| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Manocha, K K Sharma, P K Mediratt. Possible mechanism of anticonvulsant effect of ketamine in mice. Indian journal of experimental biology. vol 39. issue 10. 2002-04-01. PMID:11883507. |
the anticonvulsant effect of ketamine was antagonized neither by naloxone (low as well as high doses) nor sulpiride, but was attenuated by haloperidol, a dopamine (d2)/sigma receptor antagonist. |
2002-04-01 |
2023-08-12 |
mouse |
| N M de Bruin, E L van Luijtelaar, A R Cools, B A Ellenbroe. Dopamine characteristics in rat genotypes with distinct susceptibility to epileptic activity: apomorphine-induced stereotyped gnawing and novelty/amphetamine-induced locomotor stimulation. Behavioural pharmacology. vol 12. issue 6-7. 2002-03-20. PMID:11742146. |
in a previous study, it was found that spike-wave discharge incidence decreased in the following order in four rat genotypes during baseline and following injection with the dopamine antagonist haloperidol: apomorphine-susceptible (apo-sus) > wag/rij > apomorphine-unsusceptible (apo-unsus) and aci rats. |
2002-03-20 |
2023-08-12 |
rat |
| William S Cobb, Elizabeth D Abercrombi. Distinct roles for nigral GABA and glutamate receptors in the regulation of dendritic dopamine release under normal conditions and in response to systemic haloperidol. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 4. 2002-02-26. PMID:11850467. |
distinct roles for nigral gaba and glutamate receptors in the regulation of dendritic dopamine release under normal conditions and in response to systemic haloperidol. |
2002-02-26 |
2023-08-12 |
Not clear |
| William S Cobb, Elizabeth D Abercrombi. Distinct roles for nigral GABA and glutamate receptors in the regulation of dendritic dopamine release under normal conditions and in response to systemic haloperidol. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 4. 2002-02-26. PMID:11850467. |
the present studies used in vivo microdialysis to determine the potential roles of nigral gaba and glutamate receptors in the regulation of dendritic dopamine release under normal conditions and when dopamine signaling in the basal ganglia is compromised after systemic haloperidol administration. |
2002-02-26 |
2023-08-12 |
Not clear |
| William S Cobb, Elizabeth D Abercrombi. Distinct roles for nigral GABA and glutamate receptors in the regulation of dendritic dopamine release under normal conditions and in response to systemic haloperidol. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 4. 2002-02-26. PMID:11850467. |
systemic haloperidol administration significantly increased the extracellular dopamine measured in the sn. |
2002-02-26 |
2023-08-12 |
Not clear |
| William S Cobb, Elizabeth D Abercrombi. Distinct roles for nigral GABA and glutamate receptors in the regulation of dendritic dopamine release under normal conditions and in response to systemic haloperidol. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 4. 2002-02-26. PMID:11850467. |
blockade of nigral gaba(a) receptors by local bicuculline application did not alter this effect of systemic haloperidol, despite the bicuculline-induced increase in spontaneous dendritic dopamine efflux. |
2002-02-26 |
2023-08-12 |
Not clear |
| William S Cobb, Elizabeth D Abercrombi. Distinct roles for nigral GABA and glutamate receptors in the regulation of dendritic dopamine release under normal conditions and in response to systemic haloperidol. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 4. 2002-02-26. PMID:11850467. |
in contrast, nigral application of either glutamate receptor antagonist significantly attenuated the increases in dendritic dopamine efflux elicited by systemic haloperidol. |
2002-02-26 |
2023-08-12 |
Not clear |
| William S Cobb, Elizabeth D Abercrombi. Distinct roles for nigral GABA and glutamate receptors in the regulation of dendritic dopamine release under normal conditions and in response to systemic haloperidol. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 4. 2002-02-26. PMID:11850467. |
circuit-level changes in the basal ganglia involving an increased glutamatergic drive to the sn appear to underlie the increase in dendritic dopamine release that occurs in response to systemic haloperidol administration. |
2002-02-26 |
2023-08-12 |
Not clear |
| S Morisset, C Pilon, J Tardivel-Lacombe, D Weinstein, W Rostene, C Betancur, P Sokoloff, J C Schwartz, J M Arran. Acute and chronic effects of methamphetamine on tele-methylhistamine levels in mouse brain: selective involvement of the D(2) and not D(3) receptor. The Journal of pharmacology and experimental therapeutics. vol 300. issue 2. 2002-02-25. PMID:11805225. |
repeated methamphetamine administration also resulted in a modified balance in the opposite influences of dopamine and serotonin on histaminergic neurons as revealed by the enhanced response to haloperidol and abolished response to ketanserin, respectively. |
2002-02-25 |
2023-08-12 |
mouse |
| G A MacGibbon, L C Hamilton, S F Crocker, W J Costain, K M Murphy, H A Robertson, E M Denovan-Wrigh. Immediate-early gene response to methamphetamine, haloperidol, and quinolinic acid is not impaired in Huntington's disease transgenic mice. Journal of neuroscience research. vol 67. issue 3. 2002-02-25. PMID:11813242. |
to investigate the possibility that the immediate-early gene (ieg) response is defective in symptomatic hd mice leading to a lack of response to these compounds, we examined the expression of c-fos and krox 24 after administration of the indirect dopamine agonist methamphetamine, the dopamine d(2) receptor antagonist haloperidol and the neurotoxin qa in 5- and 10-week-old r6/2 transgenic hd and wild-type mice. |
2002-02-25 |
2023-08-12 |
mouse |
| B H Westerink, Y Kawahara, P De Boer, C Geels, J B De Vries, H V Wikström, A Van Kalkeren, B Van Vliet, C G Kruse, S K Lon. Antipsychotic drugs classified by their effects on the release of dopamine and noradrenaline in the prefrontal cortex and striatum. European journal of pharmacology. vol 412. issue 2. 2002-02-21. PMID:11165224. |
dose-effect curves were established for the effects of the antipsychotic drugs haloperidol, clozapine, olanzapine, risperidone and ziprasidone on extracellular levels of dopamine and noradrenaline in the medial prefrontal cortex, and of dopamine in the striatum. |
2002-02-21 |
2023-08-12 |
Not clear |
| B H Westerink, Y Kawahara, P De Boer, C Geels, J B De Vries, H V Wikström, A Van Kalkeren, B Van Vliet, C G Kruse, S K Lon. Antipsychotic drugs classified by their effects on the release of dopamine and noradrenaline in the prefrontal cortex and striatum. European journal of pharmacology. vol 412. issue 2. 2002-02-21. PMID:11165224. |
haloperidol was more effective in stimulating the release of dopamine in the striatum, whereas clozapine was much more effective in the medial prefrontal cortex. |
2002-02-21 |
2023-08-12 |
Not clear |
| B H Westerink, Y Kawahara, P De Boer, C Geels, J B De Vries, H V Wikström, A Van Kalkeren, B Van Vliet, C G Kruse, S K Lon. Antipsychotic drugs classified by their effects on the release of dopamine and noradrenaline in the prefrontal cortex and striatum. European journal of pharmacology. vol 412. issue 2. 2002-02-21. PMID:11165224. |
co-administration of the 5-ht(2) receptor agonist (+/-)-2,5-dimethoxy-4-iodoamphetamine hcl (doi) (850 nmol/kg) with clozapine (10 micromol/kg) or haloperidol (800 nmol/kg) blocked the increase in dopamine as well as noradrenaline in the medial prefrontal cortex. |
2002-02-21 |
2023-08-12 |
Not clear |
| M Markianos, J Hatzimanolis, L Lykoura. Neuroendocrine responsivities of the pituitary dopamine system in male schizophrenic patients during treatment with clozapine, olanzapine, risperidone, sulpiride, or haloperidol. European archives of psychiatry and clinical neuroscience. vol 251. issue 3. 2002-02-06. PMID:11697576. |
atypical antipsychotic drugs, in clinical doses, occupy 5-ht2 receptors near saturation, while d2 dopamine receptors, assessed usually in striatum by spect or pet methods, are occupied to different degrees.we hypothesized that these differences in d2 receptor occupancies may also be evaluated by a neuroendocrine approach, namely by measuring the plasma prolactin responses to i. m. administered haloperidol, since the expected elevations depend mainly on the free remaining d2 receptors in the tuberoinfundibular tract. |
2002-02-06 |
2023-08-12 |
Not clear |
| A J Wintink, S M Brudzynsk. The related roles of dopamine and glutamate in the initiation of 50-kHz ultrasonic calls in adult rats. Pharmacology, biochemistry, and behavior. vol 70. issue 2-3. 2002-02-05. PMID:11701203. |
higher dose of intracerebral glutamate alone (34 microg) significantly increased the number of 50-khz calls, which was completely reversed by systemic application of haloperidol (2 mg/kg), a dopamine antagonist. |
2002-02-05 |
2023-08-12 |
rat |
| M A Persinger, R P O'Connor, Y R Bureau, G H Parker, O Peredery, M Zegi. Synergistic induction of severe hypothermia (poikilothermia) by limbic seizures, acepromazine and physical restraint: role of noradrenergic alpha-1 receptors. Pharmacology, biochemistry, and behavior. vol 70. issue 2-3. 2002-02-05. PMID:11701206. |
administration of the specific and nonspecific dopamine antagonists haloperidol, chlorpromazine, sch23390, or clozapine did not simulate the effect at clinically effective dosages. |
2002-02-05 |
2023-08-12 |
rat |
| C A Heidbreder, R Foxton, J Cilia, Z A Hughes, A J Shah, A Atkins, A J Hunter, J J Hagan, D N Jone. Increased responsiveness of dopamine to atypical, but not typical antipsychotics in the medial prefrontal cortex of rats reared in isolation. Psychopharmacology. vol 156. issue 2-3. 2002-01-28. PMID:11549234. |
the present series of experiments sought to investigate the effect of clozapine (5-10 mg/kg s.c.), olanzapine (5 mg/kg s.c.), and haloperidol (0.5 mg/kg s.c.) on dopamine (da) and amino acids in the prelimbic/infralimbic subregion of the mpfc in group- and isolation-reared rats. |
2002-01-28 |
2023-08-12 |
rat |
| C Belzung, A M Le Guisquet, S Barreau, F Calatayu. An investigation of the mechanisms responsible for acute fluoxetine-induced anxiogenic-like effects in mice. Behavioural pharmacology. vol 12. issue 3. 2002-01-25. PMID:11485052. |
the drugs used included the benzodiazepine diazepam, the 5-ht1a receptor partial agonist buspirone, the 5-ht1a receptor antagonists pindolol and way-100635, the non-selective 5-ht2 receptor antagonists methiothepin, mianserin and ritanserin, the non-selective dopamine (da) receptor antagonist haloperidol, the d1 antagonist sch23390, the selective d2 antagonist raclopride, the d2/3 agonist quinelorane, the cholecystokininb (cck(b)) receptor antagonist ly 288513, and the corticotropin-releasing factor1 (crf1) receptor antagonist cp-154,526. |
2002-01-25 |
2023-08-12 |
mouse |
| M Levite, Y Chowers, Y Ganor, M Besser, R Hershkovits, L Cahalo. Dopamine interacts directly with its D3 and D2 receptors on normal human T cells, and activates beta1 integrin function. European journal of immunology. vol 31. issue 12. 2002-01-24. PMID:11745370. |
the dopamine receptor agonists bromocriptine and pergolide mimic the direct effect of dopamine on the beta1 integrin function, while the dopamine receptor antagonists butaclamol and haloperidol suppress it, suggesting additional signaling via the dopamine d2 receptor subtype. |
2002-01-24 |
2023-08-12 |
human |
| M P Castelli, I Mocci, A M Sanna, G L Gessa, L Pan. (-)S amisulpride binds with high affinity to cloned dopamine D(3) and D(2) receptors. European journal of pharmacology. vol 432. issue 2-3. 2002-01-16. PMID:11740949. |
the interaction of racemic (+/-)rs amisulpride and its two enantiomers (+)r and (-)s with dopamine d(2) and dopamine d(3) receptors subtypes were compared with that of haloperidol. |
2002-01-16 |
2023-08-12 |
human |