Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
K Shiosaki, K E Asin, D R Britton, W J Giardina, L Bednarz, L Mahan, J Mikusa, A Nikkel, C Wisme. Hyperactivity and behavioral seizures in rodents following treatment with the dopamine D1 receptor agonists A-86929 and ABT-431. European journal of pharmacology. vol 317. issue 2-3. 1997-04-03. PMID:8997599. |
in rats, a-86929 produced a dose-dependent increase in locomotor activity that was attenuated by the selective dopamine d1 receptor antagonist, sch 23390, as well as by higher doses of the dopamine d2 receptor antagonist, haloperidol. |
1997-04-03 |
2023-08-12 |
mouse |
I Creese, D R Burt, S H Snyde. Dopamine receptor binding predicts clinical and pharmacological potencies of antischizophrenic drugs. The Journal of neuropsychiatry and clinical neurosciences. vol 8. issue 2. 1997-04-03. PMID:9081563. |
tritiated haloperidol and tritiated dopamine label postsynaptic dopamine receptors in mammalian brain. |
1997-04-03 |
2023-08-12 |
Not clear |
K J Feasey-Truger, C Alzheimer, G ten Bruggencat. Chronic clozapine versus chronic haloperidol treatment: differential effects on electrically evoked dopamine efflux in the rat caudate putamen, but not in the nucleus accumbens. Naunyn-Schmiedeberg's archives of pharmacology. vol 354. issue 6. 1997-04-02. PMID:8971732. |
chronic clozapine versus chronic haloperidol treatment: differential effects on electrically evoked dopamine efflux in the rat caudate putamen, but not in the nucleus accumbens. |
1997-04-02 |
2023-08-12 |
rat |
K J Feasey-Truger, C Alzheimer, G ten Bruggencat. Chronic clozapine versus chronic haloperidol treatment: differential effects on electrically evoked dopamine efflux in the rat caudate putamen, but not in the nucleus accumbens. Naunyn-Schmiedeberg's archives of pharmacology. vol 354. issue 6. 1997-04-02. PMID:8971732. |
fast cyclic voltammetry at carbon-fibre micro-electrodes was used to investigate the effects of chronic clozapine or haloperidol administration on electrically evoked dopamine efflux in the nucleus accumbens and caudate putamen of the anaesthetized rat. |
1997-04-02 |
2023-08-12 |
rat |
K J Feasey-Truger, C Alzheimer, G ten Bruggencat. Chronic clozapine versus chronic haloperidol treatment: differential effects on electrically evoked dopamine efflux in the rat caudate putamen, but not in the nucleus accumbens. Naunyn-Schmiedeberg's archives of pharmacology. vol 354. issue 6. 1997-04-02. PMID:8971732. |
in contrast, only chronic haloperidol treatment significantly reduced evoked dopamine efflux in the caudate putamen. |
1997-04-02 |
2023-08-12 |
rat |
K J Feasey-Truger, C Alzheimer, G ten Bruggencat. Chronic clozapine versus chronic haloperidol treatment: differential effects on electrically evoked dopamine efflux in the rat caudate putamen, but not in the nucleus accumbens. Naunyn-Schmiedeberg's archives of pharmacology. vol 354. issue 6. 1997-04-02. PMID:8971732. |
these findings demonstrate that chronic treatment with either the atypical neuroleptic, clozapine, or the typical neuroleptic, haloperidol, produce long-term changes in mesolimbic dopamine function; actions which may underlie their antipsychotic efficacy. |
1997-04-02 |
2023-08-12 |
rat |
S Florin, C Suaudeau, J C Meunier, J Costenti. Nociceptin stimulates locomotion and exploratory behaviour in mice. European journal of pharmacology. vol 317. issue 1. 1997-04-02. PMID:8982713. |
increasing doses of the dopamine d2 receptor antagonist haloperidol (0.1-0.5 mg/kg i.p.) |
1997-04-02 |
2023-08-12 |
mouse |
J Ma, S M Brudzynski, L W Leun. Involvement of the nucleus accumbens-ventral pallidal pathway in postictal behavior induced by a hippocampal afterdischarge in rats. Brain research. vol 739. issue 1-2. 1997-04-01. PMID:8955921. |
bilateral injection of haloperidol (5 micrograms/side) or the selective dopamine d2 receptor antagonist, (+/-)-sulpiride (200 ng/side) before the hippocampal ad, into the nac selectively reduced rearings and locomotor activity, but not the number of wet-dog shakes and face washes. |
1997-04-01 |
2023-08-12 |
rat |
K Ishida, Y Ohno, T Ishibashi, M Nakamur. Effects of SM-9018, a novel 5-HT2 and D2 receptor antagonist, on electrically-evoked [3H]acetylcholine release from rat striatal slices. General pharmacology. vol 27. issue 7. 1997-04-01. PMID:8981068. |
sm-9018 was weaker than haloperidol in enhancing the [3h]ach release evoked by higher frequency (3 hz) stimulation, the enhancement being abolished by the depletion of endogenous dopamine with reserpine pretreatment. |
1997-04-01 |
2023-08-12 |
rat |
E Obuchowic. Long-term treatment with chlorpromazine and haloperidol but not with sulpiride and clozapine markedly elevates neuropeptide Y-like immunoreactivity in the rat hypothalamus. Neuropeptides. vol 30. issue 5. 1997-03-28. PMID:8923510. |
the dopamine d2 agonist quinpirole antagonized the effects of chlorpromazine and haloperidol, but it did not change npy-li concentration by itself. |
1997-03-28 |
2023-08-12 |
rat |
J M Vile, P G Strang. D2-like dopamine receptors are not detectable on human peripheral blood lymphocytes. Biological psychiatry. vol 40. issue 9. 1997-03-18. PMID:8896774. |
there is no detectable stereoselectivity for the stereoisomers of butaclamol, and competitions with haloperidol and sulpiride also show no evidence of specific binding to d2-like dopamine receptors. |
1997-03-18 |
2023-08-12 |
human |
T F Meert, P De Haes, N Aerts, G Clinck. Antagonism of the discriminative stimulus properties of cocaine with the combination of a dopamine D1 and D2 antagonist. Acta neurobiologiae experimentalis. vol 56. issue 4. 1997-03-18. PMID:9033125. |
antagonism of the discriminative stimulus properties of 10 mg/kg cocaine was studied in rats by use of the dopamine d1 antagonist sch 23390 and the d2 antagonist haloperidol. |
1997-03-18 |
2023-08-12 |
rat |
T F Meert, P De Haes, N Aerts, G Clinck. Antagonism of the discriminative stimulus properties of cocaine with the combination of a dopamine D1 and D2 antagonist. Acta neurobiologiae experimentalis. vol 56. issue 4. 1997-03-18. PMID:9033125. |
whereas sch 23390 and haloperidol were by themselves unable to antagonize the cueing properties of cocaine, the combination of both dopamine antagonists resulted in a complete blockade of the cocaine cue. |
1997-03-18 |
2023-08-12 |
rat |
J M Delfs, V M Ciaramitaro, J J Soghomonian, M F Chessele. Unilateral nigrostriatal lesions induce a bilateral increase in glutamate decarboxylase messenger RNA in the reticular thalamic nucleus. Neuroscience. vol 71. issue 2. 1997-03-13. PMID:9053794. |
short- (seven day) and long-term (eight month) treatments with the antipsychotic drug haloperidol, in regimens that preferentially block d2 dopamine receptors, induced catalepsy and orofacial dyskinesia, respectively, but did not alter glutamate decarboxylase 67 messenger rna levels in the reticular thalamic nucleus. |
1997-03-13 |
2023-08-12 |
rat |
W Haube. Impairments of movement initiation and execution induced by a blockade of dopamine D1 or D2 receptors are reversed by a blockade of N-methyl-D-aspartate receptors. Neuroscience. vol 73. issue 1. 1997-03-11. PMID:8783236. |
systemic administration of the preferential dopamine d2 antagonist haloperidol (0.1; 0.15 mg/kg, i.p.) |
1997-03-11 |
2023-08-12 |
rat |
B Karolewicz, L Antkiewicz-Michaluk, J Michaluk, J Vetulan. Different effects of chronic administration of haloperidol and pimozide on dopamine metabolism in the rat brain. European journal of pharmacology. vol 313. issue 3. 1997-03-07. PMID:8911913. |
different effects of chronic administration of haloperidol and pimozide on dopamine metabolism in the rat brain. |
1997-03-07 |
2023-08-12 |
rat |
B Karolewicz, L Antkiewicz-Michaluk, J Michaluk, J Vetulan. Different effects of chronic administration of haloperidol and pimozide on dopamine metabolism in the rat brain. European journal of pharmacology. vol 313. issue 3. 1997-03-07. PMID:8911913. |
we investigated the differences between the action of haloperidol and pimozide on dopamine metabolism and on catalepsy in periods up to 6 weeks after cessation of chronic administration of the neuroleptics to male wistar rats. |
1997-03-07 |
2023-08-12 |
rat |
M A Klitenick, M T Taber, H C Fibige. Effects of chronic haloperidol on stress- and stimulation-induced increases in dopamine release: tests of the depolarization block hypothesis. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 15. issue 4. 1997-03-06. PMID:8887997. |
effects of chronic haloperidol on stress- and stimulation-induced increases in dopamine release: tests of the depolarization block hypothesis. |
1997-03-06 |
2023-08-12 |
rat |
M A Klitenick, M T Taber, H C Fibige. Effects of chronic haloperidol on stress- and stimulation-induced increases in dopamine release: tests of the depolarization block hypothesis. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 15. issue 4. 1997-03-06. PMID:8887997. |
as a test of this prediction, rats that had been treated chronically with either saline or haloperidol (0.5 mg/kg x 21 days) were exposed to either acute mild stress or electrical stimulation of the prelimbic region of the prefrontal cortex while extracellular levels of dopamine in the nucleus accumbens were monitored by in vivo microdialysis. |
1997-03-06 |
2023-08-12 |
rat |
M A Klitenick, M T Taber, H C Fibige. Effects of chronic haloperidol on stress- and stimulation-induced increases in dopamine release: tests of the depolarization block hypothesis. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 15. issue 4. 1997-03-06. PMID:8887997. |
a 10-minute exposure to acute stress via tail pinch increased dopamine release by 20% and 18% in the saline and haloperidol groups, respectively. |
1997-03-06 |
2023-08-12 |
rat |