| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S B Freedman, S Patel, R Marwood, F Emms, G R Seabrook, M R Knowles, G McAlliste. Expression and pharmacological characterization of the human D3 dopamine receptor. The Journal of pharmacology and experimental therapeutics. vol 268. issue 1. 1994-03-10. PMID:8301582. |
only limited binding selectivity was observed for known dopamine d2 receptor antagonists from a variety of chemical classes, which included haloperidol, chlorpromazine, sulpiride, pimozide and cis flupenthixol. |
1994-03-10 |
2023-08-12 |
human |
| N R Swerdlow, D L Braff, N Taaid, M A Geye. Assessing the validity of an animal model of deficient sensorimotor gating in schizophrenic patients. Archives of general psychiatry. vol 51. issue 2. 1994-03-03. PMID:8297213. |
construct validity was supported: ppi was disrupted in rats when dopamine was infused into the nucleus accumbens; this effect was blocked by haloperidol. |
1994-03-03 |
2023-08-12 |
rat |
| A Verma, S K Kulkarn. Differential role of dopamine receptor subtypes in thermoregulation and stereotypic behavior in naive and reserpinized rats. Archives internationales de pharmacodynamie et de therapie. vol 324. 1994-03-02. PMID:7905255. |
in naive rats, the d2 dopamine agonist b-ht920 (0.25-1 mg/kg) produced hypothermia, an effect sensitive to blockade by the d1/d2 antagonist haloperidol (0.5 mg/kg) and to potentiation by the d1 agonist skf38393 (5 mg/kg). |
1994-03-02 |
2023-08-12 |
rat |
| K Svensson, E Eriksson, A Carlsso. Partial dopamine receptor agonists reverse behavioral, biochemical and neuroendocrine effects of neuroleptics in the rat: potential treatment of extrapyramidal side effects. Neuropharmacology. vol 32. issue 10. 1994-02-25. PMID:7905192. |
the partial da receptor agonist preclamol, (-)-3-ppp (50-200 mumol/kg, s.c.) partially reversed the catalepsy induced by the dopamine (da) receptor antagonists haloperidol (5.3 mumol/kg, i.p.) |
1994-02-25 |
2023-08-12 |
rat |
| T Y Lo. Effects of dopamine on the gastrointestinal tract of chicks. The Journal of pharmacy and pharmacology. vol 45. issue 10. 1994-02-24. PMID:7904629. |
contraction of the lower oesophagus induced by dopamine was abolished by lysergic acid diethylamide and was antagonized by moderate concentrations of haloperidol or pimozide. |
1994-02-24 |
2023-08-12 |
Not clear |
| A F Yakimovskii, I V Karpov. The influence of chronic activation and blockade of the dopamine- and enkephalinergic systems of the neostriatum on conditioned reflex behavior and dopamine metabolism in the rat nigrostriatal system. Neuroscience and behavioral physiology. vol 23. issue 6. 1994-02-24. PMID:8290027. |
injections of phenamine and haloperidol were accompanied by a decrease in the content of dopamine in the striatum and an increase in the level of dopac; the injections of enkephalin and naloxone induced changes of the reverse order. |
1994-02-24 |
2023-08-12 |
rat |
| F Naarendorp, P F Hitchock, P A Sievin. Dopaminergic modulation of rod pathway signals does not affect the scotopic ERG of cat at dark-adapted threshold. Journal of neurophysiology. vol 70. issue 4. 1994-02-15. PMID:8283223. |
both 6-ohda pretreatment and application of the dopamine antagonist, haloperidol, increased the str amplitudes, but only for stimuli beginning 2 log units above threshold; pii amplitude also was increased. |
1994-02-15 |
2023-08-12 |
cat |
| R L Hakan, C Hart, C Ey. Specific neurophysiological effects of systemic nicotine on neurons in the nucleus accumbens. Synapse (New York, N.Y.). vol 15. issue 3. 1994-02-09. PMID:7904087. |
in other experiments, nicotine-induced inhibition of nas fimbria-driven units was followed by haloperidol (0.5 mg/kg, s.c.), in attempts to reveal the possible role of dopamine in these effects. |
1994-02-09 |
2023-08-12 |
rat |
| O Shirakawa, K Maeda, K Saka. Dysregulation of striato-nigral GABAergic pathway by chronic haloperidol treatment: the role of dopamine D1 receptor in the substantia nigra pars reticulata on the development of tardive dyskinesia. The Japanese journal of psychiatry and neurology. vol 47. issue 2. 1994-01-31. PMID:8271625. |
dysregulation of striato-nigral gabaergic pathway by chronic haloperidol treatment: the role of dopamine d1 receptor in the substantia nigra pars reticulata on the development of tardive dyskinesia. |
1994-01-31 |
2023-08-12 |
Not clear |
| P R Sanberg, D F Emerich, M M el-Etri, M T Shipley, M D Zanol, D W Cahill, A B Norma. Nicotine potentiation of haloperidol-induced catalepsy: striatal mechanisms. Pharmacology, biochemistry, and behavior. vol 46. issue 2. 1994-01-27. PMID:8265684. |
a second experiment examined whether the ability of nicotine to potentiate haloperidol-induced catalepsy was associated with a potentiation of dopamine turnover following haloperidol. |
1994-01-27 |
2023-08-12 |
rat |
| P R Sanberg, D F Emerich, M M el-Etri, M T Shipley, M D Zanol, D W Cahill, A B Norma. Nicotine potentiation of haloperidol-induced catalepsy: striatal mechanisms. Pharmacology, biochemistry, and behavior. vol 46. issue 2. 1994-01-27. PMID:8265684. |
nicotine alone produced a mild increase in dopamine turnover relative to saline treated controls while haloperidol produced a marked increase in dopamine turnover relative to saline- and nicotine-treated controls. |
1994-01-27 |
2023-08-12 |
rat |
| P R Sanberg, D F Emerich, M M el-Etri, M T Shipley, M D Zanol, D W Cahill, A B Norma. Nicotine potentiation of haloperidol-induced catalepsy: striatal mechanisms. Pharmacology, biochemistry, and behavior. vol 46. issue 2. 1994-01-27. PMID:8265684. |
however, the combined administration of haloperidol and nicotine did not further elevate dopamine turnover over that observed following haloperidol alone. |
1994-01-27 |
2023-08-12 |
rat |
| P R Sanberg, D F Emerich, M M el-Etri, M T Shipley, M D Zanol, D W Cahill, A B Norma. Nicotine potentiation of haloperidol-induced catalepsy: striatal mechanisms. Pharmacology, biochemistry, and behavior. vol 46. issue 2. 1994-01-27. PMID:8265684. |
the results indicated that: 1) nicotine could not potentiate haloperidol-induced catalepsy without an intact striatum and 2) the behavioral effect of nicotine and haloperidol cotreatment was not due to any change in dopamine turnover. |
1994-01-27 |
2023-08-12 |
rat |
| M Watanabe, S Ohtakeno, H Watanabe, G Mamiya, N Ichinowatar. Effects of long-term treatment of haloperidol on D2 dopamine receptors in various areas of rat brain. Yakubutsu, seishin, kodo = Japanese journal of psychopharmacology. vol 13. issue 5. 1994-01-26. PMID:8266741. |
effects of long-term treatment of haloperidol on d2 dopamine receptors in various areas of rat brain. |
1994-01-26 |
2023-08-12 |
rat |
| M Watanabe, S Ohtakeno, H Watanabe, G Mamiya, N Ichinowatar. Effects of long-term treatment of haloperidol on D2 dopamine receptors in various areas of rat brain. Yakubutsu, seishin, kodo = Japanese journal of psychopharmacology. vol 13. issue 5. 1994-01-26. PMID:8266741. |
effects of long-term treatment of haloperidol on d2 dopamine receptors in various brain areas were examined. |
1994-01-26 |
2023-08-12 |
rat |
| M Watanabe, S Ohtakeno, H Watanabe, G Mamiya, N Ichinowatar. Effects of long-term treatment of haloperidol on D2 dopamine receptors in various areas of rat brain. Yakubutsu, seishin, kodo = Japanese journal of psychopharmacology. vol 13. issue 5. 1994-01-26. PMID:8266741. |
haloperidol treatment was found to increase the number of binding sites of d2 dopamine receptors in striatum, olfactory tubercle, hypothalamus and anterior pituitary, while bmax of d2 receptors in hippocampus was decreased by haloperidol treatment. |
1994-01-26 |
2023-08-12 |
rat |
| K K Tangri, S K Gupta, S Vrat, M Husai. A study of effects of putative neurotransmitters injected into the lateral cerebral ventricle of man. Progress in neuro-psychopharmacology & biological psychiatry. vol 17. issue 5. 1994-01-13. PMID:7902993. |
opposite cardiovascular and thermal effects were observed with blockade of alpha 1-, beta-and dopamine receptors with prazosin, propranolol and haloperidol respectively. |
1994-01-13 |
2023-08-12 |
human |
| N Waters, S Lagerkvist, L Löfberg, M Piercey, A Carlsso. The dopamine D3 receptor and autoreceptor preferring antagonists (+)-AJ76 and (+)-UH232; a microdialysis study. European journal of pharmacology. vol 242. issue 2. 1994-01-13. PMID:8253112. |
the in vivo neurochemical profiles of haloperidol, raclopride and the dopamine d3 and autoreceptor preferring dopamine receptor antagonists (+)-uh232 and (+)-aj76 on dopamine release and metabolism in the dorsal striatum and in the nucleus accumbens are described. |
1994-01-13 |
2023-08-12 |
Not clear |
| N Waters, S Lagerkvist, L Löfberg, M Piercey, A Carlsso. The dopamine D3 receptor and autoreceptor preferring antagonists (+)-AJ76 and (+)-UH232; a microdialysis study. European journal of pharmacology. vol 242. issue 2. 1994-01-13. PMID:8253112. |
it is shown that both (+)-uh232 and especially (+)-aj76 have different effects on brain dialysate dopamine and 3,4-dihydroxyphenylacetic acid (dopac) as compared to haloperidol or raclopride. |
1994-01-13 |
2023-08-12 |
Not clear |
| J C Jaen, B W Caprathe, T A Pugsley, L D Wise, H Akunn. Evaluation of the effects of the enantiomers of reduced haloperidol, azaperol, and related 4-amino-1-arylbutanols on dopamine and sigma receptors. Journal of medicinal chemistry. vol 36. issue 24. 1994-01-11. PMID:7902870. |
evaluation of the effects of the enantiomers of reduced haloperidol, azaperol, and related 4-amino-1-arylbutanols on dopamine and sigma receptors. |
1994-01-11 |
2023-08-12 |
rat |