Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
S Yamada, T Takaki, H Yokoo, M Tanak. Differential effects of dopamine antagonists on evoked dopamine release from slices of striatum and nucleus accumbens in rats. The Journal of pharmacy and pharmacology. vol 47. issue 3. 1995-08-09. PMID:7602493. |
these findings indicate that, in terms of dopamine transmission, (-)-sulpiride and clozapine, but not haloperidol, predominantly affect the nucleus accumbens rather than the striatum. |
1995-08-09 |
2023-08-12 |
rat |
b' L Gim\\xc3\\xa9nez-Llort, E Mart\\xc3\\xadnez, S Ferr\\xc3\\xa. Dopamine-independent and adenosine-dependent mechanisms involved in the effects of N-methyl-D-aspartate on motor activity in mice. European journal of pharmacology. vol 275. issue 2. 1995-08-03. PMID:7796852.' |
in reserpinized mice, the non-selective dopamine antagonist, haloperidol (0.5 mg/kg s.c.) antagonized the motor activation induced by apomorphine (0.1 mg/kg s.c.) and the induced by theophylline (10 mg/kg i.p.) |
1995-08-03 |
2023-08-12 |
mouse |
E H Shen, J C Crabbe, T J Phillip. Dopamine antagonist effects on locomotor activity in naive and ethanol-treated FAST and SLOW selected lines of mice. Psychopharmacology. vol 118. issue 1. 1995-07-28. PMID:7597119. |
the ethanol-stimulated activity of fast-1 and fast-2 mice was decreased by administration of the dopamine antagonists, haloperidol and raclopride, at doses that had no effect on basal locomotor activity. |
1995-07-28 |
2023-08-12 |
mouse |
M Kurachi, R Shibata, M Murata, Y Tani. Parallel development of dopamine metabolism tolerance in the rat prefrontal cortex, caudate-putamen, and amygdala following haloperidol decanoate administration. Biological psychiatry. vol 37. issue 7. 1995-07-27. PMID:7786966. |
parallel development of dopamine metabolism tolerance in the rat prefrontal cortex, caudate-putamen, and amygdala following haloperidol decanoate administration. |
1995-07-27 |
2023-08-12 |
rat |
K Nomura, N Maeda, T Yoshino, I Yamaguch. Different mechanisms mediated by dopamine D1 and D2 receptors are involved etiologically in activity-stress gastric lesion of the rat. The Journal of pharmacology and experimental therapeutics. vol 273. issue 3. 1995-07-21. PMID:7791069. |
daily treatment with centrally acting dopamine antagonists, sch23390 [(r)-(+)-8-chloro-2,3,4,5-tetrahydro-3-methyl-5-phenyl-1h-3- benzazepin-7-ol] (0.1-10 mg/kg), haloperidol (0.1-10 mg/kg), sulpiride (32-320 mg/kg), clozapine (1-100 mg/kg) and metoclopramide (1-100 mg/kg) suppressed the lesion formation: id50 values were 0.9, 0.4, 53, 8.9 and 60 mg/kg, respectively. |
1995-07-21 |
2023-08-12 |
rat |
K Nomura, N Maeda, T Yoshino, I Yamaguch. Different mechanisms mediated by dopamine D1 and D2 receptors are involved etiologically in activity-stress gastric lesion of the rat. The Journal of pharmacology and experimental therapeutics. vol 273. issue 3. 1995-07-21. PMID:7791069. |
the excessive running activity was reversed dose-dependently by treatment with haloperidol, a specific dopamine d2 antagonist, but not by sch23390, a specific dopamine d1 antagonist. |
1995-07-21 |
2023-08-12 |
rat |
S B Caine, M A Geyer, N R Swerdlo. Effects of D3/D2 dopamine receptor agonists and antagonists on prepulse inhibition of acoustic startle in the rat. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 12. issue 2. 1995-07-20. PMID:7779242. |
given the 100-fold higher affinity of haloperidol relative to uh 232 for d2 receptors, and equal relative affinities of these antagonists for d3 receptors, these data are consistent with previous studies suggesting that dopamine agonists may modulate ppi in the rat through the d2 subtype of dopamine receptors. |
1995-07-20 |
2023-08-12 |
rat |
O Schoots, P Seeman, H C Guan, A D Paterson, H H Van To. Long-term haloperidol elevates dopamine D4 receptors by 2-fold in rats. European journal of pharmacology. vol 289. issue 1. 1995-07-14. PMID:7781713. |
long-term haloperidol elevates dopamine d4 receptors by 2-fold in rats. |
1995-07-14 |
2023-08-12 |
rat |
O Schoots, P Seeman, H C Guan, A D Paterson, H H Van To. Long-term haloperidol elevates dopamine D4 receptors by 2-fold in rats. European journal of pharmacology. vol 289. issue 1. 1995-07-14. PMID:7781713. |
we here describe the effect of a one-month treatment with haloperidol on dopamine d4 receptor mrna and protein levels in rat striatum. |
1995-07-14 |
2023-08-12 |
rat |
J Koistinaho, S M Saga. Light-induced c-fos expression in amacrine cells in the rabbit retina. Brain research. Molecular brain research. vol 29. issue 1. 1995-07-06. PMID:7770001. |
nicotine, kainic acid, nmda and sch 38393, a dopamine d1 receptor agonist, induced fos immunostaining in the inner nuclear and ganglion cell layers, but administration of the corresponding receptor blockers mecamylamine, kynuretic acid, mk-801, haloperidol and sch 23990 did not prevent light-induced fos expression. |
1995-07-06 |
2023-08-12 |
rabbit |
P de Koning, M H de Vrie. A comparison of the neuro-endocrinological and temperature effects of DU 29894, flesinoxan, sulpiride and haloperidol in normal volunteers. British journal of clinical pharmacology. vol 39. issue 1. 1995-06-23. PMID:7756102. |
with a separation of 1 week between sessions, volunteers received randomly one oral dose of each of the following compounds: 3 or 10 mg of the dopamine (da2) receptor antagonist and serotonin (5ht1a) agonist du 29894, 1 mg flesinoxan, 400 mg sulpiride, 3 mg haloperidol or placebo. |
1995-06-23 |
2023-08-12 |
human |
J S Kreeger, Yukhananov RYu, A A Larso. Altered N-methyl-D-aspartate (NMDA) activity in the mouse spinal cord following morphine is mediated by sigma activity. Brain research. vol 672. issue 1-2. 1995-06-22. PMID:7749756. |
this excitatory effect of morphine on nmda-induced behaviors, unmasked in the presence of naloxone was prevented but not reversed by haloperidol, a sigma ligand and dopamine antagonist, but not by an equivalent dose of spiperone, a dopamine antagonist. |
1995-06-22 |
2023-08-12 |
mouse |
G S Robertson, M Jia. D1 and D2 dopamine receptors differentially increase Fos-like immunoreactivity in accumbal projections to the ventral pallidum and midbrain. Neuroscience. vol 64. issue 4. 1995-06-21. PMID:7753373. |
in contrast, neuroleptics such as haloperidol and raclopride increase fos-like immunoreactivity by blocking striatal d2 dopamine receptors. |
1995-06-21 |
2023-08-12 |
Not clear |
S Koizumi, M Ikeda, K Nakazawa, K Inoue, K Ito, K Inou. Inhibition by haloperidol of adenosine 5'-triphosphate-evoked responses in rat pheochromocytoma cells. Biochemical and biophysical research communications. vol 210. issue 2. 1995-06-21. PMID:7755642. |
these results suggest that haloperidol inhibits the atp-receptor/channel, leading to the attenuation of the atp-evoked increase in [ca]i. mechanisms involving dopamine receptors may not contribute to the inhibition by haloperidol. |
1995-06-21 |
2023-08-12 |
rat |
S Yamada, T Takaki, H Yokoo, M Tanak. [Inhibitory effect of haloperidol on evoked dopamine release from striatal slices of the rat]. Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology. vol 15. issue 1. 1995-06-20. PMID:7750016. |
[inhibitory effect of haloperidol on evoked dopamine release from striatal slices of the rat]. |
1995-06-20 |
2023-08-12 |
rat |
K J Feasey-Truger, C D Earl, C Alzheimer, G ten Bruggencat. Stimulus-evoked dopamine overflow in the rat nucleus accumbens is decreased following chronic haloperidol administration: an in vivo voltammetric study. Neuroscience letters. vol 183. issue 1-2. 1995-06-14. PMID:7746495. |
stimulus-evoked dopamine overflow in the rat nucleus accumbens is decreased following chronic haloperidol administration: an in vivo voltammetric study. |
1995-06-14 |
2023-08-12 |
rat |
K J Feasey-Truger, C D Earl, C Alzheimer, G ten Bruggencat. Stimulus-evoked dopamine overflow in the rat nucleus accumbens is decreased following chronic haloperidol administration: an in vivo voltammetric study. Neuroscience letters. vol 183. issue 1-2. 1995-06-14. PMID:7746495. |
fast cyclic voltammetry was used to investigate the effects of chronic haloperidol (hal) treatment on electrically evoked dopamine (da) overflow in the nucleus accumbens of the anaesthetized rat in vivo. |
1995-06-14 |
2023-08-12 |
rat |
J D Salamone, M S Cousins, S Buche. Anhedonia or anergia? Effects of haloperidol and nucleus accumbens dopamine depletion on instrumental response selection in a T-maze cost/benefit procedure. Behavioural brain research. vol 65. issue 2. 1995-05-25. PMID:7718155. |
effects of haloperidol and nucleus accumbens dopamine depletion on instrumental response selection in a t-maze cost/benefit procedure. |
1995-05-25 |
2023-08-12 |
rat |
G W Lambert, M Horne, V Kalff, M J Kelly, A G Turner, H S Cox, G L Jennings, M D Esle. Central nervous system noradrenergic and dopaminergic turnover in response to acute neuroleptic challenge. Life sciences. vol 56. issue 19. 1995-05-25. PMID:7723582. |
central nervous system neuronal activity was assessed by measuring the plasma concentration and overflow from the brain of dopamine, norepinephrine, and their lipophilic and acidic metabolites after acute intravenous administration of haloperidol. |
1995-05-25 |
2023-08-12 |
human |
b' P Brun, R Steinberg, G Le Fur, P Soubri\\xc3\\xa. Blockade of neurotensin receptor by SR 48692 potentiates the facilitatory effect of haloperidol on the evoked in vivo dopamine release in the rat nucleus accumbens. Journal of neurochemistry. vol 64. issue 5. 1995-05-23. PMID:7722490.' |
blockade of neurotensin receptor by sr 48692 potentiates the facilitatory effect of haloperidol on the evoked in vivo dopamine release in the rat nucleus accumbens. |
1995-05-23 |
2023-08-12 |
rat |