| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| D C Wan, B Dean, G Pavey, D L Copolo. Treatment with haloperidol or clozapine causes changes in dopamine receptors but not adenylate cyclase or protein kinase C in the rat forebrain. Life sciences. vol 59. issue 23. 1997-01-02. PMID:8950299. |
treatment with haloperidol or clozapine causes changes in dopamine receptors but not adenylate cyclase or protein kinase c in the rat forebrain. |
1997-01-02 |
2023-08-12 |
rat |
| D C Wan, B Dean, G Pavey, D L Copolo. Treatment with haloperidol or clozapine causes changes in dopamine receptors but not adenylate cyclase or protein kinase C in the rat forebrain. Life sciences. vol 59. issue 23. 1997-01-02. PMID:8950299. |
the effect of treating rats with daily injections of haloperidol (1 mg/kg/day) or clozapine (20 mg/kg/day) for four weeks on second messengers and dopamine receptors was studied. |
1997-01-02 |
2023-08-12 |
rat |
| K Haraguchi, K Ito, Y Sawada, T Ig. Catalepsy induced by manidipine, a calcium channel blocker, in mice. The Journal of pharmacy and pharmacology. vol 48. issue 4. 1996-12-20. PMID:8794996. |
manidipine, flunarizine and haloperidol occupied both dopamine d1 and d2 receptors and d2-receptor occupancy was higher than d1-receptor occupancy. |
1996-12-20 |
2023-08-12 |
mouse |
| M E Old. Dopaminergic basis for the facilitation of brain stimulation reward by the NMDA receptor antagonist, MK-801. European journal of pharmacology. vol 306. issue 1-3. 1996-12-18. PMID:8813611. |
pretreatment of self-stimulators with the dopamine d1/d2 receptor antagonist, haloperidol, 0.2 mg/kg given i.p. |
1996-12-18 |
2023-08-12 |
rat |
| M Hasegawa, K Yamada, T Hasegawa, T Nabeshim. Role of dopaminergic neuronal system in dizocilpine-induced acetylcholine release in the rat brain. Journal of neural transmission (Vienna, Austria : 1996). vol 103. issue 6. 1996-12-17. PMID:8836927. |
the dopamine d2 receptor antagonist, haloperidol, showed dual effects similarly to alpha mpt, while the dopamine d1 receptor antagonist, sch23390, prolonged, but did not delay, the onset of the dizocilpine-induced increases in ach levels. |
1996-12-17 |
2023-08-12 |
rat |
| P Seema. Therapeutic receptor-blocking concentrations of neuroleptics. International clinical psychopharmacology. vol 10 Suppl 3. 1996-12-13. PMID:8866760. |
using the same considerations for haloperidol, it can be shown that the haloperidol therapeutic concentration required for 75% blockade of dopamine d2 receptors in vivo will be approximately 2-3 nm, in agreement with the observed value in the spinal fluid or plasma water of 1-3 nm. |
1996-12-13 |
2023-08-12 |
Not clear |
| K Y Wu, S J Hong, Y M Chun. Effects of dopamine antagonists and agonist on cultured human Tenon's fibroblast cells. The Kaohsiung journal of medical sciences. vol 12. issue 7. 1996-12-04. PMID:8753140. |
it was found that dopamine antagonists inhibited [3h]-thymidine uptake to 10.8%, 14.4%, 42.2% and 72.4% of control in domperidone, 28.6%, 67.7%, 96.9% and 99.2% in haloperidol, 9.8%, 18.9%, 103.5% and 104.6% in moperone and 9.8%, 24.7%, 70.8% and 96.9% in loxapine respectively, while the 0.5% concentration of drugs were dissolved in dimethyl sulfoxide (dmso) followed by dilution in culture medium to final concentrations ranging from 0.05%, 0.005%, 0.0005% to 0.00005%. |
1996-12-04 |
2023-08-12 |
human |
| B Gallhofer, U Bauer, S Lis, S Krieger, H Grupp. Cognitive dysfunction in schizophrenia: comparison of treatment with atypical antipsychotic agents and conventional neuroleptic drugs. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 6 Suppl 2. 1996-12-04. PMID:8792116. |
maze tests were used to determine the effects on cognition of conventional dopamine antagonist neuroleptics (haloperidol and fluphenazine) and the newer serotonin-dopamine antagonist antipsychotics (risperidone and clozapine). |
1996-12-04 |
2023-08-12 |
Not clear |
| M L Pucak, A A Grac. Effects of haloperidol on the activity and membrane physiology of substantia nigra dopamine neurons recorded in vitro. Brain research. vol 713. issue 1-2. 1996-12-03. PMID:8724974. |
effects of haloperidol on the activity and membrane physiology of substantia nigra dopamine neurons recorded in vitro. |
1996-12-03 |
2023-08-12 |
Not clear |
| M L Pucak, A A Grac. Effects of haloperidol on the activity and membrane physiology of substantia nigra dopamine neurons recorded in vitro. Brain research. vol 713. issue 1-2. 1996-12-03. PMID:8724974. |
in order to test this prediction, we have examined whether haloperidol alters the electrophysiological activity of dopamine neurons recorded from nigral slices maintained in vitro. |
1996-12-03 |
2023-08-12 |
Not clear |
| M L Pucak, A A Grac. Effects of haloperidol on the activity and membrane physiology of substantia nigra dopamine neurons recorded in vitro. Brain research. vol 713. issue 1-2. 1996-12-03. PMID:8724974. |
addition of haloperidol to the media bathing nigral slices caused increases in the spontaneous firing rate of some dopamine neurons. |
1996-12-03 |
2023-08-12 |
Not clear |
| J W Brock, C R Ashb. Evidence for genetically mediated dysfunction of the central dopaminergic system in the stargazer rat. Psychopharmacology. vol 123. issue 2. 1996-12-03. PMID:8741944. |
in this study, stargazers and their unaffected littermates were compared in their behavioral responses to both stimulation and inhibition of dopamine d2/d3 receptors, using quinpirole and haloperidol. |
1996-12-03 |
2023-08-12 |
rat |
| M F Egan, S J Chrapusta, F Karoum, R J Wyat. The effects of acute and chronic haloperidol treatment on dopamine release mediated by the medial forebrain bundle in the striatum and nucleus accumbens. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 14. issue 3. 1996-12-03. PMID:8866705. |
the effects of acute and chronic haloperidol treatment on dopamine release mediated by the medial forebrain bundle in the striatum and nucleus accumbens. |
1996-12-03 |
2023-08-12 |
rat |
| J L Góngora-Alfaro, S Hernández-López, D Martínez-Fong, G Flores, J Aceve. Circling behavior elicited by cholinergic transmission in the substantia nigra pars compacta: involvement of nicotinic and muscarinic receptors. Neuroscience. vol 71. issue 3. 1996-12-03. PMID:8867045. |
the circling was inhibited 93 +/- 3% by the dopamine antagonist haloperidol (53 nmol) injected into the neostriatum 90 min before the injection of physostigmine (37 nmol) into the ipsilateral substantia nigra pars compacta. |
1996-12-03 |
2023-08-12 |
rat |
| P Khosla, S Kothari, M C Gupta, R K Srivastav. Evaluation of haloperidol, a dopamine antagonist, on intraocular pressure in experimental glaucoma. Indian journal of experimental biology. vol 34. issue 6. 1996-11-27. PMID:8792645. |
evaluation of haloperidol, a dopamine antagonist, on intraocular pressure in experimental glaucoma. |
1996-11-27 |
2023-08-12 |
Not clear |
| V Bassareo, G Tanda, P Petromilli, C Giua, G Di Chiar. Non-psychostimulant drugs of abuse and anxiogenic drugs activate with differential selectivity dopamine transmission in the nucleus accumbens and in the medial prefrontal cortex of the rat. Psychopharmacology. vol 124. issue 4. 1996-11-25. PMID:8739543. |
systemic administration of low doses of the 5ht3 antagonist ics 205930, previously reported to prevent the increase of extracellular dopamine in the nucleus accumbens elicited by morphine, nicotine, ethanol and haloperidol (carboni et al. |
1996-11-25 |
2023-08-12 |
rat |
| C Ito, K Onodera, E Sakurai, M Sato, T Watanab. Effects of dopamine antagonists on neuronal histamine release in the striatum of rats subjected to acute and chronic treatments with methamphetamine. The Journal of pharmacology and experimental therapeutics. vol 279. issue 1. 1996-11-18. PMID:8859003. |
pretreatments with the dopamine d2 antagonists sulpiride and haloperidol blocked the meth-induced increase of ha release, whereas pretreatment with a dopamine d1 antagonist, sch23390, did not. |
1996-11-18 |
2023-08-12 |
rat |
| R J Boegman, S R Vincen. Involvement of adenosine and glutamate receptors in the induction of c-fos in the striatum by haloperidol. Synapse (New York, N.Y.). vol 22. issue 1. 1996-11-08. PMID:8822480. |
conversely, neuroleptic drugs, such as haloperidol, which block d2-type dopamine receptors, induce c-fos expression in striatal neurons projecting to the globus pallidus. |
1996-11-08 |
2023-08-12 |
Not clear |
| R E See, A M Lynch, M Aravagiri, C B Nemeroff, M J Owen. Chronic haloperidol-induced changes in regional dopamine release and metabolism and neurotensin content in rats. Brain research. vol 704. issue 2. 1996-10-31. PMID:8788915. |
these results suggest a confluence of altered dopamine and neurotensin function in the caudate putamen which may be related to motor side effects of haloperidol, whereas changes in prefrontal dopamine function are not associated with altered neurotensin levels. |
1996-10-31 |
2023-08-12 |
rat |
| R E See, A M Lynch, B A Sor. Subchronic administration of clozapine, but not haloperidol or metoclopramide, decreases dopamine D2 receptor messenger RNA levels in the nucleus accumbens and caudate-putamen in rats. Neuroscience. vol 72. issue 1. 1996-10-24. PMID:8730709. |
subchronic administration of clozapine, but not haloperidol or metoclopramide, decreases dopamine d2 receptor messenger rna levels in the nucleus accumbens and caudate-putamen in rats. |
1996-10-24 |
2023-08-12 |
rat |