| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Bourson, D Wanner, R Wyler, N Petit, C Zwingelstein, A Rudler, A J Sleigh. Pharmacologic evaluation of the discriminative stimulus of metachlorophenylpiperazine. Pharmacology, biochemistry, and behavior. vol 53. issue 1. 1996-10-24. PMID:8848438. |
haloperidol generalises, and amphetamine partially antagonises the mcpp discriminative cue and low doses of apomorphine partially generalises to the mcpp cue, which suggests that a decrease in dopamine neurotransmission may also be involved. |
1996-10-24 |
2023-08-12 |
rat |
| R J Rodgers, N J Johnson, A J Champion, S Mill. Modulation of plus-maze behaviour in mice by the preferential D3-receptor agonist 7-OH-DPAT. Pharmacology, biochemistry, and behavior. vol 54. issue 1. 1996-10-23. PMID:8728542. |
differences in the behavioural profiles of dopamine d2 receptor antagonists (e.g., haloperidol vs. sulpiride) in a animal models of anxiety have prompted speculation concerning the importance of their relative affinities for d2-like receptor populations. |
1996-10-23 |
2023-08-12 |
mouse |
| I Bodis-Wollner, A Anta. On the functional significance of primate retinal dopamine receptors. Journal of neural transmission. Supplementum. vol 45. 1996-10-23. PMID:8748611. |
studies were performed using haloperidol, 1-sulpiride, cy 208-243 and dopamine. |
1996-10-23 |
2023-08-12 |
human |
| A Imperato, M C Obinu, G L Gess. Is in vivo striatal acetylcholine output under a tonic inhibitory control by dopamine? Journal of neural transmission. Supplementum. vol 45. 1996-10-23. PMID:8748614. |
blockade of dopamine d2 receptors with (-)-sulpiride or haloperidol increased acetylcholine release to a maximum of 80% (after 50 and 0.5 mg/kg, respectively). |
1996-10-23 |
2023-08-12 |
rat |
| J T Cheng, T C Lin, F L Hs. Antihypertensive effect of corilagin in the rat. Canadian journal of physiology and pharmacology. vol 73. issue 10. 1996-10-23. PMID:8748933. |
failure of the antagonists for alpha2-adrenoceptors, idazoxan and yohimbine, as well as for dopamine receptors, haloperidol and domperidone, to reverse the antihypertensive actions of corilagin ruled out the participation of these receptors. |
1996-10-23 |
2023-08-12 |
rat |
| L Antkiewicz-Michaluk, B Karolewicz, J Michaluk, J Vetulan. Differences between haloperidol- and pimozide-induced withdrawal syndrome: a role for Ca2+ channels. European journal of pharmacology. vol 294. issue 2-3. 1996-10-23. PMID:8750706. |
after haloperidol treatment we observed an increase in cortical ca2+ channel and limbic dopamine d1 receptor density and an increase in spontaneous motor activity and apomorphine-induced hyperactivity and stereotypy. |
1996-10-23 |
2023-08-12 |
rat |
| K Ossowsk. The subsensitivity of striatal glutamate receptors induced by chronic haloperidol in rats. European journal of pharmacology. vol 294. issue 2-3. 1996-10-23. PMID:8750734. |
the present results seem to suggest that, apart from supersensitivity to dopamine, chronic treatment with haloperidol also induces subsensitivity of striatal nmda and non-nmda receptors. |
1996-10-23 |
2023-08-12 |
rat |
| J P Doucet, Y Nakabeppu, P J Bedard, B T Hope, E J Nestler, B J Jasmin, J S Chen, M J Iadarola, M St-Jean, N Wigle, P Blanchet, R Grondin, G S Robertso. Chronic alterations in dopaminergic neurotransmission produce a persistent elevation of deltaFosB-like protein(s) in both the rodent and primate striatum. The European journal of neuroscience. vol 8. issue 2. 1996-10-22. PMID:8714707. |
chronic haloperidol administration also selectively elevated expression of these fos-related antigens, suggesting that their induction after dopaminergic denervation is mediated by reduced activation of d2-like dopamine receptors. |
1996-10-22 |
2023-08-12 |
rat |
| A J Chesi, K J Feasey-Truger, C Alzheimer, G ten Bruggencat. Dopamine autoreceptor sensitivity is unchanged in rat nucleus accumbens after chronic haloperidol treatment: an in vivo and in vitro voltammetric study. The European journal of neuroscience. vol 7. issue 12. 1996-10-22. PMID:8845950. |
dopamine autoreceptor sensitivity is unchanged in rat nucleus accumbens after chronic haloperidol treatment: an in vivo and in vitro voltammetric study. |
1996-10-22 |
2023-08-12 |
rat |
| A J Chesi, K J Feasey-Truger, C Alzheimer, G ten Bruggencat. Dopamine autoreceptor sensitivity is unchanged in rat nucleus accumbens after chronic haloperidol treatment: an in vivo and in vitro voltammetric study. The European journal of neuroscience. vol 7. issue 12. 1996-10-22. PMID:8845950. |
fast cyclic voltammetry was used to assess the effects of chronic oral haloperidol treatment (0.7 mg/kg/day for 21 days) on the sensitivity of dopamine autoreceptors in the rat nucleus accumbens both in vivo and in vitro. |
1996-10-22 |
2023-08-12 |
rat |
| A J Chesi, K J Feasey-Truger, C Alzheimer, G ten Bruggencat. Dopamine autoreceptor sensitivity is unchanged in rat nucleus accumbens after chronic haloperidol treatment: an in vivo and in vitro voltammetric study. The European journal of neuroscience. vol 7. issue 12. 1996-10-22. PMID:8845950. |
evoked dopamine overflow was significantly reduced after chronic haloperidol treatment, but the sensitivity of dopamine overflow to sulpiride, an antagonist at release-inhibiting dopamine autoreceptors, and quinpirole, an agonist at these receptors, was unchanged. |
1996-10-22 |
2023-08-12 |
rat |
| A J Chesi, K J Feasey-Truger, C Alzheimer, G ten Bruggencat. Dopamine autoreceptor sensitivity is unchanged in rat nucleus accumbens after chronic haloperidol treatment: an in vivo and in vitro voltammetric study. The European journal of neuroscience. vol 7. issue 12. 1996-10-22. PMID:8845950. |
the finding that the reduced dopamine overflow in the nucleus accumbens observed after chronic treatment with a classical neuroleptic is not due to dopamine autoreceptor supersensitivity may therefore be the first functional evidence for unchanged autoreceptor activity in the nucleus accumbens, supporting biochemical findings of a lack of d3 autoreceptor up-regulation after chronic haloperidol treatment. |
1996-10-22 |
2023-08-12 |
rat |
| I Ushijima, Y Mizuki, M Yamad. Alteration of cataleptic responses induced by dopamine receptor antagonists after chronic cocaine administration in mice. European journal of pharmacology. vol 285. issue 1. 1996-10-21. PMID:8846811. |
the influence of chronic treatment of mice with cocaine, an indirect dopamine receptor agonist, on the cataleptic effects of r-(+)-chloro-2,3,4,5-tetrahydro-3-methyl-5-phenyl-1h-3-benzazepin- 7ol hydrochloride (sch23390), a dopamine d1 receptor antagonist, or haloperidol, mainly a dopamine d2 receptor antagonist, was investigated. |
1996-10-21 |
2023-08-12 |
mouse |
| H L Andersen, I C Kilpatric. Prevention by (+/-)-8-hydroxy-2-(di-n-propylamino)tetralin of both catalepsy and the rises in rat striatal dopamine metabolism caused by haloperidol. British journal of pharmacology. vol 118. issue 2. 1996-10-16. PMID:8735647. |
prevention by (+/-)-8-hydroxy-2-(di-n-propylamino)tetralin of both catalepsy and the rises in rat striatal dopamine metabolism caused by haloperidol. |
1996-10-16 |
2023-08-12 |
rat |
| H L Andersen, I C Kilpatric. Prevention by (+/-)-8-hydroxy-2-(di-n-propylamino)tetralin of both catalepsy and the rises in rat striatal dopamine metabolism caused by haloperidol. British journal of pharmacology. vol 118. issue 2. 1996-10-16. PMID:8735647. |
these results suggest that part of the mechanism by which 8-oh-dpat prevents haloperidol-induced catalepsy is reflected by a reversal of the compensatory increase in meso-striatal and/or meso-cortical dopamine neuronal activity that normally accompanies postsynaptic dopamine receptor blockade with haloperidol. |
1996-10-16 |
2023-08-12 |
rat |
| b' R R Ga\\xc4\\xadnetdinov, K S Raevski\\xc4\\xa. [Substances that increase the extracellular level of dopamine in the striatum prevent development of haloperidol catalepsy in rats]. Biulleten\' eksperimental\'noi biologii i meditsiny. vol 121. issue 4. 1996-10-16. PMID:8829461.' |
[substances that increase the extracellular level of dopamine in the striatum prevent development of haloperidol catalepsy in rats]. |
1996-10-16 |
2023-08-12 |
rat |
| P H Van der Graaf, P R Saxena, N P Shankley, J W Blac. Exposure and characterization of the action of noradrenaline at dopamine receptors mediating endothelium-independent relaxation of rat isolated small mesenteric arteries. British journal of pharmacology. vol 116. issue 8. 1996-10-10. PMID:8719802. |
however, haloperidol (10 microm) and (+/-)-sch-23390 (10 nm) produced significant inhibition of the relaxation, suggesting the involvement of dopamine d1 receptors. |
1996-10-10 |
2023-08-12 |
rat |
| P H Van der Graaf, P R Saxena, N P Shankley, J W Blac. Exposure and characterization of the action of noradrenaline at dopamine receptors mediating endothelium-independent relaxation of rat isolated small mesenteric arteries. British journal of pharmacology. vol 116. issue 8. 1996-10-10. PMID:8719802. |
dopamine also produced concentration-dependent relaxation following u46619 precontraction (pic50 = 5.4 +/- 0.1) which was significantly inhibited by haloperidol and (+)-sch-23390. |
1996-10-10 |
2023-08-12 |
rat |
| I M Conceição, R Frussa-Filh. Effects of microgram doses of haloperidol on open-field behavior in mice. Pharmacology, biochemistry, and behavior. vol 53. issue 4. 1996-09-30. PMID:8801585. |
a differential action of haloperidol on dopamine receptors mediating motor stimulation and motor depression was proposed. |
1996-09-30 |
2023-08-12 |
mouse |
| B A Morrow, J D Elsworth, R H Rot. Tyrosine enhances behavioral and mesocorticolimbic dopaminergic responses to aversive conditioning. Synapse (New York, N.Y.). vol 22. issue 2. 1996-09-26. PMID:8787125. |
additionally, exogenous tyrosine has been demonstrated to enhance the pharmacologically-induced increase in dopamine metabolism seen following administration of haloperidol or the anxiogenic b-carboline, fg-7142. |
1996-09-26 |
2023-08-12 |
rat |