| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R Clement, D Griff, B Banks, C Nemeroff, P Kitabgi, G Bissett. Effects of haloperidol, quinelorane, and lithium on regional neurotensin/neuromedin N concentrations: further evidence for neurotensin/neuromedin N-dopamine interactions. Synapse (New York, N.Y.). vol 17. issue 4. 1995-01-09. PMID:7992199. |
a separate experiment examined the ability of a selective dopamine d2 receptor agonist, quinelorane, to alter nt/nmn regional concentrations after three weeks of treatment as compared to haloperidol, a d2 receptor antagonist. |
1995-01-09 |
2023-08-12 |
rat |
| G Maguire, D I Hamasak. The retinal dopamine network alters the adaptational properties of retinal ganglion cells in the cat. Journal of neurophysiology. vol 72. issue 2. 1994-12-30. PMID:7983531. |
recovery from the drug effects reflect supranormal responses after the initial response reductions and may be due to haloperidol's action on the dopamine autoreceptor. |
1994-12-30 |
2023-08-12 |
cat |
| G Mittleman, A L Rosner, C L Schau. Polydipsia and dopamine: behavioral effects of dopamine D1 and D2 receptor agonists and antagonists. The Journal of pharmacology and experimental therapeutics. vol 271. issue 2. 1994-12-29. PMID:7965779. |
the role of dopamine d1 and d2 receptors was investigated by comparing the behavioral effects of dopamine d1 agonists (skf 38393 and skf 82958) and antagonists (sch 23390 and skf 83566) to those of a dopamine d2 agonist (quinpirole) and antagonist (haloperidol) by using an animal model of excessive water consumption, drinking evoked in the sip paradigm. |
1994-12-29 |
2023-08-12 |
Not clear |
| E A Pehek, B K Yamamot. Differential effects of locally administered clozapine and haloperidol on dopamine efflux in the rat prefrontal cortex and caudate-putamen. Journal of neurochemistry. vol 63. issue 6. 1994-12-23. PMID:7964731. |
differential effects of locally administered clozapine and haloperidol on dopamine efflux in the rat prefrontal cortex and caudate-putamen. |
1994-12-23 |
2023-08-12 |
rat |
| E A Pehek, B K Yamamot. Differential effects of locally administered clozapine and haloperidol on dopamine efflux in the rat prefrontal cortex and caudate-putamen. Journal of neurochemistry. vol 63. issue 6. 1994-12-23. PMID:7964731. |
although both drugs increased extracellular dopamine levels, clozapine produced greater effects than haloperidol in the prefrontal cortex, whereas haloperidol produced greater effects in the caudate-putamen. |
1994-12-23 |
2023-08-12 |
rat |
| C Vaillancourt, A Petit, S Bélisl. D2-dopamine agonists inhibit adenosine 3':5'-cyclic monophosphate (cAMP) production in human term trophoblastic cells. Life sciences. vol 55. issue 20. 1994-12-16. PMID:7968225. |
these inhibitions were receptor specific since they were reversed by spiperone and haloperidol, two specific--dopamine antagonist, and by butaclamol (mix d2/d1-dopamine antagonists) but not by alpha- and beta-adrenergic, d1- and d4-dopaminergic, and 5-ht2-serotonergic antagonists. |
1994-12-16 |
2023-08-12 |
human |
| T Yamada, J Nakamura, M Murakami, Y Okuno, S Hosokawa, M Matsuo, H Yamad. The correlation of serum luteinizing hormone levels with the induction of Leydig cell tumors in rats by oxolinic acid. Toxicology and applied pharmacology. vol 129. issue 1. 1994-12-15. PMID:7974488. |
the increase in serum lh induced by oxolinic acid was completely blocked by the intraperitoneal injection of the dopamine antagonist haloperidol (2 mg/kg). |
1994-12-15 |
2023-08-12 |
rat |
| A N Talalaenko, I A Abramets, Stakhovskii YuV, A A Shekhovtsov, A V Chernikov, S L Shevchenk. The role of dopaminergic mechanisms on the brain in various models of anxious states. Neuroscience and behavioral physiology. vol 24. issue 3. 1994-12-12. PMID:7969883. |
haloperidol, a nonselective blocker of the d1- and d2-receptors of dopamine removes the anxiolytic effect of apomorphine, phenamine, and picrotoxin. |
1994-12-12 |
2023-08-12 |
rat |
| S O Ogren, L Rosén, K Fux. The dopamine D2 antagonist remoxipride acts in vivo on a subpopulation of dopamine D2 receptors. Neuroscience. vol 61. issue 2. 1994-12-08. PMID:7969908. |
however, remoxipride differed from both haloperidol and raclopride by showing a much reduced occupancy of dopamine d2 receptors at doses with behaviourally equipotent effects. |
1994-12-08 |
2023-08-12 |
rat |
| G G Shi, D S Wei, S F X. [Effect of agonists of opioid receptor on coronary arterial strips in porcine]. Sheng li xue bao : [Acta physiologica Sinica]. vol 46. issue 2. 1994-12-06. PMID:7973800. |
haloperidol inhibited the contraction of the strip produced by u-50488h noncompetitively, also in a dose-dependent manner, probably without involving dopamine mechanism. |
1994-12-06 |
2023-08-12 |
Not clear |
| Y Kobayashi, A Ricci, I Rossodivita, F Ament. Autoradiographic localization of dopamine D2-like receptors in the rabbit pulmonary vascular tree. Naunyn-Schmiedeberg's archives of pharmacology. vol 349. issue 6. 1994-11-29. PMID:7969505. |
the greater sensitivity to displacement by domperidone, haloperidol, (-)-sulpiride and bromocriptine than to displacement by n-propyl-norapomorphine, quinpirole or clozapine suggests that the [3h]-spiroperidol binding sites observed in extraparenchymal, large and medium-sized branches of the pulmonary artery belong, probably, to the dopamine d2 receptor subtype. |
1994-11-29 |
2023-08-12 |
rabbit |
| J Carretero, F Sanchez, M Rubio, C M Francos, J Blanco, R Vazque. In vitro and in vivo evidence for direct dopaminergic inhibition of VIP-immunoreactive pituitary cells. Neuropeptides. vol 27. issue 1. 1994-11-29. PMID:7969815. |
in order to establish whether dopamine is involved in the regulation of immunocytochemical expression of vip in pituitary cells, in vivo and in vitro studies were carried out on male rats after treatment with haloperidol and dopamine, respectively. |
1994-11-29 |
2023-08-12 |
rat |
| M Kurachi, S Yasui, R Shibata, M Murata, H Hagino, T Kurachi, Y Tanii, K Kurat. Comparative study of dopamine metabolism with local cerebral glucose utilization in rat brain following the administration of haloperidol decanoate. Biological psychiatry. vol 36. issue 2. 1994-11-28. PMID:7948443. |
comparative study of dopamine metabolism with local cerebral glucose utilization in rat brain following the administration of haloperidol decanoate. |
1994-11-28 |
2023-08-12 |
rat |
| M Kurachi, S Yasui, R Shibata, M Murata, H Hagino, T Kurachi, Y Tanii, K Kurat. Comparative study of dopamine metabolism with local cerebral glucose utilization in rat brain following the administration of haloperidol decanoate. Biological psychiatry. vol 36. issue 2. 1994-11-28. PMID:7948443. |
the effects of haloperidol decanoate on dopamine (da) metabolism in discrete regions of rat brain were investigated and compared with changes in local cerebral glucose utilization (lcgu). |
1994-11-28 |
2023-08-12 |
rat |
| B K Yamamoto, E A Pehek, H Y Meltze. Brain region effects of clozapine on amino acid and monoamine transmission. The Journal of clinical psychiatry. vol 55 Suppl B. 1994-11-28. PMID:7961581. |
the acute administration of clozapine increased dopamine and glutamate in the medial prefrontal cortex and produced a greater increase, compared with haloperidol, in gaba (gamma-aminobutyric acid) efflux within the ventral pallidum. |
1994-11-28 |
2023-08-12 |
rat |
| K Nomura, N Maeda, T Yoshino, I Yamaguch. A mechanism of 5-HT3 receptor mediation is involved etiologically in the psychological stress lesion the stomach of the mouse. The Journal of pharmacology and experimental therapeutics. vol 271. issue 1. 1994-11-25. PMID:7965702. |
in contrast, a peripherally acting 5-ht3 antagonist, m-840 ([[3-(1-methyl-1h-indol-3-yl)-1,2,4-oxadiazol-5- yl]-methyl]trimethyl-ammonium iodide), dopamine acting compounds, haloperidol and fr64822 [n-(4-pyridylcarbamoyl)amino-1,2,3,6- tetrahydropyridine), and antisecretory drugs, atropine and famotidine, minimally affected the lesion formation. |
1994-11-25 |
2023-08-12 |
mouse |
| K M Merchant, D J Dobie, F M Filloux, M Totzke, M Aravagiri, D M Dors. Effects of chronic haloperidol and clozapine treatment on neurotensin and c-fos mRNA in rat neostriatal subregions. The Journal of pharmacology and experimental therapeutics. vol 271. issue 1. 1994-11-25. PMID:7965747. |
interestingly, dopamine d2 receptor binding using [125i]iodosulpride nearly doubled in all regions of the striatum after chronic haloperidol but not clozapine. |
1994-11-25 |
2023-08-12 |
rat |
| M Yamada, T Nishigami, K Nakasho, Y Nishimoto, H Miyaj. Relationship between sigma-like site and progesterone-binding site of adult male rat liver microsomes. Hepatology (Baltimore, Md.). vol 20. issue 5. 1994-11-23. PMID:7927262. |
as a result, we demonstrated that adult male rat liver microsomes, especially smooth endoplasmic reticulum, possessed a saturable haloperidol-binding site closely resembling the sigma site, with a high affinity (kd 1.0 +/- 0.3 nmol/l) and high capacity (bmax 9.3 +/- 1.5 pmol/mg protein) and with the rank order of affinity of the ligands: haloperidol > reduced haloperidol > clorgyline > ifenprodil > 1,3-di(2-tolyl)guanidine, (-)-butaclamol > gbr-12909 > skf-525a > progesterone > 5 alpha-dihydrotestosterone > r(+)-3- (hydroxyphenyl)-n-propylpiperidine > testosterone >> corticosteroids, estradiol-17 beta, cholesterol and neuroactive compounds displaying high affinities for other neurotransmitter receptors such as dopamine d2, serotonin (5-ht1a and 5-ht2) and alpha 1-adrenergic and gabaa receptors. |
1994-11-23 |
2023-08-12 |
rat |
| E Guenther, V Wilsch, E Zrenne. Inhibitory action of haloperidol, spiperone and SCH23390 on calcium currents in rat retinal ganglion cells. Neuroreport. vol 5. issue 11. 1994-11-22. PMID:7919203. |
we report here that, in the absence of dopamine, application of the receptor antagonists haloperidol, spiperone and sch23390 reduced calcium influx between 8% and 77%. |
1994-11-22 |
2023-08-12 |
rat |
| L J Cohe. Risperidone. Pharmacotherapy. vol 14. issue 3. 1994-11-21. PMID:7524043. |
its affinity for serotonin receptors is approximately 200 times greater than that of haloperidol, and its dopamine antagonistic potency is comparable to that of haloperidol. |
1994-11-21 |
2023-08-12 |
Not clear |