| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| W Huang, G R Hanso. Differential effect of haloperidol on release of neurotensin in extrapyramidal and limbic systems. European journal of pharmacology. vol 332. issue 1. 1997-10-30. PMID:9298921. |
the effect of the antipsychotic drug haloperidol on extracellular neurotensin-like immunoreactivity was investigated by microdialysis and compared with the time-dependent response of tissue neurotensin-like immunoreactivity content in brain structures containing dopamine nerve cell bodies and terminals. |
1997-10-30 |
2023-08-12 |
Not clear |
| W Huang, G R Hanso. Differential effect of haloperidol on release of neurotensin in extrapyramidal and limbic systems. European journal of pharmacology. vol 332. issue 1. 1997-10-30. PMID:9298921. |
these findings suggest that varied neurotensin systems are associated with nigrostriatal and mesolimbic dopamine pathways and these systems have different responses to haloperidol. |
1997-10-30 |
2023-08-12 |
Not clear |
| W Huang, G R Hanso. Differential effect of haloperidol on release of neurotensin in extrapyramidal and limbic systems. European journal of pharmacology. vol 332. issue 1. 1997-10-30. PMID:9298921. |
differential actions of haloperidol on neurotensin release might be due to regional differences in dopamine or sigma receptor subtypes associated with the neurotensin-containing neurons. |
1997-10-30 |
2023-08-12 |
Not clear |
| B D Kretschmer, U Kratzer, K Breithecker, M Koc. ACEA 1021, a glycine site antagonist with minor psychotomimetic and amnestic effects in rats. European journal of pharmacology. vol 331. issue 2-3. 1997-10-27. PMID:9274968. |
anti-cataleptic properties of acea 1021 in dopamine d2 (haloperidol (4'fluoro-4-(1-(4-hydroxy-4-p-chlorophenyl-piperidino)-butyrophe non)) or d1 (sch 23390 (7-chloro-8-hydroxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1h-3-benzaze pin e hydrochloride)) receptor antagonist-pretreated rats were only minor. |
1997-10-27 |
2023-08-12 |
rat |
| S O Ogren, S Ferré, R Schwarcz, K Fux. Prolonged treatment with haloperidol and clozapine in the rat: differential effects on spontaneous and theophylline-induced motor activity. Neuroscience letters. vol 232. issue 1. 1997-10-23. PMID:9292882. |
difference in striatal dopamine d2 receptors and in spontaneous and theophylline-induced motor activity in rats withdrawn (for 72 h) from prolonged treatment with haloperidol or clozapine were studied. |
1997-10-23 |
2023-08-12 |
rat |
| S O Ogren, S Ferré, R Schwarcz, K Fux. Prolonged treatment with haloperidol and clozapine in the rat: differential effects on spontaneous and theophylline-induced motor activity. Neuroscience letters. vol 232. issue 1. 1997-10-23. PMID:9292882. |
haloperidol but not clozapine pretreatment increased the binding of the dopamine d2 antagonist [3h]raclopride in striatal membrane preparations, due to an increased number of striatal dopamine d2 receptors (bmax) without changes in affinity (kd). |
1997-10-23 |
2023-08-12 |
rat |
| M S Reid, K Hsu, S P Berge. Cocaine and amphetamine preferentially stimulate glutamate release in the limbic system: studies on the involvement of dopamine. Synapse (New York, N.Y.). vol 27. issue 2. 1997-10-21. PMID:9266771. |
the increase in nucleus accumbens glutamate levels following cocaine (30 mg/kg) was calcium-dependent and was blocked by pretreatment with dopamine antagonists; haloperidol (0.2 mg/kg, i.p. |
1997-10-21 |
2023-08-12 |
rat |
| Y Ohno, K Ishida-Tokuda, T Ishibashi, M Nakamur. Effects of perospirone (SM-9018), a potential atypical neuroleptic, on dopamine D1 receptor-mediated vacuous chewing movement in rats: a role of 5-HT2 receptor blocking activity. Pharmacology, biochemistry, and behavior. vol 57. issue 4. 1997-10-16. PMID:9259021. |
we compared the acute and subacute effects of perospirone (sm-9018), a novel neuroleptic with potent 5-ht2 and d2 blocking actions, and of haloperidol (hal) on dopamine d1 receptor-mediated vacuous chewing movement (vcm) in rats. |
1997-10-16 |
2023-08-12 |
rat |
| Y P Tang, Y Noda, T Nabeshim. Involvement of activation of dopaminergic neuronal system in learning and memory deficits associated with experimental mild traumatic brain injury. The European journal of neuroscience. vol 9. issue 8. 1997-10-16. PMID:9283826. |
administration of haloperidol but not of apomorphine significantly shortened the prolonged latency in both of the tests, indicating that antagonism of dopamine receptors is beneficial for the recovery of post traumatic memory deficits. |
1997-10-16 |
2023-08-12 |
mouse |
| H Basson, A Bairam, J M Cottet-Emard, J M Pequignot, F Marcha. Carotid body dopamine content and release by short-term hypoxia: effect of haloperidol and alpha methyl paratyrosine. Archives of physiology and biochemistry. vol 105. issue 1. 1997-10-09. PMID:9224540. |
carotid body dopamine content and release by short-term hypoxia: effect of haloperidol and alpha methyl paratyrosine. |
1997-10-09 |
2023-08-12 |
Not clear |
| I Ushijima, M Kawano, H Kaneyuki, M Suetsugi, K Usami, H Hirano, Y Mizuki, M Yamad. Dopaminergic and cholinergic interaction in cataleptic responses in mice. Pharmacology, biochemistry, and behavior. vol 58. issue 1. 1997-09-30. PMID:9264077. |
the cataleptogenic effects of haloperidol, a dopamine d2 receptor antagonist; sch23390, a d1 receptor antagonist; physostigmine, a cholinesterase inhibitor; and pilocarpine, a muscarinic m1 receptor agonist, were challenged by pretreatment of mice with skf38393, a dopamine d1 receptor agonist; apomorphine, a dopamine d1/d2 receptor agonist (mainly d2 receptor); pirenzepine, a muscarinic m1 receptor antagonist; and scopolamine, a muscarinic m1/m2 receptor antagonist. |
1997-09-30 |
2023-08-12 |
mouse |
| J N DaSilva, J E Carey, P S Sherman, T J Pisani, M R Kilbour. Characterization of [11C]tetrabenazine as an in vivo radioligand for the vesicular monoamine transporter. Nuclear medicine and biology. vol 21. issue 2. 1997-09-25. PMID:9234277. |
regional mouse brain retention of [11c]tbz is highest in brain regions with greatest monoaminergic innervation (striatum, hypothalamus) and can be reduced with ligands for the monoamine vesicular transporter (tbz, ketanserin) but not haloperidol, a dopamine d2 receptor antagonist. |
1997-09-25 |
2023-08-12 |
mouse |
| A Newman-Tancredi, V Audinot-Bouchez, A Gobert, M J Milla. Noradrenaline and adrenaline are high affinity agonists at dopamine D4 receptors. European journal of pharmacology. vol 319. issue 2-3. 1997-09-22. PMID:9042615. |
the dopamine d4 receptor-selective ligand, 3-(4-[4-chlorophenyl]piperazin-1-yl)methyl-1h-pyrrolo[2,3b]-pyridi ne (l 745,870) and the dopaminergic antagonists, spiperone, haloperidol and clozapine, inhibited noradrenaline-stimulated [35s]gtp gamma s binding whereas alpha 1-, alpha 2- and beta-adrenoceptor antagonists did not. |
1997-09-22 |
2023-08-12 |
Not clear |
| G D Tollefson, C M Beasley, R N Tamura, P V Tran, J H Potvi. Blind, controlled, long-term study of the comparative incidence of treatment-emergent tardive dyskinesia with olanzapine or haloperidol. The American journal of psychiatry. vol 154. issue 9. 1997-09-18. PMID:9286184. |
the authors' goal was to compare the incidence of tardive dyskinesia among patients receiving olanzapine and those receiving the conventional dopamine 2 antagonist haloperidol. |
1997-09-18 |
2023-08-12 |
Not clear |
| Z Grabarević, I Rotkvić, P Sikirić, S Seiwerth, P Dzaja, J Perić, J Ko. Brain-mediated protective interactions of histaminergic H2 and dopaminergic systems in rats. Acta veterinaria Hungarica. vol 45. issue 1. 1997-09-15. PMID:9270132. |
on the other hand, pretreatment with dopamine antagonists (haloperidol 5.0, sulpiride 1.0, domperidone 5.0 mg/kg i.p.) |
1997-09-15 |
2023-08-12 |
rat |
| Z Grabarević, I Rotkvić, P Sikirić, S Seiwerth, P Dzaja, J Perić, J Ko. Brain-mediated protective interactions of histaminergic H2 and dopaminergic systems in rats. Acta veterinaria Hungarica. vol 45. issue 1. 1997-09-15. PMID:9270132. |
cimetidine markedly diminished the ulcerogenic effect of haloperidol but not that of domperidone, suggesting a brain-mediated site for the protective interaction of cimetidine and dopamine systems. |
1997-09-15 |
2023-08-12 |
rat |
| A C Franco, W A Prad. Antinociceptive effects of stimulation of discrete sites in the rat hypothalamus: evidence for the participation of the lateral hypothalamus area in descending pain suppression mechanisms. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 29. issue 11. 1997-09-11. PMID:9196558. |
the effects of intraperitoneal administration of antagonists to opioids (naloxone), 5-hydroxytryptamine (methysergide), noradrenaline (phenoxybenzamine), dopamine (haloperidol), and acetylcholine (atropine and mecamylamine) on the antinociceptive effects of lha stimulation were also examined. |
1997-09-11 |
2023-08-12 |
rat |
| M R Adams, D J Dobie, K M Merchant, A Unis, D M Dors. EEDQ reduces the striatal neurotensin mRNA response to haloperidol. Peptides. vol 18. issue 4. 1997-09-11. PMID:9210171. |
haloperidol is believed to induce neurotensin/neuromedin n (nt/ n) gene expression in the dorsolateral striatum (dlst) of the rat brain via dopamine d2 receptor blockade, but is also known to interact with other receptors as well. |
1997-09-11 |
2023-08-12 |
rat |
| S Kapur, R Zipursky, P Roy, C Jones, G Remington, K Reed, S Houl. The relationship between D2 receptor occupancy and plasma levels on low dose oral haloperidol: a PET study. Psychopharmacology. vol 131. issue 2. 1997-09-05. PMID:9201802. |
the purpose of this study was to determine the relationship between dopamine d2 receptor occupancy and plasma haloperidol. |
1997-09-05 |
2023-08-12 |
Not clear |
| S Kapur, R Zipursky, P Roy, C Jones, G Remington, K Reed, S Houl. The relationship between D2 receptor occupancy and plasma levels on low dose oral haloperidol: a PET study. Psychopharmacology. vol 131. issue 2. 1997-09-05. PMID:9201802. |
our findings demonstrate that 2-5 mg/day of haloperidol, which usually leads to plasma levels of 1-2 ng/ml, would be expected to induce 60-80% dopamine d2 receptor occupancy. |
1997-09-05 |
2023-08-12 |
Not clear |