| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S B Floresco, J K Seamans, A G Phillip. A selective role for dopamine in the nucleus accumbens of the rat in random foraging but not delayed spatial win-shift-based foraging. Behavioural brain research. vol 80. issue 1-2. 1997-02-19. PMID:8905139. |
the role of mesoaccumbens dopamine (da) in radial-arm maze foraging is assessed by infusing low doses of the da antagonist haloperidol into the nucleus accumbens (n.acc.). |
1997-02-19 |
2023-08-12 |
rat |
| K Ossowska, M Pietraszek, J Warda. Further evidence for the subsensitivity of striatal AMPA receptors, induced by chronic haloperidol administration: an autoradiographic study. Naunyn-Schmiedeberg's archives of pharmacology. vol 354. issue 3. 1997-02-18. PMID:8878072. |
the aim of the present study was to investigate the influence of chronic treatment with haloperidol on the striatal n-methyl-d-aspartate (nmda), alpha-amino-3-hydroxy-5-methyl-4-isoxasole-propionic acid (ampa) and dopamine d2 receptors using a quantitative autoradiography in rats. |
1997-02-18 |
2023-08-12 |
rat |
| K Ossowska, M Pietraszek, J Warda. Further evidence for the subsensitivity of striatal AMPA receptors, induced by chronic haloperidol administration: an autoradiographic study. Naunyn-Schmiedeberg's archives of pharmacology. vol 354. issue 3. 1997-02-18. PMID:8878072. |
the present results suggest that, apart from supersensitivity to dopamine, chronic treatment with haloperidol also induces subsensitivity of striatal ampa receptors. |
1997-02-18 |
2023-08-12 |
rat |
| M E Gnegy, G H Hewlett, G Pimputka. Haloperidol and MK-801 block increases in striatal calmodulin resulting from repeated amphetamine treatment. Brain research. vol 734. issue 1-2. 1997-02-18. PMID:8896805. |
to determine whether the increase was related to development of amphetamine sensitization, we examined whether the increase in calmodulin would be blocked by the dopamine antagonist, haloperidol, or the nmda antagonist, mk-801. |
1997-02-18 |
2023-08-12 |
rat |
| A Ouagazzal, M Amalri. Competitive NMDA receptor antagonists do not produce locomotor hyperactivity by a dopamine-dependent mechanism. European journal of pharmacology. vol 294. issue 1. 1997-02-12. PMID:8788425. |
pharmacological blockade of dopamine receptors locally in the nucleus accumbens with haloperidol (5 micrograms/microliters) failed to reduce the locomotor effects of ap-5 (10 micrograms), but antagonized the effects induced by the non-competitive nmda receptor antagonist, mk-801 ((+)-5-methyl-10,11-dihydro(a,d)-cyclohepten-5,10-imine hydrogen maleate salt) (10 micrograms). |
1997-02-12 |
2023-08-12 |
rat |
| N Y Huang, R M Kostrzewa, C Li, K W Perry, R W Fulle. Persistent spontaneous oral dyskinesias in haloperidol-withdrawn rats neonatally lesioned with 6-hydroxydopamine: absence of an association with the Bmax for [3H]raclopride binding to neostriatal homogenates. The Journal of pharmacology and experimental therapeutics. vol 280. issue 1. 1997-02-10. PMID:8996206. |
to investigate the influence of dopamine (da) nerves on haloperidol (hal)-induced oral dyskinesias, rats were first injected at 3 days after birth with 6-hydroxydopamine hbr (200 micrograms i.c.v., salt form; 6-ohda) or vehicle, after desipramine hcl (20 mg/kg i.p., 1 hr) pretreatment. |
1997-02-10 |
2023-08-12 |
rat |
| D A Sakharov, E E Voronezhskaya, L Nezlin, M W Baker, K Elekes, R P Crol. Tyrosine hydroxylase-negative, dopaminergic neurons are targets for transmitter-depleting action of haloperidol in the snail brain. Cellular and molecular neurobiology. vol 16. issue 4. 1997-02-05. PMID:8879748. |
treatment by bath application with 0.5-2.0 micromolar haloperidol, caused a significant, continuous depletion of dopamine levels in the nervous system as revealed by high performance liquid chromatography. |
1997-02-05 |
2023-08-12 |
Not clear |
| D A Sakharov, E E Voronezhskaya, L Nezlin, M W Baker, K Elekes, R P Crol. Tyrosine hydroxylase-negative, dopaminergic neurons are targets for transmitter-depleting action of haloperidol in the snail brain. Cellular and molecular neurobiology. vol 16. issue 4. 1997-02-05. PMID:8879748. |
similar depletion of dopamine was observed after the land snail, achatina fulica, was injected with haloperidol on each of 4 consecutive days. |
1997-02-05 |
2023-08-12 |
Not clear |
| A Mele, C Castellano, A Felici, S Cabib, S Caccia, A Oliveri. Dopamine-N-methyl-D-aspartate interactions in the modulation of locomotor activity and memory consolidation in mice. European journal of pharmacology. vol 308. issue 1. 1997-01-30. PMID:8836626. |
the selective dopamine d1 receptor antagonist sch 23390 at doses up to 0.05 mg/kg was unable to affect mk-801-induced locomotor activity, while (-)-sulpiride, but only at high doses (30 mg/kg), and haloperidol (0.05 mg/kg) blocked the mk-801 effect. |
1997-01-30 |
2023-08-12 |
mouse |
| R A Padich, T C McCloskey, J H Kehn. 5-HT modulation of auditory and visual sensorimotor gating: II. Effects of the 5-HT2A antagonist MDL 100,907 on disruption of sound and light prepulse inhibition produced by 5-HT agonists in Wistar rats. Psychopharmacology. vol 124. issue 1-2. 1997-01-29. PMID:8935805. |
the d2 antagonist haloperidol was used to evaluate a possible interaction with dopamine neurons. |
1997-01-29 |
2023-08-12 |
rat |
| K A Yousef, J S Fowler, N D Volkow, S L Dewey, C Shea, D J Schlyer, S J Gatley, J Logan, A P Wol. [18F]haloperidol binding in baboon brain in vivo. Nuclear medicine and biology. vol 23. issue 1. 1997-01-27. PMID:9004914. |
the binding of [18f]haloperidol to dopamine d2 and to sigma recognition sites in baboon brain was examined using positron emission tomography (pet). |
1997-01-27 |
2023-08-12 |
Not clear |
| K A Yousef, J S Fowler, N D Volkow, S L Dewey, C Shea, D J Schlyer, S J Gatley, J Logan, A P Wol. [18F]haloperidol binding in baboon brain in vivo. Nuclear medicine and biology. vol 23. issue 1. 1997-01-27. PMID:9004914. |
studies were performed at baseline and after treatment with either haloperidol (to evaluate saturability), (+)-butaclamol (which has specificity for dopamine d2 receptors) or (-)-butaclamol (which has specificity for sigma sites). |
1997-01-27 |
2023-08-12 |
Not clear |
| K A Yousef, J S Fowler, N D Volkow, S L Dewey, C Shea, D J Schlyer, S J Gatley, J Logan, A P Wol. [18F]haloperidol binding in baboon brain in vivo. Nuclear medicine and biology. vol 23. issue 1. 1997-01-27. PMID:9004914. |
these results indicate that the binding profile of [18f]haloperidol does not permit the selective examination of either dopamine d2 or sigma sites using pet. |
1997-01-27 |
2023-08-12 |
Not clear |
| F Okada, A Ito, T Horikawa, Y Tokumitsu, Y Nomur. Long-term neuroleptic treatments counteract dopamine D2 agonist inhibition of adenylate cyclase but do not affect pertussis toxin ADP-ribosylation in the rat brain. Neurochemistry international. vol 28. issue 2. 1997-01-24. PMID:8719704. |
we have investigated the response of adenylate cyclase to gtp and to dopamine (da) in striatal membranes of rats treated for 3 weeks with chlorpromazine or haloperidol, and further measured the level of gi (an inhibitory gtp-binding protein) or go (a similar gtp-binding protein of unknown function) in 3 areas (cerebral cortex, striatum and hippocampus) utilizing pertussis toxin-catalyzed adp ribosylation. |
1997-01-24 |
2023-08-12 |
rat |
| Y Liu, S A Wolf. Haloperidol and spiperone potentiate murine splenic B cell proliferation. Immunopharmacology. vol 34. issue 2-3. 1997-01-23. PMID:8886859. |
therefore it is likely that the effects of haloperidol and spiperone are not due to actions at known dopamine, 5ht, alpha 1, or sigma receptors. |
1997-01-23 |
2023-08-12 |
Not clear |
| Y Mizuki, I Ushijima, M Yamad. Effects of chronic methamphetamine on SCH23390- or haloperidol-induced catalepsy, and effects of coadministration of SCH23390 or haloperidol in mice. Pharmacology, biochemistry, and behavior. vol 53. issue 2. 1997-01-16. PMID:8808155. |
the influence of chronic treatment of mice with methamphetamine, an indirect dopamine agonist, on the cataleptic effects of r-(+)-chloro-2,3,4,5,-tetrahydro-3-methyl-5-phenyl-1h-3-benzazepin -7ol hydrochloride (sch23390), a d1 receptor agonist, or haloperidol, a mainly d2 antagonist, was investigated. |
1997-01-16 |
2023-08-12 |
mouse |
| N Laprade, J J Soghomonia. Differential regulation of mRNA levels encoding for the two isoforms of glutamate decarboxylase (GAD65 and GAD67) by dopamine receptors in the rat striatum. Brain research. Molecular brain research. vol 34. issue 1. 1997-01-15. PMID:8750862. |
in the present experimental conditions, stimulation of dopamine receptors with apomorphine or skf-38393 resulted in increased gad65 mrna levels whereas blockade of dopamine receptors with haloperidol or sulpiride resulted in increased gad67 mrna levels. |
1997-01-15 |
2023-08-12 |
rat |
| A Dalia, N J Uretsky, L J Wallac. Induction of locomotor activity by the glutamate antagonist DNQX injected into the ventral tegmental area. Brain research. vol 728. issue 2. 1997-01-15. PMID:8864484. |
however, the locomotor stimulation produced by dnqx was markedly attenuated following blockade of dopaminergic receptors by haloperidol (0.5 mg/kg, s.c.) or following dopamine depletion induced by reserpine plus alpha-methyl-para-tyrosine pretreatment. |
1997-01-15 |
2023-08-12 |
Not clear |
| D C Main, A E Waterman, I C Kilpatric. Behavioural analysis of changes in nociceptive thresholds produced by remoxipride in sheep and rats. European journal of pharmacology. vol 287. issue 3. 1997-01-13. PMID:8991794. |
the antinociceptive, motor deficit and cataleptogenic actions of remoxipride were similar to those induced by two other dopamine antagonists, haloperidol (5 mg/kg) and raclopride (16 mg/kg i.p). |
1997-01-13 |
2023-08-12 |
rat |
| B M Rabi. Free radicals and taste aversion learning in the rat: nitric oxide, radiation and dopamine. Progress in neuro-psychopharmacology & biological psychiatry. vol 20. issue 4. 1997-01-03. PMID:8843492. |
pretreating rats with the dopamine antagonist haloperidol prevented the acquisition of the cta produced by snp and attenuated, but did not eliminate, the pbn-induced cta. |
1997-01-03 |
2023-08-12 |
rat |