| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Inoue, S Miki, M Seto, T Kikuchi, S Morita, H Ueda, Y Misu, Y Nakat. Aripiprazole, a novel antipsychotic drug, inhibits quinpirole-evoked GTPase activity but does not up-regulate dopamine D2 receptor following repeated treatment in the rat striatum. European journal of pharmacology. vol 321. issue 1. 1997-08-26. PMID:9083792. |
these results indicated that aripiprazole had an antagonistic activity to dopamine d2 receptors with a high affinity, but that the potency of aripiprazole to up-regulate dopamine d2 receptors in the striatum was much smaller than that of haloperidol. |
1997-08-26 |
2023-08-12 |
rat |
| D S Rothblat, J S Schneide. Regionally specific effects of haloperidol and clozapine on dopamine reuptake in the striatum. Neuroscience letters. vol 228. issue 2. 1997-08-25. PMID:9209113. |
regionally specific effects of haloperidol and clozapine on dopamine reuptake in the striatum. |
1997-08-25 |
2023-08-12 |
rat |
| D S Rothblat, J S Schneide. Regionally specific effects of haloperidol and clozapine on dopamine reuptake in the striatum. Neuroscience letters. vol 228. issue 2. 1997-08-25. PMID:9209113. |
this study examined the extent to which local application of the typical neuroleptic haloperidol (hal) or the atypical neuroleptic clozapine (cloz) influences dopamine (da) transporter function in the dorsal and ventral striatum. |
1997-08-25 |
2023-08-12 |
rat |
| H C Akunne, S Z Whetzel, J N Wiley, A E Corbin, F W Ninteman, H Tecle, Y Pei, T A Pugsley, T G Heffne. The pharmacology of the novel and selective sigma ligand, PD 144418. Neuropharmacology. vol 36. issue 1. 1997-08-18. PMID:9144641. |
pd 144418 potentiated the decrease in 5-hydroxytryptophan caused by haloperidol in the mesolimbic region, but by itself had no effect in 5-hydroxytrypamine (5-ht) and dopamine (da) synthesis. |
1997-08-18 |
2023-08-12 |
rat |
| R J Salín-Pascual, R García-Ferreiro, M L Moro-López, C Blanco-Centurión, R Drucker-Colí. Repeated REM sleep deprivation after chronic haloperidol administration in the rat. Psychopharmacology. vol 131. issue 3. 1997-08-14. PMID:9203231. |
repeated haloperidol administration produces up-regulation of dopamine (da) receptors. |
1997-08-14 |
2023-08-12 |
rat |
| K Kurokawa, M Narita, K Koshiya, K Hidaka, J Ohmori, K Sato. Effects of YM-43611, a novel dopamine D2-like receptor antagonist, on immediate early gene expression in the rat forebrain. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 17. issue 1. 1997-08-13. PMID:9194047. |
the pharmacological characteristics of two benzamides, ym-43611, a potent and selective dopamine d3 and d4 antagonist, and ym-09151-2 (nemonapride), were compared with two reference antipsychotic agents, haloperidol and clozapine, in terms of modification of c-fos and related gene expression in the rat forebrain. |
1997-08-13 |
2023-08-12 |
rat |
| M F Roitman, G E Schafe, T E Thiele, I L Bernstei. Dopamine and sodium appetite: antagonists suppress sham drinking of NaCl solutions in the rat. Behavioral neuroscience. vol 111. issue 3. 1997-08-12. PMID:9189275. |
dopamine (d2) receptor antagonists were evaluated (haloperidol [0.1 mg/kg] and raclopride [0.2 mg/kg]), for their effects on sham and real drinking of 0.3 m nacl. |
1997-08-12 |
2023-08-12 |
rat |
| M J Ramírez, E Cenarruzabeitia, B Lasheras, J Del Ri. 5-HT2 receptor regulation of acetylcholine release induced by dopaminergic stimulation in rat striatal slices. Brain research. vol 757. issue 1. 1997-08-12. PMID:9200494. |
[3h]ach release was decreased by the dopamine d2 receptor agonist ly 171555 (quinpirole) and slightly potentiated by the dopamine d2 receptor antagonist haloperidol. |
1997-08-12 |
2023-08-12 |
rat |
| M Yamamoto, Y Mizuki, M Suetsugi, Y Ozawa, M Ooyama, M Suzuk. Effects of dopamine antagonists on changes in spontaneous EEG and locomotor activity in ketamine-treated rats. Pharmacology, biochemistry, and behavior. vol 57. issue 1-2. 1997-07-30. PMID:9164595. |
dopamine antagonists, such as haloperidol (0.3-1 mg/kg ip), and nemonapride (0.3-1 mg/kg ip), reversed the dissociation between the cortical and hippocampal eeg in ketamine (60 mg/kg ip)-treated rats. |
1997-07-30 |
2023-08-12 |
rat |
| S Attarian, M Amalri. Microinfusion of the metabotropic glutamate receptor agonist 1S,3R-1-aminocyclopentane-1,3-dicarboxylic acid into the nucleus accumbens induces dopamine-dependent locomotor activation in the rat. The European journal of neuroscience. vol 9. issue 4. 1997-07-24. PMID:9153588. |
this effect appeared to be mediated by dopamine, since blockade of dopamine receptors with haloperidol (0.05 and 0.1 mg/kg i.p.) |
1997-07-24 |
2023-08-12 |
rat |
| M Volonté, E Monferini, M Cerutti, F Fodritto, F Borsin. BIMG 80, a novel potential antipsychotic drug: evidence for multireceptor actions and preferential release of dopamine in prefrontal cortex. Journal of neurochemistry. vol 69. issue 1. 1997-07-24. PMID:9202309. |
the effect of acute subcutaneous bimg 80, clozapine, haloperidol, risperidone, amperozide, olanzapine, and seroquel was then investigated on dopamine release in medial prefrontal cortex, nucleus accumbens, and striatum in freely moving rats using the microdialysis technique. |
1997-07-24 |
2023-08-12 |
rat |
| M Volonté, E Monferini, M Cerutti, F Fodritto, F Borsin. BIMG 80, a novel potential antipsychotic drug: evidence for multireceptor actions and preferential release of dopamine in prefrontal cortex. Journal of neurochemistry. vol 69. issue 1. 1997-07-24. PMID:9202309. |
(b) haloperidol induced a similar increase in dopamine concentrations in the striatum and nucleus accumbens with no effect in the medial prefrontal cortex. |
1997-07-24 |
2023-08-12 |
rat |
| S Kasper, C Barnas, A Heiden, H P Volz, G Laakmann, H Zeit, H Pfol. Pramipexole as adjunct to haloperidol in schizophrenia. Safety and efficacy. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 7. issue 1. 1997-07-23. PMID:9088887. |
pramipexole, a presynaptic dopamine d2/d3 autoreceptor agonist, has been given to haloperidol-treated patients with schizophrenia (n = 15) in an effort to ameliorate residual positive and negative symptoms that have not been satisfactorily influenced by haloperidol alone. |
1997-07-23 |
2023-08-12 |
Not clear |
| F J Wan, N R Swerdlo. The basolateral amygdala regulates sensorimotor gating of acoustic startle in the rat. Neuroscience. vol 76. issue 3. 1997-07-21. PMID:9135045. |
the prepulse inhibition-disruptive effects of basolateral amygdala lesions were not reversed by systemic injection of the dopamine antagonist haloperidol at doses that totally restored prepulse inhibition in apomorphine-treated rats. |
1997-07-21 |
2023-08-12 |
rat |
| S J Augood, K Westmore, P C Emso. Phenotypic characterization of neurotensin messenger RNA-expressing cells in the neuroleptic-treated rat striatum: a detailed cellular co-expression study. Neuroscience. vol 76. issue 3. 1997-07-21. PMID:9135049. |
that several populations of proneurotensin messenger rna-positive striatal cells may exist, of which one population is sensitive to haloperidol, co-expresses enkephalin messenger rna and is positive for dopamine and adenylate cyclase phosphoprotein-32 messenger rna may be of some significance in neuropsychiatric/neurological disorders given that the translated peptide, neurotensin, is known to influence and interact closely with the dopamine systems. |
1997-07-21 |
2023-08-12 |
rat |
| G Lucas, N Bonhomme, P De Deurwaerdère, M Le Moal, U Spampinat. 8-OH-DPAT, a 5-HT1A agonist and ritanserin, a 5-HT2A/C antagonist, reverse haloperidol-induced catalepsy in rats independently of striatal dopamine release. Psychopharmacology. vol 131. issue 1. 1997-07-21. PMID:9181636. |
in this study, both catalepsy and changes in extracellular levels of striatal dopamine (da) and dihydroxyphenyl acetic acid (dopac) induced by the typical neuroleptic haloperidol (hal) were simultaneously assessed, using intracerebral microdialysis in freely moving rats, in the presence of either the 5-ht1a agonist 8-oh-dpat or the 5-ht2a/c antagonist ritanserin. |
1997-07-21 |
2023-08-12 |
rat |
| C S Biggs, L J Fowler, P S Whitton, M S Star. Extracellular levels of glutamate and aspartate in the entopeduncular nucleus of the rat determined by microdialysis: regulation by striatal dopamine D2 receptors via the indirect striatal output pathway? Brain research. vol 753. issue 1. 1997-07-17. PMID:9125444. |
or bilateral intrastriatal (7 microg/0.5 microl under halothane anaesthesia) administration of the dopamine d2 receptor antagonist haloperidol, but not raclopride (2 mg/kg, i.p.). |
1997-07-17 |
2023-08-12 |
human |
| S Florin, C Suaudeau, J C Meunier, J Costenti. Orphan neuropeptide NocII, a putative pronociceptin maturation product, stimulates locomotion in mice. Neuroreport. vol 8. issue 3. 1997-07-03. PMID:9106751. |
the motor stimulant action of nocii appears to depend largely on dopamine transmission since it is totally reversed by the d1 or the d2 dopamine receptor antagonists sch 23390 and haloperidol. |
1997-07-03 |
2023-08-12 |
mouse |
| T Ishikane, I Kusumi, R Matsubara, S Matsubara, T Koyam. Effects of serotonergic agents on the up-regulation of dopamine D2 receptors induced by haloperidol in rat striatum. European journal of pharmacology. vol 321. issue 2. 1997-07-01. PMID:9063684. |
effects of serotonergic agents on the up-regulation of dopamine d2 receptors induced by haloperidol in rat striatum. |
1997-07-01 |
2023-08-12 |
rat |
| T Ishikane, I Kusumi, R Matsubara, S Matsubara, T Koyam. Effects of serotonergic agents on the up-regulation of dopamine D2 receptors induced by haloperidol in rat striatum. European journal of pharmacology. vol 321. issue 2. 1997-07-01. PMID:9063684. |
chronic treatment with haloperidol (0.1, 0.5 mg/kg, i.p., 3 weeks) increased the number of dopamine d2 receptors, while no increase was observed with the atypical antipsychotic drugs clozapine (10 mg/kg) and trans-5-chloro-2-methyl-2,3,3a, 12b-tetrahydro-1 h-dibenz[2,3:6,7]oxepino[4,5-c]pyrrolidine maleate (org 5222; 0.25 mg/kg). |
1997-07-01 |
2023-08-12 |
rat |