| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| W Wan, D J Ennulat, B M Cohe. Acute administration of typical and atypical antipsychotic drugs induces distinctive patterns of Fos expression in the rat forebrain. Brain research. vol 688. issue 1-2. 1996-02-14. PMID:8542328. |
administration of single doses of a wide range of typical neuroleptic antipsychotic drugs (including the potent dopamine d2 antagonist haloperidol and the mixed monoamine antagonist chlorpromazine) and atypical antipsychotic drugs (including the weak dopamine d2 antagonists clozapine and thioridazine, the relatively pure d2 antagonist raclopride and the mixed d2 and serotonin s2 antagonist risperidone). |
1996-02-14 |
2023-08-12 |
rat |
| B Ziolkowska, G Horn, A Kupsch, V Höll. The expression of proenkephalin and prodynorphin genes and the induction of c-fos gene by dopaminergic drugs are not altered in the straitum of MPTP-treated mice. Journal of neural transmission. Parkinson's disease and dementia section. vol 9. issue 2-3. 1996-02-01. PMID:8527000. |
the induction of the immediate early gene c-fos by the dopamine d2 receptor antagonist haloperidol was not altered, while the selective d1 receptor agonist skf 38393 failed to induce c-fos in the striatum of mptp-treated mice. |
1996-02-01 |
2023-08-12 |
mouse |
| F Sautel, N Griffon, P Sokoloff, J C Schwartz, C Launay, P Simon, J Costentin, A Schoenfelder, F Garrido, A Man. Nafadotride, a potent preferential dopamine D3 receptor antagonist, activates locomotion in rodents. The Journal of pharmacology and experimental therapeutics. vol 275. issue 3. 1996-02-01. PMID:8531087. |
at low dosage (0.1-1 mg/kg), nafadotride, unlike haloperidol, a dopamine d2 receptor-preferring antagonist, increases spontaneous locomotion of habituated rats and climbing behavior of mice, at doses that do not modify striatal homovanillic acid levels. |
1996-02-01 |
2023-08-12 |
mouse |
| M Didrikse. Effects of antipsychotics on cognitive behaviour in rats using the delayed non-match to position paradigm. European journal of pharmacology. vol 281. issue 3. 1996-01-25. PMID:8521906. |
the acute effects of the dopamine d1 receptor antagonist sch 23390 [(r)-(+)-8-chloro-2,3,4,5-tetrahydro-3-methyl-5-phenyl-1h-3-benzazepi n-7-ol d hemimaleat, the dopamine d2 receptor antagonists raclopride and haloperidol, the compounds with mixed receptor profiles clozapine, risperidone and sertindole, the alpha 1-adrenoceptor antagonist prazosin and scopolamine were investigated in a delay-response task, a test for working memory, for rats. |
1996-01-25 |
2023-08-12 |
rat |
| D M Jackson, N Mohell, A Bengtsson, A Malmber. Why does clozapine stimulate the motor activity of reserpine-pretreated rats when combined with a dopamine D1 receptor agonist? European journal of pharmacology. vol 282. issue 1-3. 1996-01-18. PMID:7498268. |
the stimulation produced by clozapine plus skf38393 was blocked by the selective dopamine d1 receptor antagonist, sch23390 (7-chloro-8-hydroxy-3-methyl-1-phenyl-2,3,4,5- tetrahydro-1h-3-benzapine hydrochloride), while the selective dopamine d2 receptor antagonist, haloperidol, was ineffective. |
1996-01-18 |
2023-08-12 |
rat |
| D M Jackson, N Mohell, A Bengtsson, A Malmber. Why does clozapine stimulate the motor activity of reserpine-pretreated rats when combined with a dopamine D1 receptor agonist? European journal of pharmacology. vol 282. issue 1-3. 1996-01-18. PMID:7498268. |
unlike clozapine, neither the selective 5-ht2 receptor antagonist, ritanserin, nor the dopamine d2 receptor antagonists, haloperidol and remoxipride, caused locomotor activation when given alone or in combination with skf38393. |
1996-01-18 |
2023-08-12 |
rat |
| H Sasaki, K Hashimoto, T Inada, S Fukui, M Iy. Suppression of oro-facial movements by rolipram, a cAMP phosphodiesterase inhibitor, in rats chronically treated with haloperidol. European journal of pharmacology. vol 282. issue 1-3. 1996-01-18. PMID:7498291. |
haloperidol treatment significantly increased dyskinetic movements and striatal dopamine d2 receptor density compared with controls. |
1996-01-18 |
2023-08-12 |
rat |
| J Arn. Differential effects of classical and newer antipsychotics on the hypermotility induced by two dose levels of D-amphetamine. European journal of pharmacology. vol 283. issue 1-3. 1996-01-18. PMID:7498321. |
classical antipsychotics (haloperidol, fluphenazine and cis(z)-flupentixol) and the selective dopamine d2 receptor antagonist remoxipride inhibit hypermotility in the two conditions with similar potencies, whereas sertindole, clozapine, risperidone, ziprasidone and olanzapine preferentially inhibit the effect of the low dose of d-amphetamine (selectivity ratios between 6.5 and 18). |
1996-01-18 |
2023-08-12 |
Not clear |
| N S Magoski, L G Bauce, N I Syed, A G Bulloc. Dopaminergic transmission between identified neurons from the mollusk, Lymnaea stagnalis. Journal of neurophysiology. vol 74. issue 3. 1996-01-18. PMID:7500151. |
several dopamine antagonists were used in an attempt to block rped1's synapses: chlorpromazine, ergonovine, fluphenazine, haloperidol, 6-hydroxydopamine, sch 23390, (+/-) sulpiride, and tubocurarine. |
1996-01-18 |
2023-08-12 |
Not clear |
| C V Borlongan, R Martinez, R D Shytle, T B Freeman, D W Cahill, P R Sanber. Striatal dopamine-mediated motor behavior is altered following occlusion of the middle cerebral artery. Pharmacology, biochemistry, and behavior. vol 52. issue 1. 1996-01-16. PMID:7501669. |
ischemic animals exhibited significantly less dopamine antagonist (haloperidol)-induced catalepsy and more dopamine agonist (amphetamine)-induced hyperactivity than sham-operated animals. |
1996-01-16 |
2023-08-12 |
rat |
| B Jardon, N Bonaventur. Different effects of dopamine and piribedil (a dopamine D2 agonist) on frog monocular optokinetic nystagmus asymmetry. Vision research. vol 35. issue 19. 1995-12-12. PMID:7483308. |
conversely, dopamine or haloperidol (a dopamine antagonist, acting mainly on d2 receptors) have no effect upon the monocular okn unidirectionality. |
1995-12-12 |
2023-08-12 |
Not clear |
| H Kuribar. Contrasting effects on methamphetamine sensitization of ceruletide, a cholecystokinin-like decapeptide, and haloperidol. Psychopharmacology. vol 120. issue 1. 1995-12-07. PMID:7480538. |
ceruletide, a cholecystokinin-like decapeptide, and haloperidol show neuroleptic actions through inhibition of dopamine release and blockade of dopamine receptors, respectively. |
1995-12-07 |
2023-08-12 |
mouse |
| S Maurel-Remy, K Bervoets, M J Milla. Blockade of phencyclidine-induced hyperlocomotion by clozapine and MDL 100,907 in rats reflects antagonism of 5-HT2A receptors. European journal of pharmacology. vol 280. issue 2. 1995-12-07. PMID:7589172. |
in analogy to haloperidol, the selective dopamine d2 receptor antagonist, raclopride, antagonised amphetamine (0.16) more potently than pcp (0.8) whereas the selective 5-ht2a receptor antagonist, [r(+)-alpha-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenylethyl)]-4- piperidine-methanol] (mdl 100,907), only antagonised pcp (0.001) as compared to amphetamine (> 10.0). |
1995-12-07 |
2023-08-12 |
rat |
| M J Millan, V Audinot, C Melon, A Newman-Tancred. Evidence that dopamine D3 receptors participate in clozapine-induced hypothermia. European journal of pharmacology. vol 280. issue 2. 1995-12-07. PMID:7589191. |
haloperidol and raclopride, mixed dopamine d2/d3 receptor antagonists, failed, in contrast, to modify core temperature. |
1995-12-07 |
2023-08-12 |
human |
| B Parsons, D M Togasaki, S Kassir, S Przedborsk. Neuroleptics up-regulate adenosine A2a receptors in rat striatum: implications for the mechanism and the treatment of tardive dyskinesia. Journal of neurochemistry. vol 65. issue 5. 1995-12-04. PMID:7595490. |
in contrast, haloperidol had no such effect on striatal dopamine subtype-1 (d1) and adenosine subtype-1 (a1) receptors. |
1995-12-04 |
2023-08-12 |
rat |
| T I Lidsky, J S Schneider, E Yablonsky-Alter, L G Zuck, S P Banerje. Taurine prevents haloperidol-induced changes in striatal neurochemistry and behavior. Brain research. vol 686. issue 1. 1995-11-28. PMID:7583261. |
repeated daily administration of haloperidol produces changes in striatal neurochemistry (decreased dopamine synthesis, upregulation of d2 receptors) and behavior (increasing catalepsy). |
1995-11-28 |
2023-08-12 |
Not clear |
| M Ozaki, Y Miyamoto, S Kishioka, Y Masuda, H Yamamot. The dopaminergic system modulates the endogenous opioid system in guinea-pig isolated ileal longitudinal muscle. Neuropharmacology. vol 34. issue 5. 1995-11-22. PMID:7566480. |
the effects of the dopamine antagonists haloperidol and sultopride were investigated on the twitch response, evoked by 0.1 hz stimulation of guinea-pig isolated ileal longitudinal muscle, and on the inhibition of the twitch response induced by 10 hz stimulation (post-tetanic twitch inhibition) and by application of opioids. |
1995-11-22 |
2023-08-12 |
Not clear |
| M Volonté, A Ceci, F Borsin. Effect of the 5-hydroxytryptamine3 receptor antagonist itasetron (DAU 6215) on (+)-N-allylnormetazocine-induced dopamine release in the nucleus accumbens and in the corpus striatum of the rat: an in vivo microdialysis study. The Journal of pharmacology and experimental therapeutics. vol 275. issue 1. 1995-11-21. PMID:7562571. |
the in vivo brain microdialysis technique has been used to study the ability of itasetron, [dau 6215, (3-alpha-tropanyl)1h-benzimidazolone-3-carboxamide hydrochloride], a novel 5-hydroxytryptamine3 (5-ht3)-receptor antagonist, to antagonize the effect of the sigma-agonist (+)-n-allylnormetazocine (skf 10,047) in inducing the release of dopamine from mesolimbic and nigrostriatal dopaminergic neurons, in comparison with haloperidol and clozapine. |
1995-11-21 |
2023-08-12 |
rat |
| L A Shapiro, S J Offord, G A Ordwa. The effect of chronic treatment with a novel aryl-piperazine antipsychotic on monoamine receptors in rat brain. Brain research. vol 677. issue 2. 1995-11-14. PMID:7552250. |
binding to d2 dopamine receptors was significantly elevated in the caudate-putamen of rats treated with haloperidol or rwj 37796 as compared to controls. |
1995-11-14 |
2023-08-12 |
rat |
| L A Shapiro, S J Offord, G A Ordwa. The effect of chronic treatment with a novel aryl-piperazine antipsychotic on monoamine receptors in rat brain. Brain research. vol 677. issue 2. 1995-11-14. PMID:7552250. |
haloperidol treatment also increased binding (+35%) to d2 dopamine receptors in the nucleus accumbens, where rwj 37796 treatment had a considerably smaller effect (+12). |
1995-11-14 |
2023-08-12 |
rat |