Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
A Baghdadli, V Gonnier, C Aussillou. [Review of psychopharmacological treatments in adolescents and adults with autistic disorders]. L'Encephale. vol 28. issue 3 Pt 1. 2002-10-29. PMID:12091786. |
haloperidol (dopamine antagonist): the effects of this molecule have been broadly studied in autism. |
2002-10-29 |
2023-08-12 |
Not clear |
Zitao Zhu, Muriel Bartol, Kezhong Shen, Steven W Johnso. Excitatory effects of dopamine on subthalamic nucleus neurons: in vitro study of rats pretreated with 6-hydroxydopamine and levodopa. Brain research. vol 945. issue 1. 2002-10-07. PMID:12113949. |
this excitatory effect of dopamine was mimicked by a d2 receptor agonist (quinpirole), and was reduced by the d2 antagonists haloperidol, clozapine and sulpiride. |
2002-10-07 |
2023-08-12 |
rat |
Ko-Woon Lee, Jang-Hee Hong, In Young Choi, Yongzhe Che, Ja-Kyeong Lee, Sung-Don Yang, Chang-Woo Song, Ho Sung Kang, Jae-Heun Lee, Jai Sung Noh, Hee-Sup Shin, Pyung-Lim Ha. Impaired D2 dopamine receptor function in mice lacking type 5 adenylyl cyclase. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 18. 2002-10-03. PMID:12223546. |
interestingly, both haloperidol and clozapine at low doses remarkably increased the locomotion of ac5(-/-) in the open field test that was produced in part by a common mechanism that involved the increased activation of d1 dopamine receptors. |
2002-10-03 |
2023-08-12 |
mouse |
Vito Sanci, Sylvain Houle, Jean N DaSilv. No change in dopamine D1 receptor in vivo binding in rats after sub-chronic haloperidol treatment. Canadian journal of physiology and pharmacology. vol 80. issue 1. 2002-10-01. PMID:11911224. |
no change in dopamine d1 receptor in vivo binding in rats after sub-chronic haloperidol treatment. |
2002-10-01 |
2023-08-12 |
rat |
Vito Sanci, Sylvain Houle, Jean N DaSilv. No change in dopamine D1 receptor in vivo binding in rats after sub-chronic haloperidol treatment. Canadian journal of physiology and pharmacology. vol 80. issue 1. 2002-10-01. PMID:11911224. |
a frequent side effect in the long-term treatment of schizophrenia with the dopamine d2 antagonist haloperidol (hal) is the appearance of tardive dyskinesia or, in animals, of repetitive involuntary vacuous chewing movements (vcms). |
2002-10-01 |
2023-08-12 |
rat |
Barbara R Sommer, Lowell C Wise, Helena C Kraeme. Is dopamine administration possibly a risk factor for delirium? Critical care medicine. vol 30. issue 7. 2002-09-17. PMID:12130971. |
we explored the possibility that the administration of intravenous dopamine increases the risk for delirium as manifested by need for haloperidol. |
2002-09-17 |
2023-08-12 |
Not clear |
Huei-Ching Hsieh, Hui-Yun Li, Ming-Yu Lin, Ya-Fen Chiou, Shao-Yun Lin, Chung-Hung Wong, Jin-Chung Che. Spatial and temporal profile of haloperidol-induced immediate-early gene expression and phosphoCREB binding in the dorsal and ventral striatum of amphetamine-sensitized rats. Synapse (New York, N.Y.). vol 45. issue 4. 2002-09-13. PMID:12125044. |
to determine if d(2) dopamine receptor-mediated nuclear signaling is altered during the development of amphetamine sensitization, we examined the expression of immediate-early gene (ieg) products, fos, jun, and fos-related antigen (fra), in both controls and amphetamine-sensitized rats after a challenge with the d(2) antagonist haloperidol. |
2002-09-13 |
2023-08-12 |
rat |
Vincenzo Di Matteo, Marisa Cacchio, Camillo Di Giulio, Giuseppe Di Giovanni, Ennio Esposit. Biochemical evidence that the atypical antipsychotic drugs clozapine and risperidone block 5-HT(2C) receptors in vivo. Pharmacology, biochemistry, and behavior. vol 71. issue 4. 2002-09-11. PMID:11888552. |
therefore, the effects of clozapine (5 mg/kg ip), risperidone (0.08 mg/kg ip) and of the typical antipsychotic haloperidol (0.1 mg/kg ip) were studied on the extracellular concentration of dopamine (da) in the nucleus accumbens of chloral hydrate-anesthetized rats, using intracerebral microdialysis. |
2002-09-11 |
2023-08-12 |
human |
Carlo Cavallotti, Federica Nuti, Paolo Bruzzone, Massimo Mancon. Age-related changes in dopamine D2 receptors in rat heart and coronary vessels. Clinical and experimental pharmacology & physiology. vol 29. issue 5-6. 2002-08-29. PMID:12010185. |
the greater sensitivity to displacement by amisulpride, bromocriptine, domperidone, haloperidol, raclopride and l-sulpiride than to displacement by n-propyl-norapomorphine, quinpirole and clozapine suggests that the binding sites observed in these experiments are likely to belong to the dopamine d2 receptor subtype. |
2002-08-29 |
2023-08-12 |
rat |
N Hussain, B A Flumerfelt, N Rajakuma. Muscarinic, adenosine A(2) and histamine H(3) receptor modulation of haloperidol-induced c-fos expression in the striatum and nucleus accumbens. Neuroscience. vol 112. issue 2. 2002-08-29. PMID:12044460. |
it is generally believed that haloperidol exerts its motor side effects and therapeutic effects mainly by antagonizing dopamine d(2) receptors in the striatum and the nucleus accumbens, respectively. |
2002-08-29 |
2023-08-12 |
Not clear |
Ryan K Bachtell, Natalia O Tsivkovskaia, Andrey E Ryabini. Alcohol-induced c-Fos expression in the Edinger-Westphal nucleus: pharmacological and signal transduction mechanisms. The Journal of pharmacology and experimental therapeutics. vol 302. issue 2. 2002-08-29. PMID:12130710. |
in addition, 10 mg/kg 2-(2,3-dihydro-2-methoxy-1,4-benzodioxin-2-yl)4,5-dihydro-1h-imidazole (rx 821002), an alpha(2a/d)-adrenoceptor antagonist, and 20 mg/kg haloperidol, a dopamine antagonist, also block alcohol-induced c-fos expression in edinger-westphal neurons. |
2002-08-29 |
2023-08-12 |
Not clear |
Yosuke Uchitom. [Management of psychiatric symptoms in cancer patients]. Gan to kagaku ryoho. Cancer & chemotherapy. vol 29. issue 7. 2002-08-09. PMID:12146016. |
haloperidol, a neuroleptic agent (antipsychotic) that is a potent dopamine blocker, is the drug of choice for the treatment of delirium in persons with cancer because of the low incidence of related cardiovascular and anticholinergic effects. |
2002-08-09 |
2023-08-12 |
Not clear |
Gurpreet Kaur, Shrinivas K Kulkarn. Studies on modulation of feeding behavior by atypical antipsychotics in female mice. Progress in neuro-psychopharmacology & biological psychiatry. vol 26. issue 2. 2002-07-22. PMID:11817504. |
the aim of this study was to examine the effects of different doses of typical antipsychotics, chlorpromazine (0.25-1 mg/kg) and haloperidol (0.25-1 mg/kg), and atypical antipsychotics, clozapine (0.5-2 mg/kg), olanzapine (0.25-1 mg/kg), risperidone (0.5-2 mg/kg), sulpiride (10-40 mg/kg) and dopamine d1 antagonist, sch 23390 (0.25-1 mg/kg) on feeding behavior at different time intervals after acute administration. |
2002-07-22 |
2023-08-12 |
mouse |
Eero Pekkone, Jyrki Hirvonen, Jyrki Ahveninen, Seppo Kähkönen, Seppo Kaakkola, Juha Huttunen, Iiro P Jääskeläine. Memory-based comparison process not attenuated by haloperidol: a combined MEG and EEG study. Neuroreport. vol 13. issue 1. 2002-07-18. PMID:11924884. |
we used simultaneously magnetoencephalography and electroencephalography to investigate, whether a single dose of haloperidol, a dopamine d2-receptor antagonist, modulates preattentive auditory processing using a randomized, double-blind, placebo-controlled crossover design. |
2002-07-18 |
2023-08-12 |
Not clear |
Moshe Rehavi, Netta Roz, Abraham Weizma. Chronic clozapine, but not haloperidol, treatment affects rat brain vesicular monoamine transporter 2. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 12. issue 3. 2002-07-16. PMID:12007678. |
we compared the effect of chronic clozapine and haloperidol treatment on the expression of rat brain vesicular monoamine transporter (vmat(2)) as well as on the membranal presynaptic transporters for serotonin, dopamine and noradrenaline. |
2002-07-16 |
2023-08-12 |
rat |
I Gil-ad, B Shtaif, R Shiloh, A Weizma. Evaluation of the neurotoxic activity of typical and atypical neuroleptics: relevance to iatrogenic extrapyramidal symptoms. Cellular and molecular neurobiology. vol 21. issue 6. 2002-06-25. PMID:12043843. |
perphenazine, haloperidol, clozapine, sulpiride, and risperidone (10-100 microm) were administered, either alone or combined with dopamine, to primary mouse neuronal or intact brain culture and to a human neuroblastoma (nb) cell line (sk-n-sh). |
2002-06-25 |
2023-08-12 |
mouse |
Fernando Catalina, Leon Milewich, William Frawley, Vinay Kumar, Michael Bennet. Decrease of core body temperature in mice by dehydroepiandrosterone. Experimental biology and medicine (Maywood, N.J.). vol 227. issue 6. 2002-06-21. PMID:12037127. |
because serotonin and dopamine can regulate (decrease) body temperature, we treated mice with haloperidol (dopamine receptor antagonist), 5,7-dihydroxytryptamine (serotonin production inhibitor), or ritanserin (serotonin receptor antagonist) prior to injection of dhea. |
2002-06-21 |
2023-08-12 |
mouse |
J E Belforte, C Magariños-Azcone, I Armando, W Buño, J H Paz. Pharmacological involvement of the calcium channel blocker flunarizine in dopamine transmission at the striatum. Parkinsonism & related disorders. vol 8. issue 1. 2002-06-20. PMID:11472878. |
intrastriatal injections of haloperidol (5microg/microl), an antagonist of dopamine d(2) receptors, or the sodium channel blocker lidocaine (40microg/microl), were given in order to compare their effects to those observed with flunarizine. |
2002-06-20 |
2023-08-12 |
rat |
Stacy L Sell, Charles P Franc. Cocaine and amphetamine attenuate the discriminative stimulus effects of naltrexone in opioid-dependent rhesus monkeys. The Journal of pharmacology and experimental therapeutics. vol 301. issue 3. 2002-06-19. PMID:12023543. |
in contrast, the dopamine antagonist haloperidol shifted the naltrexone dose-effect curve 5-fold leftward. |
2002-06-19 |
2023-08-12 |
monkey |
J Amiel Rosenkranz, Anthony A Grac. Dopamine-mediated modulation of odour-evoked amygdala potentials during pavlovian conditioning. Nature. vol 417. issue 6886. 2002-06-10. PMID:12015602. |
the dopamine antagonist haloperidol blocked the psp enhancement and associated increased neuronal excitability, without reversing previous conditioning. |
2002-06-10 |
2023-08-12 |
rat |