| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Jaber, F Tison, M C Fournier, B Bloc. Differential influence of haloperidol and sulpiride on dopamine receptors and peptide mRNA levels in the rat striatum and pituitary. Brain research. Molecular brain research. vol 23. issue 1-2. 1994-08-08. PMID:7518029. |
our results demonstrate that the effect of a chronic haloperidol treatment on striatal dopamine receptors and neuropeptide mrna levels is different to that of sulpiride, whereas it is similar on pituitary hormones mrna levels. |
1994-08-08 |
2023-08-12 |
rat |
| T J De Vries, A J Jonker, P Voorn, A H Mulder, A N Schoffelmee. Adaptive changes in rat striatal preproenkephalin expression and dopamine-opioid interactions upon chronic haloperidol treatment during different developmental stages. Brain research. Developmental brain research. vol 78. issue 2. 1994-08-05. PMID:7913003. |
this study was designed to evaluate the effects of a chronic treatment with the classical neuroleptic drug haloperidol on the preproenkephalin (ppenk) mrna synthesis and its consequences for opioid and dopamine (da) receptor-regulated adenylate cyclase in the developing and adult rat striatum. |
1994-08-05 |
2023-08-12 |
rat |
| T Skarsfeld. Comparison of short-term administration of sertindole, clozapine and haloperidol on the inactivation of midbrain dopamine neurons in the rat. European journal of pharmacology. vol 254. issue 3. 1994-07-25. PMID:7912200. |
comparison of short-term administration of sertindole, clozapine and haloperidol on the inactivation of midbrain dopamine neurons in the rat. |
1994-07-25 |
2023-08-12 |
rat |
| T Skarsfeld. Comparison of short-term administration of sertindole, clozapine and haloperidol on the inactivation of midbrain dopamine neurons in the rat. European journal of pharmacology. vol 254. issue 3. 1994-07-25. PMID:7912200. |
the present study describes the effect of sertindole, clozapine and haloperidol on the number of spontaneously active dopamine neurons in ventral tegmental area and substantia nigra pars compacta after daily oral treatment for 1, 2 or 3 weeks. |
1994-07-25 |
2023-08-12 |
rat |
| T Skarsfeld. Comparison of short-term administration of sertindole, clozapine and haloperidol on the inactivation of midbrain dopamine neurons in the rat. European journal of pharmacology. vol 254. issue 3. 1994-07-25. PMID:7912200. |
in general, daily administration of high dosages (sertindole: 2.8 mumol/kg/day, clozapine: 60 mumol/kg/day, haloperidol: 0.43 mumol/kg/day) induced no statistically significant decrease in the number of active dopamine neurons within the first 2 weeks of treatment. |
1994-07-25 |
2023-08-12 |
rat |
| A M Gonzalez, D Walther, A Pazos, G R Uh. Synaptic vesicular monoamine transporter expression: distribution and pharmacologic profile. Brain research. Molecular brain research. vol 22. issue 1-4. 1994-07-25. PMID:7912402. |
cos cell hsvmt expression yielded nanomolar affinities for tetrabenazine and reserpine, micromolar affinities for haloperidol, gbr12909, serotonin, mazindol, nomifensin and d-amphetamine, while dopamine, epinephrine, norepinephrine and histamine each displayed millimolar affinities. |
1994-07-25 |
2023-08-12 |
human |
| D Nouel, J Costenti. Locomotor effects of [D-Trp11]neurotensin and dopamine transmission in rats. European journal of pharmacology. vol 254. issue 3. 1994-07-25. PMID:8013561. |
this latter locomotor stimulant effect was suppressed by the dopamine antagonist, haloperidol (50 micrograms/kg, i.p.). |
1994-07-25 |
2023-08-12 |
rat |
| J J Soghomonia. Differential regulation of glutamate decarboxylase and preproenkephalin mRNA levels in the rat striatum. Brain research. vol 640. issue 1-2. 1994-07-21. PMID:8004444. |
the mrna levels encoding for the enzyme glutamate decarboxylase (gad67) and the peptide enkephalin were measured in the striatum of adult and 15 day-old rats by in situ hybridization histochemistry and radioautography after neonatal injections of 6-hydroxydopamine or after acute pharmacological blockade of dopamine receptors with haloperidol or sulpiride. |
1994-07-21 |
2023-08-12 |
rat |
| J J Soghomonia. Differential regulation of glutamate decarboxylase and preproenkephalin mRNA levels in the rat striatum. Brain research. vol 640. issue 1-2. 1994-07-21. PMID:8004444. |
in adult rats injected as neonates with 6-hydroxydopamine or treated with the d1/d2 dopamine receptors antagonist, haloperidol, an increase in preproenkephalin and gad67 mrna levels was measured in the striatum. |
1994-07-21 |
2023-08-12 |
rat |
| G A Higgins, N Joharchi, Y Wang, W A Corrigall, E M Seller. The CCKA receptor antagonist devazepide does not modify opioid self-administration or drug discrimination: comparison with the dopamine antagonist haloperidol. Brain research. vol 640. issue 1-2. 1994-07-21. PMID:8004452. |
the ccka receptor antagonist devazepide does not modify opioid self-administration or drug discrimination: comparison with the dopamine antagonist haloperidol. |
1994-07-21 |
2023-08-12 |
rat |
| G A Higgins, N Joharchi, Y Wang, W A Corrigall, E M Seller. The CCKA receptor antagonist devazepide does not modify opioid self-administration or drug discrimination: comparison with the dopamine antagonist haloperidol. Brain research. vol 640. issue 1-2. 1994-07-21. PMID:8004452. |
because of evidence implicating an interaction between accumbens cck and dopamine (da) systems and evidence suggesting an apparent differential involvement of da in opioid place conditioning, self-administration and drug discrimination behaviour, the effect of the da antagonist haloperidol was examined in the latter two paradigms. |
1994-07-21 |
2023-08-12 |
rat |
| O Stork, T Hashimoto, K Obat. Increase of tyrosine hydroxylase and its mRNA in the rat substantia nigra pars reticulata by diazepam and picrotoxin. Neuroscience research. vol 19. issue 1. 1994-07-20. PMID:7911985. |
co-administration of diazepam with a dopamine antagonist haloperidol did not further elevate, but rather, reduced haloperidol-induced increases in th labeling. |
1994-07-20 |
2023-08-12 |
rat |
| R E Steinpreis, J D Sokolowski, A Papanikolaou, J D Salamon. The effects of haloperidol and clozapine on PCP- and amphetamine-induced suppression of social behavior in the rat. Pharmacology, biochemistry, and behavior. vol 47. issue 3. 1994-07-11. PMID:8208777. |
the purpose of the present study was to determine the effects of the dopamine antagonists clozapine and haloperidol on pcp- and amphetamine-induced changes in rat social behavior. |
1994-07-11 |
2023-08-12 |
rat |
| O Shirakawa, C A Tamming. Basal ganglia GABAA and dopamine D1 binding site correlates of haloperidol-induced oral dyskinesias in rat. Experimental neurology. vol 127. issue 1. 1994-07-07. PMID:8200438. |
in an attempt to understand the neurochemical mechanism of these rat dyskinesias, we measured regional dopamine d1, d2, and gabaa binding density in rats with and without vcms after chronic haloperidol treatment and in untreated controls using in vitro receptor autoradiography and correlated the binding changes with the dyskinetic behavior. |
1994-07-07 |
2023-08-12 |
rat |
| O Shirakawa, C A Tamming. Basal ganglia GABAA and dopamine D1 binding site correlates of haloperidol-induced oral dyskinesias in rat. Experimental neurology. vol 127. issue 1. 1994-07-07. PMID:8200438. |
chronic haloperidol treatment produced an overall increase in dopamine d2 family receptor binding in the caudate putamen and in nucleus accumbens in both groups of treated rats, those with and without vcms. |
1994-07-07 |
2023-08-12 |
rat |
| O Shirakawa, C A Tamming. Basal ganglia GABAA and dopamine D1 binding site correlates of haloperidol-induced oral dyskinesias in rat. Experimental neurology. vol 127. issue 1. 1994-07-07. PMID:8200438. |
perhaps the release of dopamine from dendrites of the local da-containing neurons might be variably enhanced with ongoing haloperidol treatment. |
1994-07-07 |
2023-08-12 |
rat |
| M Kurachi, S Yasui, R Shibata, M Murata, H Hagino, Y Tanii, K Kurat. Changes in local cerebral glucose utilization and dopamine metabolism in the rat brain following acute administration of haloperidol. The Japanese journal of psychiatry and neurology. vol 47. issue 4. 1994-07-07. PMID:8201804. |
changes in local cerebral glucose utilization and dopamine metabolism in the rat brain following acute administration of haloperidol. |
1994-07-07 |
2023-08-12 |
rat |
| M Kurachi, S Yasui, R Shibata, M Murata, H Hagino, Y Tanii, K Kurat. Changes in local cerebral glucose utilization and dopamine metabolism in the rat brain following acute administration of haloperidol. The Japanese journal of psychiatry and neurology. vol 47. issue 4. 1994-07-07. PMID:8201804. |
the effects of acute administration of haloperidol on local cerebral glucose utilization (lcgu) in 26 discrete regions of the rat brain were examined by the quantitative autoradiographic [14c] 2-deoxy-d-glucose technique and compared with the changes in dopamine (da) metabolism in 13 brain regions examined by a high performance liquid chromatographic assay. |
1994-07-07 |
2023-08-12 |
rat |
| J T Cheng, S S Chang, F L Hs. Antihypertensive action of geraniin in rats. The Journal of pharmacy and pharmacology. vol 46. issue 1. 1994-07-06. PMID:7911162. |
failure of the antagonists, idazoxan and yohimbine for alpha 2-adrenoceptors as well as haloperidol and domperidone for dopamine receptors, to reverse the antihypertensive actions of geraniin ruled out the possible mediation of these receptors. |
1994-07-06 |
2023-08-12 |
rat |
| C J Dong, F S Werbli. Dopamine modulation of GABAC receptor function in an isolated retinal neuron. Journal of neurophysiology. vol 71. issue 3. 1994-07-06. PMID:8201417. |
this effect of dopamine was mimicked by the d1 agonist skf38393 (25 microm) and an adenylyl cyclase activator forskolin (20 microm) but blocked by the dopamine antagonist haloperidol (30 microm). |
1994-07-06 |
2023-08-12 |
Not clear |