| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| K P Singh, Mandavi Sing. Effect of prenatal haloperidol exposure on behavioral alterations in rats. Neurotoxicology and teratology. vol 24. issue 4. 2003-02-26. PMID:12127895. |
pregnant charles-foster rats were exposed to haloperidol (hal), a neuroleptic drug that binds to and blocks dopamine (da) receptor subtypes at a dose of 2.5 mg/kg body weight (intraperitoneally) from gestation day (gd) 12 to 20. |
2003-02-26 |
2023-08-12 |
rat |
| Koichi Fusa, Tadashi Saigusa, Noriaki Koshikawa, Alexander R Cool. Tyrosine-induced release of dopamine is under inhibitory control of presynaptic dopamine D2 and, probably, D3 receptors in the dorsal striatum, but not in the nucleus accumbens. European journal of pharmacology. vol 448. issue 2-3. 2003-02-12. PMID:12144934. |
haloperidol, a dopamine d2-like receptor antagonist, given systemically at a dose, which alone did not significantly affect basal dopamine levels (10 nmol/kg i.p. |
2003-02-12 |
2023-08-12 |
rat |
| Koichi Fusa, Tadashi Saigusa, Noriaki Koshikawa, Alexander R Cool. Tyrosine-induced release of dopamine is under inhibitory control of presynaptic dopamine D2 and, probably, D3 receptors in the dorsal striatum, but not in the nucleus accumbens. European journal of pharmacology. vol 448. issue 2-3. 2003-02-12. PMID:12144934. |
this haloperidol treatment antagonized only the quinpirole-induced, but not the pd 128907-induced reduction in dopamine levels seen in tyrosine-treated rats. |
2003-02-12 |
2023-08-12 |
rat |
| Andrew Chih Wei Huang, Sigmund Hsia. Haloperidol attenuates rewarding and aversively conditioned suppression of saccharin solution intake: reevaluation of the anhedonia hypothesis of dopamine blocking. Behavioral neuroscience. vol 116. issue 4. 2003-01-07. PMID:12148931. |
haloperidol attenuates rewarding and aversively conditioned suppression of saccharin solution intake: reevaluation of the anhedonia hypothesis of dopamine blocking. |
2003-01-07 |
2023-08-12 |
Not clear |
| Andrew Chih Wei Huang, Sigmund Hsia. Haloperidol attenuates rewarding and aversively conditioned suppression of saccharin solution intake: reevaluation of the anhedonia hypothesis of dopamine blocking. Behavioral neuroscience. vol 116. issue 4. 2003-01-07. PMID:12148931. |
the dopamine (da) antagonist, haloperidol, affected the conditioned suppression of a saccharin solution intake (the conditioned stimulus, cs) induced by amphetamine (amph) and lithium chloride (licl) unconditioned stimuli (uss). |
2003-01-07 |
2023-08-12 |
Not clear |
| b' Ibrahim G\\xc3\\xbcner, Nermin Yelmen, G\\xc3\\xbclderen Sahin, T\\xc3\\xbclin Oru\\xc3\\xa. The effect of intracerebroventricular dopamine administration on the respiratory response to hypoxia. The Tohoku journal of experimental medicine. vol 196. issue 4. 2003-01-06. PMID:12086150.' |
administration of dopamine antagonists haloperidol (0.1 mg) and domperidone (0.07 mg) in chemodenervated rabbits, the significant increases in v(t), v(e) and bp were observed. |
2003-01-06 |
2023-08-12 |
Not clear |
| Norio Yasui-Furukori, Tsuyoshi Kondo, Akihito Suzuki, Kazuo Mihara, Sunao Kanek. Comparison of prolactin concentrations between haloperidol and risperidone treatments in the same female patients with schizophrenia. Psychopharmacology. vol 162. issue 1. 2003-01-02. PMID:12107619. |
however, from a purely pharmacological point of view, prolactin response per drug concentration was more sensitive during haloperidol treatment than risperidone treatment, probably resulting from the potent and selective antagonistic effect of haloperidol on dopamine d(2) receptor, compared with the broader pharmacological spectrum of risperidone. |
2003-01-02 |
2023-08-12 |
human |
| Lucy Chu, Ruth I Woo. Castration, dopamine and food choice: a cost/benefit test in male hamsters. Behavioural brain research. vol 136. issue 1. 2002-11-29. PMID:12385798. |
the effect of the dopamine antagonist, haloperidol, on instrumental responses in intact and castrated males was also determined. |
2002-11-29 |
2023-08-12 |
rat |
| Lucy Chu, Ruth I Woo. Castration, dopamine and food choice: a cost/benefit test in male hamsters. Behavioural brain research. vol 136. issue 1. 2002-11-29. PMID:12385798. |
dopamine is central to this response because haloperidol (1.0 mg/kg i.p.) |
2002-11-29 |
2023-08-12 |
rat |
| M M Marcus, A Malmerfelt, S Nyberg, T H Svensso. Biochemical effects in brain of low doses of haloperidol are qualitatively similar to those of high doses. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 12. issue 5. 2002-11-22. PMID:12208555. |
here, in vivo voltammetry in anaesthetised, pargyline-pretreated rats was used to measure dopamine output in the two subdivisions of the nac and, in addition, immunohistochemistry was used to assess fli activation in dopamine target areas, following acute haloperidol administration. |
2002-11-22 |
2023-08-12 |
rat |
| M M Marcus, A Malmerfelt, S Nyberg, T H Svensso. Biochemical effects in brain of low doses of haloperidol are qualitatively similar to those of high doses. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 12. issue 5. 2002-11-22. PMID:12208555. |
haloperidol, 0.001 and 0.01 mg/kg i.v., caused a significantly higher dopamine output in the core than in the shell of the nac. |
2002-11-22 |
2023-08-12 |
rat |
| Stefania Bonaccorso, Herbert Y Meltzer, Zhu Li, Jin Dai, Anna R Alboszta, Junji Ichikaw. SR46349-B, a 5-HT(2A/2C) receptor antagonist, potentiates haloperidol-induced dopamine release in rat medial prefrontal cortex and nucleus accumbens. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 27. issue 3. 2002-11-15. PMID:12225700. |
the combination of m100907, a putative antipsychotic drug (apd) and serotonin (5-ht)(2a) antagonist, and the typical apd haloperidol, can enhance dopamine (da) release in rat medial prefrontal cortex (mpfc), an effect which has been postulated to be of value to improve cognition and negative symptoms. |
2002-11-15 |
2023-08-12 |
rat |
| Paolo Bruzzone, Vito D'Andrea, Cecilia Motta, Carlo Cavallott. Occurrence of dopaminergic (D(2)) receptors within the rabbit pulmonary circulation. Pulmonary pharmacology & therapeutics. vol 15. issue 4. 2002-11-12. PMID:12220945. |
the greater sensitivity to displacement by domperidone, haloperidol, and bromocriptine than to displacement by n-propyl-nor-apomorphine, quinpirole and clozapine suggests that the binding sites observed in extraparenchymal, large and medium-sized branches of the rabbit pulmonary and bronchial arteries belong, likely, to the dopamine d(2) receptor subtype. |
2002-11-12 |
2023-08-12 |
rabbit |
| Nicholas H Caskey, Murray E Jarvik, William C Wirshing, Damian C Madsen, Paula N Iwamoto-Schaap, Naomi I Eisenberger, Lorena Huerta, Scott M Terrace, Richard E Olmstea. Modulating tobacco smoking rates by dopaminergic stimulation and blockade. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco. vol 4. issue 3. 2002-11-07. PMID:12215234. |
in prior human studies, a dopaminergic antagonist, haloperidol, increased smoking and/or nicotine intake, and a dopamine agonist, bromocriptine, decreased smoking. |
2002-11-07 |
2023-08-12 |
human |
| Stephen R Wachtel, Amanda Ortengren, Harriet de Wi. The effects of acute haloperidol or risperidone on subjective responses to methamphetamine in healthy volunteers. Drug and alcohol dependence. vol 68. issue 1. 2002-11-05. PMID:12167550. |
the goal of this study was to examine the effects of haloperidol, a drug that primarily blocks dopamine receptors, and risperidone, a drug that blocks both dopamine and serotonin receptors, on the physiological and subjective effects of methamphetamine in healthy volunteers. |
2002-11-05 |
2023-08-12 |
human |
| A Baghdadli, V Gonnier, C Aussillou. [Review of psychopharmacological treatments in adolescents and adults with autistic disorders]. L'Encephale. vol 28. issue 3 Pt 1. 2002-10-29. PMID:12091786. |
haloperidol (dopamine antagonist): the effects of this molecule have been broadly studied in autism. |
2002-10-29 |
2023-08-12 |
Not clear |
| Zitao Zhu, Muriel Bartol, Kezhong Shen, Steven W Johnso. Excitatory effects of dopamine on subthalamic nucleus neurons: in vitro study of rats pretreated with 6-hydroxydopamine and levodopa. Brain research. vol 945. issue 1. 2002-10-07. PMID:12113949. |
this excitatory effect of dopamine was mimicked by a d2 receptor agonist (quinpirole), and was reduced by the d2 antagonists haloperidol, clozapine and sulpiride. |
2002-10-07 |
2023-08-12 |
rat |
| Ko-Woon Lee, Jang-Hee Hong, In Young Choi, Yongzhe Che, Ja-Kyeong Lee, Sung-Don Yang, Chang-Woo Song, Ho Sung Kang, Jae-Heun Lee, Jai Sung Noh, Hee-Sup Shin, Pyung-Lim Ha. Impaired D2 dopamine receptor function in mice lacking type 5 adenylyl cyclase. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 18. 2002-10-03. PMID:12223546. |
interestingly, both haloperidol and clozapine at low doses remarkably increased the locomotion of ac5(-/-) in the open field test that was produced in part by a common mechanism that involved the increased activation of d1 dopamine receptors. |
2002-10-03 |
2023-08-12 |
mouse |
| Vito Sanci, Sylvain Houle, Jean N DaSilv. No change in dopamine D1 receptor in vivo binding in rats after sub-chronic haloperidol treatment. Canadian journal of physiology and pharmacology. vol 80. issue 1. 2002-10-01. PMID:11911224. |
no change in dopamine d1 receptor in vivo binding in rats after sub-chronic haloperidol treatment. |
2002-10-01 |
2023-08-12 |
rat |
| Vito Sanci, Sylvain Houle, Jean N DaSilv. No change in dopamine D1 receptor in vivo binding in rats after sub-chronic haloperidol treatment. Canadian journal of physiology and pharmacology. vol 80. issue 1. 2002-10-01. PMID:11911224. |
a frequent side effect in the long-term treatment of schizophrenia with the dopamine d2 antagonist haloperidol (hal) is the appearance of tardive dyskinesia or, in animals, of repetitive involuntary vacuous chewing movements (vcms). |
2002-10-01 |
2023-08-12 |
rat |