| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| K A Yousef, N D Volkow, D J Schlyer, J S Fowler, A P Wolf, G J Wang, M R Smith, J D Brodie, D Warne. Haloperidol blocks the uptake of [18F]N-methylspiroperidol by extrastriatal dopamine receptors in schizophrenic patients. Synapse (New York, N.Y.). vol 19. issue 1. 1995-05-09. PMID:7709339. |
haloperidol blocks the uptake of [18f]n-methylspiroperidol by extrastriatal dopamine receptors in schizophrenic patients. |
1995-05-09 |
2023-08-12 |
human |
| K A Yousef, N D Volkow, D J Schlyer, J S Fowler, A P Wolf, G J Wang, M R Smith, J D Brodie, D Warne. Haloperidol blocks the uptake of [18F]N-methylspiroperidol by extrastriatal dopamine receptors in schizophrenic patients. Synapse (New York, N.Y.). vol 19. issue 1. 1995-05-09. PMID:7709339. |
haloperidol's ability to block the uptake of 18f-nms is an indication of the specificity of the radioligand's binding in these regions and supports the postmortem data demonstrating the presence of dopamine d2 receptors in the thalamus and temporal cortex of the human brain. |
1995-05-09 |
2023-08-12 |
human |
| M Koch, M Bubse. Deficient sensorimotor gating after 6-hydroxydopamine lesion of the rat medial prefrontal cortex is reversed by haloperidol. The European journal of neuroscience. vol 6. issue 12. 1995-05-05. PMID:7704295. |
systemic administration of the dopamine antagonist haloperidol (0.05 mg/kg), which did not affect prepulse inhibition in sham-lesioned and in 6-ohdabup rats, antagonized the lesion-induced deficit in prepulse inhibition in 6-ohdadmi rats. |
1995-05-05 |
2023-08-12 |
rat |
| G Mereu, V Lilliu, P Vargiu, A L Muntoni, M Diana, G L Gess. Failure of chronic haloperidol to induce depolarization inactivation of dopamine neurons in unanesthetized rats. European journal of pharmacology. vol 264. issue 3. 1995-04-28. PMID:7698187. |
failure of chronic haloperidol to induce depolarization inactivation of dopamine neurons in unanesthetized rats. |
1995-04-28 |
2023-08-12 |
rat |
| G Mereu, V Lilliu, P Vargiu, A L Muntoni, M Diana, G L Gess. Failure of chronic haloperidol to induce depolarization inactivation of dopamine neurons in unanesthetized rats. European journal of pharmacology. vol 264. issue 3. 1995-04-28. PMID:7698187. |
in agreement with previous studies, where neuronal sampling was carried out in animals under chloral hydrate anesthesia, chronic treatment with haloperidol (0.5 mg/kg daily for 21-28 days) produced a marked reduction (about 80%) in the number of spontaneously active dopamine neurons. |
1995-04-28 |
2023-08-12 |
rat |
| M E Gnegy, A Agrawal, K Hewlett, E Yeung, S Ye. Repeated haloperidol increases both calmodulin and a calmodulin-binding protein in rat striatum. Brain research. Molecular brain research. vol 27. issue 2. 1995-04-25. PMID:7898303. |
repeated treatment with the antipsychotic drug, haloperidol, leads to an increased behavioral sensitivity to dopamine agonists exhibited upon withdrawal from the drug. |
1995-04-25 |
2023-08-12 |
rat |
| M E Gnegy, A Agrawal, K Hewlett, E Yeung, S Ye. Repeated haloperidol increases both calmodulin and a calmodulin-binding protein in rat striatum. Brain research. Molecular brain research. vol 27. issue 2. 1995-04-25. PMID:7898303. |
challenge with the dopamine mimetic, amphetamine, before sacrifice was effective in redistributing calmodulin only in striatum from rats that had been treated repeatedly with haloperidol, demonstrating an increased sensitivity of the translocation process. |
1995-04-25 |
2023-08-12 |
rat |
| G Y Ng, S R Georg. Dopamine receptor agonist reduces ethanol self-administration in the ethanol-preferring C57BL/6J inbred mouse. European journal of pharmacology. vol 269. issue 3. 1995-04-24. PMID:7895775. |
in these mice, treatment with the dopamine d2 receptor antagonist haloperidol led to a 28% reduction in the absolute amount of ethanol consumed, but not in voluntary ethanol preference. |
1995-04-24 |
2023-08-12 |
mouse |
| S Ferré, R Schwarcz, X M Li, P Snaprud, S O Ogren, K Fux. Chronic haloperidol treatment leads to an increase in the intramembrane interaction between adenosine A2 and dopamine D2 receptors in the neostriatum. Psychopharmacology. vol 116. issue 3. 1995-04-20. PMID:7892417. |
chronic haloperidol treatment leads to an increase in the intramembrane interaction between adenosine a2 and dopamine d2 receptors in the neostriatum. |
1995-04-20 |
2023-08-12 |
rat |
| P M Iuvone, J Ga. Functional interaction of melatonin receptors and D1 dopamine receptors in cultured chick retinal neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 15. issue 3 Pt 2. 1995-04-17. PMID:7534345. |
this effect of dopamine was antagonized by addition of dopamine receptor antagonists (haloperidol and sch23390) or melatonin receptor agonists (melatonin, 2-iodomelatonin, and 6-chloromelatonin). |
1995-04-17 |
2023-08-12 |
chicken |
| A Verma, S K Kulkarn. D1/D2 dopamine and N-methyl-D-aspartate (NMDA) receptor participation in experimental catalepsy in rats. Psychopharmacology. vol 109. issue 4. 1995-04-04. PMID:1365866. |
mixed d1/d2 dopamine (da) antagonists, perphenazine (5 mg/kg) and haloperidol (2 mg/kg) induced catalepsy in rats. |
1995-04-04 |
2023-08-11 |
rat |
| J B Zawilska, T Derbiszewska, J Z Nowa. Clozapine and other neuroleptic drugs antagonize the light-evoked suppression of melatonin biosynthesis in chick retina: involvement of the D4-like dopamine receptor. Journal of neural transmission. General section. vol 97. issue 2. 1995-04-04. PMID:7873121. |
pretreatment of chicks with neuroleptic drugs--blockers of the d2-family of dopamine receptors, i.e., clotiapine, clozapine (an atypical neuroleptic with high affinity for a d4-subtype dopamine receptor), haloperidol, spiroperidol, sulpiride, and ym-09151-2, significantly antagonized the light-evoked suppression of the nighttime nat activity of the chick retina in a dose-dependent manner. |
1995-04-04 |
2023-08-12 |
chicken |
| H Kinoshita, T Hasegawa, Y Katsumata, T Kameyama, I Yamamoto, T Nabeshim. Effect of dizocilpine (MK-801) on the catalepsy induced by delta 9-tetrahydrocannabinol in mice. Journal of neural transmission. General section. vol 95. issue 2. 1995-03-30. PMID:7865168. |
furthermore, the anticataleptic effect of mk-801 on thc-induced catalepsy was blocked by acetylcholine agonist oxotremorine (0.005 mg/kg) and dopamine antagonist haloperidol (0.01 mg/kg), but not by nmda. |
1995-03-30 |
2023-08-12 |
mouse |
| J Reiriz, S Ambrosio, A Cobos, M Ballarín, E Tolosa, N Mah. Dopaminergic function in rat brain after oral administration of calcium-channel blockers or haloperidol. A microdialysis study. Journal of neural transmission. General section. vol 95. issue 3. 1995-03-30. PMID:7865175. |
acute flunarizine, nicardipine or haloperidol increased extracellular levels of dopamine (da) or metabolites. |
1995-03-30 |
2023-08-12 |
rat |
| J Reiriz, S Ambrosio, A Cobos, M Ballarín, E Tolosa, N Mah. Dopaminergic function in rat brain after oral administration of calcium-channel blockers or haloperidol. A microdialysis study. Journal of neural transmission. General section. vol 95. issue 3. 1995-03-30. PMID:7865175. |
after repeated (18 days) administration, nicardipine, nifedipine, verapamil or haloperidol increased and flunarizine decreased extracellular striatal levels of dopamine or metabolites. |
1995-03-30 |
2023-08-12 |
rat |
| J Reiriz, S Ambrosio, A Cobos, M Ballarín, E Tolosa, N Mah. Dopaminergic function in rat brain after oral administration of calcium-channel blockers or haloperidol. A microdialysis study. Journal of neural transmission. General section. vol 95. issue 3. 1995-03-30. PMID:7865175. |
chronic treatment with calcium-channel blockers or haloperidol failed to block k(+)-evoked release of dopamine. |
1995-03-30 |
2023-08-12 |
rat |
| J M Goldstein, L C Litwin, E B Sutton, J B Malic. Seroquel: electrophysiological profile of a potential atypical antipsychotic. Psychopharmacology. vol 112. issue 2-3. 1995-03-30. PMID:7871033. |
seroquel and clozapine were differentially more active in reversing the inhibitory actions of d-amphetamine on mesolimbic (a10) than nigrostriatal (a9) dopamine (da)-containing neurons, whereas haloperidol exhibited the opposite selectivity. |
1995-03-30 |
2023-08-12 |
Not clear |
| H Lublin, J Gerlach, L Peacoc. Chronic treatment with the D1 receptor antagonist, SCH 23390, and the D2 receptor antagonist, raclopride, in cebus monkeys withdrawn from previous haloperidol treatment. Extrapyramidal syndromes and dopaminergic supersensitivity. Psychopharmacology. vol 112. issue 2-3. 1995-03-30. PMID:7871047. |
the effects of chronic treatment with dopamine (da) d1 and d2 receptor antagonists were evaluated in eight cebus apella monkeys with mild oral dyskinesia after previous haloperidol treatment. |
1995-03-30 |
2023-08-12 |
monkey |
| K Kitaichi, K Yamada, T Hasegawa, H Furukawa, T Nabeshim. Effects of risperidone on phencyclidine-induced behaviors: comparison with haloperidol and ritanserin. Japanese journal of pharmacology. vol 66. issue 2. 1995-03-29. PMID:7532732. |
neurochemically, the increasing effects of risperidone on the content of dopac and the ratio of dopac to dopamine in the striatum were lower than those of haloperidol. |
1995-03-29 |
2023-08-12 |
rat |
| S O Ogren, M Goldstei. Phencyclidine- and dizocilpine-induced hyperlocomotion are differentially mediated. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 11. issue 3. 1995-03-29. PMID:7865098. |
the dopamine (da) d2 agonist quinpirole and the d2 receptor antagonists, haloperidol, raclopride, and remoxipride, were examined for their ability to block the locomotion induced by the noncompetitive n-methyl-d-aspartate (nmda) receptor antagonists phencyclidine (pcp) and dizocilpine, both given in equipotent doses. |
1995-03-29 |
2023-08-12 |
Not clear |