| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C M Villalón, E Ramírez-San Juan, C Castillo, E Castillo, F J López-Muñoz, J A Terró. Pharmacological profile of the receptors that mediate external carotid vasoconstriction by 5-HT in vagosympathectomized dogs. British journal of pharmacology. vol 116. issue 6. 1996-04-04. PMID:8591004. |
the above vasoconstrictor effects of 5-ht remained unaltered after administration of phentolamine, propranolol, atropine, hexamethonium, brompheniramine, cimetidine and haloperidol, thus excluding the involvement of alpha- and beta-adrenoceptors, muscarinic, nicotinic, histamine and dopamine receptors. |
1996-04-04 |
2023-08-12 |
Not clear |
| T A Jenkins, S Y Chai, D W Howells, F A Mendelsoh. Intrastriatal angiotensin II induces turning behaviour in 6-hydroxydopamine lesioned rats. Brain research. vol 691. issue 1-2. 1996-03-25. PMID:8590055. |
preadministration of the dopamine antagonist, haloperidol (2 mg/kg i.p.) |
1996-03-25 |
2023-08-12 |
rat |
| J Hennig, U Rzepka, B Mai, P Nette. Suppression of HPA-axis activity by haloperidol after experimentally induced heat stress. Progress in neuro-psychopharmacology & biological psychiatry. vol 19. issue 4. 1996-03-22. PMID:8588059. |
the findings of this study suggest that d2-receptors of tuberoinfundibular neurons are blocked by haloperidol which suppresses the dopamine mediated release of vasopressin induced by dehydration and the subsequent stimulation of crh. |
1996-03-22 |
2023-08-12 |
human |
| J Fang, P H Y. Effect of haloperidol and its metabolites on dopamine and noradrenaline uptake in rat brain slices. Psychopharmacology. vol 121. issue 3. 1996-03-19. PMID:8584621. |
effect of haloperidol and its metabolites on dopamine and noradrenaline uptake in rat brain slices. |
1996-03-19 |
2023-08-12 |
rat |
| J Fang, P H Y. Effect of haloperidol and its metabolites on dopamine and noradrenaline uptake in rat brain slices. Psychopharmacology. vol 121. issue 3. 1996-03-19. PMID:8584621. |
the effects of haloperidol and its metabolites on dopamine (da) and noradrenaline (na) uptake were investigated. |
1996-03-19 |
2023-08-12 |
rat |
| Y Ohno, T Ishibashi, K Okada, K Ishida, M Nakamur. Effects of subchronic treatments with SM-9018, a novel 5-HT2 and D2 antagonist, on dopamine and 5-HT receptors in rats. Progress in neuro-psychopharmacology & biological psychiatry. vol 19. issue 6. 1996-03-19. PMID:8584685. |
receptor binding and behavioral studies were performed to compare the effects of subchronic treatments with sm-9018, a novel 5-ht2 and d2 antagonist, and with haloperidol (hal) on dopamine and 5-ht receptors in rats. |
1996-03-19 |
2023-08-12 |
rat |
| B L Murphy, A F Arnsten, P S Goldman-Rakic, R H Rot. Increased dopamine turnover in the prefrontal cortex impairs spatial working memory performance in rats and monkeys. Proceedings of the National Academy of Sciences of the United States of America. vol 93. issue 3. 1996-03-14. PMID:8577763. |
the cognitive deficits in both rats and monkeys were prevented by pretreatment with the benzodiazepine receptor antagonist, ro15-1788, which blocked the increase in dopamine turnover and by the dopamine receptor antagonists, haloperidol, clozapine, and sch23390. |
1996-03-14 |
2023-08-12 |
rat |
| F Y Chueh, M T Hsieh, C F Chen, M T Li. DL-tetrahydropalmatine-produced hypotension and bradycardia in rats through the inhibition of central nervous dopaminergic mechanisms. Pharmacology. vol 51. issue 4. 1996-03-12. PMID:8577817. |
the effects of dl-tetrahydropalmatine (thp; a main active substance of the chinese herb corydalis), haloperidol (a dopamine d2 receptor antagonist), apomorphine and amphetamine on cardiovascular function and striatal dopamine (da) release were compared in rats under general anesthesia. |
1996-03-12 |
2023-08-12 |
rat |
| A C Rego, C R Oliveir. Influence of lipid peroxidation on [3H]ketanserin binding to 5-HT2 prefrontal cortex receptors. Neurochemistry international. vol 27. issue 6. 1996-03-08. PMID:8574178. |
in control membranes, the order of inhibition potency of the drugs tested was the following: ketanserin (-log[ic50]=8.56 +/- 0.70] > ritanserin (-log [ic50]=8.13 +/- 0.30)>methysergide (-log[ic50]= 7.42 +/- 0.50)> spiperone (-log[ic50]=7.23 +/- 0.18 > serotonin (-log [ic50] = 6.99 +/- 0.65)> haloperidol (-log[ic50]= 6.95 +/- 0.65) > dopamine (-log [ic50] = 5.82 +/- 0.76). |
1996-03-08 |
2023-08-12 |
Not clear |
| P Seeman, H H Van To. Deriving the therapeutic concentrations for clozapine and haloperidol: the apparent dissociation constant of a neuroleptic at the dopamine D2 or D4 receptor varies with the affinity of the competing radioligand. European journal of pharmacology. vol 291. issue 2. 1996-03-05. PMID:8566176. |
deriving the therapeutic concentrations for clozapine and haloperidol: the apparent dissociation constant of a neuroleptic at the dopamine d2 or d4 receptor varies with the affinity of the competing radioligand. |
1996-03-05 |
2023-08-12 |
human |
| F Iglauer, C Beig, J Dimigen, S Gerold, A Gocht, A Seeburg, S Steier, F Willman. Hereditary compulsive self-mutillating behaviour in laboratory rabbits. Laboratory animals. vol 29. issue 4. 1996-02-28. PMID:8558820. |
in the last 21 cases episodes of automutillation could be regularly interrupted with the dopamine antagonist, haloperidol. |
1996-02-28 |
2023-08-12 |
rabbit |
| E L Dovedov, M Iu Monako. [Effect of the tetrapeptide tuftsin on activity of the monoaminergic system of the brain in experimental pathology]. Voprosy meditsinskoi khimii. vol 41. issue 5. 1996-02-22. PMID:8553620. |
haloperidol therapy caused reciprocal alterations in the activity of monoamine oxidases a and b, in the levels of dopamine, noradrenaline, serotonin, and 5-hydroxyindolyl acetic acid, as well as a decrease in the rate of depolarization-dependent ca(2+)-capture in the synaptosomes of the rat brain cortex and neostriatum (n. caudatus); under these conditions tuftsin normalized the parameters studied to a certain extent, which was more pronounced in n. caudatus. |
1996-02-22 |
2023-08-12 |
rat |
| R Rivest, P Falardeau, T Di Paol. Brain dopamine transporter: gender differences and effect of chronic haloperidol. Brain research. vol 692. issue 1-2. 1996-02-20. PMID:8548314. |
brain dopamine transporter: gender differences and effect of chronic haloperidol. |
1996-02-20 |
2023-08-12 |
rat |
| R Rivest, P Falardeau, T Di Paol. Brain dopamine transporter: gender differences and effect of chronic haloperidol. Brain research. vol 692. issue 1-2. 1996-02-20. PMID:8548314. |
gender differences and the effect of chronic haloperidol on the rat brain dopamine transporter is reported. |
1996-02-20 |
2023-08-12 |
rat |
| R Rivest, P Falardeau, T Di Paol. Brain dopamine transporter: gender differences and effect of chronic haloperidol. Brain research. vol 692. issue 1-2. 1996-02-20. PMID:8548314. |
a reduce clearance rate of dopamine in the striatum after acute and chronic haloperidol was previously reported; the present results indicate that this may occur without changes in the sites of dopamine transport or in gene expression of this transporter. |
1996-02-20 |
2023-08-12 |
rat |
| W Wan, D J Ennulat, B M Cohe. Acute administration of typical and atypical antipsychotic drugs induces distinctive patterns of Fos expression in the rat forebrain. Brain research. vol 688. issue 1-2. 1996-02-14. PMID:8542328. |
administration of single doses of a wide range of typical neuroleptic antipsychotic drugs (including the potent dopamine d2 antagonist haloperidol and the mixed monoamine antagonist chlorpromazine) and atypical antipsychotic drugs (including the weak dopamine d2 antagonists clozapine and thioridazine, the relatively pure d2 antagonist raclopride and the mixed d2 and serotonin s2 antagonist risperidone). |
1996-02-14 |
2023-08-12 |
rat |
| B Ziolkowska, G Horn, A Kupsch, V Höll. The expression of proenkephalin and prodynorphin genes and the induction of c-fos gene by dopaminergic drugs are not altered in the straitum of MPTP-treated mice. Journal of neural transmission. Parkinson's disease and dementia section. vol 9. issue 2-3. 1996-02-01. PMID:8527000. |
the induction of the immediate early gene c-fos by the dopamine d2 receptor antagonist haloperidol was not altered, while the selective d1 receptor agonist skf 38393 failed to induce c-fos in the striatum of mptp-treated mice. |
1996-02-01 |
2023-08-12 |
mouse |
| F Sautel, N Griffon, P Sokoloff, J C Schwartz, C Launay, P Simon, J Costentin, A Schoenfelder, F Garrido, A Man. Nafadotride, a potent preferential dopamine D3 receptor antagonist, activates locomotion in rodents. The Journal of pharmacology and experimental therapeutics. vol 275. issue 3. 1996-02-01. PMID:8531087. |
at low dosage (0.1-1 mg/kg), nafadotride, unlike haloperidol, a dopamine d2 receptor-preferring antagonist, increases spontaneous locomotion of habituated rats and climbing behavior of mice, at doses that do not modify striatal homovanillic acid levels. |
1996-02-01 |
2023-08-12 |
mouse |
| M Didrikse. Effects of antipsychotics on cognitive behaviour in rats using the delayed non-match to position paradigm. European journal of pharmacology. vol 281. issue 3. 1996-01-25. PMID:8521906. |
the acute effects of the dopamine d1 receptor antagonist sch 23390 [(r)-(+)-8-chloro-2,3,4,5-tetrahydro-3-methyl-5-phenyl-1h-3-benzazepi n-7-ol d hemimaleat, the dopamine d2 receptor antagonists raclopride and haloperidol, the compounds with mixed receptor profiles clozapine, risperidone and sertindole, the alpha 1-adrenoceptor antagonist prazosin and scopolamine were investigated in a delay-response task, a test for working memory, for rats. |
1996-01-25 |
2023-08-12 |
rat |
| D M Jackson, N Mohell, A Bengtsson, A Malmber. Why does clozapine stimulate the motor activity of reserpine-pretreated rats when combined with a dopamine D1 receptor agonist? European journal of pharmacology. vol 282. issue 1-3. 1996-01-18. PMID:7498268. |
the stimulation produced by clozapine plus skf38393 was blocked by the selective dopamine d1 receptor antagonist, sch23390 (7-chloro-8-hydroxy-3-methyl-1-phenyl-2,3,4,5- tetrahydro-1h-3-benzapine hydrochloride), while the selective dopamine d2 receptor antagonist, haloperidol, was ineffective. |
1996-01-18 |
2023-08-12 |
rat |