| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L Besret, K J Page, S B Dunnet. The problem of antipsychotic treatment for functional imaging in Huntington's disease: receptor binding, gene expression and locomotor activity after sub-chronic administration and wash-out of haloperidol in the rat. Brain research. vol 853. issue 1. 2000-03-07. PMID:10627316. |
it has been demonstrated that withdrawal from chronic treatment with haloperidol is associated with a long-lasting increase in the number of striatal dopamine d(2) receptors and variable changes in d(1) receptors. |
2000-03-07 |
2023-08-12 |
rat |
| L Besret, K J Page, S B Dunnet. The problem of antipsychotic treatment for functional imaging in Huntington's disease: receptor binding, gene expression and locomotor activity after sub-chronic administration and wash-out of haloperidol in the rat. Brain research. vol 853. issue 1. 2000-03-07. PMID:10627316. |
we have investigated the effect of withdrawal from sub-chronic administration of haloperidol on the density of dopamine receptors, dopamine receptor gene expression, and spontaneous locomotor activity. |
2000-03-07 |
2023-08-12 |
rat |
| b' S M Boye, P P Rompr\\xc3\\xa. Behavioral evidence of depolarization block of dopamine neurons after chronic treatment with haloperidol and clozapine. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 3. 2000-02-18. PMID:10648727.' |
behavioral evidence of depolarization block of dopamine neurons after chronic treatment with haloperidol and clozapine. |
2000-02-18 |
2023-08-12 |
rat |
| b' S M Boye, P P Rompr\\xc3\\xa. Behavioral evidence of depolarization block of dopamine neurons after chronic treatment with haloperidol and clozapine. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 3. 2000-02-18. PMID:10648727.' |
electrophysiological studies have shown that chronic treatment with haloperidol causes depolarization block (db) of dopamine cells in anesthetized and paralyzed rats. |
2000-02-18 |
2023-08-12 |
rat |
| V Kumari, P A Cotter, O F Mulligan, S A Checkley, N S Gray, D R Hemsley, J C Thornton, P J Corr, B K Toone, J A Gra. Effects of d-amphetamine and haloperidol on latent inhibition in healthy male volunteers. Journal of psychopharmacology (Oxford, England). vol 13. issue 4. 2000-02-18. PMID:10667617. |
neuroleptic drugs, such as haloperidol, administered at low doses, potentiate li and effectively reverse disruption of li induced by dopamine agonists in animals. |
2000-02-18 |
2023-08-12 |
human |
| J Maj, Z Rogóz, G Skuz. The anticataleptic effect of 7-OH-DPAT: are dopamine D3 receptors involved? Journal of neural transmission (Vienna, Austria : 1996). vol 106. issue 11-12. 2000-02-15. PMID:10651103. |
the paper examined the effect of 7-oh-dpat (7-hydroxy-n,n-di-n-propyl-2-aminotetralin), a dopamine d3 receptors-prefering agonist, on the catalepsy evoked by reserpine, haloperidol and fluphenazine in rats (male wistar), as well as the influence of nafadotride, a dopamine d3 receptors-prefering antagonist, on that effect. |
2000-02-15 |
2023-08-12 |
rat |
| G Lucas, U Spampinat. Role of striatal serotonin2A and serotonin2C receptor subtypes in the control of in vivo dopamine outflow in the rat striatum. Journal of neurochemistry. vol 74. issue 2. 2000-02-10. PMID:10646521. |
this study investigated, using in vivo microdialysis in the striatum of freely moving rats, the role of striatal serotonin2a (5-ht2a) and 5-ht2c receptor subtypes in the modulation of dopamine (da) and 3, 4-dihydroxyphenylacetic acid (dopac) outflow, both in basal conditions and under activation induced by subcutaneous administration of 0.01 mg/kg haloperidol. |
2000-02-10 |
2023-08-12 |
rat |
| M Markianos, J Hatzimanolis, L Lykoura. Dopamine receptor responsivity in schizophrenic patients before and after switch from haloperidol to risperidone. Psychiatry research. vol 89. issue 2. 2000-02-08. PMID:10646830. |
administration of 5 mg of haloperidol (the hal test) provide information about the responsivity of d2 dopamine receptors in the hypothalamus-hypophysis, and may be a measure of their occupancy during the neuroleptic treatment of schizophrenic patients. |
2000-02-08 |
2023-08-12 |
Not clear |
| b' M Huotari, R Gainetdinov, P T M\\xc3\\xa4nnist\\xc3\\xb. Microdialysis studies on the action of tolcapone on pharmacologically-elevated extracellular dopamine levels in conscious rats. Pharmacology & toxicology. vol 85. issue 5. 2000-02-03. PMID:10608486.' |
however, tolcapone pretreatment (30 mg/kg) multiplied the already high dopamine levels after levodopa, and less so the moderately elevated dopamine levels after gbr-12909 (at 20 mg/kg) alone, but the minor (insignificant) dopamine-elevating effects of haloperidol and (+)-u232 were not altered. |
2000-02-03 |
2023-08-12 |
rat |
| Y Masuda, N Miura, M Suzuki, Y Akagawa, Y Kawarada, M Kawagoe, T Sugiyama, T Shimizu, Y Hishikaw. The fragment of complement 3a lacking the primary 9 amino acids induces promoting activity on mouse voluntary running. The Tohoku journal of experimental medicine. vol 189. issue 1. 2000-02-03. PMID:10622205. |
the effect of the synthesized peptide was demuted by haloperidol but not by a specific dopamine 2 antagonist (-)sulpiride. |
2000-02-03 |
2023-08-12 |
mouse |
| Y Masuda, N Miura, M Suzuki, Y Akagawa, Y Kawarada, M Kawagoe, T Sugiyama, T Shimizu, Y Hishikaw. The fragment of complement 3a lacking the primary 9 amino acids induces promoting activity on mouse voluntary running. The Tohoku journal of experimental medicine. vol 189. issue 1. 2000-02-03. PMID:10622205. |
the present findings clearly indicate that il-2 produces the c3a fragment lacking the primary 9 amino acids which directly promotes the voluntary running, and that the effect of the fragment is mediated by an activity of haloperidol on the neurons, except for the dopamine 2 antagonism. |
2000-02-03 |
2023-08-12 |
mouse |
| H Becq, O Bosler, M Geffard, A Enjalbert, J P Herma. Anatomical and functional reconstruction of the nigrostriatal system in vitro: selective innervation of the striatum by dopaminergic neurons. Journal of neuroscience research. vol 58. issue 4. 1999-12-22. PMID:10533047. |
thus, blockade, under basal conditions, of the effect of spontaneously released dopamine by the d2 receptor antagonist haloperidol leads to the activation of c-fos expression in the striatum. |
1999-12-22 |
2023-08-12 |
rat |
| S Yamada, M Harano, N Annoh, M Tanak. Dopamine D(3) receptors modulate evoked dopamine release from slices of rat nucleus accumbens via muscarinic receptors, but not from the striatum. The Journal of pharmacology and experimental therapeutics. vol 291. issue 3. 1999-12-20. PMID:10565816. |
haloperidol, a preferential dopamine d(2) receptor antagonist, enhanced the evoked dopamine release from both the striatum and nucleus accumbens. |
1999-12-20 |
2023-08-12 |
rat |
| M Geurts, E Hermans, J M Maloteau. Enhanced striatal dopamine D(2) receptor-induced [35S]GTPgammaS binding after haloperidol treatment. European journal of pharmacology. vol 382. issue 2. 1999-12-17. PMID:10528146. |
enhanced striatal dopamine d(2) receptor-induced [35s]gtpgammas binding after haloperidol treatment. |
1999-12-17 |
2023-08-12 |
rat |
| M Geurts, E Hermans, J M Maloteau. Enhanced striatal dopamine D(2) receptor-induced [35S]GTPgammaS binding after haloperidol treatment. European journal of pharmacology. vol 382. issue 2. 1999-12-17. PMID:10528146. |
dopamine receptor-g protein coupling and dopamine d(2) receptor density were assessed in rats treated for 3 weeks with either haloperidol (2 mg/kg; i.p.) |
1999-12-17 |
2023-08-12 |
rat |
| M Geurts, E Hermans, J M Maloteau. Enhanced striatal dopamine D(2) receptor-induced [35S]GTPgammaS binding after haloperidol treatment. European journal of pharmacology. vol 382. issue 2. 1999-12-17. PMID:10528146. |
when measured in the presence of a saturating concentration of a dopamine d(2) receptor antagonist, the response to dopamine was not significantly affected by haloperidol treatment. |
1999-12-17 |
2023-08-12 |
rat |
| M Geurts, E Hermans, J M Maloteau. Enhanced striatal dopamine D(2) receptor-induced [35S]GTPgammaS binding after haloperidol treatment. European journal of pharmacology. vol 382. issue 2. 1999-12-17. PMID:10528146. |
taken together, these results indicate that a functional pool of dopamine d(2) receptors is increased after prolonged haloperidol administration. |
1999-12-17 |
2023-08-12 |
rat |
| I E De Souza, G J McBean, G E Meredit. Chronic haloperidol treatment impairs glutamate transport in the rat striatum. European journal of pharmacology. vol 382. issue 2. 1999-12-17. PMID:10528149. |
chronic blockade of dopamine d(2) receptors with haloperidol elevates extracellular glutamate levels in the striatum. |
1999-12-17 |
2023-08-12 |
rat |
| J Yu, L Källström, F A Wiesel, A E Johnso. Neurochemical changes in the entopeduncular nucleus and increased oral behavior in rats treated subchronically with clozapine or haloperidol. Synapse (New York, N.Y.). vol 34. issue 3. 1999-12-10. PMID:10523757. |
in addition, vacuous chewing movements (vcm) were measured throughout the drug administration period as a functional indicator of drug action and changes in striatal dopamine d(2)-receptor binding were measured as a positive control for d(2)-receptor antagonist properties of haloperidol and clozapine. |
1999-12-10 |
2023-08-12 |
rat |
| J M Gulley, M Kuwajima, E Mayhill, G V Rebe. Behavior-related changes in the activity of substantia nigra pars reticulata neurons in freely moving rats. Brain research. vol 845. issue 1. 1999-12-10. PMID:10529445. |
subsequent injection with the dopamine antagonist haloperidol (1.0 mg/kg, s.c.) reversed amphetamine-induced inhibitions in all tested cells, which supports a role for dopamine in this effect. |
1999-12-10 |
2023-08-12 |
rat |