| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C J Van der Schyf, I C Dormehl, D W Oliver, N Hugo, R Keeve, H W Müller-Gärtner, S M Pond, N Castagnol. Long-term treatment with the tetrahydropyridine analog (HPTP) of haloperidol influences dopamine ligand binding in baboon brain. An [123I]iodobenzamide (IBZM) SPECT study. Brain research. Molecular brain research. vol 43. issue 1-2. 1997-05-29. PMID:9037540. |
long-term treatment with the tetrahydropyridine analog (hptp) of haloperidol influences dopamine ligand binding in baboon brain. |
1997-05-29 |
2023-08-12 |
Not clear |
| T A Jenkins, S Y Chai, F A Mendelsoh. Upregulation of angiotensin II AT1 receptors in the mouse nucleus accumbens by chronic haloperidol treatment. Brain research. vol 748. issue 1-2. 1997-05-27. PMID:9067454. |
considering our previous anatomical and functional studies demonstrating an interaction between brain angiotensin ii and dopaminergic systems, the effect of chronic treatment with the dopamine antagonist, haloperidol, on at1 and at2 receptor levels was investigated in the mouse brain. |
1997-05-27 |
2023-08-12 |
mouse |
| T A Jenkins, S Y Chai, F A Mendelsoh. Upregulation of angiotensin II AT1 receptors in the mouse nucleus accumbens by chronic haloperidol treatment. Brain research. vol 748. issue 1-2. 1997-05-27. PMID:9067454. |
haloperidol treatment for 21 days resulted in an increase in angiotensin ii at1 receptor levels in the nucleus accumbens, accompanied by an increase in dopamine d2 receptors, but no change in dopamine d1 receptors. |
1997-05-27 |
2023-08-12 |
mouse |
| C Pellevoisin, D Guilloteau, J L Baulieu, C Loc'h, A M Dognon, L Mauclaire, J C Saccavini, J C Besnard, S Chalo. Iodolisuride and iodobenzamide, two ligands for SPECT exploration of the dopaminergic D2 receptors: a comparative study. Synapse (New York, N.Y.). vol 24. issue 1. 1997-05-22. PMID:9046079. |
ibzm and ilis have a similar cerebral distribution in vivo in control rats and permitted the detection of upregulation of striatal dopamine d2 receptors in a model of chronic haloperidol treatment. |
1997-05-22 |
2023-08-12 |
human |
| B P Meij, J A Mol, T S van den Ingh, M M Bevers, H A Hazewinkel, A Rijnber. Assessment of pituitary function after transsphenoidal hypophysectomy in beagle dogs. Domestic animal endocrinology. vol 14. issue 2. 1997-05-15. PMID:9063651. |
pars intermedia function was assessed by the alpha-melanotropin (alpha-msh) response to the intravenous injection of the dopamine antagonist haloperidol in a dosage of 0.2 mg/kg. |
1997-05-15 |
2023-08-12 |
Not clear |
| J S Schneide. Preservation of autoreceptor-mediated increases in dopamine synthesis in aged mice with experimentally-induced parkinsonism. Neuroscience letters. vol 222. issue 2. 1997-05-12. PMID:9111748. |
this study examined autoreceptor (i.e haloperidol)-mediated regulation of dopamine synthesis in normal aged mice and aged mice with a partial lesion of the nigrostriatal dopamine system induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp). |
1997-05-12 |
2023-08-12 |
mouse |
| J Fan. Hyperactive behavioural effects induced by intranigral infusion of a pyridinium metabolite of haloperidol in rats. Canadian journal of physiology and pharmacology. vol 74. issue 12. 1997-05-08. PMID:9047047. |
this apparent dopamine agonist effect of hp+ may be relevant to some of the clinical side effects of haloperidol such as acute dystonia and chronic tardive dyskinesia, which have been proposed to be the result of dopaminergic hyperactivity. |
1997-05-08 |
2023-08-12 |
rat |
| T Sumiyoshi, J Ichikawa, H Y Meltze. The effect of streptozotocin-induced diabetes on dopamine2, serotonin1A and serotonin2A receptors in the rat brain. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 16. issue 3. 1997-05-08. PMID:9138434. |
the effect of streptozotocin (stz)-induced diabetes and a combination of chronic treatment with haloperidol (hpd) on dopamine (da)d2, serotonin (5-ht) 5-ht1a and 5-ht2a receptors was investigated in rat brain. |
1997-05-08 |
2023-08-12 |
rat |
| C L Nilsson, A Ekman, M Hellstrand, E Eriksso. Inverse agonism at dopamine D2 receptors. Haloperidol-induced prolactin release from GH4C1 cells transfected with the human D2 receptor is antagonized by R(-)-n-propylnorapomorphine, raclopride, and phenoxybenzamine. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 15. issue 1. 1997-05-02. PMID:8797192. |
our earlier observation that the antipsychotic drug haloperidol in the absence of dopamine increases camp formation and prolactin release in two prolactin-producing cell lines expressing rat dopamine d2 receptors (gh3, gh4zr7), but not in similar cells devoid of d2 receptors (gh4c1), prompted us to suggest that haloperidol may act as an inverse (or negative) agonist, rather than as a neutral antagonist, at the d2 receptor (nilsson and eriksson 1993). |
1997-05-02 |
2023-08-12 |
human |
| C L Nilsson, A Ekman, M Hellstrand, E Eriksso. Inverse agonism at dopamine D2 receptors. Haloperidol-induced prolactin release from GH4C1 cells transfected with the human D2 receptor is antagonized by R(-)-n-propylnorapomorphine, raclopride, and phenoxybenzamine. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 15. issue 1. 1997-05-02. PMID:8797192. |
in the present study it is shown that haloperidol elicits a dose-dependent increase in prolactin release also in prolactin-producing gh4c1 cells transfected with the human dopamine d2 receptor (short isoform) (gh4c1-hd2s); in addition, it is shown that another antipsychotic drug, flupenthixol, also causes prolactin release per se in this cell line. |
1997-05-02 |
2023-08-12 |
human |
| M Beuger, D P van Kammen, M E Kelley, J Ya. Dopamine turnover in schizophrenia before and after haloperidol withdrawal. CSF, plasma, and urine studies. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 15. issue 1. 1997-05-02. PMID:8797194. |
dopamine turnover in schizophrenia before and after haloperidol withdrawal. |
1997-05-02 |
2023-08-12 |
Not clear |
| M Beuger, D P van Kammen, M E Kelley, J Ya. Dopamine turnover in schizophrenia before and after haloperidol withdrawal. CSF, plasma, and urine studies. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 15. issue 1. 1997-05-02. PMID:8797194. |
we conclude that haloperidol withdrawal had a strong effect on dopamine turnover, whereas the patient's clinical state had only a weak central effect, without affecting total body production of hva. |
1997-05-02 |
2023-08-12 |
Not clear |
| B Küfferle, T Brücke, A Topitz-Schratzberger, J Tauscher, R Gössler, C Vesely, S Asenbaum, I Podreka, S Kaspe. Striatal dopamine-2 receptor occupancy in psychotic patients treated with risperidone. Psychiatry research. vol 68. issue 1. 1997-04-30. PMID:9027930. |
a statistically significant difference was also found concerning these ratios and percentage of dopamine d2 receptor occupancy rates between the treatment groups with lowest ratios and highest percentage of d2 receptor occupancy in the group of patients treated with haloperidol, followed by the group treated with 8 mg of risperidone and the group treated with 3 mg of risperidone. |
1997-04-30 |
2023-08-12 |
human |
| S K Hore, V K Dumka, D Kumar, H C Tripathi, S K Tanda. Central noradrenergic & dopaminergic modulation of brewer's yeast-induced inflammation & nociception in rats. The Indian journal of medical research. vol 105. 1997-04-29. PMID:9055502. |
conversely, the beta-adrenoceptor blocker, propranolol, catecholaminergic neuron degenerator, 6-hydroxydopamine (6-ohda), dopaminergic antagonist, haloperidol and dopamine synthesis inhibitor, alpha-methyl para tyrosine (ampt) augmented paw oedema. |
1997-04-29 |
2023-08-12 |
rat |
| G Palacios, M A Muro, A Paz Marí. Differential effects of haloperidol and two anxiolytic drugs, buspirone and lesopitron, on c-Fos expression in the rat striatum and nucleus accumbens. Brain research. vol 742. issue 1-2. 1997-04-22. PMID:9117387. |
the induction of c-fos immunoreactivity by buspirone is compatible with an interaction of this compound with d2 dopamine receptors, as documented for haloperidol. |
1997-04-22 |
2023-08-12 |
rat |
| P Khosla, S Kothari, M C Gupt. Effect of haloperidol, a dopamine antagonist on aqueous humour dynamics in experimental glaucoma. Indian journal of experimental biology. vol 34. issue 11. 1997-04-17. PMID:9055635. |
effect of haloperidol, a dopamine antagonist on aqueous humour dynamics in experimental glaucoma. |
1997-04-17 |
2023-08-12 |
Not clear |
| F I Tarazi, W J Florijn, I Crees. Regulation of ionotropic glutamate receptors following subchronic and chronic treatment with typical and atypical antipsychotics. Psychopharmacology. vol 128. issue 4. 1997-04-16. PMID:8986008. |
quantitative in vitro receptor autoradiography was used to examine changes in three ionotropic glutamate receptor subtypes using 3h-mk801 (nmda-r antagonist), 3h-cnqx (ampa-r antagonist) and 3h-kainic acid (kainate-r agonist) following subchronic (28 days) and chronic (8 months) treatment of rats with a typical antipsychotic, haloperidol (1.5 mg/kg per day), atypical antipsychotic, clozapine (25 mg/kg per day), the dopamine d2/d3 receptor antagonist, raclopride (10 mg/kg per day), and the dopamine d1 (d1/d5) receptor antagonist sch23390 (0.5 mg/kg per day). |
1997-04-16 |
2023-08-12 |
rat |
| G D Tollefson, C M Beasley, P V Tran, J S Street, J A Krueger, R N Tamura, K A Graffeo, M E Thiem. Olanzapine versus haloperidol in the treatment of schizophrenia and schizoaffective and schizophreniform disorders: results of an international collaborative trial. The American journal of psychiatry. vol 154. issue 4. 1997-04-16. PMID:9090331. |
this international, multicenter double-blind trial was designed to compare the therapeutic profile of an atypical antipsychotic, olanzapine, with that of a conventional dopamine d2 antagonist, haloperidol. |
1997-04-16 |
2023-08-12 |
Not clear |
| E P Prinssen, M S Kleven, W Koe. Effects of dopamine antagonists in a two-way active avoidance procedure in rats: interactions with 8-OH-DPAT, ritanserin, and prazosin. Psychopharmacology. vol 128. issue 2. 1997-04-10. PMID:8956380. |
using a conditioned avoidance procedure in rats, the present study examined the ability of 8-oh-dpat, ritanserin, and prazosin to alter the effects of the dopamine antagonists, raclopride and haloperidol, on avoidance- and on escape responding. |
1997-04-10 |
2023-08-12 |
rat |
| E P Prinssen, M S Kleven, W Koe. Effects of dopamine antagonists in a two-way active avoidance procedure in rats: interactions with 8-OH-DPAT, ritanserin, and prazosin. Psychopharmacology. vol 128. issue 2. 1997-04-10. PMID:8956380. |
the alpha 1-adrenoceptor antagonist prazosin (0.63 mg/kg) significantly enhanced the effects of raclopride on the conditioned avoidance response, but enhanced the effects of only a single dose of haloperidol; prazosin did not alter the effects of either dopamine antagonist on escape failures. |
1997-04-10 |
2023-08-12 |
rat |