| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J G Csernansky, C T Wrona, M E Bardgett, T S Early, J W Newcome. Subcortical dopamine and serotonin turnover during acute and subchronic administration of typical and atypical neuroleptics. Psychopharmacology. vol 110. issue 1-2. 1995-03-29. PMID:7870875. |
the effects of acute (1 day) and subchronic (28 days) treatment with three atypical antipsychotic drugs [clozapine, (+/-)-sulpiride and (-)-3-ppp] on dopamine and serotonin turnover in both the nucleus accumbens (na) and corpus striatum (cs) of rodents was compared to haloperidol and saline treatment. |
1995-03-29 |
2023-08-12 |
Not clear |
| J G Csernansky, C T Wrona, M E Bardgett, T S Early, J W Newcome. Subcortical dopamine and serotonin turnover during acute and subchronic administration of typical and atypical neuroleptics. Psychopharmacology. vol 110. issue 1-2. 1995-03-29. PMID:7870875. |
all three atypical drugs, compared to haloperidol, produced preferential elevations of dopamine turnover in the na. |
1995-03-29 |
2023-08-12 |
Not clear |
| Y Hatta, S Hatta, T Sait. Effects of ceruletide on the dopamine receptor-adenylate cyclase system in striatum and frontal cortex of rats chronically treated with haloperidol. Psychopharmacology. vol 110. issue 4. 1995-03-29. PMID:7870906. |
effects of ceruletide on the dopamine receptor-adenylate cyclase system in striatum and frontal cortex of rats chronically treated with haloperidol. |
1995-03-29 |
2023-08-12 |
rat |
| I Szelenyi, H Herold, M Göther. Emesis induced in domestic pigs: a new experimental tool for detection of antiemetic drugs and for evaluation of emetogenic potential of new anticancer agents. Journal of pharmacological and toxicological methods. vol 32. issue 2. 1995-03-28. PMID:7865862. |
the more selective dopamine d2 receptor antagonists, alizapride and domperidone, even at high doses (25-50 mg/pig; approximately 0.8-1.6 mg/kg), did not inhibit cisplatin-induced emesis, nor did haloperidol up to 20 mg/pig (approximately 0.6 mg/kg). |
1995-03-28 |
2023-08-12 |
Not clear |
| C A Fox, A Mansour, S J Watso. The effects of haloperidol on dopamine receptor gene expression. Experimental neurology. vol 130. issue 2. 1995-03-27. PMID:7867758. |
haloperidol is a widely prescribed antipsychotic that acts as a dopamine d2 receptor antagonist. |
1995-03-27 |
2023-08-12 |
rat |
| C A Fox, A Mansour, S J Watso. The effects of haloperidol on dopamine receptor gene expression. Experimental neurology. vol 130. issue 2. 1995-03-27. PMID:7867758. |
this study examines the effects of haloperidol on dopaminoceptive striatal neurons, as well as dopamine d2 containing striatal inputs. |
1995-03-27 |
2023-08-12 |
rat |
| M J Ginski, J M Witki. Sensitive and rapid behavioral differentiation of N-methyl-D-aspartate receptor antagonists. Psychopharmacology. vol 114. issue 4. 1995-03-16. PMID:7855218. |
competitive nmda antagonists (ly 274614, ly 233536, cpp, npc 12626), sigma receptor ligands (dtg, dextromethorphan), postsynaptic dopamine agonists (quinpirole, skf 38393) and antagonists (haloperidol, sch 39166), and some depressant compounds (morphine, diazepam) increased failures on the screen test but decreased locomotor activity. |
1995-03-16 |
2023-08-12 |
mouse |
| M Kuoppamäki, T Seppälä, E Syvälahti, J Hietal. Regulation of serotonin 5-HT2C receptors in the rat choroid plexus after acute clozapine treatment. European journal of pharmacology. vol 269. issue 2. 1995-03-10. PMID:7851496. |
for comparison, both doses of clozapine, unlike haloperidol, decreased equally the density of 5-ht2a receptors in the frontal cortex by about 45%, whereas none of the treatments altered dopamine d2 receptor characteristics in the striatum. |
1995-03-10 |
2023-08-12 |
rat |
| B D Kretschme. Felbamate, an anti-convulsive drug, has anti-parkinsonian potential in rats. Neuroscience letters. vol 179. issue 1-2. 1995-03-09. PMID:7845605. |
the potency of felbamate, an anti-convulsive drug, to influence dopamine d1 (sch 23390) and d2 (haloperidol) receptor-mediated catalepsy (akinesia and bradykinesia) was studied in rats. |
1995-03-09 |
2023-08-12 |
rat |
| A A Megens, F H Awouters, A Schotte, T F Meert, C Dugovic, C J Niemegeers, J E Leyse. Survey on the pharmacodynamics of the new antipsychotic risperidone. Psychopharmacology. vol 114. issue 1. 1995-03-08. PMID:7531353. |
risperidone is 4-10 times less potent than haloperidol as a central d2 antagonist in rats and it differs from haloperidol by the following characteristics: predominant 5-ht2 antagonism; lsd antagonism; effects on sleep; smooth dose-response curves for d2 antagonism; synergism of combined 5-ht2/d2 antagonism; pronounced effects on amphetamine-induced oxygen consumption; increased social interaction; and pronounced effects on dopamine (da) turnover. |
1995-03-08 |
2023-08-12 |
rat |
| B M Chronwall, D M Beatty, P Sharma, S J Morri. Dopamine D2 receptors regulate in vitro melanotrope L-type Ca2+ channel activity via c-fos. Endocrinology. vol 136. issue 2. 1995-03-02. PMID:7835295. |
the dopamine d2 receptor antagonist haloperidol, which increased channel activity, could not reverse the c-fos antisense deoxynucleotide block. |
1995-03-02 |
2023-08-12 |
Not clear |
| A Imperato, M C Obinu, G Carta, M S Mascia, M A Casu, L Dazzi, G L Gess. Neuroleptics cause stimulation of dopamine D1 receptors and their desensitization after chronic treatment. European journal of pharmacology. vol 264. issue 1. 1995-02-23. PMID:7828643. |
rats were chronically treated with the dopamine d2 receptor antagonists, haloperidol and (-)-sulpiride (0.5 mg/kg and 50 mg/kg i.p., respectively, daily, for 30 days). |
1995-02-23 |
2023-08-12 |
rat |
| J L Cornish, M van den Buus. Pressor responses to electrical and chemical stimulation of the rat brain A10 dopaminergic system. Neuroscience letters. vol 176. issue 2. 1995-02-21. PMID:7530350. |
these pressor responses could be significantly attenuated by pretreatment with the dopamine d2 receptor antagonist haloperidol, but not the d1 receptor antagonist sch 23390. |
1995-02-21 |
2023-08-12 |
rat |
| D Jasso-López, R Tapi. Neurotoxic effect of intranigral injection of 1-methyl-4-phenylpyridinium on GABA-containing neurons and its relation to circling behavior. Journal of neurochemistry. vol 64. issue 2. 1995-02-21. PMID:7830073. |
the circling behavior was prevented by the dopamine carrier blocker nomifensine only during the first 2 h, whereas the dopamine receptor antagonist haloperidol was ineffective. |
1995-02-21 |
2023-08-12 |
rat |
| R R Gainetdinov, T V Grekhova, T D Sotnikova, K S Rayevsk. Dopamine D2 and D3 receptor preferring antagonists differentially affect striatal dopamine release and metabolism in conscious rats. European journal of pharmacology. vol 261. issue 3. 1995-02-09. PMID:7813556. |
classical neuroleptic drugs with high affinity for dopamine d2 receptors in comparison to d3 ones (haloperidol, thioproperazine and spiperone) administered i.p. |
1995-02-09 |
2023-08-12 |
rat |
| T Sumiyoshi, H Kido, H Sakamoto, K Urasaki, K Suzuki, N Yamaguchi, H Mori, K Shib. Time course of dopamine1,2 and serotonin2 receptor binding of antipsychotics in vivo. Pharmacology, biochemistry, and behavior. vol 49. issue 1. 1995-02-07. PMID:7816868. |
an in vivo receptor binding technique was applied to evaluate the affinities of clozapine (20 mg/kg), rmi-81582 (20 mg/kg), and haloperidol (1 mg/kg) for dopamine d1, d2 and serotonin 5-ht2 receptors in rat brain with [3h]-sch23390, [3h]-ym-09151-2, and [3h]-ketanserin as selective ligands. |
1995-02-07 |
2023-08-12 |
rat |
| J Kamei, A Saitoh, Y Iwamoto, M Funada, T Suzuki, M Misawa, H Nagase, Y Kasuy. Effects of diabetes on spontaneous locomotor activity in mice. Neuroscience letters. vol 178. issue 1. 1995-02-06. PMID:7816344. |
haloperidol and sch23390, a selective dopamine d1-receptor antagonist, significantly reduced spontaneous locomotor activity in diabetic mice, but not in non-diabetic mice. |
1995-02-06 |
2023-08-12 |
mouse |
| M Hillefors-Berglund, G Von Eule. Pharmacology of dopamine D3 receptors in the islands of Calleja of the rat using quantitative receptor autoradiography. European journal of pharmacology. vol 261. issue 1-2. 1995-01-23. PMID:8001642. |
the rank order of potency was r(-)-propylnorapomorphine > 7-oh-dpat approximately haloperidol > raclopride > dopamine > remoxipride. |
1995-01-23 |
2023-08-12 |
rat |
| M L Pucak, A A Grac. Evidence that systemically administered dopamine antagonists activate dopamine neuron firing primarily by blockade of somatodendritic autoreceptors. The Journal of pharmacology and experimental therapeutics. vol 271. issue 3. 1995-01-17. PMID:7996424. |
systemic administration of either haloperidol or of the dopamine d2-specific antagonist sulpiride caused significant increases in the firing rate of many dopamine neurons recorded both in intact rats and in rats with hemisection of the striatonigral projection. |
1995-01-17 |
2023-08-12 |
rat |
| U Schröder, H Schröder, W Augustin, B A Sabe. Haloperidol-induced behavioral supersensitivity is increased by monosialoganglioside treatment in rats without affecting spiroperidol-binding. The Journal of pharmacology and experimental therapeutics. vol 271. issue 3. 1995-01-17. PMID:7996425. |
in rats, dopamine supersensitivity was induced by haloperidol (hal) treatment for 3 weeks, either by implanted polymer matrices or by daily i.p. |
1995-01-17 |
2023-08-12 |
rat |