27 |
2023-08-12 |
Not clear |
| A M Wright, J Bempong, M L Kirby, R L Barlow, J R Bloomquis. Effects of haloperidol metabolites on neurotransmitter uptake and release: possible role in neurotoxicity and tardive dyskinesia. Brain research. vol 788. issue 1-2. 1998-07-23. PMID:9555021. |
in synaptosome preparations from mouse striatum and cortex, the hp metabolites haloperidol pyridinium (hpp+), reduced haloperidol pyridinium (rhpp+), and haloperidol tetrahydropyridine (hptp) inhibited the presynaptic uptake of dopamine and serotonin, with greater affinity for the serotonin transporter. |
1998-07-23 |
2023-08-12 |
mouse |
| R Y Wang, X Lian. M100907 and clozapine, but not haloperidol or raclopride, prevent phencyclidine-induced blockade of NMDA responses in pyramidal neurons of the rat medial prefrontal cortical slice. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 19. issue 1. 1998-07-20. PMID:9608579. |
furthermore, the atypical apd clozapine, but not the typical apd haloperidol or raclopride (a selective dopamine d2,3 receptor antagonist), mimicked the action of m100907, preventing the pcp-induced effect. |
1998-07-20 |
2023-08-12 |
rat |
| L Ouedraogo, M Magnon, L Sawadogo, R Tricoch. Receptors involved in the positive inotropic action induced by dopamine on the ventricle of a 7-day-old chick embryo heart. Fundamental & clinical pharmacology. vol 12. issue 2. 1998-07-16. PMID:9565766. |
moreover, haloperidol (2 microm) antagonized the positive inotropic response to dopamine but had not any significant effect on the response to isoprenaline. |
1998-07-16 |
2023-08-12 |
chicken |
| L Ouedraogo, M Magnon, L Sawadogo, R Tricoch. Receptors involved in the positive inotropic action induced by dopamine on the ventricle of a 7-day-old chick embryo heart. Fundamental & clinical pharmacology. vol 12. issue 2. 1998-07-16. PMID:9565766. |
the combined application of both propranolol and haloperidol antagonized the positive inotropic response to dopamine to a greater extent than when these two antagonists were given alone. |
1998-07-16 |
2023-08-12 |
chicken |
| L Ouedraogo, M Magnon, L Sawadogo, R Tricoch. Receptors involved in the positive inotropic action induced by dopamine on the ventricle of a 7-day-old chick embryo heart. Fundamental & clinical pharmacology. vol 12. issue 2. 1998-07-16. PMID:9565766. |
furthermore, in preparations in which sodium channels were inactivated by high potassium physiological salt solution, high concentrations of dopamine (0.1 mm to 1 mm) induced a slow developing electrical and positive inotropic responses which were also inhibited by propranolol and haloperidol, but not by phentolamine. |
1998-07-16 |
2023-08-12 |
chicken |
| P Seeman, T Talleric. Antipsychotic drugs which elicit little or no parkinsonism bind more loosely than dopamine to brain D2 receptors, yet occupy high levels of these receptors. Molecular psychiatry. vol 3. issue 2. 1998-07-16. PMID:9577836. |
as determined by the new dissociation constants, antipsychotic drugs which elicit parkinsonism (trifluperazine, chlorpromazine, raclopride, haloperidol, fluphenazine, risperidone) bind more tightly than dopamine to d2, while those antipsychotic drugs which elicit little or no parkinsonism (melperone, seroquel, perlapine, clozapine, remoxipride, molindone, sulpiride, olanzapine, sertindole) bind more loosely than dopamine to d2 receptors. |
1998-07-16 |
2023-08-12 |
human |
| B K Yamamoto, S Novotne. Regulation of extracellular dopamine by the norepinephrine transporter. Journal of neurochemistry. vol 71. issue 1. 1998-07-09. PMID:9648875. |
the combined systemic administration of haloperidol and the local infusion of dmi produced an augmented increase in extracellular dopamine in the cortex compared with the increase produced by either drug alone. |
1998-07-09 |
2023-08-12 |
rat |
| B K Yamamoto, S Novotne. Regulation of extracellular dopamine by the norepinephrine transporter. Journal of neurochemistry. vol 71. issue 1. 1998-07-09. PMID:9648875. |
this synergistic increase in dopamine overflow is likely due to the combination of impulse-mediated dopamine release produced by haloperidol and blockade of the norepinephrine transporter. |
1998-07-09 |
2023-08-12 |
rat |
| B K Yamamoto, S Novotne. Regulation of extracellular dopamine by the norepinephrine transporter. Journal of neurochemistry. vol 71. issue 1. 1998-07-09. PMID:9648875. |
although the stimulation of extracellular dopamine by idazoxan and dmi could be due to the increased extracellular concentrations of norepinephrine produced by these drugs, an increase in dopamine also was observed in lesioned rats that were depleted of norepinephrine and challenged with haloperidol. |
1998-07-09 |
2023-08-12 |
rat |
| B K Yamamoto, S Novotne. Regulation of extracellular dopamine by the norepinephrine transporter. Journal of neurochemistry. vol 71. issue 1. 1998-07-09. PMID:9648875. |
this contrasted with the lack of an effect of haloperidol on cortical dopamine in unlesioned controls. |
1998-07-09 |
2023-08-12 |
rat |
| G Davidkova, L W Zhou, M Morabito, S P Zhang, B Weis. D2 dopamine antisense RNA expression vector, unlike haloperidol, produces long-term inhibition of D2 dopamine-mediated behaviors without causing Up-regulation of D2 dopamine receptors. The Journal of pharmacology and experimental therapeutics. vol 285. issue 3. 1998-07-02. PMID:9618422. |
d2 dopamine antisense rna expression vector, unlike haloperidol, produces long-term inhibition of d2 dopamine-mediated behaviors without causing up-regulation of d2 dopamine receptors. |
1998-07-02 |
2023-08-12 |
mouse |
| G Davidkova, L W Zhou, M Morabito, S P Zhang, B Weis. D2 dopamine antisense RNA expression vector, unlike haloperidol, produces long-term inhibition of D2 dopamine-mediated behaviors without causing Up-regulation of D2 dopamine receptors. The Journal of pharmacology and experimental therapeutics. vol 285. issue 3. 1998-07-02. PMID:9618422. |
long-term inhibition of d2 dopamine receptors using classic d2 dopamine receptor antagonists such as haloperidol often causes a compensatory up-regulation of the d2 dopamine receptors. |
1998-07-02 |
2023-08-12 |
mouse |
| H Moore, C L Todd, A A Grac. Striatal extracellular dopamine levels in rats with haloperidol-induced depolarization block of substantia nigra dopamine neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 18. issue 13. 1998-07-02. PMID:9634572. |
correlations between substantia nigra (sn) dopamine (da) cell activity and striatal extracellular da were examined using simultaneous extracellular single-unit recordings and in vivo microdialysis performed in drug-naive rats and in rats treated repeatedly with haloperidol (hal). |
1998-07-02 |
2023-08-12 |
rat |
| T Ozaki, E Katsumoto, K Mui, D Furutsuka, S Yamagam. Distribution of Fos- and Jun-related proteins and activator protein-1 composite factors in mouse brain induced by neuroleptics. Neuroscience. vol 84. issue 4. 1998-06-23. PMID:9578405. |
we immunocytochemically investigated the expression of fos- and jun-related proteins and examined activator protein-1 dna-binding activity in ddy mouse brain 120 min after the administration of haloperidol (1 mg/kg), (-)-sulpiride (20 mg/kg) and a selective dopamine d1 receptor antagonist, sch23390 (1 mg/kg). |
1998-06-23 |
2023-08-12 |
mouse |
| K E Vanove. Effects of AMPA receptor antagonists on dopamine-mediated behaviors in mice. Psychopharmacology. vol 136. issue 2. 1998-06-18. PMID:9551768. |
the noncompetitive ampa antagonists, gyki 52466 (5-40 mg/kg) and ly300164 (1-6 mg/kg), and the competitive ampa antagonists, ly326325 (5-80 mg/kg) and nbqx (10-80 mg/kg), were compared to the dopamine antagonist, haloperidol (0.03-1.0 mg/kg), for their ability to inhibit dopamine-mediated behaviors after i.p. |
1998-06-18 |
2023-08-12 |
mouse |