| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S Kähkönen, J Ahveninen, I P Jääskeläinen, S Kaakkola, R Näätänen, J Huttunen, E Pekkone. Effects of haloperidol on selective attention: a combined whole-head MEG and high-resolution EEG study. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 25. issue 4. 2001-11-01. PMID:11557163. |
taken together, haloperidol seemed to induce functional changes in neural networks accounting for both selective and involuntary attention, suggesting modulation of these functions by dopamine d2 receptors. |
2001-11-01 |
2023-08-12 |
human |
| A Ouagazzal, A J Grottick, J Moreau, G A Higgin. Effect of LSD on prepulse inhibition and spontaneous behavior in the rat. A pharmacological analysis and comparison between two rat strains. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 25. issue 4. 2001-11-01. PMID:11557170. |
the dopamine da(2like) receptor antagonist, haloperidol (0.1 and 0.2 mg/kg, s.c.), was without effect against an lsd-induced disruption of ppi. |
2001-11-01 |
2023-08-12 |
rat |
| B Weber, E Schlicker, P Sokoloff, H Star. Identification of the dopamine autoreceptor in the guinea-pig retina as D(2) receptor using novel subtype-selective antagonists. British journal of pharmacology. vol 133. issue 8. 2001-10-25. PMID:11498509. |
the aim of the present study was to determine the receptor subtype (d(2) vs d(3)) involved in the inhibition of dopamine release in guinea-pig retinal discs, using established (haloperidol, (s)-nafadotride) and novel dopamine receptor antagonists (st-148, st-198). |
2001-10-25 |
2023-08-12 |
human |
| M El Yacoubi, C Ledent, M Parmentier, R Bertorelli, E Ongini, J Costentin, J M Vaugeoi. Adenosine A2A receptor antagonists are potential antidepressants: evidence based on pharmacology and A2A receptor knockout mice. British journal of pharmacology. vol 134. issue 1. 2001-10-11. PMID:11522598. |
administration of the dopamine d2 receptor antagonist haloperidol (50 - 200 microg kg(-1) i.p.) |
2001-10-11 |
2023-08-12 |
mouse |
| P J Pauwels, S Tardif, T Wurch, F C Colpaer. Real-time analysis of dopamine: antagonist interactions at recombinant human D2long receptor upon modulation of its activation state. British journal of pharmacology. vol 134. issue 1. 2001-10-11. PMID:11522600. |
dopamine antagonists were unable to block the transient high-magnitude ca(2+) phase at the wild-type d2long receptor upon simultaneous exposure to antagonist and dopamine, while full blockade of the low-magnitude ca(2+) phase did occur at a later time (onset-time: haloperidol < bromerguride < (+)-butaclamol). |
2001-10-11 |
2023-08-12 |
human |
| M W Hale, S F Crow. The effects of apomorphine and haloperidol on memory consolidation in the day-old chick. Behavioral neuroscience. vol 115. issue 2. 2001-09-27. PMID:11345962. |
pretreatment with the dopamine antagonist haloperidol eliminated the memory disturbance induced by apomorphine and facilitated consolidation of memory in chicks given a weak (20% vol/vol methyl anthralinate) training experience. |
2001-09-27 |
2023-08-12 |
chicken |
| N M de Bruin, B A Ellenbroek, E L van Luijtelaar, A R Cools, K E Steven. Hippocampal and cortical sensory gating in rats: effects of quinpirole microinjections in nucleus accumbens core and shell. Neuroscience. vol 105. issue 1. 2001-09-27. PMID:11483310. |
also, effects of the dopamine d2 receptor antagonist haloperidol (0.1 mg/kg, subcutaneously) as pretreatment were studied. |
2001-09-27 |
2023-08-12 |
human |
| K Nakamura, M Kurasaw. Anxiolytic effects of aniracetam in three different mouse models of anxiety and the underlying mechanism. European journal of pharmacology. vol 420. issue 1. 2001-08-30. PMID:11412837. |
the anxiolytic effects were completely blocked by haloperidol and nearly completely by mecamylamine or ketanserin, suggesting an involvement of nicotinic acetylcholine, 5-ht2a and dopamine d2 receptors in the anxiolytic mechanism. |
2001-08-30 |
2023-08-12 |
mouse |
| A Gjedde, D F Won. Quantification of neuroreceptors in living human brain. v. endogenous neurotransmitter inhibition of haloperidol binding in psychosis. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 21. issue 8. 2001-08-23. PMID:11487734. |
the authors used positron emission tomography to test the hypothesis that haloperidol's ic50 toward the binding of tracer n-[11c]methylspiperone ([11c]nmsp) in brain must be increased in patients in whom more dopamine is bound to receptors than in healthy volunteers. |
2001-08-23 |
2023-08-12 |
human |
| M El Yacoubi, C Ledent, M Parmentier, J Costentin, J M Vaugeoi. Adenosine A2A receptor knockout mice are partially protected against drug-induced catalepsy. Neuroreport. vol 12. issue 5. 2001-08-09. PMID:11303773. |
catalepsy assessed using the bar test was measured in both adenosine a2a receptor knockout (a2ar ko) and wild-type (a2ar wt) mice submitted to acute administration of the dopamine d2 receptor antagonist haloperidol (0.5, 2, 4, 6 mg/kg i.p. |
2001-08-09 |
2023-08-12 |
mouse |
| T Yoshikawa, N Yoshida, M Ok. The broad-spectrum anti-emetic activity of AS-8112, a novel dopamine D2, D3 and 5-HT3 receptors antagonist. British journal of pharmacology. vol 133. issue 2. 2001-08-02. PMID:11350861. |
domperidone and haloperidol, which have affinity for dopamine d3 receptor, also inhibited r(+)-7-oh-dpat-induced hypothermia. |
2001-08-02 |
2023-08-12 |
mouse |
| C K Hwang, U M D'Souza, A J Eisch, S Yajima, C H Lammers, Y Yang, S H Lee, Y M Kim, E J Nestler, M M Mouradia. Dopamine receptor regulating factor, DRRF: a zinc finger transcription factor. Proceedings of the National Academy of Sciences of the United States of America. vol 98. issue 13. 2001-07-26. PMID:11390978. |
mice treated with drugs that increase extracellular striatal dopamine levels (cocaine), block dopamine receptors (haloperidol), or destroy dopamine terminals (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) show significant alterations in drrf mrna. |
2001-07-26 |
2023-08-12 |
mouse |
| J A Zackheim, E D Abercrombi. Decreased striatal dopamine efflux after intrastriatal application of benzazepine-class D1 agonists is not mediated via dopamine receptors. Brain research bulletin. vol 54. issue 6. 2001-07-26. PMID:11403986. |
however, intrastriatal application of the less selective d2 antagonist haloperidol (1 microm) did prevent the decrease in striatal dopamine efflux observed during intrastriatal (+/-)-skf 82958 application. |
2001-07-26 |
2023-08-12 |
Not clear |
| K J Kovács, M Csejtei, I Laszlovszk. Double activity imaging reveals distinct cellular targets of haloperidol, clozapine and dopamine D(3) receptor selective RGH-1756. Neuropharmacology. vol 40. issue 3. 2001-07-19. PMID:11166331. |
double activity imaging reveals distinct cellular targets of haloperidol, clozapine and dopamine d(3) receptor selective rgh-1756. |
2001-07-19 |
2023-08-12 |
rat |
| P Brun, M Leonetti, F Sotty, R Steinberg, P Soubrié, B Renaud, M F Suaud-Chagn. Endogenous neurotensin down-regulates dopamine efflux in the nucleus accumbens as revealed by SR-142948A, a selective neurotensin receptor antagonist. Journal of neurochemistry. vol 77. issue 6. 2001-07-19. PMID:11413237. |
like the first-generation compound sr-48692, sr-142948a did not affect the tonic and evoked dopamine efflux, but dose-dependently enhanced haloperidol (50 microg/kg, i.p.) |
2001-07-19 |
2023-08-12 |
rat |
| N Sharan, V D Nair, R K Mishr. Modulation of a 40-kDa catecholamine regulated protein by dopamine receptor antagonists. European journal of pharmacology. vol 413. issue 1. 2001-07-12. PMID:11173065. |
chronic treatment with dopamine d2 receptor antagonist haloperidol in rats significantly increased the levels of crp40 in the striatum, whereas, chronic r(+)-7-chloro-8-hydroxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1h-3-benzazepine (sch 23390) dopamine d1 receptor antagonist administration significantly decreased striatal crp40 levels. |
2001-07-12 |
2023-08-12 |
rat |
| T D Sotnikova, R R Gainetdinov, T V Grekhova, K S Rayevsk. Effects of intrastriatal infusion of D2 and D3 dopamine receptor preferring antagonists on dopamine release in rat dorsal striatum (in vivo microdialysis study). Pharmacological research. vol 43. issue 3. 2001-07-12. PMID:11401421. |
the difference between effects of d2 and d3 dopamine receptor preferring antagonists applied locally was observed only in the degree of dopamine release elevation [the maximal responses were about 160% for haloperidol and spiperone, 190% for clozapine and ( +)-uh232 and 400% for ( +)-aj76, of basal]. |
2001-07-12 |
2023-08-12 |
rat |
| T Araki, H Mizutani, M Matsubara, Y Imai, M Mizugaki, Y Itoyam. Nitric oxide synthase inhibitors cause motor deficits in mice. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 11. issue 2. 2001-07-05. PMID:11313158. |
we investigated possible motor effects of 7-nitroindazole (7-ni), an neuronal nitric oxide synthase (nnos) inhibitor, and n(g)-nitro-l-arginine methyl ester (l-name), an non-selective nos inhibitor in mice using catalepsy and pole tests in comparison with dopamine d(2) receptor antagonist, haloperidol. |
2001-07-05 |
2023-08-12 |
mouse |
| T Araki, H Mizutani, M Matsubara, Y Imai, M Mizugaki, Y Itoyam. Nitric oxide synthase inhibitors cause motor deficits in mice. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 11. issue 2. 2001-07-05. PMID:11313158. |
for dopamine, dopac and hva contents, haloperidol exhibited a significant decrease in dopamine content and a significant increase in dopac and hva content in the striatum. |
2001-07-05 |
2023-08-12 |
mouse |
| T Araki, H Mizutani, M Matsubara, Y Imai, M Mizugaki, Y Itoyam. Nitric oxide synthase inhibitors cause motor deficits in mice. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 11. issue 2. 2001-07-05. PMID:11313158. |
these results demonstrate that nos inhibitors as well as dopamine d(2) receptor antagonist haloperidol can induce motor deficit in mice. |
2001-07-05 |
2023-08-12 |
mouse |